29 Warehouses for Lease in Kearny Mesa, San Diego, CA, USA

San Diego Flex for Lease - Kearny Mesa

Exceptional opportunity to lease a highly improved freestanding building of 56,159 square feet in the most strategic location in all of San Diego, located in the heart of Kearny Mesa. Providing exceptional freeway and surface street access, this facility logistically from a business and quality of life perspective, is a home run. 4650 Overland Avenue is perfect for any flex, R&D, life science, lab, medical, and precision manufacturing applications. The interior has a mix of lab space, clean rooms, conference, private offices, open-plan bullpen areas, kitchen/lunchroom/lounge section, patios, and skylights. The warehouse space has numerous dock loading doors, great clear height, locker rooms, and showers. With a very distinctive architecture, this property creates an exceptional client and employee experience and energy that is unique and in a class of its own. All of this is supported by a robust HVAC and distribution system, multiple floor drains, waterlines, fully sprinklered areas, a backup diesel generator, a significant gas and air network, and a 4,000-amp, 277/480-volt power capacity, which can be cost-effectively expanded due to prior infrastructure preparation. The entire property can easily be enclosed, and a conduit is in place to install security gates. 4650 Overland Avenue is situated within the Spectrum Center, a very walkable and upscale neighborhood with a significant array of amenities within minutes. Multiple throughfares are proximate to the facility, including Interstates 15, 8, and 805, as well as the 163 and 52 freeways, which route into San Diego within a five-minute drive and extend into the Inland Empire and Los Angeles in under two hours. For easy connections to international and domestic markets, the San Diego International Airport is only 9.2 miles away. Don't miss out on a one-of-a-kind facility that can serve any manufacturing or distribution business long into the future, offering critical in-place infrastructure and flexible interior configurations that allow a business to scale and grow with its evolving operational requirements. This opportunity is perfect for an owner/user who is looking to expand their operation into a showstopping space.

Date on Market:

2025-05-01

San Diego Industrial for Lease - Kearny Mesa

Date on Market:

2026-05-15

San Diego Industrial for Lease - Kearny Mesa

Industrial space with office space and two bathrooms (2073SF) total. 8ft Rollup door and 16ft ceiling height in main industrial space. The office portion is approximately 300 SF with two bathrooms located in the attached industrial space. Parking is open parking—small storage area upstairs above the main space. The owner will pay cooperating broker commissions.

Date on Market:

2025-09-17

San Diego Flex for Lease - Kearny Mesa

Zoning: RMX-2 *Tenant to verify use complies for zoning Accessibility: Easy access to Freeways 163, 15, 805, & 52

Date on Market:

2026-04-06

San Diego Industrial for Lease - Kearny Mesa

Date on Market:

2026-03-09

San Diego Industrial for Lease - Kearny Mesa

Date on Market:

2026-03-05

San Diego Industrial for Lease - Kearny Mesa

We are excited to offer two prime commercial spaces available for rent in the highly sought-after area of Kearny Mesa. Front Building: Size: 6,765 sq. ft. The entire front building is available, providing ample space for a variety of commercial uses. With its prominent street frontage, it offers excellent visibility and accessibility for customers. Rear Building - Warehouse: Size: 1,980 sq. ft. A warehouse space in the rear building is available, ideal for distribution, storage, or industrial use. Space comes with 6 assigned parking spot in gated parking lot. For more details on each unit, please contact us to schedule a viewing. Don’t miss this opportunity to establish your business in a prime location in Kearny Mesa!

Date on Market:

2026-01-27

San Diego Industrial for Lease - Kearny Mesa

Conveniently located near major freeways including I-15, I-805, and SR-52, the site ensures seamless connectivity to the greater San Diego region. Surrounding amenities include retail, dining, and hospitality options, creating a vibrant business ecosystem. Nearby landmarks such as Montgomery Field Airport and USMC Air Station Miramar further enhance logistical advantages.

Date on Market:

2025-12-04

San Diego Industrial for Lease - Kearny Mesa

Located in the heart of Kearny Mesa, Suite B at 5038 Ruffner Street offers a highly functional ±3,122 SF industrial space ideal for businesses seeking a strategic San Diego location. The suite features a balanced layout with approximately 25% office and 75% warehouse, providing flexibility for operations, storage, and administrative needs. With grade-level loading and 13’–15’ clear heights, the warehouse is optimized for efficient logistics and light industrial use. The property boasts strong visibility with frontage on Ruffner Street and is situated just off Clairemont Mesa Boulevard, placing it within walking distance of retail amenities and minutes from major transportation corridors including I-805, Highway 52, and Highway 163. Drive-around truck access and available gas service further enhance operational convenience.

Date on Market:

2026-05-28

San Diego Flex for Lease - Kearny Mesa

Property Type:

Industrial

Date on Market:

2025-08-13

San Diego Industrial for Lease - Kearny Mesa

An approximate 11,582 SF industrial/flex unit located within a larger approximate 33,000 SF building. Part of the Kearny Mesa Complex Business Park. Subject unit buildout includes 25% Office / 75% Warehouse. Two (2) Grade level loading doors. Ownership recently completely renovating the entire premises to move-in ready condition. New carpet, paint, and lighting throughout office and warehouse areas. Lit'l Pepper Deli located within walking distance.

Date on Market:

2025-05-27

San Diego Flex for Lease - Kearny Mesa

Multi-Tenant Industrial/Flex Park totaling 210,916 SF

Property Type:

Industrial

Date on Market:

2025-04-25

San Diego Industrial for Lease - Kearny Mesa

Multi-tenant Industrial park in the heart of Kearny Mesa

Date on Market:

2026-01-05

San Diego Office for Lease - Kearny Mesa

Collins Business Park is one of the highest quality R&D parks in Central San Diego County. Conveniently located on the I-15 corridor of Kearny Mesa, the project offers unsurpassed freeway access along with a corporate identity

Property Type:

Flex

Date on Market:

2026-04-30

San Diego Industrial for Lease - Kearny Mesa

High image business park. 1 block South of Highway 52 via Ruffin Road.

Date on Market:

2026-03-26

San Diego Office, Flex for Lease - Kearny Mesa

The Ronson Court Business Park is a 70,808-square-foot project spread across five high-quality buildings. The park is locally managed and has excellent freeway access to I-15, Hwy-163, and Hwy-52

Date on Market:

2026-02-04

San Diego Flex, Industrial for Lease - Kearny Mesa

Date on Market:

2026-04-22

San Diego Flex, Industrial for Lease - Kearny Mesa

Date on Market:

2026-05-20

San Diego Multiple Space Uses for Lease - Kearny Mesa

• Location, Location, Location (Heart of Kearny Mesa) • Excellent Freeway Access (Interstate 805 & 15 and Highways 163 & 52) • Flexible Layouts, Various Office and Warehouse Combinations • Institutional Ownership with Responsive, Local, On-Site Management • Amenities On-Site or Within Walking Distance • Street Frontage Locations Provide Excellent Exposure for Identity and Signage

Date on Market:

2026-04-02

San Diego Industrial for Lease - Kearny Mesa

Date on Market:

2026-01-20

San Diego Flex for Lease - Kearny Mesa

Kearny Mesa Landing is an eight building flex project totaling 155,691 square feet of R&D/Industrial space.

Date on Market:

2026-04-15

San Diego Industrial for Lease - Kearny Mesa

Kearny Mesa Industrial Park is situated close to I-805 and Hwy 163 in an outstanding central San Diego location. It features an on site deli, 14' to 20' clear height and dock/grade level doors.

Date on Market:

2025-10-30

San Diego Flex, Industrial for Lease - Kearny Mesa

Multitenant Retail and Industrial Park located just West of the 163 on signalized intersection. Frontage space available with overhead door loading and dedicated warehouse available. Front and rear loading warehouse suites available in addition to freestanding warehouse buildings with private yards and loading docks/truckwells. Ownership can accommodate wide range of use types. 100,000+ SF Multitenant park featuring overflow parking and multiple opportunities for signage.

Date on Market:

2026-05-21

San Diego Industrial for Lease - Kearny Mesa

Newly constructed industrial building efficiently designed to accommodate a variety of users and provide maximum function, flexibility and prominent corporate identity. LEED Gold/ESG Features: • HVLS fans • Touchless plumbing fixtures • Electrical outlets at each dock high loading door • Negative ion generators & UV lights on office HVAC system • Thermostats & timers on warehouse exhaust fans for night flushing of warehouse • LED lighting throughout with motion sensors • Water bottle filling station • EV chargers • TPO roofing with high solar reflectivity value • 100% site paving in concrete • Outdoor break area • Native drought tolerant landscape all on drip system • Shower in office Solar: PV DC System Size: 200 kWPV AC System Size: 160 kW Estimated Annual Production: 310,000 kWh Rexford will provide the solar production energy at 5% reduced rate compared to the utility energy. Rexford will also provide all the capital & oversight to design, install & maintain the system at no additional cost to the tenant.

Date on Market:

2026-04-17