173 Storefront Properties for Lease in South Carolina, USA

Aiken Retail for Lease - Outlying Aiken County

Centre South, a diversified and established shopping center outside of Augusta, Georgia, now invites businesses to join its coactive mix of thriving tenants. Food Lion and USPS are currently the main traffic anchors of Centre South, complemented by a handful of financial services, salons, Happy Spirits, Aiken Antiques, and Habanero’s Mexican Grill. Centre South’s consumer base is soon to be invigorated and broadened by the opening of Back Nine Golf, which is currently building out its space. The indoor golf simulator chain is rapidly expanding nationwide, and this store comes after the brilliant success of its location 30 minutes away in Augusta. The landlord is open to various types of businesses, including daycares, specialty gyms, lifestyle and entertainment hubs, and more. Additionally, tenant improvement allowances and build-to-suit services are negotiable. Aiken, South Carolina, is a respectable retail submarket within the Greater Augusta metro. While the home of the Masters Tournament anchors much of the commercial landscape, outlying communities contribute to business success. Aiken’s average retail vacancy rate, which was reportedly half a percentage point lower than the broader market’s figure in Q4 2025. From a demographic perspective, the area’s full-time population has incomes well above the national average, and growth projections indicate a significant increase in households over the coming years.

Date on Market:

2025-06-12

Greenville Retail for Lease - Pelham/I-85

Establish a presence in one of Greenville’s most active and affluent corridors with this high-visibility suite offered via sublease. Pelham Hills Shopping Center is a prominent fixture of a larger mixed-use node at the crossing of Pelham Road and Interstate 85. Tenants will be joining a premier mix of daily traffic drivers in the vicinity, such as Walmart Supercenter, Topgolf, Lowes Foods, CVS, and dozens of local and national brand restaurants. The center offers ample parking and monument signage to capitalize on exposure. Suite B spans 1,250 square feet, and its adaptable layout is well-positioned for retail, office, medical, or professional services. It features a spacious interior with minimal column blockage to accommodate a variety of configurations. The suite also has sufficient plumbing hook-ups for water-intensive uses, such as specialty dental practices or small restaurants. High-profile residential and commercial hubs in the immediate area showcase the density of demand drivers. The Thornblade Country Club, Michelin’s North American headquarters, the Greenville Marriott, several large-scale industrial facilities, and over 2,400 apartment units are within a mile of Pelham Hills, just some of the locational elements that form a built-in consumer base. Affluent households are concentrated in this area, and the number continues to rise, with estimates calling for an annual household growth rate of 2% through 2029 within a 3-mile radius. These residents are naturally drawn to this area due to the aforementioned destinations and its strategic location along Interstate 85, making Pelham Hills Shopping Center a prime stop for commuter traffic and leisurely local visitors.

Date on Market:

2025-12-06

Greenville Retail for Lease - Woodruff/I-385 Corridor

Retail/Restaurant/Office use.

Date on Market:

2026-01-14

Charleston Retail for Lease - Downtown Charleston

Position your brand in the heart of Charleston’s iconic historic district with this premier retail opportunity at the corner of Market and Church Streets. Located steps from renowned dining, boutique shopping, and cultural landmarks, this property benefits from exceptional foot traffic and affluent demographics, with average household incomes exceeding $125,000 within a one-mile radius. The surrounding area is a magnet for both locals and tourists, ensuring consistent exposure and engagement. This corner unit has a loft for storage and/or office space. Sublease expiring 7/31/2032. Net sublease; Tenant to pay pro rata share of taxes and insurance. Available immediately once current tenant vacates. Security deposit of $7,827 due at sublease execution.

Date on Market:

2026-01-06

Greenville Retail for Lease - South Pleasantburg

1,650 SF of Retail / Office Space Includes: Lobby / Reception Area, Private Offices, Break Room & Storage Room Heavy Traffic Flow Zoned C-2 Minutes to Downtown Greenville, Restaurants, Shops, Interstate I85 & 385

Date on Market:

2025-12-30

Greenville Retail for Lease - West End

Wonderful ground floor space on Main Street in Greenville, SC Pedestrian friendly with outdoor sidewalk seating, if desired.

Date on Market:

2025-12-11

Greer Retail for Lease - Travelers Rest

Date on Market:

2025-12-09

Laurens Retail for Lease - Laurens County

Located in the heart of Downtown Laurens, SC, this beautifully restored two-story property presents an amazing leasing opportunity for a tenant seeking high visibility, professional appeal, and true character. Formerly constructed as a salon and later converted into a dance studio, the building is perfectly suited for a broad range of uses—whether as an upscale retail concept, a boutique food and beverage operation, or professional office suites. The property features ±2,200 square feet of usable space, with an ideal layout providing flexibility for a full-building lease or floor-by-floor occupancy. The main level offers an open, airy floor plan suitable for retail, service-based businesses, coffee shop, bakery, sushi restaurant, boutique fitness, or similar activations. The upper level includes multiple private rooms—large enough for conference tables or multiple desk setups—making it highly functional for attorneys, mortgage firms, creative agencies, engineers, therapists, or administrative headquarters. A separate exterior entrance also allows for independent use of each floor. This building stands apart through its premium finish levels and preserved historic character. A complete aesthetic restoration showcases refinished hardwood flooring, warm exposed brick accents, upgraded lighting and fixtures, and thoughtful interior improvements that reflect timeless quality. Natural light floods both levels, and the rear of the property opens toward Laurens’ Back Street Park, offering attractive outdoor views and walkability. With high-profile surrounding businesses, steady foot traffic, ongoing downtown revitalization, and proximity to frequent events hosted on the Laurens Square, the location supports strong visibility and long-term positioning for a tenant with vision. Whether leasing one level or the entire building, the property provides immediate functionality and character-rich appeal—making it an exceptional opportunity within one of the area’s most desirable commercial corridors.

Date on Market:

2025-12-08

Greenville Retail for Lease - Medical

12 Sevier Street - Prime Retail Opportunity Welcome to 12 Sevier Street, a highly visible and versatile retail space located in a free-standing building in the business and retail district of Augusta Road. Located in the sought-after Augusta Road corridor, walking distance to restaurants and shopping. This space offers excellent accessibility, strong traffic exposure, and proximity to Greenville’s most established residential neighborhoods and thriving local businesses. Property Highlights: Walk-in refrigeration storage units convey with lease. (One unit with interior access and One unit with exterior access only) *See images for detail Ample parking - 12 storefront on-site customer parking spaces. Flexible interior layout suitable for a variety of business types. ADA compliant. Surrounded by established retailers, medical offices, restaurants, and mixed-use development Convenient access to Augusta Road, downtown Greenville, and major commuter routes. Signage opportunity on Augusta St. and Sevier St. NNN Lease Zoned RNX-C Whether you’re expanding your business or looking to establish a new presence in one of Greenville’s most desirable commercial districts, 12 Sevier Street offers visibility and convenience.

Date on Market:

2025-12-04

Beaufort Flex for Lease

Property Address: 164 Robert Smalls Pkwy., Beaufort, SC 29902 County: Beaufort Parcel Tax ID: R100-029-000-0166-0000 Lease Rate: $15 psf NNN (Net fees) $1.1 psf. $24,062.50 a/mo. Base rent. $1,764.58 a/mo. NNN Fees Property Size: 47,480+-sf Acres: 1.09 Acres Building Size SF: 19,250+-sf Retail SF: 12,650+-sf including Office SF: 522+-sf Warehouse SF: 6,615+-sf Bathrooms: 2 (Two) ADA Location: Highway 170/ RSP Business Corridor Zoning: T5-UC/RMX (Commercial) Date of Construction: 1976 Date of Renovation: New front brick façade, sealed floor 2025 Property Type: Retail/ Warehouse/ Flex

Date on Market:

2025-11-26

Rock Hill Retail for Lease - York County

• ±1,000 New Housing Units within ±1 Mile Radius • Located Near Winthrop University and University Center (a ±1.3 Million SF ±$200 Million Mixed-Use Development) • Rock Hill is the most populous city in York County and the 5th most populous city in South Carolina. • Located ±20 minutes from Downtown Charlotte with a population of 1.2 Million People • High Visibility and Excellent Traffic Counts

Date on Market:

2025-11-21

Bluffton Flex for Lease

2,655 sf freestanding flex building and 3,000 square foot retail / flex end-unit available for lease. This prominent property has dual access from the Parkway and Scott Way. The 3,000 sf space is immediately in front of the entrance to the property and is wide open, conditioned space, with glass store front, very high ceilings, private restroom and a 12' tall roll up door in the back. The freestanding building is predominantly open with two large offices, two restrooms, glass store front, high ceilings and roll up door. There is parking surrounding the buildings and incredible visibility to the heavy flow of traffic on the Bluffton Parkway. Ideal for just about any retail or service business. Situated on the Bluffton Parkway in the heart of Bluffton's central business district. Bluffton Parkway traffic counts exceed 30,000 VPD. Parallel to Sheridan Park, this location affords access to all of Bluffton, Hilton Head and the surrounding communities within minutes. The property is surrounded by retail, professional office, and light industrial tenants and in close proximity to all of Bluffton's residential communities. 2025 demographics confirm over 48,100 residents within a five mile radius with average household incomes of approximately $137,000. This is a high growth area with limited supply of quality flex / retail units available.

Property Type:

Retail

Date on Market:

2025-12-10

Greer Retail for Lease - Rt 101 Corridor

Reedy River Retail at SVN | Palmetto is pleased to present ±11,900 SF of new construction multi-tenant retail space available at 1963 SC101 in Greer, SC. This development sits on ±3.33 acres in one of the Upstate’s fastest-growing corridors, offering excellent visibility and accessibility with full access on SC-101 and a secondary ingress proposed onto Rogers Bridge Road. The property benefits from strong traffic counts and proximity to national retailers, making it ideal for retail, medical, or office users seeking a prominent location in a high-demand market. The property will be delivered in Warm Grey Shell condition in 2026, featuring HVAC in place and flexible layout options ready for tenant-specific buildout. Key Highlights: Proposed Drive-thru endcap Available Lease Rate: ±$30–35/SF NNN Space Available: ±1,700–11,900 SF Traffic Count: ±27,000 VPD on SC-101 Parking: ±87 spaces (±3.64/1,000 SF)

Date on Market:

2025-11-14

Greenville Industrial for Lease - Western Greenville County

121 Osage Drive is a brand-new industrial/flex space in a high-growth Greenville submarket. The ±25,600 SF metal building is divisible into four suites, each with dedicated storefront entrances and window lines, allowing for customized office build-outs. With eight dock-high doors and four 12’ x 14’ roll-up doors, the facility is designed for efficient logistics and operational flow. Tenants will benefit from 23-foot clear heights, 3-phase power, and a robust 6-inch concrete slab suitable for heavy equipment and storage. Located adjacent to Donaldson Airport and minutes from I-185 and I-85, the site offers excellent access to regional transportation networks and is surrounded by major industrial users including Lockheed Martin and Michelin. The property’s inclusion in an Opportunity Zone may offer additional incentives for qualifying tenants. Whether for distribution, light manufacturing, or flex office use, 121 Osage Drive delivers modern infrastructure and strategic positioning in one of the Southeast’s most dynamic industrial markets.

Date on Market:

2025-11-10

Charleston Retail for Lease - Downtown Charleston

59 Broad Street offers a rare opportunity to lease high-visibility retail/restaurant space in Charleston's iconic Broad Street corridor. Located within a three-story mixed-use building that will soon undergo exciting facade renovations, this suite offers exceptional foot traffic, historic charm, and proximity to some of downtown Charleston’s most sought-after dining, retail, and professional destinations. Ideal for an intimate restaurant, wine bar, coffee shop, etc; owner is willing to provide TIA to assist with the upfit cost for qualified operators. The building will feature an elegant façade with a folding door system so that the entire storefront can be opened up to Broad St on nice days. The interior offers a flexible layout ready to be tailored to a tenant’s specific needs. The first two floors, each just over 1600sf are connected by both elevator and rear stairwell, and allows operates a seamless two-story layout opportunity. Situated on one of the city’s most prestigious and walkable streets, 59 Broad provides a premier address with convenient access to nearby neighborhoods, government buildings, and tourist hubs.

Property Type:

Office

Date on Market:

2025-06-13

Greenville Office for Lease - Greenville CBD

Suite 200 at 245 N. Main Street offers a rare opportunity to lease premier Class A office space in one of Greenville’s most active commercial corridors. Located directly above Sushi Go and across from the Hyatt, the property enjoys exceptional visibility at a high-traffic intersection with dual entrances—one private street-level entry on Main Street with door signage and another on College Street with elevator access. The interior features exposed brick, high ceilings, wood floors, and expansive windows that bring in abundant natural light. The layout includes a large open area for workstations, five private offices or conference rooms, a breakroom/dining area, three restrooms, a phone booth, reception, and multiple storage and IT closets. Architectural details such as exposed wooden beams and window shades add warmth and character to the space. Surrounded by more than 70 restaurants and retailers within a one-mile radius, the location supports both employee convenience and client engagement. Monthly parking options are available nearby, and the walkable environment connects tenants to Greenville’s cultural, dining, and business destinations. This suite is ideal for firms seeking a professional presence with modern finishes and strategic access to the city’s amenities.

Property Type:

Retail

Date on Market:

2025-10-17

Spartanburg Retail for Lease - North Side/Rt 9 Corridor

Positioned along one of Spartanburg’s most traveled corridors, 1103 Asheville Hwy offers a flexible ±8,200 SF footprint ideal for retail or office use. The property has undergone recent renovations, presenting a refreshed façade and updated interiors that support a modern business environment. Its location just minutes from downtown Spartanburg and immediate access to I-85 ensures strong visibility and connectivity for both local and regional traffic. The site features a rear loading dock, enhancing operational efficiency for tenants with light distribution or inventory needs. With frontage on Asheville Highway, the property benefits from high daily traffic counts and proximity to established neighborhoods like Fairview Heights and Hayne Station. The surrounding area includes a mix of residential, educational, and commercial uses, including Wofford College and major employers, contributing to a vibrant customer base. This is a compelling opportunity for businesses seeking a strategic location with flexible space options, strong infrastructure, and access to Spartanburg’s growing economic landscape.

Date on Market:

2025-10-15

Bluffton Retail for Lease

Two suites coming available for lease in this charming class A office building in Bluffton Village. Each suite features a thoughtfully designed, functional layout and high-end finishes. Both are elevator-serviced and include private balconies—perfect for taking a break or meeting with clients outdoors. These suites are an excellent fit for professional office users seeking a prime location near historic downtown Bluffton, with all the character and convenience the area has to offer. Immediately off Highway 46 between the Sam's Club/Walmart development to the north and adjacent to the highly sought after historic downtown area, to the south in Bluffton Village. Bluffton Village is a mixed-use community that includes the Bluffton Post Office and Library, restaurants, retailers, professional office users and residences. This central location provides easy access to anywhere in the market and is less than a 30 minute drive to Savannah. This is an extremely high growth area with strong demand and strong demographics.

Date on Market:

2025-10-13

Ridgeland Retail for Lease

1,000 SF office unit for lease at Riverwalk Commons. The recently remodeled unit is configured with a large open area that could be used as reception and waiting area or showroom plus three offices, a kitchenette and private restroom. Brand new HVAC and water heater. Ideal for a variety of office, retail and service provider uses. Riverwalk Business Park is located on Highway 170, less than 2 miles from the major Highway 278 interchange, proximate to Sun City Hilton Head (with 17,500 residents, age 50+) and two colleges (University of South Carolina/Bluffton and the Technical College of the Lowcountry). This high-traffic and explosive-growth area is centrally located and just minutes from Beaufort, Bluffton, Hilton Head Island and Savannah. Riverwalk Business Park has a broad tenant mix ranging from light industrial to professional office to retail and restaurant tenants. 2024 traffic counts on Highway 170 exceed 39,000 vpd.

Date on Market:

2025-10-09

Anderson Flex for Lease - Anderson County

Palm Plaza Flex offers a rare opportunity to lease versatile flex and warehouse suites in a highly visible and accessible location along North Main Street in Anderson, South Carolina. With ±29,400 vehicles per day and proximity to both Downtown Anderson and Anderson University, this property is ideally positioned for businesses seeking convenience, exposure, and operational efficiency. Tenants benefit from prominent pylon and building signage options, multiple ingress/egress points, and ample parking with ±120 spaces on site. Located just 2.4 miles from Downtown Anderson and 2.5 miles from Anderson University, the property is surrounded by national retailers and local favorites including Whataburger, Dunkin’, QT, and Casa Fuentes. The area’s retail density and traffic counts make Palm Plaza Flex a strategic choice for businesses looking to grow their footprint in a thriving commercial corridor.

Property Type:

Retail

Date on Market:

2025-10-07

Columbia Retail for Lease - CBD

Turnkey restaurant opportunity in the heart of Downtown Columbia. This 1,440 sq. ft. space is ideal for a café, small restaurant, or takeout concept. The space includes a 3-compartment sink, grease trap, and hood system, making it ready for quick setup and operation. Located on Hampton Street, the property offers excellent visibility, walkable access to downtown offices, government buildings, and nearby retail. street parking is available for customers and staff.

Date on Market:

2025-10-07

Anderson Retail for Lease - Anderson County

3014–3016 N. Main Street offers multiple retail suites for lease in one of Anderson’s most established retail corridors. Located along N. Main Street/Clemson Boulevard with ±29,400 vehicles per day, the property provides excellent visibility, pylon and building signage, and ample parking (±120 spaces). Tenants benefit from easy access, multiple ingress/egress points, and proximity to national retailers, restaurants, and banks; just ±2.5 miles from Anderson University and downtown.

Date on Market:

2025-10-07

Charleston Office, Retail for Lease - Downtown Charleston

438 King Street is a three-story, ±10,673 square foot mixed-use building in the heart of Charleston’s historic Upper King Street corridor. Originally built in 1908, the property blends classic architectural character with modern updates. The building features large storefront windows, high ceilings, hardwood floors, and historic detailing throughout. Each floor includes access to outdoor patio or porch space, adding to its charm and usability. The property also includes 18 rare on-site parking spaces. The building is currently undergoing renovations and will be delivered in warm shell condition, offering a flexible canvas for retail, office, restaurant or hospitality. Property is also being offered for sale at $10,000,000.

Date on Market:

2025-10-02

Myrtle Beach Retail for Lease - Downtown Myrtle Beach

Introducing a prime commercial space for lease at 514 Broadway St, Myrtle Beach, SC. This versatile property offers an ideal location for retail or office use, boasting ample square footage for customization, large storefront windows for maximum visibility, and a convenient open layout. With its high foot traffic and proximity to amenities, this space presents an unparalleled opportunity for businesses seeking a vibrant, dynamic environment. Discover endless potential and create a memorable presence in the heart of Myrtle Beach's commercial district. Welcome your customers to a space that embodies the allure of beachfront commerce!

Date on Market:

2025-09-24