35 Storefront Properties for Lease in Saint Louis, MO, USA

University City Office for Lease - Creve Coeur/Hwy-67

Louis London Annex on Delmar Boulevard presents a strategically positioned ground-floor retail opportunity, ideal for a café, salon, or cell phone store. With thoughtful build-out modifications, the space can also accommodate a variety of retail concepts, including yoga or Pilates studios. Above, the mixed-use building offers premium office space featuring a mix of open work areas and private perimeter offices, providing a dynamic environment for businesses of all sizes. Flexible floor plans cater to various needs, making this an exceptional opportunity for companies seeking a prestigious and adaptable setting in a prime location. Louis London Annex is situated on University City's main artery, Delmar Boulevard, frequented by approximately 20,000 vehicles daily. In the heart of the Delmar Loop district, this property is walkable to a wide array of boutique shopping, hip restaurants, and entertainment. The Loop Trolley stop is conveniently in front of the building for the 2-mile streetcar line from St. Louis to University City. Set up space at Louis London Annex, where businesses, from wellness studios and salons to tech retailers and more, can benefit from exceptional visibility and a sought-after St. Louis suburb.

Date on Market:

2025-02-04

Saint Louis Office for Lease - St Louis City

The Central West End's historic Bacchus Building.

Property Type:

Retail

Date on Market:

2026-03-26

Webster Groves Office for Lease - Brentwood/Maplewood

This 3,600± SF available two-story office property (1,800± SF per level) offers flexible use with dual private entrances, allowing each floor to operate independently. Large storefront windows provide abundant natural light, complemented by a side garden and outdoor seating area. Situated at the high-traffic intersection of Gore and Lockwood Avenue, the property includes five on-site parking spaces plus ample street and structured parking. Recent upgrades feature new energy-efficient HVAC systems. Located within a strong business corridor and walkable to Old Webster’s dining and retail district, this is an ideal opportunity for office or boutique users.

Date on Market:

2026-03-18

Affton Office for Lease - South County

4808 Forman Rd. St. Louis, MO 63123 1,225-2,500 SF AVAILABLE FOR LEASE Neighborhood retail opportunity in a well-established residential corridor. Two-story building with flexible suite options on both the upper and lower levels. Available Spaces: Upper Level: 1,225 SF Lower Level: 1,250 SF Maximum Contiguous: 2,475 SF Ideal for service-based businesses, boutique retail, insurance offices, grooming services, or specialty shops. Located within a stable community with strong household incomes and consistent neighborhood traffic. Lease Rates: UPPER LEVEL LEASE RATE: $16.00/SF LOWER LEVEL LEASE RATE: $13.00/SF GROSS LEASE - TENANT RESPONSIBLE FOR UTILITIES ONLY. CONTACT: Kim Richter - 314.333.9844 krichter@mckelveyproperties.com

Property Type:

Retail

Date on Market:

2026-03-17

Saint Louis Office/Retail for Lease - St Louis City

High-visibility corner retail space at the northeast intersection of Lindell Boulevard and Vandeventer Avenue — one of St. Louis's most trafficked corridors, directly across from Saint Louis University. Rental price includes electric. • 1,300 SF ground-level storefront • Premier corner exposure with signage potential on two major streets • On-street parking (metered by City of St. Louis), with high level of pedestrian traffic • Electric, trash and sewer included in lease rate (you pay gas and internet) • Recently updated electrical service, plumbing, and HVAC • Space delivered ready to reconfigure to suit your business Ideal uses include boutique retail, salon or barbershop, professional services, wellness studio, gallery, or creative office. (Note: commercial kitchen exhaust hood installation is not permitted.) Situated in the heart of Midtown, this location benefits from heavy daily foot and vehicle traffic driven by SLU's campus, the Grand Center Arts District, and surrounding medical institutions. Strong transit access via MetroLink and MetroBus. Qualified tenants must demonstrate excellent credit and a strong business history or viable business plan.

Property Type:

Multifamily

Date on Market:

2026-03-10

Saint Louis Flex for Lease - CBD

Prime Olive St Storefront at Paul Brown Loft Apartments Showcase your business in a high-visibility storefront located in the heart of downtown St. Louis. The street-level commercial space at Paul Brown Loft Apartments places your business in one of downtown St. Louis’ most recognizable historic buildings and in the heart of the entertainment corridor. The location sits steps from the convention center and surrounded by established restaurants including Mizu Sushi, Sen Thai Asian Bistro, Rooster, and Sugarfire Smokehouse, creating steady foot traffic from residents, office workers, and visitors. This property is a recent addition to the Olive Holding portfolio. The company has renovated nearly 1,000 loft apartments throughout downtown and is actively repositioning street-level storefronts like this one into vibrant neighborhood amenities for residents, condo owners, hotel guests, and convention-center visitors. The area is evolving quickly—this is an opportunity to join a growing, energized downtown community. Key Features • Listed lease rate plus proportional share of utilities • Fully built-out retail space—move-in ready • Located in-line with other active storefronts • Space is in excellent condition • Central air and heating • Private restrooms • High ceilings with exposed elements • Plug-and-play layout • After-hours HVAC available • Finished ceiling height: 17 ft • Tall ceilings and a high-visibility storefront ideal for branding This prominent commercial building at 210 North 9th Street offers excellent exposure, modern upgrades, and unbeatable walkability to the city’s top amenities. - Street-level storefront ideal for retail, service businesses, or client-facing operations - Variety of suites available to fit different business sizes and layouts - Walking distance to restaurants, retail, transit, and all downtown conveniences - Modern, renovated main lobby that creates a strong professional impression - High-speed fiber internet for fast, reliable connectivity - Perfect for businesses seeking both visibility and a central downtown presence A standout opportunity for any business looking to establish itself in a thriving, walkable urban location. We have a 1,079 sq ft commercial space now available for lease. This versatile unit is ideal for a variety of business types and offers excellent visibility and foot traffic. We’re seeking a 5-year lease term.

Date on Market:

2026-03-06

Saint Louis Retail for Lease - CBD

Prime Washington Avenue location in downtown St. Louis -- steps from the convention center, near established restaurants such as Mizu Sushi, Sen Thai Asian Bistro, Rooster & Sugar Fire Smokehouse. This property is a new acquisition within the Oliver Properties portfolio. Oliver Properties has purchase and renovated ~1,000 loft apartments in the neighborhood and is repositioning street-level storefronts like this one as new neighborhood amenities for apartment dwellers, condo owners, convention center/hotel visitors, office users, ... come be a part of this fast-changing downtown neighborhood.

Date on Market:

2026-02-20

Saint Louis Retail for Lease - South County

Family owned strip center at the corner of Tesson Ferry and Baptist Church Road.

Date on Market:

2026-01-15

Saint Louis Retail for Lease - St Louis City

Suite 5826 offers an excellent opportunity to lease a ±865 SF street-level retail space along the highly visible South Grand Boulevard corridor. Positioned on the 1st floor, this space benefits from strong pedestrian and vehicular traffic in a well-established mixed-use area.5818 Just came available which has been a barber/salon for the past 20 years. The suite features an efficient, open layout suitable for a variety of retail or service-oriented uses, with flexible lease terms available. The storefront location provides excellent exposure and signage potential, making it ideal for neighborhood-serving businesses looking to establish a presence in a vibrant commercial district. The property is surrounded by dense residential neighborhoods and nearby retailers, restaurants, and public transportation, supporting consistent foot traffic and customer accessibility.

Property Type:

Multifamily

Date on Market:

2026-01-12

Saint Louis Retail for Lease - St Louis City

Demographics within a 1-mile radius reflect a population of over 20,000 with an average household income exceeding $112,000, while the 3-mile radius includes over 130,000 residents. The Central West End is known for its eclectic food scene, historic architecture, and proximity to cultural landmarks, making it one of the most desirable neighborhoods in the region for both residents and businesses. This retail space benefits from exposure to multiple high-traffic corridors, including 137,433 vehicles per day along nearby thoroughfares. Tenants will enjoy the synergy of neighboring institutions and entertainment destinations such as City Foundry, The Grove, and St. Louis University.

Property Type:

Multifamily

Date on Market:

2025-11-20

Saint Louis Retail for Lease - St Louis City

Sitting in the heart of Botanical Heights neighborhood this property sits in a very walkable to many residential properties and other popular small businesses including La Patisserie Chouquette, Union Loafers, AO & Co, Taco Budda and No Ordinary Rabbit.

Date on Market:

2025-07-29

Saint Louis Office for Lease - Clayton

Great Location for Your Retail/Office! Located off of S Big Bend and Clayton Rd, this is a unique opportunity to make your business centrally located with GREAT visibility and traffic count.

Property Type:

Retail

Date on Market:

2025-07-28

Saint Louis Retail for Lease - CBD

2639 Locust St, Saint Louis, MO 63103 has a 2,125 SF retail/restaurant space available for lease. The street-level storefront borders the Edge of the City Commons and Midtown Alley neighborhoods, just blocks from the MLS CITYPARK Stadium (home of St. Louis City SC), Union Station, Enterprise Center, City Commons, and Grand Center. The space features 18' ceilings that flood the interior with natural light, a retractable storefront opening to a large front patio, exposed wood ceilings, new concrete floors, and bar rough-in with two restrooms. It’s designed as a build-to-suit bar or retail space to accommodate various tenant needs. The area is bustling, with over 27,700 employees working nearby daily, 17 restaurants and retail options within walking distance, and nearly 1,900 residential units occupied and under construction.

Date on Market:

2025-06-11

Saint Louis Retail for Lease - Clayton

Date on Market:

2025-02-14

Saint Louis Coworking for Lease - St Louis City

Property Type:

Retail

Date on Market:

2025-01-22

Saint Louis Retail for Lease - St Louis City

Date on Market:

2024-08-27

Saint Louis Office/Retail for Lease - Clayton

Property Type:

Retail

Date on Market:

2024-06-25

Saint Louis Retail for Lease - St Louis City

1500 SF Retail Bay Former Photography Studio - Easily Customizable to Suit Your Needs Convenient In-Unit Kitchenette and Bathroom High Foot Traffic Area Located in the Heart of Vibrant Grove Neighborhood Employee Parking In Rear Surrounded by Amenities and Adjacent to Urban Chestnut Brewery

Date on Market:

2026-03-10

Saint Louis Retail for Lease - St Louis City

Building recently underwent several major exterior renovations including new facade with black single-seam metal roof, new lighting system, new security camera system, new trash cans, and upgraded Alexian Plaza sign.

Date on Market:

2026-03-28

Saint Louis Retail for Lease - St Louis City

Date on Market:

2020-06-19

Maplewood Office for Lease - Brentwood/Maplewood

Property Type:

Retail

Date on Market:

2025-10-20

Clayton Retail for Lease

Date on Market:

2015-08-12

Maplewood Retail for Lease - Brentwood/Maplewood

Date on Market:

2018-04-23

Saint Louis Retail for Lease - Clayton

Prime Retail Location In The Heart Of Downtown Clayton with Unbeatable Visibility And Foot-Traffic. Neighboring Retailers Include Potbelly Sandwich Shop, Louie’s Wine Dive, and Bar & Cafe Napoli.

Date on Market:

2021-09-13