64 Life Science Properties for Lease in Maryland, USA

Germantown Office, Flex for Lease

Building 10 at 20521 Seneca Meadows Parkway offers an incredibly high-tech life science building in a campus setting. This 73,166-square-foot lab space is constructed with efficient floor plates, 16-foot to 18-foot clear heights, and four dock-high enclosed loading bays. 20521 Seneca Meadows Parkway features a striking lobby and building signage opportunities. Ample space in two lots adjacent to Building 10 allows for at least 500,000 square feet of additional growth. In addition to the Seneca Meadows Corporate Center, tenants of Building 10 will appreciate campus amenities, including fully equipped conference rooms, a fitness center with private showers and locker rooms, Wi-Fi connectivity, a tenant lounge, and a coffee bar. Prominent corporate tenants in the center include Precigen, Sirnaomics, Senseonics, IBM, and Zebra. Nearby campuses include the University of Maryland, Montgomery College, and 36 Blue-Ribbon High Schools, all of which contribute to the vast employment pool in Germantown. Centrally located, 20521 Seneca Meadows Parkway is three minutes from Interstate 270, 12 minutes from ICC 200, 18 minutes from Interstate 495, 25 minutes from Frederick, Maryland, and 35 minutes from Washington, DC. Access to the corporate center is easy with the numerous nearby highways and public transportation nodes such as the MARC commuter rail. Retail complexes near Seneca Meadows Corporate Center include The Shops at Seneca Meadows, Milestone Center, and the Germantown Town Center, full of dining, shopping, and service options. Nearby national tenants include Walmart, Target, Best Buy, The Home Depot, Wegmans, Onelife Fitness, Panera Bread, and PetSmart. Germantown creates a sense of seclusion with the perfect blend of tranquil countryside and bustling city. Located 49 miles from Baltimore and 26 miles northwest of Washington, DC, Germantown is a premier spot for big-city convenience. The area's must-see locations and outdoor adventures include Seneca Creek State Park and South Germantown Recreational Park. Boasting a wide array of corporate neighbors in life science-related fields, abundant amenities, and a convenient location, 20521 Seneca Meadows Parkway is the ideal location for thriving businesses.

Date on Market:

2025-07-23

North Bethesda Office, Flex for Lease - Rockville

Greencourt Innovation Center at 12358 Parklawn Drive is meticulously designed with modern industrial-style finishes and unique building amenities that inspire and promote collaboration and creativity. Comprising spec offices, coworking spaces, biotech wet labs, and meeting areas, Greencourt Innovation Center supports enterprises at every stage in the growth cycle. The center offers a variety of workspace options for visionary, growth-focused companies to build and thrive. Tenants can host business meetings or private company events in one of the collaboration/meeting spaces, the executive conference center, the three-story meeting and event hall, and the floating boardroom. Greencourt Innovation Center elevates the tenant experience through community concierge services, including white-glove quality building services and engaging tenant programs to entertain and delight. Located in the North Bethesda Warehouse District, Greencourt Innovation Center is a 10-minute walk from the Twinbrook Metro Station, a five-minute drive to luxury retail, including Pike and Rose, and 3 miles from Interstates 270 and 495.

Date on Market:

2025-11-24

Lexington Park Office/Medical for Lease - St Mary's County

Expedition III at 46655 Expedition Drive boasts the highest elevation in Lexington Park, with unparalleled views of Three Notch Road and the surrounding area. The building offers top-tier office space located in Expedition Park, a beautiful campus setting surrounded by mature landscaping. This four-story, 63,520-square-foot building boasts efficient floor plates and a window-wrapped facade, allowing for abundant natural lighting. Suite 102 is a 4,359-square-foot office space available starting in Q1 2026, featuring a highly configurable and efficient layout for a broad range of businesses. It includes six private offices, one of which could be used for lab space, a lounge/copy area, a kitchen, and a storage room. Additionally, it has an expansive conference room that accommodates up to 95 people and can also serve as a workstation area. Nestled in a quaint suburban community, Expedition Park is adjacent to the main base gate at the Naval Air Station at Patuxent River (NAVPAX) and conveniently near numerous local amenities. Ideally situated off Three Notch Road, the area's main thoroughfare, the park provides easy commutes and seamless connections to Great Mills, Wildewood, and beyond. In less than a five-minute drive, reach Lexington Village shopping center, where tenants and visitors of the park can access several retailers, restaurants, and hotel options. Neighboring tenants include the Naval Air Station at Patuxent River and multiple defense contractors, as well as notable companies, including Raytheon, Sabre Systems, and Spalding Consulting, Inc. Well-maintained, with incredible accessibility, 46655 Expedition Drive is primed to offer an ideal office space.

Property Type:

Office

Date on Market:

2025-11-11

Rockville Office/Medical for Lease

Randolph Medical Center at 4701 Randolph Road offers fully built-out medical suites available now with flexible lease terms. The spaces feature efficient layouts for a broad range of healthcare and wellness users, with 2nd-generation suites configured for users like lab specialists, dental practitioners, and physical therapists. Randolph Medical Center is home to a great mix of medical specialties, offering synergy for future practices with abundant free parking to accommodate patients. Located at the intersection of Randolph Road and Gaynor Road, the center receives significant exposure and is easily accessible to patients from Silver Spring, Wheaton, Rockville, and Bethesda. Randolph Medical Center is surrounded by over 7,000 households within a 1-mile radius, with virtually no competition and numerous nearby amenities to enhance convenience. The area’s residents are highly health-conscious and affluent, placing practices among premier patient pools. These prospective clients can get to the property with ease via Route 355, Interstate 270, the White Flint Metro Station (Red Line), and Route 586.

Property Type:

Office

Date on Market:

2022-11-10

Frederick Multiple Space Uses for Lease

Ballenger Creek Business Center (BCBC) is a new 25-acre business campus located in the city of Frederick on Ballenger Center Drive just off I-70 and I-270. Once BCBC is completed, the project will consist of three buildings with 103,122 - 136,106 square feet of R&D/Biotech/office/flex and high-bay warehouse space in addition to the existing building. The project has Frederick City MO zoning allowing multiple uses including biotech, office, warehouse, distribution, and manufacturing. Each building will feature dock and drive-in loading with ample parking. BCBC is conveniently located near MedImmune / AstraZeneca in the I-270 biotech corridor with convenient access to Washington, D.C. via I-270, Northern Virginia via RT340/ RT15, and Baltimore via I-70. The center is conveniently located to Downtown Frederick with all its restaurants and local retail on Ballenger Creek Pike.

Date on Market:

2024-01-30

Baltimore Flex for Lease - Baltimore Southeast

Date on Market:

2026-01-08

Rockville Flex for Lease

Date on Market:

2025-12-11

Gaithersburg Office/Medical, Flex for Lease

Office/Medical/Flex--Immaculately maintained business center with a quiet park-like campus. Outstanding central location in Montgomery County, MD. Blocks to I-270 Exit 12 and easy access to Routes 200 & 355. Large variety of nearby restaurants, shopping, and complimentary access to fitness facility. Single story building with at-grade access, private entrance(s), multiple loading docks, emergency generator opportunity, plenty of parking and Ride-On bus accessible. NNN listing allows for independently controlled 24/7 access to suite and HVAC. High quality co-tenants such as Astra Zeneca, Biontech, L & J Bio, & SalubrisBio. and experienced ownership-Est. 1994, Alexandria© is an S & P 500 urban office REIT with over 3+ million SF locally and 39+ million SF nationally specializing in life sciences and technology and driven to inspire dynamic and collaborative environments. Gaithersburg city I-3 zoning allows for a variety of uses including medical, lab, office and flex.

Date on Market:

2025-10-08

Frederick Office, Flex for Lease

Coldwell Banker Commercial Realty is pleased to announce the exclusive listing of Westview Corporate Campus – Building 1, located at 7215 Corporate Court in Frederick, Maryland, for lease. Situated within Frederick County’s premier planned corporate campus, the property is ideal for corporate headquarters, office, research and development, and communications-related operations. The campus offers a host of amenities, including convenient access to nearby retail shops, restaurants, and day care facilities. Strategically located, it provides easy connectivity to major highways such as I-270, I-70, US Route 15, Route 355, and Route 85, and is just five minutes from the Frederick Municipal Airport, a full-service general aviation facility. Designed with both function and aesthetic appeal in mind, the building features an atrium-style lobby adorned with skylights and architectural finishes of oak, slate, and marble. Each floor offers both ground-level and dock access, and includes advanced digital fiber optics, pre-wiring for emergency generator systems, and energy-efficient lighting fixtures. Additional highlights include insulating solar-grey glass windows, a brick walkway leading to a sheltered entry, and column-free spaces as large as 6,000 square feet on the second floor to accommodate flexible interior layouts. The ceilings measure 8'6" in height, with the potential to increase up to 11'. Tenants will also benefit from a cost-efficient, programmable energy management system and generous free parking with 196 available spaces.

Date on Market:

2025-12-09

Germantown Office, Office/Medical for Lease

The newest life science conversion in Montgomery County, Observation Labs at 20400 Observation Drive, offers superior lab space in the heart of the Germantown life science cluster, supporting tenants in all stages of their research. This two-story, multi-stage life science building provides immediate move-in-ready options and build-to-suit opportunities, leading the way with design innovation and next-generation lab space. Phase 1 offers two remaining turnkey spec suites at 5,648 square feet and 3,847 square feet. Phase 2 is ready for tenant construction, where tenants can expand or customize their build-out. Best-in-class renovations include a new lobby, creative seating options, healthy food options in the gourmet kitchen, and shared biotech equipment, including an autoclave, a glassware washer, a deionized water system, and a flake ice machine to be shared by tenants. Critical infrastructure systems, such as a new generator and a fresh air HVAC, are in place to support life science users. Observation Labs features loading docks on each level, a 480-volt electrical supply, emergency power, and ample parking. Within minutes of the property are numerous retailers, dining options, and entertainment. With access to Interstate 270 just a quarter-mile away, Observation Labs provides an easy commute and a seamless connection to Frederick and Bethesda. Reagan Washington National, BWI, and Dulles International Airports are less than an hour away for convenient out-of-town travel. Germantown is a premier location blending urban amenities alongside picturesque suburban and natural landscapes. When research, connectivity, and convenience are key, Observation Labs is the ideal destination for your lab space.

Date on Market:

2025-09-11

Rockville Office for Lease - North Rockville

Date on Market:

2024-06-05

Rockville Office for Lease

Property Type:

Flex

Date on Market:

2025-06-27

Baltimore Office, Flex for Lease - Baltimore Southwest

The University of Maryland BioPark is located just off I-95 in the heart of the University of Maryland’s Medical Campus in downtown Baltimore. It is an innovative campus which was developed to create partnerships between the global life sciences industry and the University of Maryland’s educational program for biomedical research. The park sits a few blocks from Baltimore’s central business district, the Inner Harbor, Camden Yards and M&T Bank Stadium. It is three miles from Johns Hopkins medical complex and a 15-minute drive to BWI Thurgood Marshall airport.

Date on Market:

2025-10-01

Hagerstown Office/Medical for Lease - Washington County

The Hub business center at 13511 label lane, is a 63,292 Sq.ft building , and sits on 4.69 acre lot. The Hub business center is centrally located in Washington county with easy access to major East coast cities like Washington DC , the Midwest, a regional Airport, two major rail providers, located less than 90 miles away from the port of Baltimore. It is a short drive to Maryland and the Pennsylvania State line. The Hub is conveniently located near restaurants, major retailers like Hagerstown Premium outlets, and the Valley mall, and several Hotels like Hampton Inn, Microtel Inn and Suites by Wyndham. Term is negotiable, reach out for further details.

Property Type:

Office

Date on Market:

2023-09-14

Gaithersburg Office for Lease

This 28,994 square foot office building is located in Montgomery County with access to I-270 and Route 355. Constructed in 1987 and zoned E-1, this two-story multi-tenant office features a variety of space sizes and 100 surface spaces for parking across 4.85 acres.

Date on Market:

2024-05-01

Mount Airy Office, Office/Medical for Lease - Carroll County

Occupied by John Hopkins, Lab Corp, Maryland Oncology and Hematology,and multi-speciality Medical Doctors. It is your chance to be neighbor with John Hopkins, Labcorp and Maryland Oncology. Easily accessible from major highways of I-70 and Route 27, this 3-floor building is located in Downtown Mt Airy. This property is ideal for medical use as it is at the centre of the $152 Million worth of healthcare market.

Date on Market:

2025-05-07

Baltimore Office/Medical for Lease - CBD Baltimore

4-story standalone building situated in the C5 zone, which allows Research and Development Laboratory Facility, is close to everything that downtown can offer. Convenient to I-83, and I-95 highways. Brand-new HVAC systems for all 4 floors. Over 12,000 SF is available with lots of natural light. The floor can be used for Offices or/and Research and Development Laboratory. 3rd floor was recently built out as a laboratory and rented by a biotech company.

Property Type:

Office

Date on Market:

2024-03-05

Rockville Office for Lease

This property was built in 2008 with renovations completed in 2024. The property sits on a 10.36-acre site with approximately 632 parking spaces. The zoning is PD (planned development) and features 24 hour access, bio-tech/lab space, fitness center, food service, property manager on site, and monument signage.

Date on Market:

2022-07-14

Rockville Flex for Lease

Date on Market:

2025-04-25

Gaithersburg Office for Lease

Flower Hill Professional Center is a dynamic addition to the area's existing amenities. Across Flower Hill Way is the Flower Hill Shopping Center anchored by Giant Food, Advance Auto Parts,and Truist Bank. Within the Professional Center, a free standing M&T Bank, Flower Hill Beer & Wine, McDonald's, and Liberty Gas Station. With its proximity to these businesses, the established shopping center, the Flower Hill Professional Center is part of an attractive complex offering a full range of services from banking to dining. This innovative office townhouse office and medical complex was built by Pettit & Griffin Builders and Developers of the Flower Hill community and the award winning Flower Hill Shopping Center. Flower Hill Professional Center is located in the heart of Flower Hill at the intersection of MD Route 124 - Woodfield Road in-between Flower Hill Way and Muncaster Mill Road in Gaithersburg, MD. Only 1.5 miles to Montgomery County Airpark Airport. Located less than 4 miles from I-370 with route to ICC-MD 200 and 4 miles from the Shady Grove Metro Station (Red Line). Additionally, there are multiple county bus stops (#57) around the property that connect to the metro and other county attractions every 20 minutes. These are just a few reasons to make Flower Hill Professional Center the site of your next office.

Date on Market:

2024-03-02

Gaithersburg Office for Lease

Flower Hill Professional Center is a dynamic addition to the area's existing amenities. Across Flower Hill Way is the Flower Hill Shopping Center anchored by Giant Food, Advance Auto Parts, and Truist Bank. Within the Professional Center, a free standing M&T Bank, Flower Hill Beer & Wine, McDonald's, and Liberty Gas Station. With its proximity to these businesses, the established shopping center, the Flower Hill Professional Center is part of an attractive complex offering a full range of services from banking to dining. This innovative office townhouse complex was built by Pettit & Griffin, Inc Builders and Developers of the Flower Hill community and the award winning Flower Hill Shopping. Flower Hill Professional Center is located in the heart of Flower Hill at the intersection of MD Route 124 - Woodfield Road in-between Flower Hill Way and Muncaster Mill Road in Gaithersburg, MD. Only 1.5 miles to Montgomery County Airpark Airport. Located less than 4 miles from I-370 with route to ICC-MD 200 and 4 miles from the Shady Grove Metro Station (Red Line). Additionally, there are multiple county bus stops (#57) around the property that connect to the metro and other county attractions every 20 minutes. These are just a few reasons to make Flower Hill Professional Center the site of your next office.

Date on Market:

2023-11-01

Gaithersburg Office for Lease

Flower Hill Professional Center is a dynamic addition to the area's existing amenities. Across Flower Hill Way is the Flower Hill Shopping Center anchored by Giant Food, Advance Auto Parts, and Truist Bank. Within the Professional Center, a free standing M&T Bank, Gentleman Jim's Restaurant & Flower Hill Beer & Wine, McDonald's, and Liberty Gas Station. With its proximity to these businesses, the established shopping center, the Flower Hill Professional Center is part of an attractive complex offering a full range of services from banking to dining. This innovative office townhouse office and medical complex was built by Pettit & Griffin Builders and Developers of the Flower Hill community and the award winning Flower Hill Shopping Center. Flower Hill Professional Center is located in the heart of Flower Hill at the intersection of MD Route 124 - Woodfield Road in-between Flower Hill Way and Muncaster Mill Road in Gaithersburg, MD. Only 1.5 miles to Montgomery County Airpark Airport. Located less than 4 miles from I-370 with route to ICC-MD 200 and 4 miles from the Shady Grove Metro Station (Red Line). Additionally, there are multiple county bus stops (#57) around the property that connect to the metro and other county attractions every 20 minutes. These are just a few reasons to make Flower Hill Professional Center the site of your next office.

Date on Market:

2025-02-03

Gaithersburg Flex for Lease - North Rockville

Gaither Business Park appeals to a wide variety of companies and organizations, including entertainment, warehouse, general office, corporate headquarters, laboratory, gym, bakery, showroom, distribution and retail. Within minutes an employee can be dining, shopping, exercising, and/or relaxing at anumber of area neighborhoods that include: Falls Grove, King Farm, Washingtonian Center, and Crown Farm.

Property Type:

Office

Date on Market:

2026-01-12

Silver Spring Multiple Space Uses for Lease - North Silver Spring/Rt 29

This office building on Lockwood Drive is conveniently located in the North Silver Spring Submarket and sits only one mile outside the Beltway. The property is also within minutes to Holy Cross Hospital, and also walking distance to shopping & restaurants. The property has usable balconies and individual after hours HVAC as well as excellent after hours access for clients patients, and visitors.

Date on Market:

2025-08-05