204 Storefront Properties for Lease in South Carolina, USA

Pendleton Retail for Lease - Anderson County

This open storefront or office space offers a prime location in the heart of Pendleton Square, the vibrant center of downtown Pendleton, SC. Positioned just minutes from Clemson University, the property benefits from strong local traffic and a steady flow of students, residents, and visitors. The available unit features an open layout with additional storage space, making it ideal for a variety of retail or service-oriented businesses. The surrounding area is home to popular dining and retail destinations, including 1826 Bistro, Blue Heron Restaurant, and The Village Bakery. This space presents an excellent opportunity for retailers seeking a high-visibility presence in a growing market.

Date on Market:

2025-12-17

Laurens Retail for Lease - Laurens County

Located in the heart of Downtown Laurens, SC, this beautifully restored two-story property presents an amazing leasing opportunity for a tenant seeking high visibility, professional appeal, and true character. Formerly constructed as a salon and later converted into a dance studio, the building is perfectly suited for a broad range of uses—whether as an upscale retail concept, a boutique food and beverage operation, or professional office suites. The property features ±2,200 square feet of usable space, with an ideal layout providing flexibility for a full-building lease or floor-by-floor occupancy. The main level offers an open, airy floor plan suitable for retail, service-based businesses, coffee shop, bakery, sushi restaurant, boutique fitness, or similar activations. The upper level includes multiple private rooms—large enough for conference tables or multiple desk setups—making it highly functional for attorneys, mortgage firms, creative agencies, engineers, therapists, or administrative headquarters. A separate exterior entrance also allows for independent use of each floor. This building stands apart through its premium finish levels and preserved historic character. A complete aesthetic restoration showcases refinished hardwood flooring, warm exposed brick accents, upgraded lighting and fixtures, and thoughtful interior improvements that reflect timeless quality. Natural light floods both levels, and the rear of the property opens toward Laurens’ Back Street Park, offering attractive outdoor views and walkability. With high-profile surrounding businesses, steady foot traffic, ongoing downtown revitalization, and proximity to frequent events hosted on the Laurens Square, the location supports strong visibility and long-term positioning for a tenant with vision. Whether leasing one level or the entire building, the property provides immediate functionality and character-rich appeal—making it an exceptional opportunity within one of the area’s most desirable commercial corridors.

Date on Market:

2025-12-08

Lexington Industrial for Lease

Date on Market:

2025-12-04

Bluffton Retail for Lease

Date on Market:

2025-11-25

Summerville Retail for Lease - Outlying Berkeley County

Ready for a business to make it its own - this space is located on the heavily traveled Sigma Drive running through the Nexton community. Suite 102 is directly adjacent to Fu-O BBQ, the Charleston area's first Japanese Yakiniku restaurant (opening Dec 2025) located in Downtown Nexton (DTN Nexton), a mixed use 'Main Street' style development embodying the best New Urbanist ideals. Fu-O BBQ offers a unique blend of Japanese Yakiniku barbecue, sushi, appetizers, and drinks) and provides the perfect setting for variety of occasions and meals ( https://fuorestaurant.com ). DTN Nexton alone is home to several multifamily communities while a full service AC Hotel is expected to open in 2026. This is in addition to the residents in the broader Nexton community with its thousands of houses and multifamily units. Suite 102 offers the opportunity to locate in the prestigious DTN Nexton development next to a new high end restaurant and bar.

Date on Market:

2025-11-21

Rock Hill Retail for Lease - York County

• ±1,000 New Housing Units within ±1 Mile Radius • Located Near Winthrop University and University Center (a ±1.3 Million SF ±$200 Million Mixed-Use Development) • Rock Hill is the most populous city in York County and the 5th most populous city in South Carolina. • Located ±20 minutes from Downtown Charlotte with a population of 1.2 Million People • High Visibility and Excellent Traffic Counts

Date on Market:

2025-11-21

Tega Cay Office/Retail for Lease - York County

Windhaven Village offers new-construction commercial condos in one of South Carolina’s fastest-growing and highest-income markets. Located at 1244 Hubert Graham Way with excellent visibility from Gold Hill Road, these units sit at the entrance of the 329-home Windhaven community and the Tega Cay Peninsula. With flexible PDD zoning for medical, retail, and professional office uses, plus quick access to I-77, Hwy 160, and the Charlotte metro, this location provides strong demographics, steady growth, and outstanding visibility for a wide range of businesses.

Property Type:

Retail

Date on Market:

2025-11-20

Greer Retail for Lease - Rt 101 Corridor

Reedy River Retail at SVN | Palmetto is pleased to present ±11,900 SF of new construction multi-tenant retail space available at 1963 SC101 in Greer, SC. This development sits on ±3.33 acres in one of the Upstate’s fastest-growing corridors, offering excellent visibility and accessibility with full access on SC-101 and a secondary ingress proposed onto Rogers Bridge Road. The property benefits from strong traffic counts and proximity to national retailers, making it ideal for retail, medical, or office users seeking a prominent location in a high-demand market. The property will be delivered in Warm Grey Shell condition in 2026, featuring HVAC in place and flexible layout options ready for tenant-specific buildout. Key Highlights: Proposed Drive-thru endcap Available Lease Rate: ±$30–35/SF NNN Space Available: ±1,700–11,900 SF Traffic Count: ±27,000 VPD on SC-101 Parking: ±87 spaces (±3.64/1,000 SF)

Date on Market:

2025-11-14

Taylors Retail for Lease - Greer/Taylors

Date on Market:

2026-05-01

Greenville Industrial for Lease - Western Greenville County

121 Osage Drive is a brand-new industrial/flex space in a high-growth Greenville submarket. The ±25,600 SF metal building is divisible into four suites, each with dedicated storefront entrances and window lines, allowing for customized office build-outs. With eight dock-high doors and four 12’ x 14’ roll-up doors, the facility is designed for efficient logistics and operational flow. Tenants will benefit from 23-foot clear heights, 3-phase power, and a robust 6-inch concrete slab suitable for heavy equipment and storage. Located adjacent to Donaldson Airport and minutes from I-185 and I-85, the site offers excellent access to regional transportation networks and is surrounded by major industrial users including Lockheed Martin and Michelin. The property’s inclusion in an Opportunity Zone may offer additional incentives for qualifying tenants. Whether for distribution, light manufacturing, or flex office use, 121 Osage Drive delivers modern infrastructure and strategic positioning in one of the Southeast’s most dynamic industrial markets.

Date on Market:

2025-11-10

Columbia Retail for Lease - CBD

Located at 929 Gervais Street, this ±1,710 SF space is situated on the first floor with direct access to Gervais Street. The space has been renovated and features an open floor plan with exposed beams and brick walls, making it an ideal opportunity for retail/office use. This retail space is located in the center of Columbia’s downtown Vista district. The pedestrian-friendly Vista attracts locals and visitors alike with a dynamic mix of restaurants, bars, art galleries and specialty shops. Additionally, the area is convenient to the Central Business District, the SC State House and the University of South Carolina.

Date on Market:

2025-11-07

Greenville Office for Lease - Greenville CBD

Suite 200 at 245 N. Main Street offers a rare opportunity to lease premier Class A office space in one of Greenville’s most active commercial corridors. Located directly above Sushi Go and across from the Hyatt, the property enjoys exceptional visibility at a high-traffic intersection with dual entrances—one private street-level entry on Main Street with door signage and another on College Street with elevator access. The interior features exposed brick, high ceilings, wood floors, and expansive windows that bring in abundant natural light. The layout includes a large open area for workstations, five private offices or conference rooms, a breakroom/dining area, three restrooms, a phone booth, reception, and multiple storage and IT closets. Architectural details such as exposed wooden beams and window shades add warmth and character to the space. Surrounded by more than 70 restaurants and retailers within a one-mile radius, the location supports both employee convenience and client engagement. Monthly parking options are available nearby, and the walkable environment connects tenants to Greenville’s cultural, dining, and business destinations. This suite is ideal for firms seeking a professional presence with modern finishes and strategic access to the city’s amenities.

Property Type:

Retail

Date on Market:

2025-10-17

Spartanburg Retail for Lease - North Side/Rt 9 Corridor

Positioned along one of Spartanburg’s most traveled corridors, 1103 Asheville Hwy offers a flexible ±8,200 SF footprint ideal for retail or office use. The property has undergone recent renovations, presenting a refreshed façade and updated interiors that support a modern business environment. Its location just minutes from downtown Spartanburg and immediate access to I-85 ensures strong visibility and connectivity for both local and regional traffic. The site features a rear loading dock, enhancing operational efficiency for tenants with light distribution or inventory needs. With frontage on Asheville Highway, the property benefits from high daily traffic counts and proximity to established neighborhoods like Fairview Heights and Hayne Station. The surrounding area includes a mix of residential, educational, and commercial uses, including Wofford College and major employers, contributing to a vibrant customer base. This is a compelling opportunity for businesses seeking a strategic location with flexible space options, strong infrastructure, and access to Spartanburg’s growing economic landscape.

Date on Market:

2025-10-15

Myrtle Beach Land for Lease - Downtown Myrtle Beach

100 x 150 Lot on US Hwy 501 with 30,000 cars a day under 45 MPH (According to DOT-Departmment Of Transporation Website ) Less than 1 mile from Walmart, Home Depot, Lowes Hardware and other major retailers And is a major Corridor into Myrtle Beach, SC. This Property is for Lease OR Build To Suit Call Trevor 843-997-0789

Property Subtype:

Agricultural

Date on Market:

2026-03-27

Charleston Office, Retail for Lease - Downtown Charleston

438 King Street is a three-story, ±10,673 square foot mixed-use building in the heart of Charleston’s historic Upper King Street corridor. Originally built in 1908, the property blends classic architectural character with modern updates. The building features large storefront windows, high ceilings, hardwood floors, and historic detailing throughout. Each floor includes access to outdoor patio or porch space, adding to its charm and usability. The property also includes 18 rare on-site parking spaces. The building is currently undergoing renovations and will be delivered in warm shell condition, offering a flexible canvas for retail, office, restaurant or hospitality. Property is also being offered for sale at $10,000,000.

Date on Market:

2025-10-02

West Columbia Office/Retail for Lease - Cayce/West Columbia

Property Type:

Retail

Date on Market:

2025-09-29

Johns Island Retail for Lease - West Islands

3517 Maybank Highway presents a rare opportunity to secure retail space in one of Charleston’s fastest-growing commercial corridors. This ±3.3-acre development on Johns Island offers exceptional visibility and access, with frontage along a high-traffic stretch of Maybank Highway that sees over 19,000 vehicles per day. Zoned under Charleston’s Limited Business Overlay, the site is ideally suited for retail, service, and food & beverage tenants seeking proximity to dense residential growth and future healthcare infrastructure. The property is located just 1.5 miles from the proposed Trident Hospital and is surrounded by multifamily communities, including Middleburg and Hayes Park, ensuring a steady stream of potential customers. The site plan includes a dedicated pad for a quick-service restaurant (QSR) and multiple suites ranging from 1,500 to 4,500 square feet, with tenant improvement allowances available. Co-tenancy includes a mix of retail, café, and supermarket uses, creating a vibrant and complementary tenant mix. Demographics within a 20-minute drive show a population of nearly 200,000, with an average household income of $129,940 and a median income of $94,000, underscoring the area’s strong consumer base. The site also benefits from 89 on-site parking spaces and a conceptual layout that supports flexible configurations for tenants. This is a prime opportunity for retailers and service providers to establish a foothold in a high-growth, high-income market with long-term upside.

Date on Market:

2025-10-29

Irmo Retail for Lease - Dutch Fork/Irmo

This 1,904-square-foot office and retail space is located in the heart of Irmo’s thriving Broad River Rd retail corridor with traffic counts of 14,600 vehicles per day. The space sits within the Publix shopping center, offering high visibility and steady foot traffic from surrounding national and local retailers. The property includes a flexible floor plan, making it ideal for professional services, boutique retail or customer-facing businesses. It is conveniently located near Dutch Fork schools and just minutes from Interstate 26, providing easy access for both customers and employees.

Date on Market:

2025-09-24

Clinton Retail for Lease - Laurens County

Reedy River Retail at SVN Palmetto is pleased to present a proposal for this property which is a rare opportunity located at the highly visible corner of Main Street and Musgrove Street, this ±2,200 SF retail space offers one of the best positions in downtown Clinton. Formerly home to a men’s clothing shop for many years and cigar lounge, the space is now vacant and ready for your new concept. With daily traffic counts of ±12,000 VPD on Carolina Avenue and ±10,000 VPD on Broad Street, this location delivers excellent exposure and steady customer flow. The property sits directly across from a public parking lot and the community stage, home to popular events like Rhythm on the Rails, which draws large crowds to the heart of downtown. Surrounded by a mix of national, regional, and local retailers including McDonald’s, True Value Hardware, Taco Bell/KFC, and numerous boutique shops, the property also benefits from nearby residential density, with apartments located directly behind the building. Major area traffic drivers include Presbyterian College, local dining establishments, and a vibrant cluster of downtown businesses. This versatile, blank space is ideal for an ice cream shop, coffee shop, boutique clothing store, or nearly any retailer seeking a flagship downtown Clinton presence. Situated along Clinton’s main retail artery, this is where locals come to shop, dine, and gather making it a prime opportunity for your next venture.

Date on Market:

2025-09-12

Travelers Rest Retail for Lease

Reedy River Retail at SVN Palmetto is pleased to present the opportunity to lease within this new construction retail strip center located on State Park Road in Travelers Rest, SC, just off HWY 25 (±28,200 VPD). Travelers Rest is a rapidly growing suburb of the Greenville, SC MSA with demand for more retail, coupled with a residential expansion and Furman University (±2,500 students). Surrounded by national retailers, such as WalMart, Chickfila, Starbucks and Chipotle this center is prepared for additional national, regional and local retailers.

Date on Market:

2025-09-10

Duncan Retail for Lease - Rt 290 Corridor

Reedy River Retail at SVN Palmetto is pleased to present an opportunity to lease space within Phase III of this HWY 290 (±37,500 VPD) retail development in Duncan, SC. The commercial and industrial growth of the Duncan and HWY 290 market continues to surpass expectations. This parcel is one of the last parcels that will have the ability for new retail development (unless future infill sites become available). Surrounded by high paying distribution & manufacturing professions, residential growth, I-85 and a Greenville Tech College campus, this retail opportunity is perfectly situated to capture it all.

Date on Market:

2026-01-26

Columbia Office/Medical for Lease - CBD

Property Type:

Retail

Date on Market:

2025-08-27

Ridgeland Office/Retail for Lease

The Terrace at Okatie Crossings is a brand new development with retail, restaurant, office & medical professional users. The buildings are directly on highway 170 with excellent visibility and close to Highway 278 Interchange Excellent location situated between Bluffton and Beaufort and surrounded by Sun City. The immediate area is experiencing unprecedented growth in both residential and commercial development. Other tenants include; Papa Murphy's Pizza, iCryo Recovery & Wellness, Hawg's Golf Carts & ATV's, Yamato Asian Grill, Sassy Nails, Marsh Point Dentistry, Heritage Pharmacy & Ochsner Novant Health.

Property Type:

Retail

Date on Market:

2025-08-20

Greenville Office/Retail for Lease - West End

Position your business in the heart of Greenville’s thriving West End at 23 Falls Park Drive. This beautifully renovated 9,000 SF property offers 5,000 SF of flexible office or retail space available for lease starting September 1, 2025. The open-plan layout is ideal for modern workspaces or customer-facing retail environments. Just one block from South Main Street and steps from Falls Park, this location provides excellent visibility, walkability, and access to downtown’s bustling energy.

Property Type:

Retail

Date on Market:

2025-07-10