39 Life Science Properties for Lease in North Carolina, USA

Fuquay-Varina Industrial for Lease - Southeast Wake County

1730 Five Points Lane presents a multifaceted opportunity with an expansive direct lease available. The layout works well for a single user, but can be divided into 25,000- to 75,000-square-foot spaces for multiple tenants. It features multiple dock-level loading doors, 3-phase power, and a 20-foot clear height throughout. Additionally, there is 3,500 square feet of newly renovated office space and restrooms already in place. The space is clean, functional, and ideal for distribution, light manufacturing, or general warehouse use, with ample truck court and parking for easy circulation and loading. Strategically located at the intersection of Highways 401 and 42 in Fuquay-Varina, this property provides exceptional access to Highway 55 and Interstates 540 and 40, enabling seamless connections to Raleigh, the Research Triangle, and major regional transportation routes. The site is situated within one of Wake County’s fastest-growing submarkets, surrounded by large-scale residential and commercial development that is driving population and workforce expansion. Notable nearby projects include DR Horton’s Vaughan Park, bringing over 740 new homes and 336,000 square feet of commercial space, and Academy Village, a mixed-use project anchored by Lowes Foods with 300+ apartments and townhomes. With rapid growth, infrastructure investment, and expanding labor pools, this location provides an ideal setting for users seeking a foothold in the booming Fuquay-Varina.

Date on Market:

2025-11-03

Durham Office/Medical for Lease - North Durham

Discover the Research Triangle’s generative life science, research, and healthcare ecosystem from a highly connected perspective at Independence Park. Located at 4233 Technology Drive, Independence Park is a 22,587-square-foot, single-tenant facility comprising second-generation lab, cleanroom manufacturing, and office space with robust infrastructure and a utility yard. Independence Park is equipped to handle even the most intensive operations, such as advanced manufacturing, biotech R&D, pharmaceuticals, and more. The facility is served by a drive-in loading door with an over 20-foot clearance height, an equipment mezzanine, and a 300-kilowatt generator. Additional medical infrastructure includes water filtration, benching with outlets, emergency showers, eyewash stations, chemical storage, and ISO 7 QC labs. 4233 Technology Drive is positioned at the gateway to the Research Triangle. Duke University and its surrounding medical systems are minutes away, while proximity to Interstate 85 and Highway 501 affords quick access to Chapel Hill, RDU Airport, and Raleigh. This power market provides exceptional talent as the region saw life sciences employment increase by 38% from 2020 through 2025. Beyond convenient commutability, the immediate area is replete with essential retailers, eclectic restaurants, grocery stores, hotels, and multifamily communities, an amenity-rich environment that enhances staff lifestyles. Remedy Medical Properties is a leading owner and operator of outpatient medical real estate, delivering integrated services across investments, development, leasing, management, and strategy. We own and operate medical office properties so healthcare providers can focus on patient care. Remedy Medical Properties specializes in the leasing of medical office space and outpatient medical buildings for physicians, health systems, and medical groups nationwide. Our team works directly with providers to deliver flexible space solutions that support clinical operations, patient access, and long-term growth. Learn more at remedymed.com

Property Type:

Flex

Date on Market:

2025-06-02

Morrisville Office, Flex for Lease - RTP/RDU

Discover a Premier Commercial Opportunity in the Heart of the Raleigh-Durham Triangle! Welcome to 3300 Gateway Center Blvd, a state-of-the-art flex building designed to cater to a wide range of business needs. Whether you're a small office user, a life sciences innovator, or a logistics powerhouse, this property offers unparalleled flexibility, prime location advantages, and top-tier amenities to elevate your operations. With REGUS as a major anchor tenant, this building is the perfect environment to grow and thrive. --- Property Highlights: - Fully Sprinkled Flex Building: Offering the flexibility to configure office and/or flex space combinations to suit your business needs. - Prime Location: Centrally located in the Raleigh-Durham Triangle area, right next to RDU International Airport and off Interstate I-40. - Unique Setup: Flex spaces with access to common dock-high dock doors and wide corridors allow tenants to easily take deliveries directly to their spaces. This feature makes it ideal for warehouse, distribution, manufacturing, and light industrial tenants. - Anchor Tenant: REGUS, a leader in flexible workspace solutions, providing shared office spaces, conference rooms, and break areas. This allows flex tenants to focus on their core operations without worrying about additional office space requirements. --- Available Spaces: Space A: - Small individual offices or multiple office combinations. - Options for conference rooms or small lab spaces. - Highly configurable to meet diverse tenant requirements. Space B: - Versatile flex spaces suitable for a variety of uses including: - Lab space - Research - Distribution - Warehouse - And more. - Customizable to match tenant needs. Space C: - Two smaller flex/office spaces ideal for satellite offices or smaller entities. --- Amenities: - Common dock-high dock door with wide-rated corridors for seamless logistics. - Two large restroom facilities and showers available for all tenants, reducing overhead costs. - REGUS coworking space offering additional office spaces, conference rooms, and a break room. - Proximity to a wide variety of amenities in the surrounding area. --- Strategic Advantages: - Proximity to Tier-1 Universities: - Duke University - University of North Carolina at Chapel Hill - North Carolina State University - Access to a continuous supply of highly skilled workforce. - Zoning: - Zoned ORD (Office/Research and Development): - Supports a wide range of uses including office, institutional, research and development, light manufacturing, and more. - Designed to mitigate adverse impacts when located near residential areas. --- Ideal For: - Small offices - Distribution centers - Warehouses - Research and development (R&D) - Life science users --- Don’t miss this opportunity to secure your space in one of the most sought-after business locations in the Raleigh-Durham area!

Date on Market:

2025-07-20

Charlotte Multiple Space Uses for Lease - Airport

3400 Westinghouse Blvd is a premier infill manufacturing + distribution facility in Charlotte, North Carolina. This dynamic property comprises approximately 168,300 square feet, featuring a distribution warehouse of 90,808 square feet and a production area of approximately 51,745 square feet. The facility also features 17,524 square feet of office space, a 2,050-square-foot warehouse office, and a 3,120-square-foot maintenance shop. Designed for versatility, the building can be demised down to 25,000-square-foot spaces, each with its own entrances, loading, and office. Substantial tenant improvement allowances are available to further provide a turnkey facility for tenants. With its strategic location and modern features, the property is ideally suited for industrial tenants seeking efficiency and accessibility. Clear heights range from 30'-33' feet. The site is supported by a robust power infrastructure, including a 2,000 KVA transformer and a 1,500 KVA transformer, connected to a 23.9 KV line with a 3MW capacity and a substation located within a mile with the ability to draw additional power from. Designed for efficient loading and easy accessibility, the Westinghouse Industrial Facility includes multiple drive-in doors and dock-high doors with mechanical pit levelers, dock locks, and capable of supporting 35,000 pounds. The production area features one drive-in door, one grade-level platform, and six dock-high doors, while the distribution warehouse has two drive-in doors and 10 dock-high doors. The site also provides a well-illuminated truck court with 70 marked automobile parking spaces and a fully concrete surface for heavy-duty operations. Strategically located in Charlotte's thriving industrial corridor, the property offers excellent connectivity to major transportation routes. Westinghouse Industrial Facility is approximately 2.5 miles from Interstate 485 and 2.9 miles from Interstate 77, providing seamless access to regional and national markets. Charlotte Douglas International Airport is only 10.6 miles away, and the CSX Intermodal Terminal is within 16.5 miles, ensuring convenient air and rail freight handling. Additionally, the facility benefits from proximity to several principal seaports, including the Port of Charleston (201 miles), Port of Wilmington (208 miles), Port of Savannah (243 miles), and Port of Virginia (343 miles), enhancing its logistics capabilities. Supported by an extensive infrastructure and an exceptional network of transportation routes, the Westinghouse Industrial Facility is an ideal site for industrial and distribution operations.

Date on Market:

2026-03-19

Morrisville Office for Lease - RTP/RDU

Nestled in a vibrant Raleigh neighborhood, RDU Center I is an exceptional, multi-tenant office building with modern upgrades and convenient accessibility at 3000 RDU Center Drive. This two-story, 60,083-square-foot building comprises renovated lobbies, refreshed restrooms, and a new roof. The property features a two-story atrium entrance with a granite lobby and monumental staircase, along with a 10% core factor. Originally constructed in 1999, the property is situated in the RDU Center and is conveniently located at the intersection of Interstate 40 and Aviation Parkway. Situated on 7.99 acres in the heart of the Triangle, the property is set within a beautiful park-like setting with ample on-site parking at a 5.6/1,000 parking ratio. RDU Center I boasts unparalleled access to the Raleigh-Durham International Airport and Interstate 40, providing easy commutes and travel in and out of town. Strategically positioned at the core of the region’s dynamic life science and technology cluster, the property is in a prime Raleigh locale. Raleigh is notably the #1 IT city in the US after Silicon Valley. It is also home to three research universities, making for a highly educated workforce.

Date on Market:

2023-06-02

Charlotte Industrial for Lease - University

The Innovation Center is a prime property offering ±260,000-SF of versatile space, formerly serving as an IBM Manufacturing Facility. Located off I-85 in Charlotte, NC, the property provides excellent access to major transportation routes and is adjacent to the University Research Park, a thriving area for technology and innovation. This well-maintained facility is ideal for large-scale headquarters, research and development, or industrial operations, featuring robust power infrastructure to support demanding business needs.

Date on Market:

2025-04-14

Asheville Office for Lease - S Asheville/Royal Pines

Date on Market:

2026-02-17

Raleigh Industrial for Lease - Northeast Wake County

Date on Market:

2026-02-03

Raleigh Office/Medical for Lease - Six Forks/Falls of Neuse

Property Type:

Office

Date on Market:

2026-01-20

Raleigh Flex for Lease - Route 1

Date on Market:

2026-01-05

Charlotte Office/Medical for Lease - South/485

Located in the Toringdon development near the intersection of Copper Way and Johnston Road, this professional office/medical space offers an exceptional leasing opportunity in one of Charlotte’s most sought-after South Charlotte business corridors. This Class B two-story building delivers a contemporary environment designed to support healthcare and professional users, featuring a corner suite with ample natural light. Surrounding amenities include high-end dining, boutique services, fitness options, and retail destinations, all within a walkable setting complemented by convenient surface parking. With direct proximity to I-485 and Johnston Road, tenants enjoy simplified access to Ballantyne, SouthPark, and Uptown Charlotte. The property features a fully built-out medical configuration with treatment rooms, private offices, and reception space, providing immediate usability for specialized practices. This premier location leverages the area’s vibrant demographics, with a strong mix of residential communities, established businesses, and corporate campuses. Charlotte Douglas International Airport is approximately 25 minutes away, ensuring regional and national connectivity for clients and staff.

Property Type:

Office

Date on Market:

2025-10-24

Raleigh Flex for Lease - West Raleigh

Date on Market:

2024-10-15

Wendell Industrial for Lease - Northeast Wake County

951 Wendell Boulevard offers an excellent opportunity to occupy a well-maintained industrial facility with convenient highway connectivity in the Raleigh MSA. This versatile property comprises 106,000 square feet of flexible industrial space, ideal for conditioned manufacturing, research and development, or data center/call center use. The property also features dedicated office suites and shared common areas, including a dining area and outdoor break spaces. Up to 66,000 square feet is currently available for immediate tenant use with flexible lease terms and affordable office space solutions. The landlord is open to demising the space into smaller sections to accommodate tenant needs. Additionally, 5 to 7 acres is available for land lease at $2,500/month per acre. Building specifications include varying ceiling heights from 12 to 15 feet, and in certain areas, a drop ceiling can be removed to increase the height to 17 feet. Drive-in dock doors, bathrooms, and a separate entrance are to be added by the current landlord. Situated on an expansive 48-acre site, 951 Wendell Boulevard provides ample on-site parking and room for outdoor storage or laydown yard opportunities. The laydown yard opportunity will be sectioned off from the parking lot and land by the landlord, with tenants responsible for their own fencing. Located in the heart of the Triangle, 951 Wendell Boulevard thrives in an advantageous location with quick access to interstates, population centers, railroad intermodal, and ports. Immediate access to Interstate 87 provides seamless connections in and around town, as well as to the Northern Wake Expressway/Interstate 540. The property is positioned about 30 minutes from Raleigh-Durham International Airport (RDU) for additional air cargo servicing. The Port of Wilmington is less than three hours away for convenient transcontinental trade, one of the few Southern ports with readily available berths and storage areas for containers and general cargo.

Date on Market:

2024-03-10

Kannapolis Office/Medical for Lease - Cabarrus County

Property features renovated flooring, lights along with updated restrooms, lobby and other common areas. *Common Area Renovations Complete* -Free Ample Parking - 5.5 / 1,000 SF -Building is located on the North -Carolina Research Campus -Shell Condition. Generous TI -Allowance Available

Property Type:

Office

Date on Market:

2022-10-12

Durham Office for Lease - Downtown Durham

The Roxboro offers seamless access to Downtown Durham’s vibrant entertainment, retail, restaurants, and shopping hub within a leisurely five-minute walk. Enhanced infrastructure ensures safer and more accessible pedestrian navigation. Plus, drivers benefit from direct access to major roadways for easy commuting to and from The Roxboro.

Date on Market:

2024-09-12

Durham Flex for Lease - North Durham

1101 Hamlin Road offers an exceptional leasing opportunity within a ±341,298 SF flex/life science campus on 34.7 acres in North Durham. Multiple space configurations, heavy power availability, and a proven technical infrastructure make this property ideal for advanced manufacturing, flex R&D, life sciences, and high-tech industrial users.

Date on Market:

2026-03-12

Siler City Retail for Lease - Chatham County

Chatham Square is a well-positioned retail center in the heart of Siler City’s rapidly expanding trade area, offering exceptional visibility and accessibility along East 11th Street near US Highway 64 and Highway 421. This ±69,741 SF multi-tenant property spans 7.8 acres and features 750 feet of direct frontage, ample surface parking with 272 spaces, and a strategic location within the Raleigh-Durham-Chapel Hill metropolitan region. The center is anchored by Harbor Freight and complemented by established tenants such as PTA Thrift Shop and Countryside Collectibles, creating a strong retail mix that drives consistent traffic. Siler City is experiencing robust growth fueled by new industrial employers, the transformative Chatham Park development, and projected population increases exceeding 10% over the next five years. With daily traffic counts surpassing 20,000 vehicles and household incomes averaging more than $66,000 within a five-mile radius, Chatham Square offers retailers a rare opportunity to capture both local and regional customers. The property’s proximity to major highways ensures convenient access to Raleigh, Greensboro, and surrounding communities, making it an ideal destination for service, dining, and specialty retail concepts seeking long-term stability and growth.

Date on Market:

2025-11-19

King Office/Medical for Lease - Stokes County

This property stands out as a strategic medical office location within a premier healthcare campus. Located at 167 Moore Road, King, NC 27021, the two-story King Medical Building offers a full-floor opportunity with a 21,340-square-foot demisable first floor within Novant’s Mountainview Medical Campus. It features on-campus services like primary care, diagnostics, and comprehensive therapy, and is strategically positioned in an expanding healthcare and residential corridor. With high-visibility monument signage, generous tenant improvement allowances, and flexible terms, this is an excellent opportunity to maximize visibility and create the perfect work environment. Within a 5-mile radius, 26,727 residents with average household incomes of $89,000, and 97.1% insurance coverage ensure a solid patient base. Nearby hospitals and amenities further enhance market appeal, and the new transition of US-52 to Interstate 74 will significantly broaden access. Ideal for urgent care clinics, primary care practices, diagnostic centers, dental practices, lab testing, therapy services, and specialty physician groups, this property is primed for growing healthcare providers.

Property Type:

Office

Date on Market:

2025-11-18

Raleigh Office/Medical for Lease - Route 1

This property offers an exceptional opportunity for businesses seeking a well-located, professionally maintained space in a dynamic and accessible area. Positioned within a thriving commercial corridor, the site benefits from strong visibility, convenient access to major transportation routes, and proximity to a wide range of retail, dining, and service amenities that support both daily operations and client convenience. Designed to accommodate a variety of professional, medical, retail, or service-oriented users, the property delivers a functional layout that allows businesses to operate efficiently while maintaining a welcoming experience for employees and visitors alike. Surrounding development reflects a healthy mix of commercial activity and established neighborhoods, contributing to steady traffic patterns and a stable customer base. Tenants can take advantage of the area’s robust infrastructure, including nearby highways and public transit options, making commuting simple and expanding the potential service radius. The broader community offers a strong economic environment, supported by a diverse workforce and consistent demand driven by surrounding residential density and business growth.

Property Type:

Office

Date on Market:

2025-09-25

Durham Flex for Lease - Research Triangle

Close proximity to the Research Triangle Park and RDU International Airport.

Date on Market:

2025-09-11

Research Triangle Park Office/Medical for Lease - Research Triangle

Located at the intersection of Triangle Drive and NC-54 Highway in Research Triangle Park, North Carolina, this office and lab facility presents a premier opportunity to establish operations at the heart of one of the most innovation-driven corridors of the country. 2 Triangle Drive is a single-story, Class B building spanning approximately 31,000 square feet. Originally constructed in 1977 and extensively renovated in 2001 with a $4.1 million investment, the building features modernized biotech and lab infrastructure, 24-hour access, air conditioning, and prominent signage opportunities. It includes 135 surface parking spaces, making it ideal for tenants requiring both accessibility and specialized space. Adjacent to the property is Triangle 54, a master-planned, Class A office campus developed by The Keith Corporation and Jerico Development, designed to support innovative science and technology companies. This is just one of the numerous hubs in the Research Triangle that can help tenants develop vital professional partnerships. Central placement is another key locational advantage of 2 Triangle Drive, which aids in recruiting from the competitive workforces in Durham, Raleigh, and Chapel Hill. Employees will enjoy seamless commutes off Interstate 40 and proximity to great amenities such as Starbucks, Burn Boot Camp, Food Lion, Boxyard RTP, Brigs Restaurant, Chipotle, high-end multifamily communities, and much more.

Property Type:

Flex

Date on Market:

2025-08-29

Cary Flex for Lease

102 WOODWINDS INDUSTRIAL COURT has up to 12,000 SF for lease, featuring highly functional flex and R&D space. Industrial zoning accommodates a wide range of uses, including lab, light manufacturing, industrial services, outdoor storage, personal service businesses, office, and veterinary and kennel. Located on over an acre, the property has generous parking and prominent visibility.

Date on Market:

2025-08-05

Durham Office for Lease - Research Triangle

Newly constructed lab/R&D spec suites immediately available ranging from 6,880 RSF to 32,000 RSF. Back up power/generator, loading dock, and amenities throughout the campus.

Date on Market:

2025-07-15

Morrisville Coworking for Lease - RTP/RDU

Give Your Business a Boost in Morrisville Base your business in Morrisville, North Carolina, and enjoy flexible office space in an attractive location for offices, light industry, and hotels. Benefit from being located just north of Raleigh, North Carolina’s capital, in this suburb of the greater Raleigh MSA. Commute easily to your workspace using Interstate 40 which is on your doorstep. Welcome visiting clients at Raleigh-Durham International Airport which is under a 10-minute drive away. Whether you’re looking for a long-term home for your business or just a space to get your head down when you’re on the move, you’ll find what you need here. Spark innovation and find new opportunities to connect in this state-of-the-art office space. Bring your ideas to life in the designer workspaces and creative meeting rooms, fully equipped with superfast WiFi. Our friendly team is always on hand and happy to help should you need anything throughout the working day. Feel inspired by the hive of activity surrounding you and take a break after business meetings in our fully stocked kitchens. Relax after work by taking a stroll around one of the many beautiful lakes or parks that is near the office space. Entertain clients with some delicious food at a nearby restaurant.

Property Type:

Flex

Date on Market:

2024-09-20