198 Storefront Properties for Lease in South Carolina, USA

Aiken Medical, Retail for Lease - Outlying Aiken County

Centre South, a diversified and established shopping center outside of Augusta, Georgia, now invites businesses to join its coactive mix of thriving tenants. Food Lion and USPS are currently the main traffic anchors of Centre South, complemented by a handful of financial services, salons, Happy Spirits, Aiken Antiques, and Habanero’s Mexican Grill. Centre South’s consumer base is soon to be invigorated and broadened by the opening of Back Nine Golf, which is currently building out its space. The indoor golf simulator chain is rapidly expanding nationwide, and this store comes after the brilliant success of its location 30 minutes away in Augusta. The landlord is open to various types of businesses, including daycares, specialty gyms, lifestyle and entertainment hubs, and more. Additionally, tenant improvement allowances and build-to-suit services are negotiable. Aiken, South Carolina, is a respectable retail submarket within the Greater Augusta metro. While the home of the Masters Tournament anchors much of the commercial landscape, outlying communities contribute to business success. Aiken’s average retail vacancy rate, which was reportedly half a percentage point lower than the broader market’s figure in Q4 2025. From a demographic perspective, the area’s full-time population has incomes well above the national average, and growth projections indicate a significant increase in households over the coming years.

Date on Market:

2026-03-16

Greenville Retail for Lease - Pelham/I-85

Join a thriving retail center with an exceptional location in Greenville, South Carolina, at Pelham Hills, offering a modern, in-line retail suite for immediate occupancy at 3712 Pelham Road. Comprising a total of 1,250 square feet with desirable features, this prime opportunity presents the perfect choice for a wide range of storefront retailers, medical/wellness operations, fitness facilities, and service-based businesses eager to establish or expand their presence in a dynamic commercial setting. The suite features a fully windowed storefront with awnings, creating an inviting entrance and prominent signage possibilities. Positioned along one of the shopping center’s main drive lanes, the space benefits from substantial exposure to cross-traffic. New occupants will join a strong tenant mix, including a nail salon, a Japanese restaurant, and Massage Envy, all of which contribute to consistent, diversified customer flow. To support this elevated activity, 3712 Pelham Road provides ample on-site parking, ensuring convenience for both tenants and shoppers. Pelham Hills situates businesses within a dynamic retail hub positioned just off Interstate 85, the main commuter and leisure artery connecting Greenville and Spartanburg. More than 24,000 daily vehicles pass by the location on Pelham Road, delivering premier brand exposure for growing businesses. The surrounding area draws steady customer activity with a wealth of national brands, including Walmart Supercenter, Lowe’s, Pet Supermarket, CVS, Starbucks, Chick-fil-A, Chipotle, Whataburger, and more. In addition, the location offers proximity to key demand drivers, including Greenville-Spartanburg International Airport, the BMW Group Plant, and Thornblade Country Club, all within a short 10-minute drive. Supporting growth and prosperity for retailers, Greenville delivers a valuable demographic profile when looking within just 5 miles of Pelham Hills. The area is home to a growing population of more than 146,000, which has increased by 6% since 2020. Locals earn an average household income of more than $119,000, resulting in impressive consumer spending of more than $2 billion annually. This affluent and expanding customer base provides a solid foundation for businesses to prosper and achieve long-term success at Pelham Hills.

Date on Market:

2026-03-09

Bluffton Office/Retail for Lease

Elevate your business presence in the heart of Downtown Bluffton at the highly coveted Promenade. This stunning, updated commercial condo delivers exceptional visibility, strong daily foot traffic, and unmatched exposure to both locals and the steady flow of Lowcountry visitors. Surrounded by Bluffton’s most popular boutiques, art galleries, award-winning restaurants, and vibrant year-round events, this premier location places your business at the center of one of the area’s most energetic and desirable commercial districts. The prominent property positioning offers maximum storefront exposure and creates the perfect setting for an ince cream shop, retail, office, gallery, wellness, or specialty concepts seeking a polished and professional downtown presence. With Bluffton continuing to experience explosive growth, a Promenade address remains the premier location for commercial success in the Lowcountry. Rarely do opportunities become available in this high-demand destination. This lease is offered as a NNN lease. Estimated CAM, taxes, and insurance expenses are approximately $1,261 per month and are in addition to the base rental rate.

Property Type:

Retail

Date on Market:

2026-05-07

Hilton Head Island Retail for Lease

1,013 SF retail space coming available in one of Hilton Head Island's premier shopping centers. Main Street Village has become a favorite place to dine and shop with some of the island's most popular restaurants including Frankie Bones, Wise Guys, and Cactus Street Cantina. The center is anchored by a very busy Harris Teeter grocery store with a Starbucks inside. Customers enjoy meandering among the the unique mix of retailers including J McLaughlin and the Milk Shake Factory, clothing and home goods retailers, a gift shop, a variety of service providers and so much more. Situated on William Hilton Parkway (Hwy 278) and Main Street, on the north end of the island, immediately outside the main gate to Hilton Head Plantation, the island's largest residential community and directly across the street from Indigo Run, another significant residential development. The property is easily accessible with multiple access points on Main Street and prominent visibility on Highway 278. Main Street Village is located in close proximity to Hilton Head schools, Hilton Head hospital and is surrounded by retail, professional office and residential developments Strong demographics including a population of approximately 35,000 in a five-mile radius, with average household incomes exceeding $160,000.

Date on Market:

2026-05-04

Charleston Office, Retail for Lease - Downtown Charleston

Date on Market:

2026-05-01

Summerville Retail for Lease - Dorchester County

Date on Market:

2026-04-30

Bluffton Retail for Lease

1,500 square feet of prime retail space available for lease in the Target Shopping Center in Bluffton, SC. Formerly occupied by a custom home builder the suite is very nicely upgraded and includes open retail space in the front, 3 offices/rooms along the hallway toward the rear, storage area, and bathroom. There is plenty of plumbing for additional sinks as well as a washer/dryer connection. The rear of the suite has excellent access for deliveries via the back door and a virtually private driveway for access. Anchor Tenants in the property include Target, Dick's Sporting Goods, Staples, and Starbucks along with a multitude of restaurants, retailers, and professional office/medical users. Located in the highly trafficked Target Shopping Center in the heart of Bluffton, SC with easy access to Hilton Head Island and all surrounding areas. This retail complex fronts directly on Highway 278 with arterial access from Highway 46 with anchor Tenants such as Target, Dick's Sporting Goods, Staples, Starbucks, and more.

Date on Market:

2026-04-29

Summerville Office/Retail for Lease - Outlying Berkeley County

UPTOWN Carnes Crossroads is a high-performing mixed-use commercial development located in one of the fastest-growing areas of the Charleston region. The project offers a strong blend of retail, restaurant, medical, office, and service-oriented tenants, creating consistent daily traffic and cross-shopping opportunities. The walkable layout, anchored by the UPTOWN Green and regular community programming, drives steady foot traffic throughout the day and evening, providing tenants with built-in visibility and customer flow. The development is surrounded by rapidly expanding residential neighborhoods and is positioned along major corridors including Highway 17A and Highway 176, offering excellent accessibility and exposure. Tenants benefit from a well-established environment with a proven track record of leasing success, strong co-tenancy, and a growing customer base. UPTOWN Carnes Crossroads is an ideal location for businesses seeking visibility, accessibility, and immediate integration into an active commercial setting.

Property Type:

Retail

Date on Market:

2026-04-28

Ladson Flex for Lease - North Charleston

Highly functional and visually appealing 6,100 SF warehouse/showroom building for lease located along the Highway 78 corridor in the Ladson area. The property features approximately 4,000 SF of warehouse space with two garage doors, restrooms, and complemented by a beautiful showroom and office area with floor-to-ceiling glass storefront, providing natural light and visibility for customer-facing operations. The office layout includes a reception area, private offices, and restrooms. Ideal for a variety of users. NNN fees are estimated at $3.35 psf. Situated on ±1 acre, the site includes a ±0.5-acre fenced laydown yard, ideal for outdoor storage, equipment, or fleet use. Conveniently located just minutes from Interstate 26, the property provides easy access to the greater Charleston market and surrounding industrial hubs.

Date on Market:

2026-04-27

Rock Hill Retail for Lease - York County

The Park at UC offers retail and creative office space within one of the most active mixed-use environments in the Charlotte MSA. Located in Rock Hill’s University Center, a $250 million redevelopment of a former industrial site into a 1.9 million square foot live-work-play district, the property sits at the center of daily activity driven by residential density, hospitality, and institutional presence. The project benefits from the neighboring arenas, Rock Hill Sports & Event Center and the new Bleachery Fieldhouse arena, and proximity to Winthrop University. This creates a consistent flow of students, residents, and regional visitors. This convergence of demand supports a retail environment best suited for experiential, creative office, and service-oriented users seeking sustained foot traffic within a walkable, destination-oriented setting.

Date on Market:

2026-04-24

Mount Pleasant Retail for Lease - East Islands/Mt Pleasant

Oswald Cooke & Associates is proud to present a newly renovated retail opportunity in the heart of Mount Pleasant. The property offers a total of 8,186 square feet, including a highly desirable drive-thru lane with double drive thru lane potential. Suite B comprises 3,850 square feet, while Suite C offers 4,336 square feet. The building underwent a complete renovation in 2020 and is ideally positioned as an outparcel to Mount Pleasant Towne Centre—the premier retail destination within the submarket. This location benefits from strong regional draw, serving not only Mount Pleasant but also the surrounding communities of Awendaw, Isle of Palms, and Sullivan’s Island, all of which rely on this corridor as a primary shopping hub. Situated at the signalized intersection of U.S. Highway 17 (45,300 VPD) and Market Center Boulevard, the site offers exceptional visibility and access. It is located directly across from Indigo Square, a vibrant mixed-use development featuring hotel, multifamily, and retail components. The immediate trade area is anchored by a strong lineup of national retailers and restaurants, including Arhaus, Ballard Designs, Old Navy, Gap, Barnes & Noble, Lowe’s, CAVA, Starbucks, First Watch, Walgreens, and Chase Bank, among many others—creating a dynamic and high-traffic retail environment.

Date on Market:

2026-04-23

Bluffton Retail for Lease

Prime retail/flex end-cap available for sublease along Bluffton Parkway. This 6,100 SF space combines two units and offers exceptional visibility, very high ceilings, and abundant natural light from windows on two sides. The layout is primarily open, and includes three restrooms and a roll-up door, providing flexibility for a wide range of uses. An outdoor patio area enhances the space, while dual access from Bluffton Parkway and Scott Way ensures convenience. Ample parking surrounds the building. Ideal for retail, restaurant, or service-oriented businesses. Sublease term runs through April 2029 (approximately three years remaining). Situated on the Bluffton Parkway in the heart of Bluffton's central business district. Bluffton Parkway traffic counts exceed 30,000 VPD. Parallel to Sheridan Park, this location affords access to all of Bluffton, Hilton Head and the surrounding communities within minutes. The property is surrounded by retail, professional office, and light industrial tenants and in close proximity to all of Bluffton's residential communities. 2025 demographics confirm over 48,100 residents within a five mile radius with average household incomes of approximately $137,000. This is a high growth area with limited supply of quality retail / flex units available.

Date on Market:

2026-04-23

Blythewood Retail for Lease - Northeast Columbia

The plaza is located at the same I-77 exit as the new Scout Motors manufacturing facility, which is expected to spur major economic growth and elevate consumer demand in the area. Existing co-tenancy with high-traffic tenants such as Dollar General, Papa John’s, FedEx, and medical offices enhances the overall draw of the center. Tenants enjoy ample on-site parking with 60 available spaces and storefront signage opportunities. With infrastructure improvements and regional development underway, this space offers businesses a foothold in an established retail corridor poised for significant future expansion.

Date on Market:

2026-05-07

Tega Cay Retail for Lease - York County

• Located off Interstate 77, Exit 85 and US Highway 160 within The Shoppes at Stonecrest, a Retail Component of Stonecrest Village. • Excellent Visibility and Strong Residential Support in a Walkable, Amenity-Rich Environment. • Stonecrest Village is a ±160-Acre, Rapidly Growing Mixed-Use Development Surrounded by Approximately 1,500 Homes. • Located Near Tenants Including Walmart Supercenter, Circle K, Taco Bell, Hoof & Barrel, Discount Tire, First Horizon Bank, Wellmore of Tega Cay, The Learning Experience, and Baxter Veterinary Clinic.

Date on Market:

2026-04-14

Greenville Retail for Lease - West Side Greenville

Great location across from Cherrydale Point.

Date on Market:

2026-04-14

Greer Retail for Lease - Greer/Taylors

Great Retail location in the Heart of Downtown Greer! Beautiful building!

Date on Market:

2026-04-12

Columbia Retail for Lease - North Columbia

Unit A is a 1,013 sq. ft. retail space located within a well-positioned strip center on North Main Street in Columbia, South Carolina. The property offers excellent visibility and is conveniently situated approximately 10 minutes from downtown Columbia, with easy access to a nearby freeway interchange. The space features a recently renovated interior, including new flooring and an updated HVAC system with approximately three years remaining on the mechanical warranty. The open floor plan provides a flexible layout, making it ideal for a variety of retail or service-based uses. Offered under a triple net (NNN) lease structure, the space allows tenants to customize their build-out to suit their specific business need

Date on Market:

2026-04-07

Charleston Retail for Lease - Downtown Charleston

345 King Street is a well-appointed two-story building south of Calhoun with a nice rooftop area on the 2nd floor. Both first and second floors are well laid out and ideal for a retailer.

Date on Market:

2026-04-02

Gray Court Office/Retail for Lease - Laurens County

Property Type:

Specialty

Date on Market:

2026-03-26

Greenville Retail for Lease - Pelham Road

The property at 7 Brendan Way in Greenville, South Carolina, is a multi-tenant retail and office building located in the Eastside submarket. It was originally built in 1981 and underwent renovations in 2014. The building offers surface parking and is zoned C-2. It is situated near major roadways, including Interstate 385, and is approximately 8.8 miles from Greenville-Spartanburg International Airport and 5.7 miles from the Greenville Amtrak Station. Surrounding uses include retail, dining, and service businesses.

Date on Market:

2026-04-22

Greenwood Retail for Lease

Retail space for lease at Greenwood Plaza located at 222-254 Bypass 72 NW in Greenwood, South Carolina. This established Greenwood retail shopping center sits along the highly traveled Highway 72 Bypass retail corridor, one of the city’s primary commercial routes with approximately 23,000 vehicles per day. The property currently offers 3,200 to 5,400 square feet of retail space for lease, making it ideal for retail, restaurant, medical, office, or service users seeking strong visibility in the Greenwood market. Select suites offer flexible layouts suitable for a variety of businesses looking to benefit from the area’s established consumer base. Greenwood Plaza shopping center features a strong tenant mix that includes national and regional retailers, helping drive consistent customer traffic throughout the day. The center provides excellent visibility, ample surface parking, convenient access, and prominent storefront signage opportunities for tenants. Located near Lander University and surrounded by dense residential neighborhoods and major retail destinations, the property benefits from a steady flow of local and regional shoppers. Businesses at Greenwood Plaza gain exposure to customers traveling the Highway 72 Bypass retail corridor, one of the busiest commercial areas in Greenwood. This location presents an outstanding opportunity for businesses seeking high-visibility retail space in Greenwood SC within an established shopping center environment.

Date on Market:

2024-12-04

Columbia Retail for Lease - CBD

±900 SF Retail/Office Suite for Lease Located in the Heart of Soda City Market Zoning: DAC - Downtown Activity Center Two Designated Parking Spots Behind the Property

Date on Market:

2026-03-12

Charleston Office/Retail for Lease - West Ashley

Prime retail space located on Savannah Highway in Charleston’s West Ashley submarket, offering exceptional visibility and frontage along one of the city’s most traveled corridors. This property is positioned inside I-526 and benefits from strong traffic counts and proximity to a planned convention center, enhancing long-term demand. The available 4,800 SF space is part of a 6,000 SF building and features a flexible layout suitable for retail or office use. The site includes surface parking for 12 vehicles and signage opportunities to maximize exposure. Located within the DuWap Overlay District, the property provides convenient access to major roadways, public transportation, and Charleston International Airport, just 16 minutes away.

Property Type:

Retail

Date on Market:

2026-03-10

Greer Retail for Lease - Upper Spartanburg County

Tenant pays Utilities for rented space only, no CAM fees

Date on Market:

2026-03-07