102 Life Science Properties for Lease in Pennsylvania, USA

Conshohocken Office for Lease

Conshohocken is just a short drive from downtown Philadelphia, making it ideal for commuters who work in the city. The property is easily accessible via Interstate 476 and Route 23.

Date on Market:

2025-07-31

Easton Office/Medical for Lease - Lehigh Valley

Excellent opportunity to access turnkey medical office space in growing suburb of Easton, PA. Choose from varying sizes of office, medical, professional services space on 4 floors. Or bring your growing surgery practice to the turn-key 3rd Floor 10,000 sq. ft. ideal for orthopedic, joint replacement and other out-patient surgeries.

Property Type:

Office

Date on Market:

2023-08-28

York Industrial for Lease - York County

Industrial space available in the Acco Business Park at 75 Acco Drive in York, PA. This business park, located just off S. Queen St./Route 74, offers easy access to Interstate-83. Warehouse/flex space complete with loading docks and drive-in doors. Ideal location for contractors, wholesalers and warehouse uses. Space available located in either Building A or B. Suite A 3 is 3,000 SF with storefront windows and a single loading dock to the rear. Suite B 8-9 is 10,950 SF, and has four (4) loading docks and two (2) drive-in doors.

Date on Market:

2026-03-13

Pittsburgh Office for Lease - East End

Date on Market:

2024-12-04

Lancaster Flex for Lease - Lancaster County

A 32,143+/- SF, state-of-the art lab and R&D property with 9,650+/- SF of air-conditioned lab space with 10' ceilings, a 16,825+/- SF plant warehouse and 5,666+/- SF of office. The suite features four loading docks (2 with levelers) and two drive in doors.

Date on Market:

2022-09-01

Norristown Office, Flex for Lease - Norristown/Valley Forge

Date on Market:

2026-03-16

Plymouth Meeting Flex, Industrial for Lease - Norristown/Valley Forge

The 435 School Lane office building located in Plymouth Meeting, a prime location offering immediate access to 276/PA Turnpike. Situated on a sprawling 10.60-acre lot, this property provides a versatile space suitable for flex, lab, and industrial use. The office building boasts numerous features designed to meet the needs of modern businesses. With private entrances and two convenient loading docks, it ensures seamless operations and efficient logistics. Abundant parking is available on-site, ensuring convenience for employees. The strategic location of this property is a major advantage, as it offers a quick and easy commute from Delaware, New Jersey, and the Lehigh Valley, making it an ideal choice for businesses with regional operations. Additionally, the surrounding area provides a wealth of amenities, including shopping centers, dining establishments, and hotels, ensuring convenience for employees and clients.

Date on Market:

2021-06-02

East Norriton Township Office for Lease - Norristown/Valley Forge

Norriton Business Campus is strategically located on the Germantown Pike corridor in East Norriton Township. Join several other Office, Commercial and Industrial space in the beautifully landscaped park-like setting of Norriton Business Campus, complete with walking trails to enjoy the sunshine. The campus is one mile from Einstein Medical Center, and an array of restaurants, retail, personal, professional and medical services in close vicinity. Norriton Business Campus provides accessibility to all major markets in the Tri-State area and is a ten-minute drive from the Mid-County/Plymouth Meeting Interchange of the PA Turnpike (I-276), Northeast Extension, and Blue Route (I-476), Schuylkill Expressway (I-76) providing access to Philadelphia, New Jersey, and New York.

Date on Market:

2022-03-17

Canonsburg Office for Lease - Washington County

4 Grandview Circle is a multi-tenant, two-story office building located in Canonsburg. The property offers an abundance of free parking.

Date on Market:

2022-05-16

Plymouth Meeting Flex for Lease - Plymouth Mtg/Blue Bell

Located at the key regional interchange of I-476 (Blue Route & NE Extension) and I-276 (PA Turnpike) and minutes from I-76 (Schuylkill Expressway) and Rt 202. Excellent visibility from Blue Route (I-476) and PA Turnpike (I-276). 100% climate-controlled flex / industrial space with new tailgate and drive-in loading docks. Office space built to suit. 16’4" clear height. Light industrial zoning, allows lab/ R&D, manufacturing, warehouse. Abundant amenities nearby including Plymouth Meeting Mall (Whole Foods, PF Chang's, Redstone Grill), two hotels in walking distance, restaurants, and Metroplex Shopping Center (Target, Giant, Best Buy, Starbucks). Existing tenants include Donnelly's HVAC, Globus Medical and H.C. Nye, Co.

Date on Market:

2025-12-22

Butler Office for Lease - Butler County

Three floor medical office building adjacent to Butler Memorial Hospital. Minutes from the heart of Butler and Route 8. 63 on-site free parking spaces with 5 handicap-accessible spaces and additional free parking in the adjacent hospital parking garage.

Date on Market:

2020-09-30

Philadelphia Office for Lease - Independence Hall

Designed, engineered and built to carry the weight and withstand vibrations of massive printing presses, the iconic Curtis is poised to become a world class conversion and meet the comprehensive space needs of the surging life science community. Located within America's most historic mile, this Philadelphia Landmark is as relevant today as it was the day it was built. No other building in Philadelphia can offer the base features required for speed to market, as can The Curtis. The Curtis has: 220 lb floor loads, dual 13,200 v electric feeds, back- up generators, excess shaft space for exhaust, circulating chilled water throughout, two (2) freight elevators 4,500 and 5,500 lbs capacity, four (4) fresh air intakes per floor, 12 story atrium providing double the amount of natural light, 14' 6'' ceiling heights and last but not least, is the permanent home of "The Dream Garden" the 100,000 piece glass mural designed by Mayfield Parrish and built by Tiffany Studios.

Date on Market:

2023-03-02

Pittsburgh Office for Lease - Parkway West Corridor

Property Type:

Flex

Date on Market:

2020-04-14

Bethlehem Office/Medical for Lease - Lehigh Valley

Situated in the heart of the thriving LEHIGH Valley Industrial Park with It’s striking architecture and trade mark Rose Glass make this building one of the most recognizable in the entire industrial park. With great access to all major highways and thruways such as 22 ,78 ,33. Near Fedex UPS and the LehighValley Post Office this ideal location offers many amenities and a distinct style that makes this building a true stand out. The building is serviced by a large private parking lot and maintained to a high degree. Suite 200 is an upscale amenity rich office space situated in the heart of the thriving Lehigh Valley. FULLY FIT OUT LAB SPACE WITH MULTIPLE WORK AREAS AND SYSTEMS IN PLACE has access to executive style, restrooms, and common areas.

Property Type:

Flex

Date on Market:

2025-01-10

Philadelphia Office, Office/Medical for Lease - Market Street East

156,000 Square foot, 15 story office building in the heart of Center City with traditional, creative and medical office options available.

Date on Market:

2022-05-17

Erie Office, Office/Retail for Lease - Outlying Erie County

Knowledge Park is designed to be a research and development hub for forward-thinking, knowledge-driven businesses. It partners with companies seeking to innovate with the talent and resources of one of the country’s leading research universities. You’ll have infrastructure, property management, security and support services combined with talent and technology resources. It’s a unique environment for innovation.

Date on Market:

2023-06-28

Horsham Township Flex for Lease - Horsham/Willow Grove

The property at 103 – 109 Gibraltar Road in Horsham, PA, is a flex/industrial building offering 18,000 SF of space. It is located near the Willow Grove/Horsham Exit 343 of the Pennsylvania Turnpike and provides access to Routes 611 and 63. The site is served by SEPTA bus routes and is in proximity to retail, restaurants, fitness centers, and daycare facilities. The building includes loading docks, van-height doors, and office space.

Date on Market:

2026-04-03

Easton Medical for Lease - Lehigh Valley

Large private parking, public water/sewer, and ADA access. The current configuration includes reception/waiting, multiple exam or office rooms, storage, closets, chart filing, employee break room, private restroom, dedicated accessible parking, and ramp-access entry from Ferry Street. Located near St. Luke’s – Easton Hospital Campus with direct access to Route 22 and I-78, the property is well suited for outpatient medical, specialty clinic, counseling, and healthcare administrative users. 120KW / 400+ amp three-phase power and T.I. opportunities provide additional flexibility for tenancy requirements. 4,764 SF standalone medical office for lease 14-room existing clinical layout 4 ADA restrooms Large private parking field with marked accessible spaces Reception/waiting plus multiple exam or office rooms Storage, closets, chart filing, employee break room, and private restroom ADA access, dedicated accessible parking, and ramp-access entry Public water/sewer 120KW / 400+ amp three-phase power Near St. Luke’s – Easton Hospital Campus with Route 22 / I-78 access Potential uses: outpatient medical, specialty clinic, counseling / admin healthcare 2100 Ferry Street is a standalone medical office building positioned for healthcare, behavioral health, and other outpatient users seeking functional, existing infrastructure in a hospital-oriented Easton location. The property totals 4,764 square feet and is currently configured with a 14-room clinical layout, 4 ADA restrooms, large private parking, and public water/sewer. The asset’s standalone footprint and dedicated on-site parking differentiate it from conventional multi-tenant office product and support direct leasing to professional medical and outpatient users requiring operational control, visibility, and accessible entry. The interior program is already structured for medical occupancy. Existing improvements include reception and waiting, multiple exam or office rooms, storage, closets, chart filing, employee break room, private restroom, ADA access, and dedicated accessible parking. The floor plan is arranged with 14 rooms along central corridors and reception/support functions near the core, providing a layout compatible with appointment-based clinical operations, counseling practices, specialty outpatient care, and healthcare administrative uses with patient interface. Site access and circulation are core leasing advantages. The property includes ramp access from Ferry Street, marked accessible parking, and a private parking field. These features support streamlined patient and staff access while reducing the operational constraints typically associated with converted office inventory. The building also includes 120KW / 400+ amp three-phase power, allowing additional flexibility for specialized medical or operational infrastructure, along with floor plan flexibility and tenant improvement opportunities. From a location standpoint, the property sits near St. Luke’s – Easton Hospital Campus within a dense residential catchment and an active mixed residential / retail corridor. Regional access is supported by direct connectivity to Route 22 and I-78. This location profile supports outpatient demand, staff access, and proximity to established healthcare drivers. The current positioning is best suited for outpatient medical, specialty clinic, counseling, and healthcare administrative users seeking a standalone medical office with an existing clinical buildout. Standalone clinical facility for lease with existing room layout and parking, well suited for SUD / MAT / IOP / OP / OBOT, behavioral health, outpatient medical, and counseling-related tenancy, with zoning support that streamlines approval pathways and supports ease of operational startup. Hospital-Medical District H-1 Permitted by right uses: C-11 Nursing home, C-12 Hospital, C-16 Assisted living facility, D-2 Medical Uses include; OTP / Methadone Clinic MAT / Addiction Medicine Ambulatory Surgery Center (ASC) Dialysis / ESRD Advanced Imaging (MRI / CT / PET) Infusion / Oncology Behavioral Health / IOP / PHP Pain Management Orthopedics / Spine GI / Endoscopy Ophthalmology / Retina / Cataract Plastic Surgery / Cosmetic Surgery Urgent Care General Specialty Medical

Property Type:

Office

Date on Market:

2026-03-26

Boothwyn Industrial for Lease - Delaware County

Date on Market:

2026-03-25

Warrington Office for Lease - Lower Bucks County

Date on Market:

2026-03-18

Glenolden Flex for Lease - Delaware County

Date on Market:

2026-04-21

Philadelphia Medical for Lease - Independence Hall

Prime ground-floor space at Independence Place, prominently positioned along the south side of Washington Square. Currently built out as a 2nd gen medical lab, the space is equally well-suited for a physician, dental practice, or boutique med spa seeking an upscale clientele. Co-tenants include a market, fitness center, salon, and dry cleaner, creating a built-in customer base. Ideally located in Society Hill, near Washington Square West, Old City, and Queen Village, the property benefits from strong residential density and steady commercial foot traffic in one of Philadelphia’s most established neighborhoods.

Property Type:

Multifamily

Date on Market:

2026-02-18

Philadelphia Office for Lease - University City

CIC Philadelphia provides a dynamic and collaborative hub for entrepreneurs, startups, and enterprises in the heart of Philadelphia's University City. Located at 3675 Market Street, the property offers workspaces and labs with best-in-class services and amenities on flexible terms. Whether a small or large organization, fully in-person or hybrid, CIC Philadelphia delivers turnkey and tailored solutions. An ecosystem of entrepreneurs, scientists, venture capitalists, and innovators of all backgrounds awaits at CIC Philadelphia, with major tenants such as Amicus Therapeutics and the University City Science Center. Private and shared move-in-ready lab facilities, customizable private offices with a capacity for up to 50 people, and coworking desks with library-style seating are available to meet business needs immediately. Every CIC Philadelphia member can access stellar amenities, including concierge-level guest services, dedicated operational and technical support, fully equipped and stocked kitchens, video conference rooms, phone booths, printers, copiers, and more. Plus, members enjoy a series of regularly scheduled events, from networking to education and wellness. Completed in 2018, 3675 Market Street features an impressive lobby, an on-site café, a LEED Gold certification, and access to the Quorum, an expansive 15,000-square-foot events and conference center. Situated in the heart of Philadelphia's innovation district, the building is close to PENN Presbyterian Medical Center, Drexel University, and the Keystone Innovation Zone (KIZ). This prime location is only a block from the Route 10 Tramway, served by the Market-Frankford Line subway, and near an activated streetscape and a future public square. The surrounding area features over 250 restaurants, 10 farmers markets, over 700 hotel rooms, and abundant retail and entertainment options. Cambridge Innovation Center (CIC) is transforming how innovation happens. Since its founding in 1999, CIC has grown to host over 2,000 companies in seven cities throughout the United States and Europe. For over twenty years, CIC has built dynamic communities that empower founders to create companies and develop groundbreaking solutions.

Date on Market:

2026-01-16

King Of Prussia Office, Industrial for Lease - King of Prussia/Wayne

The Discovery Labs is a five million square feet of R&D, lab, cGMP Manufacturing, data centers, and tech-enabled space. The greatest minds and most influential organizations unite here, at the birthplace of cell and gene therapy and mission-critical data centers. The Discovery Labs is located 20 minutes outside of Philadelphia, in King of Prussia, Pennsylvania. Our cluster has already attracted world-leading scientists, big tech, and leading science organizations. Built with unparalleled infrastructure to meet the immediate needs and continued growth of your business. The Discover Labs is an expansive hub of data, infrastructure, and life sciences in desirable Philadelphia market.

Date on Market:

2026-01-10