63 Life Science Properties for Lease in Pennsylvania, USA

Bethlehem Office/Medical for Lease - Lehigh Valley

Situated in the heart of the thriving LEHIGH Valley Industrial Park with It’s striking architecture and trade mark Rose Glass make this building one of the most recognizable in the entire industrial park. With great access to all major highways and thruways such as 22 ,78 ,33. Near Fedex UPS and the LehighValley Post Office this ideal location offers many amenities and a distinct style that makes this building a true stand out. The building is serviced by a large private parking lot and maintained to a high degree. Suite 200 is an upscale amenity rich office space situated in the heart of the thriving Lehigh Valley. FULLY FIT OUT LAB SPACE WITH MULTIPLE WORK AREAS AND SYSTEMS IN PLACE has access to executive style, restrooms, and common areas.

Property Type:

Flex

Date on Market:

2025-01-10

Erie Office, Office/Retail for Lease - Outlying Erie County

Knowledge Park is designed to be a research and development hub for forward-thinking, knowledge-driven businesses. It partners with companies seeking to innovate with the talent and resources of one of the country’s leading research universities. You’ll have infrastructure, property management, security and support services combined with talent and technology resources. It’s a unique environment for innovation.

Date on Market:

2023-06-28

Philadelphia Industrial for Lease - Northeast Philadelphia

9300 ASHTON ROAD PHILADELPHIA, PA FOR SALE OR LEASE ±27,906 SF FULLY AIR-CONDITIONED PROPERTY HIGHLIGHTS • Fully air-conditioned industrial condominium available for sale or lease • Ability to control up to approximately 167 parking spaces • Two (2) existing tailgate loading docks • Opportunity to create drive-in loading • New GAF TPO roofing system • New HVAC and air conditioning systems • Clear heights ranging from 19'8" to 20'8" clear under purlin • Suitable for manufacturing, warehouse, distribution, assembly, laboratory, research and development, and flex industrial uses • Exceptional parking ratio rarely found in comparable industrial properties • Significant recent capital improvements • Public utilities • Well positioned for owner-occupants, investors, and corporate users seeking a highly functional industrial facility LOCATION Strategically located in Northeast Philadelphia, the property offers exceptional access to the region's major transportation corridors. Roosevelt Boulevard (Route 1), Interstate 95, Woodhaven Road (Route 63), and the Bensalem Interchange (Exit 351) of the Pennsylvania Turnpike are all within minutes of the property. Center City Philadelphia is approximately twenty (20) minutes from the property, while New York City is approximately ninety (90) minutes away. The location provides excellent access to Philadelphia, Southern New Jersey, and the broader Northeast Corridor. The combination of immediate highway access, substantial parking capacity, full air conditioning, and flexible loading capabilities makes the property ideal for manufacturing, warehouse and distribution, assembly, e-commerce, laboratory, and service-oriented industrial users.

Date on Market:

2026-06-02

Warrington Office for Lease - Lower Bucks County

Date on Market:

2026-03-18

Glenolden Flex for Lease - Delaware County

Date on Market:

2026-04-21

Philadelphia Medical for Lease - Independence Hall

Prime ground-floor space at Independence Place, prominently positioned along the south side of Washington Square. Currently built out as a 2nd gen medical lab, the space is equally well-suited for a physician, dental practice, or boutique med spa seeking an upscale clientele. Co-tenants include a market, fitness center, salon, and dry cleaner, creating a built-in customer base. Ideally located in Society Hill, near Washington Square West, Old City, and Queen Village, the property benefits from strong residential density and steady commercial foot traffic in one of Philadelphia’s most established neighborhoods.

Property Type:

Multifamily

Date on Market:

2026-02-18

Philadelphia Office for Lease - University City

CIC Philadelphia provides a dynamic and collaborative hub for entrepreneurs, startups, and enterprises in the heart of Philadelphia's University City. Located at 3675 Market Street, the property offers workspaces and labs with best-in-class services and amenities on flexible terms. Whether a small or large organization, fully in-person or hybrid, CIC Philadelphia delivers turnkey and tailored solutions. An ecosystem of entrepreneurs, scientists, venture capitalists, and innovators of all backgrounds awaits at CIC Philadelphia, with major tenants such as Amicus Therapeutics and the University City Science Center. Private and shared move-in-ready lab facilities, customizable private offices with a capacity for up to 50 people, and coworking desks with library-style seating are available to meet business needs immediately. Every CIC Philadelphia member can access stellar amenities, including concierge-level guest services, dedicated operational and technical support, fully equipped and stocked kitchens, video conference rooms, phone booths, printers, copiers, and more. Plus, members enjoy a series of regularly scheduled events, from networking to education and wellness. Completed in 2018, 3675 Market Street features an impressive lobby, an on-site café, a LEED Gold certification, and access to the Quorum, an expansive 15,000-square-foot events and conference center. Situated in the heart of Philadelphia's innovation district, the building is close to PENN Presbyterian Medical Center, Drexel University, and the Keystone Innovation Zone (KIZ). This prime location is only a block from the Route 10 Tramway, served by the Market-Frankford Line subway, and near an activated streetscape and a future public square. The surrounding area features over 250 restaurants, 10 farmers markets, over 700 hotel rooms, and abundant retail and entertainment options. Cambridge Innovation Center (CIC) is transforming how innovation happens. Since its founding in 1999, CIC has grown to host over 2,000 companies in seven cities throughout the United States and Europe. For over twenty years, CIC has built dynamic communities that empower founders to create companies and develop groundbreaking solutions.

Date on Market:

2026-01-16

Philadelphia Office for Lease - University City

Property Type:

Specialty

Date on Market:

2025-10-23

Lower Gwynedd Flex for Lease - Ft Wash/Spring House

Date on Market:

2025-10-17

Philadelphia Office for Lease - University City

Date on Market:

2025-08-22

Bethlehem Industrial for Lease - Lehigh Valley

o Parking: 2.87/1,000 SF (96 spaces total) o DI Water: RODI System in place o Power: 2,500a/240v Heavy o Backup Generator: Diesel o 2 Air Compressors o 3 Cold Rooms o 1 Dock-High Loading Dock o 13’2” Clear Height

Date on Market:

2024-10-17

Lower Gwynedd Office for Lease - Ft Wash/Spring House

Property Type:

Flex

Date on Market:

2024-10-07

Pittsburgh Office, Office/Medical for Lease - Greater Downtown

This unique property consists of highly customizable office and research/lab spaces on two floors around a central 2.5 story Atrium. The building was completely renovated in 2002. Both interior and exterior evoke a Contemporary California Industrial aesthetic complete with exposed timber/steel, metal panels, aluminum window walls, exposed brick, hardwood floors, wood plank ceilings with exposed ductwork and abundant daylight throughout. Two balconies provide exterior access. Tenants are also granted access to an off-street parking area with 55 spaces located at the rear of the building. The building is within walking distance to the SouthSide Works and the East Carson Street Business District. Located not far from the Hot Metal Bridge, the totally renovated structure provides easy access to Second Avenue's office properties and Oakland's University/Hospital corridor. The present and future Tenant mix is being reconfigured to accommodate specific adjacencies of Lab/Research (wet lab), Robotics, and Office related space. Floor sizes are up to 12,400 SF for a total of 28,800 GSF. The building design affords Suite sizes of 1,800sf up to and include full floor use. The building's technical infrastructure consists of Lab-rated HVAC systems (HEPA filters) complete with lab humidity control/ pressurized support space, emergency back-up power, a separate feed for 480V power, a 120/208 feed, and lab exhaust and filtration for hoods; air, gas, and vacuum systems. Access is controlled via an Exterior/Interior security with card access entry. There is a passenger elevator and Restrooms on each floor. Rooftop Lab Air-Handlers; Rooftop AHU's for Office and Common Areas; Hot water boiler/steam reheat for Lab Humidity Control. Fully sprinklered; Security monitoring/Fire Alarm with 24/7 remote monitoring. • 24 Hour Access • Security System • Central Heating • Partitioned Offices • Bio-Tech/ Lab Space • Signage • High Ceilings • Secure Storage • Property Manager on Site • Skylights • Natural Light • Air Conditioning

Date on Market:

2025-04-09

Philadelphia Office/Medical for Lease - University City

Multifamily property with retail spaces on the lower levels. Unparalleled location just steps from UPenn and Drexel campuses and less than one mile from University of the Sciences. Walking distance to/from Penn Presbyterian, Hospital of the University of Pennsylvania(HUP), and Children’s Hospital of Philadelphia (CHOP).

Property Type:

Multifamily

Date on Market:

2023-11-09

Philadelphia Retail for Lease - University City

400,000 SF mixed-use office and lab building with ±20,000 SF ground floor retail space.

Property Type:

Office

Date on Market:

2023-03-21

Philadelphia Office, Retail for Lease - University City

Seated at the heart of Philadelphia’s life sciences community, 3201 Cuthbert is perfectly positioned and equipped to support discovery, collaboration, and innovation in the field, with the most robust life sciences infrastructure in the region.

Date on Market:

2023-03-21

Philadelphia Office for Lease - University City

3711 Market is a premier lab and office building designed to accomodate the needs of today's biotech and life science companies. 3711 Market is conveniently located at the heart of uCity Square, within walking distance of University City's world class Universities, Health Systems, and Research Institutes. 3711 Market is home to fast growing biotech companies, established pharmaceutical companies, and research groups developing the next generation of curative therapies. 3711 Market provides robust lab infrastructure in addition to a 500 Car Parking garage and retail amenities including Han Dynasty and Orange Theory Fitness.

Date on Market:

2023-08-10

Exton Office for Lease - Exton/Whitelands

Glenloch Corporate Center is a three-story Class A office building in the Exton/Whitelands submarket with 1,432 SF- 15,000 SF of available space for lease. Zoned OL for business, medical, and R&D uses, it features mature landscaping, three ponds, an outdoor patio, a loading dock, and a shared kitchen. The property offers direct access to Route 202, with additional connectivity via Route 30, Swedesford Road, and multiple SEPTA Paoli/Thorndale Line stops, providing convenient commutes and proximity to retail, dining, and nearby business hubs.

Date on Market:

2024-05-28

Philadelphia Office for Lease - Market Street West

Positioned at the epicenter of Philadelphia’s thriving bioscience corridor, 2300 Market Street delivers a next-generation research environment designed to accelerate discovery. This 225,000 SF life science hub combines state-of-the-art infrastructure with a premier Center City address, offering unmatched connectivity to University City’s academic institutions and the vibrant Market Street lifestyle. The building’s flexible lab-to-office ratio, soaring ceilings, and robust mechanical systems create an adaptable platform for cutting-edge R&D. Tenants will enjoy private terraces, a serviced café and lounge, fitness amenities, and secure bicycle storage—all complemented by onsite and adjacent parking. With LEED Gold and Fitwel certifications, 2300 Market sets a new benchmark for sustainability and wellness in life science real estate. Steps from Rittenhouse Square and 30th Street Station, this location provides seamless access to regional and national transit, while surrounding retail and dining options foster collaboration and convenience.

Date on Market:

2025-12-11

Bethlehem Office/Medical for Lease - Lehigh Valley

This two-story, Class A office building offers multiple suites including two prime first floor suite with excellent visibility and accessibility. Recently updated with modern lobby and common area renovations, the building provides a welcoming environment with ample parking for both staff and visitors. Located near residential areas and highways, with strong demographics, it’s home to a dynamic mix of medical and office professionals. Positioned directly off Route 512 with easy access to Routes 22, 33, and 378, the property is both convenient and connected. A generous tenant improvement bonus is available, making this an ideal opportunity for tenants looking to buildout their custom space.

Property Type:

Office

Date on Market:

2026-04-27

Wayne Flex for Lease - King of Prussia/Wayne

INQ 400 is a single story 138,065 SF building located in Wayne, PA within close proximity to major life science hubs. Zoned to meet the needs of all aspects of life sciences, the building was originally constructed in 1969 and is under redevelopment to specifically meet the needs of “speed to market”. After extensive review with expert architects, it was found that a majority of the building’s existing infrastructure lends itself perfectly to both cGMP and R+D. This includes DX HVAC roof top units, 34 KV primary electrical service, gas, water, sanitary and fire protection. There is also a 500 KW diesel emergency generator on the property. The 20’-24’ ceiling heights throughout the building provides companies with the flexibility to add additional mezzanine, making it ideal for manufacturing. Ample interior loading docks throughout the building are also in place for ease of inbound and outbound materials. Additional enhancements underway include a new façade, installation of a 6 inch water line and the addition of a rooftop chiller.

Date on Market:

2021-07-26

Ambler Office, Flex for Lease - Ft Wash/Spring House

Spring House Innovation Park, or 'SHIP', is Greater Philadelphia's premier research and development focused business park with over 600,000 SF of planned or existing laboratory and office space across 130+ acres with the capabilities of accommodating requirements ranging from a few hundred square feet of startup/incubation space to over 100,000 SF. There is additional land within SHIP which can accommodate small to large custom build-to-suit requirements as well. Aside from Class A R&D space, many amenities are planned at SHIP including a campus food service/conference center building, indoor/outdoor fitness, a walking trail throughout the campus, and outdoor seating and meeting areas. Tenants can take advantage of a knowledge community at SHIP which ranges from some of the newest companies up to the largest and most established institutions in the world.

Date on Market:

2026-05-05

Philadelphia Multiple Space Uses for Lease - University City

3440 Market Street is a six-story (6-story), 120,000-square-foot state-of-the- art wet and dry laboratory facility. This ?exible ?oorplate provides users with 10’ ?nished ceilings, the ability to plan their layout ef?ciently and an impressive window line for great natural light throughout. The building is designed to accommodate typical of?ce, clinical and lab uses. The 19,600 RSF ?oor plates, 14.8’ slab-to-slab - 10’ ?nished ceiling heights maximizes the amount of natural light throughout the structure. 3440 Market Street incorporates many energy saving features, state-of-the-art systems, sustainable design and construction practices, has ?ve levels of parking (500 spaces), and substantial city and state tax (KIZ/KOZ) bene?ts available. The building will incorporate many energy saving features, state-of-the-art systems, and sustainable design and construction practices. The building is designed to accommodate typical of?ce, clinical and lab uses.

Date on Market:

2025-10-23

Canonsburg Office, Flex for Lease - Washington County

The Stealth Technology Center at 333 Technology Drive is a newly renovated office building with ample on-site amenities that help office, tech-flex, R&D, and any other tenants needing lab space recruit and retain top talent. This four-story, ±116,000 square-foot office tower is under new ownership, new management, and new improvements completed in 2020 include new common area restrooms, signage, landscaping, and a new roof. Additionally, newly added, tenant-focused amenities include a lounge with a putting green, corn hole boards, foosball tables, ping pong tables, a balcony, and vending machines, and an outdoor patio with picnic tables and umbrellas. Tenants also enjoy an on-site café, 24/7 suite access, second-floor balconies in select suites, energy-efficient reflective glass that cuts heat rays by 50%, architectural glass window features, and options for Comcast, Verizon, DQE, and Fibernet connectivity. Stealth Technology Center is home to the Health Club at Southpointe, providing a full-service fitness facility complete with group classes, personal training, complimentary towels, locker rooms, childcare, and corporate rates. Free Health Club memberships are offered with new leases. Current availabilities include a range of Class A office suites with 10’ finished ceiling heights, loading dock and drive-in access, a warehouse with 16’ ceilings, and options for furniture. Employees enjoy abundant parking, at a ratio of 5 per 1,000 square feet, and easy access to I-79, which conveniently connects to the Pittsburgh International Airport and Downtown Pittsburgh.

Date on Market:

2026-06-18