51 Lofts for Lease in Rochester, NY, USA

East Rochester Coworking for Lease - Southeast

Hit your numbers at Commercial Street, East Rochester. Boost your networking opportunities and business profile with sought-after office space in East Rochester. Located just off Interstate 490, Commercial Street is easy to reach and has plenty of parking nearby. Commuting by bus is just as effortless with Commercial & Washington Bus Stops a 3-minute walk away. If work takes you further afield, you’re only a 20-minute drive from Frederick Douglass Greater Rochester International Airport ROC. Choose the duration of your stay. Use the office space a few hours a week or base your business here long-term. Whatever your ambition, we have the time and space for your next project. Designed to encourage productivity, our flexible office space has the privacy and space your business needs. Hold your next big pitch or presentation in our spacious meeting rooms fitted with the latest videoconferencing technology. Find focus in private office space or maximize your chances of collaboration in our open-plan coworking spaces. Head to our fully stocked kitchen for refreshments or catch up with colleagues in our informal breakout spaces. When the working day is done, step outside the office and into the plaza and take your pick from one of the many shops, restaurants and leisure facilities on your doorstep in this thriving neighborhood. Find a place to thrive at Regus 333 W Commercial Street: • Professional Offices: Elegant office space equipped with modern furniture and amenities, easily scalable for individual professionals or entire teams. Move into a turnkey office, pay by day, or custom tailor a unique suite to accelerate organizational success. • Community: Work wherever you need to be and discover a dynamic mix of businesses and like-minded individuals. Regular networking and personal growth events and sociable workspaces foster collaboration and open new opportunities for your business. • Virtual Workspace: Build your presence anywhere in the world with a new virtual address. Whether simply to forward mail, hold a meeting, or even answer calls, Regus’ virtual offices have the services you need. • Collaboration: Host a meeting in every major city in the world and impress local clients with industry-leading technologies in one of the fully serviced meeting spaces. There is a room for every need with day-of booking for anything from private conference rooms to inspiring training spaces. • Join the Club: Regus’ thriving global network of beautifully designed offices provides the flexibility to work anywhere and everywhere. Reserve space on the move via the Regus app and get to work from any of the business lounges, dedicated desks, or your own private office. All images shown in this listing belong to Regus’ locations but may not correspond to this specific center.

Property Type:

Office

Date on Market:

2025-03-25

Rochester Office for Lease - Greater Rochester

1344-1350 University Avenue is a highly adaptable flex facility in Rochester, New York. The 120,000-square-foot building is newly renovated and offers excellent exposure along the lively University Avenue corridor. Recent capital improvements include an updated façade, a brand-new roof, and upgraded HVAC and electrical systems. High ceilings and exposed brick and beam details are found throughout the building. Additional property features include on-site surface parking, six loading docks, an immersive double-height lobby, large windows, and natural light-flooded interiors. This location is available for immediate occupancy. Join a diverse mix of established tenants, including Black Button Distilling, Nine Maidens Brewing Company, Rochester Parkour, and professional and service businesses. Envision this ideal space for your events, tech company, or even fitness spa. The landlord can build-to-suit to meet all tenant specifications. 1344-1350 University Avenue is located just east of Downtown Rochester in the vibrant East Avenue neighborhood. Surrounding points of interest include restaurants, bars, retail and grocery stores, the Rochester Museum & Science Center, and the charming Cobbs Hill neighborhood. The property is convenient to Interstate 490 and Interstate 590 access and a short drive to Cobbs Hill Park. A growing population of approximately 308,250 residents live within a 5-mile radius of 1344-1350 University Avenue, representing an average household income of nearly $75,000 annually.

Property Type:

Flex

Date on Market:

2025-11-19

Rochester Multiple Space Uses for Lease - Northwest

Located on the corner of Maiden Lane and Long Pond Road, this popular plaza features both retail and office space. Some tenants include Domino's Pizza, Orien's Cafe, Family First Federal Credit Union, Barry's Power Yoga, and much more!

Date on Market:

2026-03-23

West Henrietta Flex for Lease - South Central

Date on Market:

2023-09-06

Pittsford Office for Lease - Southeast

Date on Market:

2026-03-19

Webster Office for Lease - Northeast

A well-maintained, two-story commercial building on a corner lot in the Village of Webster with off street parking, natural light on multiple sides, and a clean, neutral finish ready to be made your own. Zoned G-I (General Industrial), one of the most flexible designations in the Village, the space accommodates a wide range of uses including professional offices, health and wellness practices, specialty retail, and more. The first floor offers five private rooms, two half bathrooms, and storage, while the second floor provides three additional private rooms and a full bathroom. This layout is well suited for businesses that benefit from separating client-facing space from back-office or administrative functions.

Property Type:

Flex

Date on Market:

2026-02-16

Rochester Office, Office/Medical for Lease - Greater Rochester

Office buildings in center of Greater Rochester, approx 1 mile from UR/Strong Campus, featuring 75,000 SF complex with offices tailored to medical and general. Property includes direct access from parking to ground floor suites. The property also features basement support space with bathrooms, open conference rooms, break rooms and private offices for end of the day use.

Date on Market:

2026-01-09

Rochester Office for Lease - Greater Rochester

Date on Market:

2026-03-18

Rochester Office for Lease - Rochester CBD

Date on Market:

2025-05-01

Rochester Office/Retail for Lease - Greater Rochester

Artwalk Center is a distinctive, multi-building campus located just off University Avenue in Rochester’s Neighborhood of the Arts, encompassing 840–860 University Ave and 2–4 Elton Street. Built incrementally over several decades as the campus evolved, the buildings reflect a range of architectural eras while sharing a common industrial character that has been thoughtfully adapted for modern use. At the heart of Artwalk Center is 4 Elton Street, originally constructed in 1911 as a purpose-built printing plant. Designed to support heavy presses, the building features extra-thick concrete floors, soaring ceiling heights, exposed brick walls, and substantial timber columns. A sloped, indoor truck ramp was incorporated to allow delivery vehicles to back directly into the building, enabling year-round loading and unloading. These industrial details remain visible today, lending the space its distinctive character more than a century later. Collectively, Artwalk Center is now home to a diverse mix of professional, creative, and service-oriented tenants, including Fiamma Restaurant, The William and Sheila Konar Foundation, Rochester Specialty Dental, Park & Berkeley Properties, Universal Kempo Club, Assemblymember Harry Bronson, Wendy At Work, Axe of Kindness Tattoo, and several other locally rooted businesses. Together, the campus continues a long tradition of craftsmanship and entrepreneurship, evolving from its industrial origins into a vibrant hub within one of Rochester’s most dynamic neighborhoods.

Property Type:

Office

Date on Market:

2025-08-29

East Rochester Multiple Space Uses for Lease - Southeast

Welcome to Pianoworks, a premier office and retail destination in East Rochester, NY. Located at 349 W Commercial St, this historic building, once home to the American Piano Company, has been transformed into a modern business hub, offering versatile commercial spaces in a professional and well-maintained setting. Pianoworks provides flexible office layouts designed to accommodate businesses of all sizes, from startups to established enterprises. The property also features prime retail spaces with excellent visibility and accessibility. With ample on-site parking, modern infrastructure, and a strategic location just minutes from I-490 and downtown Rochester, Pianoworks is an ideal choice for businesses looking to establish or expand their presence in the area. Enjoy the benefits of a historic property with modern upgrades, a thriving business community, and a location that offers convenience for both employees and customers. Discover the perfect workspace at Pianoworks – where business and history come together for success.

Date on Market:

2026-03-20

Spencerport Retail for Lease - Northwest

Discover a fantastic leasing opportunity in a well-established plaza with multiple other tenants, attracting steady foot traffic. First space is 1,300 SF and features large glass windows that provide excellent natural light and high visibility. Currently built out as a fully turn-key hair salon, the space includes 3 modern cutting stations, 2 shampoo bays (with room to add 2 more), and 3 private treatment rooms ideal for tanning, massage, or other spa services. Second space is 1350 sqft and is fully gutted. Owner is willing to make changes. Spaces can also be combined

Date on Market:

2025-06-11

Rochester Office/Medical for Lease - Northwest

Professional office (4,000 RSF) located in busy office park next to Unity Hospital and busy Ridgeway medical corridor. Private entrance, general reception, and offices/treatment rooms, a staff bathroom. Medical, optical, personal services - opportunities unlimited. Immediately off the Interstate 390 expressway at Ridgeway Ave near Long Pong Rd. and less than 1/2 mile from Unity Hospital campus and Dialysis Center on Long Pond. ENTIRE PROPERTY IS ALSO AVAILABLE FOR PURCHASE. Seller financing is an option. Asking $5,900/month. Includes all except utilities.

Property Type:

Office

Date on Market:

2024-02-02

Rochester Office for Lease - Greater Rochester

Property Type:

Industrial

Date on Market:

2024-12-19

Rochester Office, Office/Medical for Lease - Northeast

3000 E Ridge Road is a prestigious office building in Rochester, New York. Spanning 45,568 square feet on a single level, it is ideal for a regional or national company to establish its corporate headquarters or divide to accommodate multiple tenants. The building is designed to meet various professional office needs, and a portion can also be converted to support medical office use. Renovated in 2019, the campus-like setting offers a range of amenities, including a state-of-the-art conference facility, training and break rooms, controlled access, partitioned offices, and abundant natural light. Tenants also benefit from a backup generator, heavy electric capacity, a dedicated server room, and 20,000 square feet of basement storage. The property includes over 300 surface parking spaces for employees and clients and a spacious outdoor picnic area for relaxation. 3000 E Ridge Road is conveniently located within a 15- to 20-minute drive of Downtown Rochester, the Rochester Amtrak Station, and Frederick Douglass Greater Rochester International Airport. Tenants also enjoy direct access to Interstate 590 and NY Route 104. Nestled in a residential setting, the campus has amenities, including shopping centers, public schools, Riedman Health Center, and Rochester General Hospital. National retailers and businesses like Walmart Supercenter, Target, Starbucks, Wegmans, Dollar Tree, and Holiday Inn Express Rochester are all within a 3-mile radius. In the thriving Rochester metropolitan area, 3000 E Ridge Road benefits from a robust market known for its high-tech industries, including advanced manufacturing, life sciences, and software/IT. The region is home to prominent institutions such as the Rochester Institute of Technology and the University of Rochester, which produce graduates with in-demand programming, data mining, and cybersecurity skills. 3000 E Ridge Road presents a compelling opportunity for businesses to establish or expand their presence in a dynamic and growing market supported by a well-educated labor force.

Date on Market:

2026-03-02

Rochester Office, Retail for Lease - Rochester CBD

Benchmark Realty Advisors is pleased to present the Historic Valley Building on East Avenue for Lease. Recently purchased by a local developer, The Valley Building offers numerous Office & Retail Space configurations. The site features an interior 50+ Car Parking Garage built by the original developer, Valley Cadillac Corporation, for their inventory in the early 1940 to 1970’s. The building also offers nearby surface parking lots in addition. Several Office Suites have been recently renovated to offer turn-key availability with abundant natural light throughout. Entire contiguous floorplates can also be made available for the right users of approximately +/-20,000 SF. (2) Retail storefronts on East Avenue range in size from -/+ 1,350 - 3,500 SF, a large End Cape former bar/recreation space with office mezzanine, along with a former Bar/Restaurant space next to Albunn Coffee House.

Date on Market:

2025-12-31

Rochester Retail for Lease - Greater Rochester

Bank building located on the corner of Waring Rd and Master St. Outparcel in Waring Plaza.

Date on Market:

2023-07-07

Rochester Flex, Industrial for Lease - Greater Rochester

850 St Paul is a converted 19th century buckle factory and has distribution/manufacturing/warehouse space available for lease. Property 5 minutes from downtown Rochester and all expressways. Fully automated fenced parking lot. Loading docks with 2 ton lifting crane and multiple grade level docks with overhead doors. Full time maintenance personnel on premise. Fork lift operators available during normal business hours to unload vehicles. Currently there is a 12,000sf space available. Willing to paint and prep space as needed based on term of lease. $6.00 - $6.50/sqft, Fully Gross plus electric. Call listing Broker for details and showing times/instructions. Contact Leverage Properties LLC @ 585.329.4205 or visit www.leveragepropertiesllc.com

Date on Market:

2026-03-26

Penfield Office/Retail for Lease - Northeast

Located in the vibrant 4 Corners District of Penfield, this recently renovated office space is perfect for a small business. Offering ample on-site parking, this single-room unit provides a comfortable and efficient workspace. Ideal for entrepreneurs, professionals, or small teams seeking a convenient and modern location.

Property Type:

Office

Date on Market:

2026-02-17

Rochester Office/Retail for Lease - Southeast

Opportunity to lease space in a popular neighborhood retail center in Rochester, New York off Monroe Avenue. The Pittsford Plaza has a diverse tenant roster and is anchored by Trader Joes and TJ Max. Very well maintained and renovated within the last 5 years, offering excellent parking within a very active shopping center. The great location is at the intersection of major thoroughfares providing excellent exposure, seeing an average traffic count of 57,000 vehicles per day.

Date on Market:

2025-07-18

Rochester Office for Lease - Greater Rochester

Four-story office building with large windows for natural light. Located conveniently within a mile of I-390 and directly across from the Greater Rochester International Airport. 24/7 secure access and plentiful parking!

Date on Market:

2023-08-31

Rochester Office for Lease - Rochester CBD

Professional office building, conveniently located downtown near the Inner Loop and 490. Surface parking available, close to popular restaurants. Renting "AS-IS", $8/SF modified gross.Adjacent to the new/improved waterfront park or centrally located to multiple Roc the Riverway improvements.

Date on Market:

2026-03-11

Rochester Flex for Lease - South Central

Built in 1996, this 26,000 SF freestanding single story modern masonry building sits on 3.62 acres. The available suite is a 9,006 SF very nice office space with a reception area, conference room, break room, restrooms and multiple private offices.

Property Type:

Industrial

Date on Market:

2023-03-13

Rochester Office/Retail for Lease - Greater Rochester

Outparcel --- Former bank building with drive-thru and onsite walk-in safe. Immediate occupancy available with flexible terms. Perfect for restaurant, pharmacy and bank.

Date on Market:

2023-07-04