47 Life Science Properties for Lease in New York, USA

New York Office for Lease - Columbus Circle

525 W 57th Street is a future-forward professional office and lab building on Manhattan's West Side. The 500,000-square-foot building rises 10 floors and boasts the substantial characteristics and infrastructure to support tenant growth and creativity. Property features include M1-5 zoning for office, life science, and light manufacturing use, floors with a live load capacity of 120 pounds per square foot, immersive 12-foot, 1-inch to 15-foot, 10-inch ceiling heights, natural light-filled interiors from large windows, and more. Tenants and guests have access to three lobbies (two on 57th Street and one on 58th Street). The two lobbies on 57th Street were recently renovated. One of the lobbies was designed by Dan Shannon and MdeAS and features a frieze art sculpture by Stephen Doyle. Open and efficient side-core floor plates allow flexibility for layout and design. Full and partial floors are immediately available for occupancy and can be customized to meet business needs. Situated within walking distance of Columbus Circle, 525 West 57th Street is surrounded by the city's finest dining and entertainment. 521 W 57th Street tenants enjoy zero initiation fees and reduced membership rates to the Mercedes Club, a luxury all-inclusive gym and health club conveniently located at 550 West 54th Street. Mass transit users benefit from convenient access to the 59th Street – Columbus Circle Subway station for hassle-free commuting to and from the property. Surrounding amenities like Hudson Market, Lincoln Center, Central Park, and the Shops at Columbus Circle are accessible within moments.

Date on Market:

2026-04-24

Pearl River Multiple Space Uses for Lease - Orangetown

Hudson Valley iCampus is a 207-acre mixed-use campus at 401 N. Middletown Road in Pearl River, New York. Hudson Valley iCampus offers highly sought-after laboratory, office and GMP space in a campus setting built to support growth. Designed for both emerging companies and established industry leaders, it gives tenants access to specialized, move-in-ready space without the time and expense of ground-up development. A major advantage is the on-site 23-megawatt Central Utility Plant, which provides reliable, cost-effective electricity, steam and chilled water, backed by redundant public systems. With a prestigious roster of tenants that includes Pfizer, Sanofi, Momentive Performance Materials, Olaplex, RK Pharma and others, the campus delivers a strong business environment shaped by innovation, proven infrastructure and long-term credibility. With a legacy of groundbreaking vaccine development and a reputation as one of the top destinations in the New York tri-state area for life sciences, biotech, manufacturing and warehouse users, Hudson Valley iCampus stands out as a compelling choice for companies seeking room to operate and grow. Hudson Valley iCampus is strategically positioned in the Hudson Valley, offering businesses convenient access to dining, shopping, hotels and entertainment, along with strong regional connectivity. Located within 24 miles of Manhattan, the campus provides easy access to train stations, the Mario M. Cuomo Bridge and the New York State Thruway, making it highly accessible for employees, clients and operations. Situated within the heart of a growing biotech megaregion, the property gives tenants direct access to a highly skilled labor pool and close proximity to other major life science hubs. Its location near downtown Pearl River and the retail, dining and hospitality options in Nanuet further enhances the appeal for companies seeking both convenience and a well-connected business environment.

Date on Market:

2026-04-21

Troy Office for Lease - Downtown Troy

The Gurley Building, located at 514 Fulton Street, is a landmark property in Troy, New York. Formerly used for engineering, research, and development, the four-story professional building contains 57,900 square feet and is listed on the National Registry of Historic Places. A stunning interior atrium courtyard, high exposed ceilings, grand arched windows overlooking inspiring city views, and plank wood floors add unparalleled charm and nod to the property’s industrial past. Tenants also benefit from secure intercom front entry, reliable and on-site property management, and access to ample off-street parking in adjacent lots. The third floor is available for lease and is sub-dividable with flexible options for complimentary custom space planning. Experience an open floor plan loft with over 15 private offices, a conference room, and richly textured brick walls. This space is ideal for creative thinkers and professional businesses. Situated in the heart of Downtown Troy, the Gurley Building is within walking distance of restaurants, hotels, shops and trendy boutiques, and many other local amenities. Reach the campuses of Rensselaer Polytechnic Institute (RPI) and Russell Sage College within minutes and enjoy easy access to all major highways: I-87, I-90, and I-787. The Gurley Building is a perfect destination for all creative professionals!

Date on Market:

2026-04-03

Albany Office, Office/Medical for Lease - E Outer Albany County

Computer Park, located just off Wolf Road in Colonie, New York, offers executive and professional office space ranging from 258 to 3,305 square feet within a thoughtfully designed 11-building office campus. From sleek executive suites to expansive full-floor layouts, the property delivers flexible configurations that accommodate solo entrepreneurs, growing teams, and established businesses. All offices enjoy bright interiors with ample natural light, while select suites offer private mailboxes, storage options, shared or private conference rooms, kitchenettes, waiting areas, skylights, and French glass doors. All-inclusive leasing packages include parking, property maintenance, taxes, snow removal, common area maintenance, and basic janitorial services, with utilities also available for inclusion. Supported by on-site professional management and 24/7 secure access, Computer Park presents a turnkey solution that allows businesses to focus on productivity and growth in a prestigious, park-like setting. Professionally maintained year-round, Computer Park blends function and curb appeal through landscaped grounds that create a welcoming environment for employees and visitors. Furnished and unfurnished suites, customizable layouts, and a wide range of floor plans support diverse work styles, from client-facing professional services to collaborative office users. A 70-space parking lot, on-campus EV charging stations, immediate access to the Albany bus line, and responsive on-site management enhance daily convenience and operational efficiency. Situated minutes from Interstates 87 and 90, Computer Park delivers seamless regional connectivity via the Northway, providing quick drives to Downtown Albany, Troy, Schenectady, and Saratoga Springs, as well as a short commute to Albany International Airport. The Wolf Road corridor anchors one of the Capital Region’s strongest commercial districts, surrounded by prominent retailers and dining options, including Outback Steakhouse, LongHorn Steakhouse, Ruth’s Chris Steak House, Nothing Bundt Cakes, McDonald’s, Chipotle, and many more within a half-mile. Computer Park is a prime opportunity to lease flexible, professionally managed office space designed to support long-term business success in a thriving market.

Date on Market:

2026-05-14

Orangeburg Office, Industrial for Lease - Orangetown

Position your business in one of Orangeburg’s most versatile and strategically located commercial properties. 560 Route 303 offers modern, flexible office space ranging from 1,000 SF to 20,000 SF, ideal for professional offices, creative teams, technology firms, medical users, administrative headquarters, and growing businesses seeking a highly accessible Rockland County location. The property features an abundance of natural light throughout the office spaces, creating a bright and productive work environment for employees and clients alike. The building is home to several established corporate companies, providing tenants with a professional and business-oriented atmosphere. The property currently underwent upgrades and improvements, creating a refreshed and modern environment for tenants. Spaces can be customized to accommodate a variety of layouts, from private executive offices and collaborative open workspaces to conference rooms and client-facing operations. For companies that require both office and industrial functionality. In addition to the office availability, the property also offers industrial and warehouse space options. Conveniently located directly on Route 303 with immediate access to the Palisades Parkway, I-87, I-287, and the New Jersey border, the property offers excellent regional connectivity for employees, clients, and commuters.

Date on Market:

2026-05-18

Buffalo Office/Medical for Lease - Buffalo CBD

Property Type:

Office

Date on Market:

2026-01-14

Buffalo Office, Flex for Lease - North

Date on Market:

2025-12-02

Maspeth Industrial for Lease - Central Queens

Now available for lease at $30 PSF NNN, 48-23 55th Avenue delivers a ready-to-occupy flex warehouse solution in one of NYC’s most connected industrial zones. This single-story facility offers ±18,800 SF of warehouse space, ±11,600 SF of lab space, and ±4,500 SF of office space, ideal for logistics, light manufacturing, or specialized medical operations. The property’s previous use as a sterile IV infusion lab means it includes unique infrastructure that can be retained or retrofitted for general industrial use. Tenants benefit from two oversized interior loading docks, 16’ clear height, and 18 dedicated parking spaces. The site’s proximity to the BQE and LIE interchange ensures efficient distribution across the Tri-State area, while nearby access to JFK, LaGuardia, and Newark airports supports regional and national logistics. Surrounded by high-credit tenants such as FedEx, UPS, and Tesla, this location offers both prestige and performance. Recent renovations, including a new roof and upgraded systems, make this a plug-and-play solution for industrial users seeking speed-to-market.

Date on Market:

2025-10-09

Chester Retail for Lease - Monroe

Discover this well-maintained 24/7 full-access Class B commercial building, perfectly blending functional lab space with modern executive offices. The main floor is primarily dedicated to lab space, including a critical clean room. Adjacent to the clean room, you'll find an unfinished/industrial-style area with open ceilings, ideal for specialized operations, complemented by a convenient small loading dock. Upstairs, the executive office space provides a professional environment. The full finished basement adds significant utility with a break room, multiple offices, and a hallway with lockers, offering ample support and storage. Traffic counts around the property are: 12,814 AADT on Brookside Ave. and 51,097 on NY-17 - Exit / Entrance ramps are around the corner - Very easy access to the highway Offered on a Triple Net lease basis, tenant pays rent and all operating expenses. Listing may not itemize all expenses.

Date on Market:

2025-07-15

Victor Office, Flex for Lease - Southeast

Premier Office/Flex Space in Omnitech Business Park Positioned at the west side of the highly regarded Omnitech Business Park, Omnitech Place offers an exceptional opportunity for office or flex space users seeking convenience, quality, and flexibility. The building benefits from direct access off Phillips Road, providing easy ingress and egress for employees, clients, and deliveries. This single-story building is impeccably maintained and features mature landscaping, a clean, professional façade, and a layout that supports a wide range of uses—from traditional office setups to light industrial or hybrid configurations. The property is subdivided into four suites, two of which are currently leased by small tenants. The remaining vacancy includes the former Waste Harmonics space, the largest available unit in the complex, which is new to the market and well-positioned for a quick lease-up given its high visibility and layout flexibility. Property Highlights: Located in Victor, NY, a growing commercial hub just south of Main Street Fishers and Route 96 Minutes from I-490 and the New York State Thruway (I-90), allowing for regional connectivity Well-maintained interior and exterior, with attractive curb appeal and ample natural light Ample parking, ideal for office or light industrial users Positioned in a professional campus setting with a mix of tech, medical, and service tenants Opportunity to occupy larger contiguous space or lease smaller suites as needed Omnitech Business Park is known for its modern construction, excellent accessibility, and flexible floor plans that attract a diverse tenant mix. The 7620 building, in particular, offers strong upside for companies seeking move-in-ready space or those looking to customize their next headquarters or satellite office. 7620 Omnitech Drive – Flexible Suite Options with Loading 7620 Omnitech offers multiple leasing opportunities, including: 12,188 SF 17,426 SF (with a loading dock) 2,243 SF The 12,188 SF and 17,426 SF suites are adjacent and can be combined for a total of up to 29,614 SF of contiguous space. Ideal for office, flex, or light industrial users seeking functionality and scale in a modern business park setting. Omnitech Business Park – Future Development Opportunity The Omnitech Business Park offers over 22 acres of land with significant development potential. The site can accommodate up to four new buildings, or a custom build ranging from 30,000 SF to 150,000 SF, subject to Town approval. Ideal for office, flex, or light industrial users seeking scalable, modern space in a strategic Finger Lakes location.

Date on Market:

2026-04-30

Suffern Office for Lease - Ramapo

Amazing Opportunity! This highly visible office space is located at the beginning of Suffern's downtown, directly across from what was formerly Avon's Research and Development building. Office setup maintains large conference room, large waiting / reception area, two private offices, one work space and private bathroom. Large, attached parking lot offers convenience for your clientele and staff. Wired for high speed internet. Front and rear entrances to the building. Lease is offered $3,700 /month Modified Gross; electric and hot water included.

Date on Market:

2025-03-13

Plainview Office/Medical, Flex for Lease - Eastern Nassau

Date on Market:

2026-04-06

Islandia Industrial for Lease - Western Suffolk

3100-3124 Express Drive South is a 36,000 SF commercial multi-tenant building located directly on the LIE Southern Service Road and Exit 57 and Veterans Memorial Highway. The location has direct frontage from the Service road and partial LIE visibility. The building is fully landscaped and well maintained with a sister building sitting just South on the site. 3100 Express drive South is located on the edge of the village of Islandia - the intersection of Veterans Memorial Highway and the Long Island Expressway. This location allows for simplified trucking and commuting with proximity to Long Island's major highways (East-West) and Vets highway running Northwest- Southeast.

Date on Market:

2026-06-22

Yonkers Office, Office/Retail for Lease - Southwest

The property is located at the top of Southwest Executive Office Park, in the northeast section of the City, at the border of Hastings-on-Hudson.

Date on Market:

2024-03-13

Great Neck Office/Medical for Lease - Western Nassau

Private suites available in a three story, ideal commercial property. It has recently undergone remodeling and renovation, such as New Boiler, Roof, hallways with New paint, Carpet and LED Lighting. Ensuring a comfortable and efficient space for tenants. For additional tenants’ convenience, it also features private bathrooms for all suite, parking spot and elevator. Situated in the heart of Great Neck Plaza,it is highly desirable due to its close proximity to town shopping, banks, post offices, restaurants, parks and LIRR (20 min. Ride to Manhattan) making it an popular spot for any kind of business.

Property Type:

Office

Date on Market:

2025-12-02

Uniondale Office/Medical for Lease - Central Nassau

108,908 SF office building with life science lab space already incorporated.

Property Type:

Flex

Date on Market:

2023-05-02

Forest Hills Office/Medical for Lease - Central Queens

Prime Offices space for lease in the most busiest hub of Austin Street located next to Major national stores and Restaurants such as Target, Eddie Baur, GAP, Starbucks, TGIF and more... This store is located just two blocks off Continental Ave and Queens Blvd with only two blocks to subways, and LIRR. This space is ideal for and is currently used as a long time established MD office however, other office use is possible as well. Austin street is known for its strip of many popular retail businesses, restaurants, gyms and more..

Property Type:

Retail

Date on Market:

2025-05-19

Port Chester Flex for Lease - East I-287 Corridor

3rd Floor Loft Space - Open Floor Plan Multi use flex space - ideal for R & D, office, assembly, studio and/or production, light storage, wellness space, low impact recreational use, small scale fabrication, . No residential or food. Metro North RR across the street from the building. Bus service directly in front of the building Located in the heart of the Central Business District. Dining and entertainment center. Available immediately Light freight elevator to the premises space.

Property Type:

Office

Date on Market:

2026-04-21

Woodbury Office for Lease - Eastern Nassau

All utilities are separately metered. This office is located in a park-like setting. There is no Loss Factor. The LIE, RTE 135, Northern State Parkway, & Jericho Turnpike are close by. The space is in move in condition, and furniture is available.

Date on Market:

2021-07-14

Menands Office for Lease - E Outer Albany County

Riverview Innovation Center is a 977,780 SF property that has undergone significant renovations to offer a dynamic blend of office and industrial space. Featuring modern finishes, thoughtfully designed common areas, and premium amenities, the building delivers a workplace environment that enhances productivity and collaboration. With flexible spaces available across eight floors, suites of varying sizes can accommodate a range of business needs and are supported by competitive tenant improvement packages, allowing for customized, build-to-suit solutions. Ideally located with excellent accessibility to Downtown Albany, this property is the perfect setting for businesses seeking a modern, versatile, and strategically positioned workplace.

Date on Market:

2024-12-13

Brewster Village Office, Office/Medical for Lease - Brewster

Date on Market:

2026-01-13

Holbrook Industrial for Lease - Central Suffolk

Sherwood Corporate Center has a campus environment with direct access to Sunrise Highway, Veterans Memorial Highway and Nicolls Road and conveniently situated just 2 miles from the LIE. Ideal for Warehouse and Distribution, Light Manufacturing or Research and Development Unit 8: 8,840 SF Flexible Layout 4 Bathrooms Two 14' Drive-In Doors 200 AMPS 3 Phase Electric Service LED Lighting

Date on Market:

2023-12-04

Jamestown Office for Lease

The West Gate Building is centrally located in Jamestown’s business district. Condé Nast Traveler has called “one of the best museums in the country” and which attracts 100,000 people a year, and a five minute walk to the Northwest Ice Arena which draws 250,000 people a year. The West Gate Building is the only office building in the downtown business district with ample onsite parking (all of which is unmetered), and is an ideal location for doing business in Jamestown.

Date on Market:

2026-02-01

Port Washington Office/Medical for Lease - Western Nassau

Turnkey flex offie space ideal for a variety of uses

Property Type:

Flex

Date on Market:

2026-05-21