34 Life Science Properties for Lease in Philadelphia, PA, USA

Philadelphia Coworking for Lease - Delaware County

International Plaza I is a 6-story, Class-A, office building consisting of 194,411 sf. Premier location adjacent to Philadelphia International Airport with complimentary shuttle service to airport and City Center train depot with link to Center City and SEPTA bus service.The building features include: fiber optic served; all new HVAC - elevators and mechanical systems; and completely refurnished restrooms. It also offers a corporate lunchroom seating 400 people, ample free parking, 24-hour manned interior & exterior security, spacious and modern corporate dining facility, beautifully landscaped grounds, and interior and exterior security.The building features include: 24/7 Building Access, Free Airport Parking and Shuttle for Tenants, Philadelphia Address, Banking, Convenience Store, Food Service, On Site Management, Property Manager on Site, Security System, Barber Shop/Hair Salon, Conference Rooms

Property Type:

Office

Date on Market:

2014-02-19

Philadelphia Office for Lease - University City

One uCity Square is a premier Class A lab and office tower rising 13 stories in the heart of Philadelphia’s University City, a nationally recognized innovation district. Delivered in Q3 2022, this ±400,000 SF trophy asset is part of the transformative 7.7 million SF uCity Square mixed-use development, which integrates life sciences, academic institutions, and entrepreneurial energy into a walkable, transit-rich ecosystem. Tenants will benefit from a dynamic work environment designed to attract top-tier talent. The building features 15-foot slab-to-slab heights, 32K SF floor plates, private outdoor terraces, and panoramic views of Center City and Fairmount Park. It is the only building in Philadelphia to offer 100% outside air, bipolar ionization in common areas, and MERV 14 filtration—delivering air quality nearly double that of typical commercial buildings. One uCity Square is located within both a Keystone Opportunity Zone and a Federal Opportunity Zone, and qualifies for a 10-year real estate tax abatement, offering substantial financial advantages. The site is adjacent to institutions such as Penn Medicine, Drexel University, and CHOP, and is served by multiple transit options including Amtrak, regional rail, subway, and trolleys. The surrounding uCity Square community includes ground-floor retail, activated plazas, and curated programming such as Venture Café events and outdoor wellness activities. Tenants also enjoy hospitality-inspired lobbies, structured parking, indoor bike storage, and contactless entry from street to suite.

Date on Market:

2025-09-29

Philadelphia Coworking for Lease - University City

Enviable connectivity with a riverside location, this landmark location in University City is ideal for businesses that want to make this city their own. The CIRA Center Office Space has a direct connection to Amtrak’s 30th Street Station, so it’s convenient for commuters and business travel. This striking building with a strong presence in Philadelphia’s skyline offers a rooftop park - the perfect place to relax and make plans between meetings. Step outside to explore downtown Philadelphia or take in the views of the Schuylkill River.

Property Type:

Office

Date on Market:

2023-06-15

Philadelphia Office for Lease - University City

Date on Market:

2007-07-17

Philadelphia Office for Lease - University City

Class A office building offering office, lab and R&D space.This building is in a Keystone Opportunity Zone (KOZ). The glass and steel 17 story tower will be a landmark structure on the southwest corner of 34th & Market Streets. From its' upper floors the building will offer impressive views in all directions. It will be the first impressive tower that many visitors to the Science center will see as they approach. The University of Pennsylvania, The Children's Hospital of Philadelphia, Drexel University, and The Wistar Institute are all in close proximity to the site.

Date on Market:

2007-07-19

Philadelphia Office for Lease - University City

3020 Market Street is a LEED - SILVER certified boutique office building and tax abatement property well-positioned in the University City District's thriving research and technology corridor. Situated one block from Philadelphia's 30th Street Station, the building's prime location provides its tenants with a wide range of conveniences and amenities, such as access to Penn Park, Indego (Philly Bike Share) stations, the Schuylkill River Boardwalk and the popular food truck lineup at The Porch at 30th Street Station.

Date on Market:

2025-02-12

Philadelphia Office for Lease - Navy Yard

4751 League Island Blvd presents a rare sublease opportunity within Philadelphia’s thriving Navy Yard innovation district. Purpose-built for biotech and advanced therapeutics, this facility offers up to 82,000 SF of flexible space, including ISO-7 and ISO-8 cleanrooms, support labs, cold storage, and warehousing. The building is engineered for speed-to-market and operational efficiency, with robust utility infrastructure including compressed air, CO2, N2, and backup power systems. Tenants benefit from seamless integration of office, R&D, and manufacturing areas, with options for dedicated entrances and future expansion. The site is part of a 400,000 SF manufacturing campus adjacent to CDMO and testing services, supporting the full lifecycle of life science operations. Located just minutes from Philadelphia International Airport, University City, and Center City, the Navy Yard offers unmatched accessibility and lifestyle amenities. With over 20 acres of parks, waterfront trails, and on-site dining, this vibrant ecosystem attracts top talent and fosters innovation. The sublease runs through 2037, providing long-term stability in a premier location.

Property Type:

Flex

Date on Market:

2025-10-23

Philadelphia Office for Lease - University City

Pennovation Center is an innovation hub with a variety of premium shared or private space options for innovators and researchers around the Tri-State area. Pennovation Center fosters a sense of community and encourages collaborative endeavors within the Pennovation Works, and regional innovation, ecosystem

Date on Market:

2024-02-20

Philadelphia Office for Lease - University City

Located within uCity Square—a dynamic 8 million SF master-planned district—tenants benefit from proximity to leading institutions such as Penn Medicine, Drexel University, and the Wistar Institute. The area is home to over 200 companies and 15,000+ knowledge workers, with direct access to multiple transit stations and just 8 miles from Philadelphia International Airport. The building also offers access to a 425-bench serviced lab facility, vivarium, and drop-in lounge, making it a premier destination for innovation and collaboration.

Date on Market:

2025-08-22

Philadelphia Coworking for Lease - University City

Property Type:

Flex

Date on Market:

2024-11-13