49 Life Science Properties for Lease in North Carolina, USA

Raleigh Office/Medical for Lease - Route 1

This property offers an exceptional opportunity for businesses seeking a well-located, professionally maintained space in a dynamic and accessible area. Positioned within a thriving commercial corridor, the site benefits from strong visibility, convenient access to major transportation routes, and proximity to a wide range of retail, dining, and service amenities that support both daily operations and client convenience. Designed to accommodate a variety of professional, medical, retail, or service-oriented users, the property delivers a functional layout that allows businesses to operate efficiently while maintaining a welcoming experience for employees and visitors alike. Surrounding development reflects a healthy mix of commercial activity and established neighborhoods, contributing to steady traffic patterns and a stable customer base. Tenants can take advantage of the area’s robust infrastructure, including nearby highways and public transit options, making commuting simple and expanding the potential service radius. The broader community offers a strong economic environment, supported by a diverse workforce and consistent demand driven by surrounding residential density and business growth.

Property Type:

Office

Date on Market:

2025-09-25

Durham Flex for Lease - Research Triangle

Close proximity to the Research Triangle Park and RDU International Airport.

Date on Market:

2025-09-11

Holly Springs Industrial for Lease - Southwest Wake County

• Ability to add a mezzanine (up to 50% of floorplate) or a second story (up to 100% floorplate) to accommodate lab, office or equipment with a 16 to 20 ft. clear height remaining on the first floor • Leaving out a slab-on-grade to allow for utility coordination by end user • Dual entries to allow for multi-entry or multi-tenant opportunities

Date on Market:

2025-08-14

Holly Springs Industrial for Lease - Southwest Wake County

Date on Market:

2025-08-14

Cary Flex for Lease

102 WOODWINDS INDUSTRIAL COURT has up to 12,000 SF for lease, featuring highly functional flex and R&D space. Industrial zoning accommodates a wide range of uses, including lab, light manufacturing, industrial services, outdoor storage, personal service businesses, office, and veterinary and kennel. Located on over an acre, the property has generous parking and prominent visibility.

Date on Market:

2025-08-05

Morrisville Industrial for Lease - RTP/RDU

74,163 square foot industrial building built in 1990 located off of Pleasant Groove Church Rd.

Date on Market:

2023-10-13

Durham Office/Retail, Retail for Lease - Downtown Durham

Date on Market:

2025-11-04

Morrisville Coworking for Lease - RTP/RDU

Give Your Business a Boost in Morrisville Base your business in Morrisville, North Carolina, and enjoy flexible office space in an attractive location for offices, light industry, and hotels. Benefit from being located just north of Raleigh, North Carolina’s capital, in this suburb of the greater Raleigh MSA. Commute easily to your workspace using Interstate 40 which is on your doorstep. Welcome visiting clients at Raleigh-Durham International Airport which is under a 10-minute drive away. Whether you’re looking for a long-term home for your business or just a space to get your head down when you’re on the move, you’ll find what you need here. Spark innovation and find new opportunities to connect in this state-of-the-art office space. Bring your ideas to life in the designer workspaces and creative meeting rooms, fully equipped with superfast WiFi. Our friendly team is always on hand and happy to help should you need anything throughout the working day. Feel inspired by the hive of activity surrounding you and take a break after business meetings in our fully stocked kitchens. Relax after work by taking a stroll around one of the many beautiful lakes or parks that is near the office space. Entertain clients with some delicious food at a nearby restaurant.

Property Type:

Flex

Date on Market:

2024-09-20

Wake Forest Multiple Space Uses for Lease - Route 1

New 30-acre business community located along Star Road (US 1) near South Main Street (New Falls of Neuse Road) Conveniently located near a variety of business amenities, shopping, entertainment and restaurants, as well as a diverse residential area featuring both mature and new communities.

Date on Market:

2024-07-09

Morrisville Office/Medical for Lease - RTP/RDU

Explore the epitome of healthcare real estate situated in the heart of the Cary-Morrisville Area, directly on Davis Dr. Our state-of-the-art, 20,020 sqft Class A medical-grade building is a testament to unparalleled sophistication, featuring hospital-grade elevators and HVAC systems that guarantee a premier medical environment. Strategically located along the bustling 6-lane Davis Dr corridor and within a mile of the new upcoming Apple campus, this facility offers unparalleled visibility and accessibility, making it a cornerstone for healthcare excellence in one of Cary's most sought-after regions, adjacent to RTP. Surrounded by a high-density residential area, this building beckons healthcare professionals with its diverse tenant mix, encompassing Urgent Care, Primary Care, Orthopedics, Physical Therapy and other specialized medical services. Embrace the opportunity to join a thriving community of healthcare practitioners in a facility meticulously designed for success. Elevate your practice in a space that not only meets the current standards but also aligns seamlessly with the future of healthcare.

Property Type:

Office

Date on Market:

2025-02-01

Research Triangle Park Flex for Lease - Research Triangle

Longfellow's Via Labs Purpose-Built Class A Lab Building is comprised of 266,480 rentable square feet and is located at the main-on-main RTP intersection of I-40 and Davis Drive with unparalleled visibility from I-40 with over 170,000 VPD. Via Labs at Hub RTP offers a highly walkable environment, offering many features within the campus including a high-end hotel, conference space, retail, 16-acres of green space, bicycle storage, and over 2,300 multifamily units, with full access to all HUB RTP has to offer including the existing Boxyard Retail.

Date on Market:

2023-03-17

Cary Office for Lease

Date on Market:

2023-01-27

Morrisville Flex for Lease - RTP/RDU

Date on Market:

2023-01-27

Raleigh Office/Medical for Lease - Six Forks/Falls of Neuse

8300 Health Park offers adaptable outpatient medical suites supported by space-planning services and a generous tenant improvement allowance. This is ideal for treatment rooms, surgical practices, dental work, lab testing, and a variety of healthcare-related users. The campus features an on-site café, a full-service pharmacy, and a state-of-the-art fitness facility with an indoor pool, basketball courts, and private showers. Outdoors, tenants enjoy a lakeside patio and 0.75 miles of walking trails that enhance the workplace experience. With more than four parking spaces per 1,000 SF, an attached covered garage, and easily accessible surface parking, the property ensures smooth daily access for both providers and patients. This site is surrounded by amenities to live, work, and play. Within a 5-mile radius, there are more than 30 eclectic restaurants, recreational amenities like gyms and country clubs, and name-brand stores like Whole Foods, Target, Dick’s Sporting Goods, and Home Depot. 8300 Health Park affords streamlined access to key arterial highways, including Interstate 540 and Route 50, and its central location places tenants within 16 minutes of three major hospitals and RDU International Airport. Offering convenience, flexibility, and a strong amenity package, 8300 Health Park stands out as a premier healthcare setting in the Raleigh market. Remedy Medical Properties is a leading owner and operator of outpatient medical real estate, delivering integrated services across investments, development, leasing, management, and strategy. We own and operate medical office properties so healthcare providers can focus on patient care. Remedy specializes in the leasing of medical office space and outpatient medical buildings for physicians, health systems, and medical groups nationwide. Our team works directly with providers to deliver flexible space solutions that support clinical operations, patient access, and long-term growth. Learn more at remedymed.com

Property Type:

Office

Date on Market:

2024-05-21

Durham Flex for Lease - Research Triangle

Date on Market:

2026-01-22

Winston-Salem Office for Lease - Winston-Salem CBD

Located in the South West Corner of the Innovation Quarter, this converted tobacco factory offers hard wood floors, high ceilings and exposed masonry finishes. This building was used for the manufacturing of “Prince Albert Pipe Tobacco” and has now been converted for office, lab, and residential use. The building is predominantly occupied by biotech companies, and features a freight elevator and loading docks. There are a variety of office sizes and layouts available.

Date on Market:

2025-08-25

Raleigh Office for Lease - West Raleigh

1791 Varsity Drive is located in North Carolina State University’s world-class Centennial Campus, one of Raleigh-Durham’s premier office and research parks. Situated just south of NC State’s main campus and two miles west of Downtown Raleigh, the property benefits from an amenity-rich location just south of NC State’s main campus. Centennial Campus is a 1,314-acre research park owned and operated by NC State. The campus is home to more than 70 corporate, governmental and non-profit “partners,” along with 75 N.C. State research centers, institutes and departmental units and numerous colleges. In addition to the buildings and research centers, Centennial Campus also contains public walkways, a fishing pier and lake, game fields and an 18-hole golf course.

Date on Market:

2024-09-26

Morrisville Office, Flex for Lease - Research Triangle

Triangle LIFE is a major hub for science companies in North Carolina’s Research Triangle, connecting people, place and purpose in an amenity-rich atmosphere. Triangle LIFE centers around the life sciences and the people devoted to them. It’s a community of scientists in a shared ecosystem of energy and synergy where proximity is key. Everything works together to make working here remarkable. This is North Carolina’s legendary Research Triangle, the intellectual and creative intersection of three top universities. Raleigh Durham International Airport is just minutes away. Centrally located within this dynamic area, Triangle LIFE is a 100-acre oasis for life science companies on the pulse of what’s happening now and with the ability to anticipate what’s next.

Date on Market:

2026-01-21

Morrisville Flex for Lease - RTP/RDU

This Class A life science campus will offer four 160,000 SF mid-rise buildings and combine state-of-the-art lab space with unmatched amenities provided by Elevate, Longfellow’s proprietary tenant experience and hospitality program. Strategically situated in Research Triangle Park with proximity to surrounding lab and office campuses and offers easy access to major thoroughfares, nearby restaurant and retail amenities, and RDU International Airport.

Date on Market:

2021-03-11

Durham Office for Lease - Research Triangle

Patriot Science Center is a life science facility with second generation lab, vivarium and office space previously occupied by Pfizer, Laird, and Argos. Building systems are separated by suite.

Property Type:

Flex

Date on Market:

2020-06-15

Durham Flex for Lease - Research Triangle

Longfellow’s proprietary tenant experience and hospitality program, Elevate, curates events, programming and services exclusively for our tenant partners.

Date on Market:

2021-07-15

Holly Springs Land for Lease - Southwest Wake County

Raw, level land located in the heart of Holly Springs, NC. Property is at a signalized intersection and boasts over 1,000 feet of frontage on Avent Ferry Road.

Property Subtype:

Commercial

Date on Market:

2025-09-04

Research Triangle Pk Flex for Lease - Research Triangle

The building provides exceptional amenities such as an on-site fitness center, conference facilities, and collaborative workstations, fostering a dynamic and productive environment. Located minutes from major highways and leading universities, the property ensures seamless connectivity to Raleigh, Durham, and Chapel Hill, making it ideal for life sciences, biotech, and technology firms. Immediate availability and negotiable rental terms make this an outstanding choice for companies looking to scale in one of the nation’s most innovative regions.

Date on Market:

2025-09-02

Durham Office for Lease - Downtown Durham

Located in Downtown Durham in walking proximity to lots of restaurants and retail options such as Bull McCabe’s, Dram and Draught, Mateo Bar de Tapas, and more.

Property Type:

Flex

Date on Market:

2025-07-11