47 Life Science Properties for Lease in Colorado, USA

Denver Office/Medical, Medical for Lease - East I-70/Montbello

The Green Valley Ranch Medical Office Building at 4809 Argonne Street in Denver, Colorado, offers healthcare providers a premier opportunity to lease medical office space within one of Denver’s fastest-growing communities. Located approximately 17 miles east of Downtown Denver, this two-story, 45,767-square-foot medical office building features a strong tenant mix that includes primary care, urgent care, dental, vision, laboratory services, and an on-site pharmacy, creating a built-in referral network that supports patient retention and practice growth. Recently renovated common areas enhance the professional environment and patient experience, while ownership and management by Lillibridge Healthcare Services ensure high standards of building operations, responsiveness, and long-term stability. The first-floor space availability includes a move-in-ready, fully built-out spec suite. Green Valley Ranch Medical Office Building offers convenient patient access, covered patient drop off, ample on-site parking, and 24/7 on-call maintenance to support uninterrupted operations. The flexible leasing structure includes competitive rental rates and tenant improvement allowances to accommodate a wide range of medical build-outs, including clinical, outpatient, and specialty care uses. Biotech and lab space further expand the potential for advanced healthcare tenants. Green Valley Ranch Medical Office Building is strategically positioned at a signalized intersection, providing seamless ingress and egress. The building benefits from excellent regional connectivity, with direct access to Interstates 70, 225, and Highway 470, and is found just minutes from Denver International Airport. Bus line access makes the property easily accessible for both patients and staff. The surrounding area is anchored by new retail amenities and the award-winning Green Valley Ranch Golf Club, reinforcing the building’s role as a preferred healthcare destination for residents. With its prime location, established healthcare presence, and professionally managed environment, Green Valley Ranch Medical Office Building presents an exceptional opportunity for medical providers seeking to grow their practice in a thriving Denver healthcare corridor.

Date on Market:

2025-08-14

Greenwood Village Office for Lease

BE A PART OF SOMETHING BOLD Colorado Health & Tech Centers is bringing first-to-market space solutions for businesses that thrive in a fast-paced community. BUILD-TO-SUIT SOLUTIONS Tenants will see their innovative dreams become a reality as Colorado Health & Tech Centers can provide turnkey workspaces equipped with state-of-the-art features. Spaces range from 1,000 to over 100,000 square feet and are offered at aggressive rates. Whether a workspace environment is intended for office use, tech, life-science, or medical use, the team at CHTC will be there to find the perfect solution. WHERE INNOVATION COMES TO THRIVE CHTC-Greenwood Village seeks to form a synergy with its community of advanced organizations and Colorado’s talented professionals. CHTC aims to foster partnerships with regional universities to keep talent in Colorado, and its founder is already leveraging his deep roots in the medical community to develop a pipeline of the state’s top graduates. LIFESTYLE LOCATION 5800 S Quebec Street is adjacent to the Denver Tech Center, a primary professional hub known for its major companies largely specializing in technology and medical industries. As a result, well-educated households proliferate the area and 64% of the residents within a 3-mile radius have attained a bachelor's degree or higher. This advantageous address provides quick connections via Interstate 25, allowing drivers to reach as far as Downtown Denver, DIA, Boulder, Lakewood, and more in 20 to 40 minutes. Public transit users can walk to a light rail stop, and the immediate area is replete with lifestyle amenities. The Landmark, Target, REI, Sprouts Farmers Market, Fiddlers Green Amphitheater, multiple fitness options, over a dozen hotels, 100+ restaurants, and much more are all within 2 miles of the site. Discover this catalyst to propel business forward and get off the ground at CHTC-Greenwood Village today.

Date on Market:

2025-04-02

Denver Office for Lease - Colorado Blvd/I-25

Welcome to 2145 S Clermont St in Denver’s University Hills, an inviting two story office building with flexible leasing options that make it easy to right size your space today and grow tomorrow. Offered at $16/SF all in (inclusive), the building can be leased as individual suites (~1,100 SF), by the floor (2,300 SF), or as the full 4,660 SF building, which is a great fit for small businesses, start ups, or companies expanding into a location that can scale with them. With direct access to I-25 and a convenient, central Denver setting, this property offers a practical, welcoming workplace for teams who want flexibility, visibility, and a professional home base, updated with a 2025 renovation.

Date on Market:

2026-02-04

Boulder Office for Lease

Ideas tend to flow better when the setting does too. Located beside a creek and trail system, this 4,200 SF space offers a rare blend of flexibility and tranquility. Ideal for educational organizations, office users, or groups seeking a calm, adaptable workspace, it’s designed to support focus today and evolve tomorrow. Quiet, capable, and thoughtfully positioned—it’s a place where work feels intentional.

Date on Market:

2026-02-06

Louisville Industrial for Lease - Boulder County

Nicely finished distribution, manufacturing, lab, and office warehouse production space in the centrally located Colorado Technology Center, in Louisville. The space offers open office layout, six private offices, breakroom/kitchen, conference room, inventory area, lab or food production space, and open warehouse with drive-in access, and heavy power. • Move-in Ready Office, Warehouse,& Lab Space • Three (3) Grade -Level Overhead Loading Doors • Previously GMP Certified Food/Dietary Production Space • 16’ Clear Height

Property Type:

Flex

Date on Market:

2026-01-27

Louisville Flex for Lease - Boulder County

Kinsey & Company Commercial Real Estate is pleased to present The Collective I, a premier Class A office/flex opportunity located at 199 S. Taylor Street in Louisville. Completed in 2020, this modern multi-tenant asset totals 37,231 square feet, including mezzanine space, and sits on a 3.17-acre site within one of Boulder County’s most desirable and supply-constrained submarkets. The property is offered for sale or for lease, providing exceptional flexibility for owner-users, investors, and tenants. The Collective I accommodates a wide range of business strategies through three distinct acquisition and occupancy paths: (i) tenants may lease individual suites or multiple contiguous spaces, (ii) users may purchase an office/flex condominium to own and occupy their space, or (iii) buyers may acquire the entire building, occupy available suites, and continue leasing to the existing professional tenant base. Available spaces range from 3,780 to 26,084 square feet, allowing the property to serve both small and expanding organizations. Designed to a high standard, the building features clear heights of 20’–24’, 12’ x 12’ rear overhead glass doors, polished concrete floors (with upgrade options), and storefront glass glazing with custom signage mounts. Select suites offer turn-key clinical research lab space, while others are delivered as office spec-suites, providing immediate occupancy solutions. Each unit is individually metered for gas and electric, includes separate HVAC systems, and is internet-ready, offering operational efficiency and control for occupants. An abundant 4.1 per 1,000 SF parking ratio, accessible rear loading, and optional security and camera prewire surveillance further enhance functionality. Landscape maintenance is professionally managed by the HOA. Strategically located, The Collective I offers exceptional regional connectivity with immediate access to I-25, providing a direct commute to downtown Denver, and convenient access to Highway 36, connecting to downtown Boulder. The property also benefits from close proximity to Downtown Louisville, offering nearby dining, retail, and lifestyle amenities that appeal to employees and clients alike. The building is anchored by a strong roster of professional co-tenancy, including Peak Retirement Planners, Pigler Automation and Tandem Certified Public Accountants, creating a stable and synergistic business environment. With its modern construction, flexible ownership and leasing options, and premier Boulder County location, The Collective I represents a compelling opportunity for users and investors seeking long-term value in a high-demand market.

Date on Market:

2026-01-27

Englewood Office/Medical for Lease - Inverness

Suite 120 at 195 Inverness Dr W offers 1,668 SF of existing medical lab space with excellent potential for conversion to a primary care or concierge medical practice. Located in the heart of the Inverness / DTC submarket, the suite benefits from ground-floor access, a rare covered building drop-off, abundant parking, and immediate access to I-25 and E-470. Surrounded by corporate campuses, hotels, and executive housing, this is an ideal setting for boutique healthcare providers seeking a professional image and strong patient convenience.

Property Type:

Office

Date on Market:

2026-01-20

Colorado Springs Flex for Lease - Northwest

980 Elkton Drive offers highly flexible office / lab space for lease in a well-located business park just west of I-25 off Garden of the Gods Road. The property features an open layout adaptable for lab or technical users and the ability to add overhead doors for enhanced functionality. 8,237 - 17,572 SF of office / lab space available NNN Expenses excludes maintenance and janitorial

Date on Market:

2026-01-13

Broomfield Flex for Lease - Broomfield County

Now available for lease, this brand new 18,284 square foot flex building offers exceptional versatility and can be built out to suit nearly any business use. The space may be divided into units as small as ~4,500 square feet (Main floor: 3,200SF and Mezzanine: 1,300SF), providing flexible options for any size business. The building is designed to accommodate a wide range of uses including showroom, light industrial, R&D, service, office, or creative workspace. Floor plans, finishes, and utility configurations can be customized to meet tenant requirements. Drive-in doors to be added where needed. This adaptable flex space is ideal for businesses seeking a modern facility that can is tailored to their current needs and can adapt to their growth plans.

Date on Market:

2026-01-05

Broomfield Industrial for Lease - Broomfield County

Broomfield’s newly built Dry Creek Business Park offers flexible industrial spaces ranging from 2,240 to 18,284 square feet, allowing tenants to tailor layouts to their specific operational needs. Tenant improvement allowances are potentially available to accommodate specific build-out requirements. The building features 540-amp, 208-volt, 3-phase electrical service and is equipped with four (4) overhead doors. Zoning supports a wide range of uses, including light manufacturing, assembly, warehousing, distribution, research and development, professional office, and more. With excellent access to both Denver and Boulder, Dry Creek Business Park provides a modern, functional option in one of the region’s most supply-constrained industrial corridors.

Property Type:

Flex

Date on Market:

2025-12-11

Denver Office/Medical for Lease - Southwest Denver

Owner will fund a full tenant improvement remodel for qualified long-term tenants. Whether you need the space as-is or completely reconfigured for a new use, we will build it to your specifications. This is not just a medical building — it is a flexible, infrastructure-rich professional space adaptable to a wide range of uses. Medical & Clinical Uses: Urgent care / walk-in clinic, med spa / aesthetics / Botox, dermatology, physical therapy / sports rehab, dental, orthodontics, veterinary clinic (nitrous oxide/O2 infrastructure already in place), chiropractic, acupuncture, pediatric therapy (OT/speech/ABA), oral surgery, optometry, podiatry, or specialty medical group practice. Behavioral Health & Wellness: Therapy group practice (5–10 private rooms ready for individual counselors/therapists), psychiatry, psychology practice, substance abuse / addiction counseling, marriage & family therapy, ABA therapy, dietitian / nutritionist practice, integrative / functional medicine, or wellness coaching center. Professional & Educational: Home health / hospice agency administration, medical billing office, insurance agency, financial planning / wealth management office, tutoring / test prep center, real estate brokerage, staffing / recruiting agency, nonprofit organization, law office, accounting / CPA firm, or coworking / flex office space. Dual-Tenant Configurations: The two-floor layout with fully separate entrances, receptions, and restrooms supports two independent businesses operating under one roof. Pair a patient-facing medical practice on the upper level with a therapy group, professional office, or learning center on the lower level — each with complete operational independence and zero shared spaces. Why This Space: Every treatment room has water and plumbing. The upper level has 10 plumbed rooms; the lower level has 5 plumbed rooms plus nitrous oxide/O2 gas lines. Panoramic X-ray rooms, sterilization labs, dark rooms, and clinical-grade electrical on both floors. Existing infrastructure saves incoming tenants an estimated $50,000–$100,000+ compared to building out raw shell space. Parking lot fully resurfaced Fall 2025.

Property Type:

Office

Date on Market:

2025-11-21

Watkins Coworking for Lease - Outlying Arapahoe County

Property Type:

Office

Date on Market:

2025-11-10

Greenwood Village Office for Lease

6080 Greenwood Plaza Blvd is an 8,771-square-foot office and lab building located in the heart of Greenwood Village. The property features well-finished office space with a dedicated 553-square-foot lab and clean room. Built in 1979 and zoned PUD within The Commons, the building offers flexible suite configurations and quality improvements suitable for a variety of professional, medical, or technical uses. The location provides excellent access to I-25, public transportation, and surrounding retail and dining amenities.

Date on Market:

2025-10-28

Colorado Springs Office for Lease - Southeast

980 Technology Court offers a rare opportunity for large-block users to secure high-quality office space in the established Patriot Park business park. With ±20,170 SF available in a single, efficient floor plan, the property is ideally suited for defense contractors, government users, call centers, and large-scale professional service operations seeking a secure and scalable environment. Key features include ample surface parking (3.8/1,000 SF ratio), updated office finishes, and strong infrastructure to support high-density or specialized uses. Located just minutes from Peterson Space Force Base, Colorado Springs Airport, and Powers Boulevard, the site provides excellent connectivity to both workforce and regional amenities. Surrounded by leading aerospace, technology, and defense firms, 980 Technology Court positions tenants at the center of Colorado Springs’ growing innovation corridor. With a strong landlord and competitive economics, this property delivers the size, efficiency, and location rarely available in today’s market.

Date on Market:

2025-10-20

Erie Flex for Lease - Weld County

3000 Airport Drive is located in Erie Colorado, adjacent to Erie Airport. A master planned creative business park consisting of 61,250 total square feet of zoned light industrial/flex or airport units. All units have airport access to Erie Municipal Airport via a private taxiway and adjacent to Colorado National Golf Club home of CU Buffs Golf and Anthem a 3,400-acre master planned community. Allowing light industrial, aviation related businesses, light manufacturing. The property offers a 6,250 square foot space for lease currently operating as a full service manufacturer of precision metal products. Strategically located just off of Baseline Road, being minutes to I25, 30 minutes to Denver International Airport and 30 minutes to downtown Boulder Colorado. 10 minute or less drive to several restaurants, grocery stores, entertainment, Costco, Home Depot, Hotels, shopping and more.

Date on Market:

2025-09-24

Arvada Industrial for Lease - West Denver

Discover a rare leasing opportunity in Arvada with two spaces available individually or together, including a 12,615 SF stand-alone light industrial building and a 1.5-acre fenced and gated outdoor storage yard. Perfectly located off Highway 72 between Indiana Street and Highway 93, the property offers I-2 (Medium Industrial) zoning, ample parking, skylights, and sweeping Flatiron mountain views. The north office suite features 5,800 SF with 10 offices, restrooms, and a break room, plus a 2,320 SF warehouse with drive-in access and loading ramp. The south office suite offers 2,040 SF with 5 offices and a restroom, and shared amenities include a professional reception area and large conference room. Set within three professionally landscaped acres, the site is ideally suited for manufacturing, warehousing, storage, or office-support operations. What truly makes this location stand out is its blend of functionality, connectivity, and natural beauty. Situated along Highway 72, a key regional corridor with easy access to major highways and Denver’s metro area, the property supports efficient logistics and commuter access. It is also conveniently located near the future Jefferson County Beltway, which will further enhance regional connectivity. Additionally, the site is close to the new Quantum Commons tech hub—a groundbreaking initiative on a 70-acre campus in Arvada dedicated to advancing quantum technology innovation and establishing Colorado and the Mountain West as global leaders in this emerging field. The fenced and gated outdoor storage yard provides additional operational flexibility not often found in similar spaces. With abundant natural light streaming through skylights and stunning views of the Flatiron Mountains, tenants benefit from a welcoming and inspiring environment. Moreover, the property’s rich historical context—evolving from Arvada’s roots as a gold rush settlement and agricultural hub to a modern industrial center—adds character and a strong sense of community. This combination of practical amenities, strategic location near cutting-edge innovation, and scenic surroundings makes 19000 HWY 72 an exceptional choice for businesses seeking a versatile and prestigious address in the Denver metro region.

Date on Market:

2025-08-11

Littleton Medical for Lease - Southwest Denver

TURNKEY DENTAL/MEDICAL OFFICE SPACE FOR LEASE LEASE RATE: $19.50/SF NNN AVAILABLE SPACE: +/- 2,750/SF BUILDING SIZE: +/- 5,500 SF IDEAL USES:MEDICAL, DENTAL, OR OTHER HEALTHCARE USES FULLY BUILT OUT | MOVE-IN READY 27 SURFACE PARKING SPACES YEAR BUILT: 2003

Property Type:

Office

Date on Market:

2025-08-06

Wheat Ridge Office for Lease - West Denver

Property Overview This locally-owned office/medical property is conveniently located one and one-half miles south of I-70 via Wadsworth Boulevard. Building amenities include abundant parking, responsive on-site ownership, efficient floor plans, and aggressive rental rates. Location Overview Wheat Ridge Medical Complex is a 34,935 square foot medical office building centrally located near the intersection of 38th Avenue and Wadsworth Boulevard in Wheat Ridge, Colorado. Wadsworth Blvd and 38th Avenues are major thoroughfares through Wheat Ridge, Denver, Lakewood, and Arvada and offer easy access to I-70. The subject property is prime medical or office space within blocks of Exempla Lutheran Medical Center.

Date on Market:

2025-05-13

Longmont Flex, Industrial for Lease - Weld County

Flex Building with GMP Certified Production Space, Office, and Warehouse – Heavy Power (440v / 1200 amp) with Dedicated Transformer – Acrylic-Sealed Floors, Full HVAC, Air Lines, Fire Sprinklers, Floor Drains & Multiple Sinks – Natural Light Throughout Office & Manufacturing Areas – Convenient to Interstate 25, Highway 287 & Local Amenities – Flexible PUD Allows Any Use in Weld County Zoning C-3 & I-1

Date on Market:

2025-05-06

Aurora Flex for Lease

2,000 SF office/warehouse condos for sale/lease For sale at just $400,000 Lease for just $3,000/mth MG* Zoned I-1 industrial in the city of Aurora (Arapahoe County) Heavy power available Has a 10'x10' drive in door with 13'-14' clear height Association Dues are just $471.58 per month Property Taxes are approximately $8,556 per year Great for marijuana related uses, automotive repair or general office/warehouse uses.

Date on Market:

2025-04-16

Louisville Industrial for Lease - Boulder County

Date on Market:

2025-03-20

Lafayette Office, Flex for Lease - Boulder County

This is an ideal Flex space for multiple uses. Great Private offices, an open Bullpen, potential warehouse space. Lease Rate: $15.95/SF NNN NNN Expenses: $10.00/SF Building Size: 20,313 SF Available SF: 5,622 SF Parking: 2.5/1,000 SF Year Built: 2001 Zoning: M-1 (Lafayette)

Date on Market:

2025-12-22

Boulder Industrial for Lease

Strategically positioned near Highways 52 and 119, this versatile industrial building offers excellent access to Boulder, Longmont, and I-25. Designed for flexibility, the property features a combination of office, laboratory, production, and warehouse spaces, previously utilized as a food lab and pilot plant. Key amenities include: • 2 grade-level doors for seamless logistics and operations. • Abundant power supply and upgraded HVAC systems throughout the facility. • Full sprinkler system throughout for enhanced safety. • Multiple floor drains and trench drains, supporting diverse industrial applications.

Date on Market:

2025-12-09

Denver Office for Lease - CBD

Welcome to The 410, a modern office in Denver’s Skyline District, designed to take care of tenants’ well-being, supporting them to perform at their peak. This building offers a plethora of amenities, including a modern coffee and wine bar, indoor and outdoor meeting spaces, outdoor lounge, conference spaces, and a state-of-the-art fitness center. Above the renovated lobby, the building’s 24 rectangular floors are spacious and energizing, with discreet columns and inspiring views across Denver’s Front Range. Ample retail amenities surround the property, including lodging, shopping, dining, and nightlife. Culture, creativity, design, innovation, and nature are all hallmarks of the new Upper Downtown. Plus, commuting is a breeze, with ample parking available on-site. W. Colfax avenue/I-70 is just a few blocks from the property, providing easy access to I-25. Alternatively, the area is adjacent to the 16th Street Free Mall Ride and adjacent to Light Rail stops. For business travelers, the Denver International airport is a 30-minute drive.

Date on Market:

2025-07-07