47 Life Science Properties for Lease in Colorado, USA

Greenwood Village Office for Lease

BE A PART OF SOMETHING BOLD Colorado Health & Tech Centers is bringing first-to-market space solutions for businesses that thrive in a fast-paced life science community. CHTC-Greenwood Village at 5800 S Quebec Street is the debut location of this cutting-edge initiative, with more coming soon to further invigorate Denver’s life science industry. BUILD-TO-SUIT SOLUTIONS Tenants will see their innovative dreams become a reality as Colorado Health & Tech Centers can provide turnkey workspaces equipped with state-of-the-art features. Spaces range from 1,000 to over 100,000 square feet and are offered at highly aggressive rates, roughly 50% less than competitors. Founder Dr. Afshin Safavi and CHTC's team of experts bring build-to-suit business space solutions to innovators who want to get to market faster. Whether a workspace environment is intended for quantum tech, aerospace research, AI, tech, biotech, biomanufacturing, medical office, lab work, company HQ, or satellite office, the team at CHTC will be there to find the perfect solution. WHERE INNOVATION COMES TO THRIVE CHTC-Greenwood Village seeks to form a synergy with its community of advanced organizations and Colorado’s talented professionals. An entire floor will be dedicated to biotech incubator space for growing companies and start-ups to get to work immediately with a low barrier of entry. Lessees will be able to work with those incubators and other occupants to coactively collaborate on the newest scientific advancements. CHTC aims to foster partnerships with regional universities to keep talent in Colorado, and its founder is already leveraging his deep roots in the medical community to develop a pipeline of the state’s top graduates. LIFE SCIENCE + LIFESTYLE LOCATION 5800 S Quebec Street is virtually adjacent to the Denver Tech Center, a primary professional hub known for its major companies largely specializing in technology and medical industries. As a result, well-educated households proliferate the area and 64% of the residents within a 3-mile radius have attained a bachelor's degree or higher. This advantageous address provides quick connections via Interstate 25, allowing drivers to reach as far as Downtown Denver, DIA, Boulder, Lakewood, and more in 20 to 40 minutes. Public transit users can walk to a light rail stop, and the immediate area is replete with lifestyle amenities. The Landmark, Target, REI, Sprouts Farmers Market, Fiddlers Green Amphitheater, multiple fitness options, over a dozen hotels, 100+ restaurants, and much more are all within 2 miles of the site. Discover this catalyst to propel business forward and get innovations off the ground at CHTC-Greenwood Village today.

Date on Market:

2025-04-02

Watkins Coworking for Lease - Outlying Arapahoe County

Property Type:

Office

Date on Market:

2025-11-10

Greenwood Village Office for Lease

6080 Greenwood Plaza Blvd is an 8,771-square-foot office and lab building located in the heart of Greenwood Village. The property features well-finished office space with a dedicated 553-square-foot lab and clean room. Built in 1979 and zoned PUD within The Commons, the building offers flexible suite configurations and quality improvements suitable for a variety of professional, medical, or technical uses. The location provides excellent access to I-25, public transportation, and surrounding retail and dining amenities.

Date on Market:

2025-10-28

Fort Collins Office for Lease - Fort Collins/Loveland

Innosphere is the dynamic 3 Story LEED Platinum Innovation Center. Currently available are 3 Class A Office units available for lease. Ranging from 390 +/- square feet to 550+ square feet these are ideal as its more than just an exceptional space, it immerses you in a thriving entrepreneurial ecosystem. Innosphere offers state of the art facilities and amenities and a vibrant community just steps from Old Town. Offering free business educational programs, pushing the boundaries of bio-tech, research and more. Located on the north end of Old Town in Fort Collins, this building is within walking distance of New Belgium Brewing and provides easy access to Poudre River bike trail system. These suites offer access to reserve, free of charge, large and small meeting spaces with all A/V equipment. Enjoy a quick break or meeting on the large outdoor plaza and patio areas. Bike Storage, Ample parking, Bathroom Showers and lockers and did we mention the Espresso Machines free of charge? Call to visit this exciting opportunity today!

Date on Market:

2025-10-24

Colorado Springs Office for Lease - Southeast

980 Technology Court offers a rare opportunity for large-block users to secure high-quality office space in the established Patriot Park business park. With ±20,170 SF available in a single, efficient floor plan, the property is ideally suited for defense contractors, government users, call centers, and large-scale professional service operations seeking a secure and scalable environment. Key features include ample surface parking (3.8/1,000 SF ratio), updated office finishes, and strong infrastructure to support high-density or specialized uses. Located just minutes from Peterson Space Force Base, Colorado Springs Airport, and Powers Boulevard, the site provides excellent connectivity to both workforce and regional amenities. Surrounded by leading aerospace, technology, and defense firms, 980 Technology Court positions tenants at the center of Colorado Springs’ growing innovation corridor. With a strong landlord and competitive economics, this property delivers the size, efficiency, and location rarely available in today’s market.

Date on Market:

2025-10-20

Lakewood Industrial for Lease - West Denver

Located in the heart of Lakewood, Colorado, 810 Quail Street offers a prime position within the vibrant West Denver market. This area is known for its convenient access to major thoroughfares like 6th Avenue and Union Boulevard, making it ideal for both commuters and businesses. Just minutes away is the Belmar shopping and dining district, a popular destination for retail, restaurants, and entertainment. Nature lovers will appreciate nearby Bellows Park, a scenic green space with whimsical sculptures and a trail along Lakewood Gulch, as well as Quail Street Park, a newer neighborhood park featuring inclusive playground equipment and open space for recreation.

Date on Market:

2025-10-12

Evergreen Flex for Lease - Clear Creek County

Date on Market:

2025-09-22

Arvada Industrial for Lease - West Denver

Discover a rare leasing opportunity in Arvada with two spaces available individually or together, including a 12,615 SF stand-alone light industrial building and a 1.5-acre fenced and gated outdoor storage yard. Perfectly located off Highway 72 between Indiana Street and Highway 93, the property offers I-2 (Medium Industrial) zoning, ample parking, skylights, and sweeping Flatiron mountain views. The north office suite features 5,800 SF with 10 offices, restrooms, and a break room, plus a 2,320 SF warehouse with drive-in access and loading ramp. The south office suite offers 2,040 SF with 5 offices and a restroom, and shared amenities include a professional reception area and large conference room. Set within three professionally landscaped acres, the site is ideally suited for manufacturing, warehousing, storage, or office-support operations. What truly makes this location stand out is its blend of functionality, connectivity, and natural beauty. Situated along Highway 72, a key regional corridor with easy access to major highways and Denver’s metro area, the property supports efficient logistics and commuter access. It is also conveniently located near the future Jefferson County Beltway, which will further enhance regional connectivity. Additionally, the site is close to the new Quantum Commons tech hub—a groundbreaking initiative on a 70-acre campus in Arvada dedicated to advancing quantum technology innovation and establishing Colorado and the Mountain West as global leaders in this emerging field. The fenced and gated outdoor storage yard provides additional operational flexibility not often found in similar spaces. With abundant natural light streaming through skylights and stunning views of the Flatiron Mountains, tenants benefit from a welcoming and inspiring environment. Moreover, the property’s rich historical context—evolving from Arvada’s roots as a gold rush settlement and agricultural hub to a modern industrial center—adds character and a strong sense of community. This combination of practical amenities, strategic location near cutting-edge innovation, and scenic surroundings makes 19000 HWY 72 an exceptional choice for businesses seeking a versatile and prestigious address in the Denver metro region.

Date on Market:

2025-08-11

Littleton Medical for Lease - Southwest Denver

TURNKEY DENTAL/MEDICAL OFFICE SPACE FOR LEASE LEASE RATE: $19.50/SF NNN AVAILABLE SPACE: +/- 2,750/SF BUILDING SIZE: +/- 5,500 SF IDEAL USES:MEDICAL, DENTAL, OR OTHER HEALTHCARE USES FULLY BUILT OUT | MOVE-IN READY 27 SURFACE PARKING SPACES YEAR BUILT: 2003

Property Type:

Office

Date on Market:

2025-08-06

Wheat Ridge Office for Lease - West Denver

Property Overview This locally-owned office/medical property is conveniently located one and one-half miles south of I-70 via Wadsworth Boulevard. Building amenities include abundant parking, responsive on-site ownership, efficient floor plans, and aggressive rental rates. Location Overview Wheat Ridge Medical Complex is a 34,935 square foot medical office building centrally located near the intersection of 38th Avenue and Wadsworth Boulevard in Wheat Ridge, Colorado. Wadsworth Blvd and 38th Avenues are major thoroughfares through Wheat Ridge, Denver, Lakewood, and Arvada and offer easy access to I-70. The subject property is prime medical or office space within blocks of Exempla Lutheran Medical Center.

Date on Market:

2025-05-13

Longmont Flex, Industrial for Lease - Weld County

Flex Building with GMP Certified Production Space, Office, and Warehouse – Heavy Power (440v / 1200 amp) with Dedicated Transformer – Acrylic-Sealed Floors, Full HVAC, Air Lines, Fire Sprinklers, Floor Drains & Multiple Sinks – Natural Light Throughout Office & Manufacturing Areas – Convenient to Interstate 25, Highway 287 & Local Amenities – Flexible PUD Allows Any Use in Weld County Zoning C-3 & I-1

Date on Market:

2025-05-06

Aurora Flex for Lease

2,000 SF office/warehouse condos for sale/lease For sale at just $400,000 Lease for just $3,000/mth MG* Zoned I-1 industrial in the city of Aurora (Arapahoe County) Heavy power available Has a 10'x10' drive in door with 13'-14' clear height Association Dues are just $471.58 per month Property Taxes are approximately $8,556 per year Great for marijuana related uses, automotive repair or general office/warehouse uses.

Date on Market:

2025-04-16

Louisville Industrial for Lease - Boulder County

Date on Market:

2025-03-20

Boulder Industrial for Lease

Strategically positioned near Highways 52 and 119, this versatile industrial building offers excellent access to Boulder, Longmont, and I-25. Designed for flexibility, the property features a combination of office, laboratory, production, and warehouse spaces, previously utilized as a food lab and pilot plant. Key amenities include: • 2 dock-high doors, 2 truck-high doors, and 2 grade-level doors for seamless logistics and operations. • Abundant power supply and upgraded HVAC systems throughout the facility. • Full sprinkler system throughout for enhanced safety. • Multiple floor drains and trench drains, supporting diverse industrial applications.

Date on Market:

2025-01-15

Denver Office for Lease - CBD

Welcome to The 410, a modern office in Denver’s Skyline District, designed to take care of tenants’ well-being, supporting them to perform at their peak. This building offers a plethora of amenities, including a modern coffee and wine bar, indoor and outdoor meeting spaces, outdoor lounge, conference spaces, and a state-of-the-art fitness center. Above the renovated lobby, the building’s 24 rectangular floors are spacious and energizing, with discreet columns and inspiring views across Denver’s Front Range. Ample retail amenities surround the property, including lodging, shopping, dining, and nightlife. Culture, creativity, design, innovation, and nature are all hallmarks of the new Upper Downtown. Plus, commuting is a breeze, with ample parking available on-site. W. Colfax avenue/I-70 is just a few blocks from the property, providing easy access to I-25. Alternatively, the area is adjacent to the 16th Street Free Mall Ride and adjacent to Light Rail stops. For business travelers, the Denver International airport is a 30-minute drive.

Date on Market:

2025-07-07

Loveland Flex for Lease - Outlying Larimer County

3800 N. Wilson Avenue presents a remarkable and rare opportunity for high tech manufacturing and life science users within Loveland, Colorado. This 221,000+ square foot campus sits on approximately 38.467 acres, offering ample space for production and research, as well as potential future expansion. Located in Loveland, in between Colorado State University and CU Boulder, this facility offers easy access to a skilled workforce and synergistic business environment. This property is well suited for aerospace and defense users, life science users, biotechnology users, and manufacturing users. HIGHLIGHTS • Flexible manufacturing spaces adaptable to various high tech processes. • Robust power infrastructure to support heavy machinery and sensitive equipment. • Employee amenities such as the cafeteria and charming grounds featuring numerous trees and ponds. • Ample parking. • Privately gated campus. Main Facility - 204,542± Sq. Ft. (YOC 1991) ATS Building - 8,964± Sq. Ft. (YOC 2013) Garden Building - 5,460± Sq. Ft. (YOC 1992) Garden Shed - 2,400± Sq. Ft. (YOC 1992) Total - 221,366± Sq. Ft.

Property Type:

Industrial

Date on Market:

2024-09-20

Centennial Retail, Flex for Lease

Strong ownership with recently completed property upgrades including new exterior paint, new roofs, new HVAC, and parking lot resurfacing.

Date on Market:

2025-06-09

Longmont Flex for Lease

Property Type:

Office

Date on Market:

2025-07-29

Watkins Flex, Industrial for Lease - Outlying Arapahoe County

3MW power available now and potential to add more Campus building and 800 Acrage with secured gate access for lease, heavy industrial zoning allows variety of usages- 30 min Denver International Airport and 10 min from Aurora, CO.250,000 gallons private water tank 50-60 million gallons more available each year

Date on Market:

2025-11-07

Aurora Office for Lease

This recently renovated office building is located in a great SE Aurora location. The building features an updated lobby, updated units, and abundant free parking. A responsive local landlord. Current spaces available include heavy power lab space, open floorplans and traditional office. This building is within walking distance of the RTD 9-Mile Light Rail & Bus Station. Proximity to Parker Rd. & I-225 assures easy access, with numerous retail and restaurant amenities nearby.

Date on Market:

2024-02-15

Loveland Office for Lease - Fort Collins/Loveland

• Office Space: Exquisite office environment within the Loveland Tech Center, offering exceptional amenities and a professional atmosphere. • Endless Parking: Enjoy ample parking space for employees and visitors. • Elevator Access • Sprinkler System • Abundant Natural Light: Large windows allow for plenty of natural light. • Great Power: Benefit from great power capacity, catering to various office and lab needs. 200-800 Amps; 3-phase 2,594 - 8,191 SF $16.95 / SF / NNN $7.68 / RSF (Est. 2024) Flexible • Lab Space Potential: Explore the potential to convert the space into a lab, adding versatility to the property. • Prime Exposure: Enjoy prime exposure along Route 287, with building signage available to long-term tenants. • Convenient Location: Situated conveniently for commuters from Fort Collins, Loveland, and Boulder County, making it easily accessible to a broad talent pool. • Professional and Attentive Property Management • New Ownership

Property Type:

Flex

Date on Market:

2024-01-02

Boulder Office, Flex for Lease

Date on Market:

2024-04-09

Louisville Flex for Lease - Boulder County

Welcome to The Collective at Colorado Tech Center, where quality and connectivity amplify productivity in a Denver metro professional hub quickly rising to prominence. As part of the 5MM sq. ft. Colorado Tech Center (CTC), modern workspaces await at The Collective, offering a selection of sleek, newly built condo units sporting market-leading efficient design, engineering, and aesthetics. The units are insulated, air-conditioned with each having independent control, and illuminated by natural light from glass-paneled overhead doors and skylights. Many of the units have built-in mezzanines, providing this space-maximizing feature at a lower cost than post-sale installations. Clear heights range from 20 to 24 feet, creating a comfortably spacious feel that can conform with racking modules, and the drive-in doors are generously sized at 12 feet by 12 feet. Turnkey build-outs and combined unit size options enhance the flexibility for space needs from office administration to aerospace design to laboratories to storage. The Collective can host intensive operations with 1,600-amp power (upgradable) accommodating heavy machinery and advanced lab users. Built and operated by a development group with an exceptional and reputable 46 year legacy of projects in West Metro Denver, they're nimble and able to make sensible, quick decisions, offering faster, more creative deal-making than corporate sellers. Louisville and the surrounding areas between Downtown Denver and Boulder have a palpable energy as major companies, talented workers, amenity destinations, and infrastructure invigorate the locale. Demographics reinforce this as the number of households grew by 7.2% from 2020 to 2024 within a 5-mile radius and 60% of residents in that area have bachelor’s degrees or higher. Just within the immediate vicinity of The Collective, top companies, including Lockheed Martin, Specialized Bicycles, Esri, and Spectralink, operate here largely because this location attracts and retains talent. 10 minutes away, the Rocky Mountain Metropolitan Airport has added to the area’s popularity with its new JSX service offering public nonstop flights to Dallas, Las Vegas, Burbank, Salt Lake City, and Phoenix – an exceedingly more convenient option than DIA. That and its private jet services offer convenience to companies and their leaders. Employees also have an abundance of amenities at their disposal with Interlocken and Flatirons Crossing minutes away. County hiking and biking trails are just below the site, and the Aquarius trail system is just across CO Highway 42. Discover how The Collective’s prioritization of quality and versatility places it in a class of its own and empowers businesses to be more productive in a professional hub poised for dominance.

Date on Market:

2023-09-11

Grand Junction Industrial for Lease

Grand Mesa Industrial Park is a campus offering multiple space configurations ranging from 4,000 SF to 115,000 SF. Campus includes 5 industrial buildings. Industrial amenities include multiple bridge cranes, 3 ton and 10 ton, floor drains, large 20' x 24' overhead doors, ceiling height - 26', power - 3 phase, enclosed truck wash, truck lube, chemical storage, and large fenced, secured yard. A stand-alone two story office building is located at the north entry. The property is located within an Enterprise Zone and also in the Opportunity Zone which offer various tax credit incentives. The industrial park is located on the southeast edge of Grand Junction, CO just 2.5 miles south of I-70, the region`s main east-west connector. US Hwy. 50 is 3 miles to the south.

Date on Market:

2025-10-16