47 Life Science Properties for Lease in Colorado, USA

Boulder Office for Lease

– Tranquil Office Adjacent to Boulder Creek with 3 Balconies & Great Views – 8 Private Offices, Large Open Work Area with Modular Furniture in Place, Kitchenette Break Area, Server Room & Common Shower in the Building – Covered & Uncovered Parking with a Ratio of 4.46:1,000 sq. ft. – Professional, Tech or Admin Office Allowed By-Right & Medical Allowed as a Conditional Use – Direct Access to the Boulder Creek Bike Path System

Date on Market:

2025-04-29

Boulder Office for Lease

Date on Market:

2025-03-10

Littleton Office/Medical for Lease - Southwest Denver

Set up an office location or medical practice decidedly located among desirable professional, residential, and lifestyle destinations that propel the success of any business. 991 Southpark Drive is a two-story commercial building spanning approximately 18,000 square feet in the Ridge at Southpark, situated toward the west to maximize mountain views. Its modern angular architecture, spearheaded by the prominent glass atrium, creates a distinct identity for tenants, which can then be reinforced by the monument signage. The building is ADA-compliant. It has an elevator and ample parking with curb cuts for easy wheelchair access, which is ideal for healthcare tenants. The available space is suited for more than just medical users as its current condition allows tenants to design a wholly custom space or occupy it quickly. Spaces at 991 Southpark Drive offer a lot of versatility, from flexible sizing plans to partially furnished or shell space options with build-to-suit opportunities. Each has its own private restroom, and tenants’ spaces truly feel like their own for employees and visitors. This is the perfect location for a myriad of industries, including medical, dental, tech, finance, life science / lab work , research , finance , law , and more, as the area is replete with synergetic destinations. High-profile companies like Lockheed Martin, Visa, Kaiser Permanente, HCL America, Software AG, and AdventHealth all occupy a significant amount of space within a 2-mile radius, underpinning the desirability of this area for a diverse range of businesses. Tenants have their pick of some of the best-educated talent in the Denver metro as places like Littleton and Highland Ranch gain popularity with that demographic. A reported 56% of the population, including non-adults, have a bachelor's degree or higher. An array of parks, shopping centers, golf courses, hospitals, and charming neighborhoods characterize the area’s main draws and provide multifaceted benefits to professionals. 991 Southpark Drive’s proximity to Sante Fe Drive and E 470 streamlines access to those attractions and makes it one of the most commutable office locations.

Property Type:

Office

Date on Market:

2022-08-25

Arvada Office, Flex for Lease - Northwest Denver

Introductory Rates Starting at $9 NNN on the First Floor and $16 NNN on the Second Floor! -2nd Floor Remodeled Office is Available in Full (10,245 sf) or as Two Suites Featuring Open and Private Offices, Reception Area, Full Kitchen and Restrooms with Showers -1st Floor Suite is Available in Full (4,163 sf) or as Two Suites Featuring Office & Flex Areas, Kitchen, Lab, Secure Storage and Private Restrooms -Building Features 3:1,000 Parking Ratio with 10 Covered Spaces -Hiking & Biking Trails Just Steps Away in Broad Lake Park – Many Amenities and Thoroughfares in Close Proximity: I-70 - 2.5 Miles South; US-6 - 6 Miles South; I-25 - 9.5 Miles East

Date on Market:

2025-10-24

Broomfield Office, Flex for Lease - Broomfield County

Flex Building Featuring Office and Labs Spaces with Grade and Dock-High Loading - The Building is Equipped with Heavy Power & Life Science Infrastructure Options - Convenient to Denver & Boulder with Abundant Parking Ratio of 3.75 : 1,000 - Nearby Amenities Include Rocky Mountain Airport, Flatirons Mall, Omni Hotel & Golf Course

Date on Market:

2025-02-11

Lafayette Flex for Lease - Boulder County

Well-located flex/office building steps from Coal Creek path and easy walk to Old Town Lafayette.

Date on Market:

2024-04-16

Colorado Springs Industrial for Lease - North

This centrally located, highly functional industrial facility has up to 59,452 SF of office, lab, manufacturing and warehousing space available for lease. Heavy 480v power distributed throughout, large parking and truck courtyard space offers outside storage potential. Over 11,000 SF of office/lab space on two floors. Easy all points access via Mountview or Fillmore to Nevada with close proximity to 1- 25 interchanges at Fillmore Street and North Nevada/Rockrimmon/Corporate Dr.

Date on Market:

2025-08-29

Castle Rock Office/Medical for Lease - Parker/Castle Rock

This Class A, 3 story medical office building was constructed in 2013. The building is located within the AdventHealth Castle Rock campus with easy access to US-87.

Property Type:

Office

Date on Market:

2025-02-18

Aurora Office for Lease

Date on Market:

2025-01-03

Parker Land for Lease - Centennial

2.72 AC retail pad for sale or ground lease Signalized intersection location at the Chambers Rd. exit off of E-470 At the entrance to the Cottonwood Development - over 2,000 domestic units National hotel, coffee & fast food concept coming soon directly across the street Automotive & daycare are approved uses

Property Subtype:

Commercial

Date on Market:

2025-04-25

Arvada Coworking for Lease - Northwest Denver

Property Type:

Office

Date on Market:

2023-09-13

Golden Flex for Lease - West Denver

Date on Market:

2025-11-14

Wheat Ridge Office/Medical for Lease - West Denver

The Intermountain Health Lutheran Medical Office Building (MOB) is a 5-story, 138,000-square-foot outpatient facility that recently opened its doors on the new 28-acre Lutheran campus. The new Lutheran Hospital campus including the Lutheran MOB is located in the larger Clear Creek Development which is home to retail, dining, hotel, residential, fitness and more! This independent MOB connects to the IH Lutheran Hospital via a pedestrian bridge on floor two. The hospital is also now open. Building services include IH cardiovascular care, cardiac rehabilitation, a sleep lab, maternal-fetal medicine, a weight loss center, a neurology & neurosurgery center, a joint-venture ambulatory surgery center (managed by SCA Health), and a laboratory. Independent physician groups including Hanger Prosthetics and Orthotics, Cornerstone Orthopedics, and Restorative Health Colorado will also be providing services in the facility.

Property Type:

Office

Date on Market:

2024-10-07

Broomfield Office for Lease - Broomfield County

Shovel ready! CoRE - Colorado Research Exchange will offer a purpose-built life science campus designed to create an ecosystem to accommodate a variety of users in life science, lab and technology.

Date on Market:

2022-05-09

Denver Office/Medical, Medical for Lease - East I-70/Montbello

The Green Valley Ranch Medical Office Building at 4809 Argonne Street offers an exceptional opportunity for healthcare providers looking to lease premium medical office space. This state-of-the-art facility meets modern healthcare demands with its comprehensive mix of specialties and stands out for its strategic location and accessibility. Designed with the needs of patients and providers in mind, this building is ideal for established and upcoming healthcare professionals seeking a premium location to grow their practice. Green Valley Ranch underwent a recent renovation of its common areas, further enhancing the environment and comfort for all who utilize the space. Owned and managed by industry leader Lillibridge Healthcare Services, this building provides a seamless blend of convenience, efficiency, and excellence, ensuring your practice can thrive in an exceptional place of care. Lease medical office space at Green Valley Ranch Medical Office Building and join a thriving healthcare community today!

Date on Market:

2025-08-14

Broomfield Coworking for Lease - Broomfield County

Spaces Arista is situated in a burgeoning urban lifestyle center at the core of the Boulder Denver corridor. As one of the premier main street retail destinations, this is an office with modern style and charm. Its striking brick and stone exterior with large glass windows fill the office with natural light while offering views to the bustling streetscape below. Open walkable spaces and casual seating areas cultivate exciting opportunities to collaborate with like-minded professionals and re-energize your mind. Within a stone’s throw, you’ll find a unique mix of restaurants and boutiques, and you can connect to Interlocken’s campus of hi-tech research and development corporations a few miles down the road. At Spaces Arista, Spaces can support with: • Office Space: Your own private and fully serviced office space with a flexible contract that adapts to your business and is accessible 24/7. • Coworking Membership: Work from thousands of coworking spaces worldwide, all with a flexible contract and unlimited access during business hours. • Dedicated Desk: Your own private desk in a shared office or open plan space that can be accessed 24/7, locker included, all with a flexible contract. • Meeting Rooms: Choose from thousands of on-demand meeting rooms and event spaces with all the services you need, fully customizable for any event or duration. • Virtual Office: Leave the best impression with a professional business address at one of Spaces locations and have Spaces handle your calls and mail. Just so you know; all images shown in this listing are from Spaces locations, but they may not correspond to this specific one.

Property Type:

Office

Date on Market:

2019-10-04

Boulder Office for Lease

Property Type:

Flex

Date on Market:

2025-05-01

Boulder Flex for Lease

Date on Market:

2025-02-18

Lafayette Flex for Lease - Boulder County

Located near the corner of South Public Road and South Boulder Road, 1376 Miners Drive is an excellent opportunity to sublease a large space with brand new finishes including state of the art commercial test kitchen infrastructure in place.

Date on Market:

2022-12-12

Aurora Flex for Lease

Date on Market:

2025-11-18

Longmont Office for Lease - Weld County

3 Brand new industrial buildings without door storage for sale or lease Buildings divisible in sizes between 5,549 SF - 23,000SF 24’ inside clear height 14’ x 14’ Overhead Doors & Dock Hi Options Power:1600A /Bldg Parking~67 spaces per building. 2.87/1000 & EV charging

Property Type:

Specialty

Date on Market:

2025-07-24

Boulder Flex for Lease

Date on Market:

2024-02-20

Longmont Office for Lease

This state-of-the-art facility features clean rooms, laboratories, office spaces, and a robust MEP infrastructure. SUPERIOR LOCATION The Property is located 10 miles from I-25 and only 5 miles from downtown Longmont. Situated 15 miles from Boulder, this location enables access to two superior talent pools.

Property Type:

Flex

Date on Market:

2023-09-14