13 Life Science Properties for Lease in Pittsburgh, PA, USA

Pittsburgh Office, Flex for Lease - East End

The Edison at 201 N Braddock Avenue offers dynamic flex and office space, ideally located in the bustling Rockwell Park redevelopment in Pittsburgh's East End. This six-story, 200,000-square-foot building boasts efficient floor plates for flexible configurations, high ceiling heights, and large windows allowing abundant natural light and sweeping city views. A variety of office space, industrial flex, creative lofts, mixed-use, and research and development space exists, ranging from whole floor plates to small singular office users. The expansive layout encourages collaboration and innovation, making it an ideal environment for businesses looking to foster a dynamic and productive work culture. Current tenants already calling The Edison their home include a vibrant mix of art studios, photographers, designers, prototyping, robotics, tech and development tech companies from single users to Fortune 500 companies. Rockwell Park is a transformative, 24-acre mixed-use redevelopment campus consisting of office, advanced manufacturing, light industrial, retail, and multifamily space located in the heart of Pittsburgh. This owner-operated campus-style site hosts a robust collection of community-based amenities designed for during and after work including shared kitchens, locker rooms, showers, mailrooms and more. Functional amenities facilitating our tenant’s self-sufficiency include ground level loading docks with tall ceiling heights and large windows. Flexible space from tenant lounges to collaboration areas provides a change of scenery throughout the work day or accommodates group breakouts. Throughout the park are several outdoor terraces patios and seating areas, promenades accentuated by professional landscaping, event space, concierge, and ample on-site parking and bike storage. A wealth of walkable retail and restaurants are present, including East End Food Co-op, Fresh International Market, Commonplace Coffee, and more. The East End Food Co-op is part of Rockwell's campus, and Construction Junction is a valued neighbor. Once home to transformative business leaders like Heinz, Carnegie, Edison, Westinghouse, and Rockwell, this vibrant area is poised to inspire the next generation of innovators. Point Breeze neighborhood is made up of prominent residential communities, community-based businesses, museums, and the region's largest urban green space in Frick Park. Centrally located with easy accessibility and superior convenience, The Edison at Rockwell Park is positioned a five-minute drive to Interstate 376 and Route 28 and a 15-minute drive to Downtown Pittsburgh. Pittsburgh International Airport is a 30-minute drive away for convenient out-of-town travel. Access to a deep talent pool from the surrounding residential areas, leading innovative organizations, and higher education establishments, including the University of Pittsburgh, Carnegie Mellon University, and 3M, are some of the many reasons robotics, software, coding, data analytics, Large Language & Generative AI pioneers are attracted to this area. Pittsburgh is also home to Carnegie Mellon's Robotics Institute, the world's most extensive robotics R&D program, as well as the Advanced Robotics for Manufacturing Institute and the National Robotics Engineering Center, among others.

Date on Market:

2025-07-23

Pittsburgh Office, Office/Medical for Lease - South Pittsburgh/Rte 19

Upper St Clair's Summerfield Commons Office Park is home to many successful business, the strategic location and peaceful atmosphere make our park perfect for any business looking for accessibility while avoiding noise and congestion. Summerfield offers professionals a park like setting, walking trails, on-site maintenance, and waterscapes. The property consists of 11 Buildings, totaling 93,742 square feet and a variety of suite ranging from 681 square feet to 4,930 square feet. Conveniently located in the heart of Upper St. Clair, at the corner of Boyce Road and Rt. 19, is in close proximity to shopping, dining establishments, and major roadways such as I-79 and I-376. Only 10 miles from downtown and within 20 of Pittsburgh International Airport. Additional Features Include: -Individual Climate Controls -Private Entrances -Private Restrooms -Spaces can be Built-to-Suit -Office Views of Park & Waterscapes

Date on Market:

2026-01-02

Pittsburgh Office, Retail for Lease - Parkway West Corridor

Foster Plaza 8 – Pittsburgh Office Space 730 Holiday Drive | Pittsburgh, PA 15220 1,500 – 24,297 SF | Class A Office Space at Class C Pricing Foster Plaza 8 offers renovated Class A office space with flexible layouts and modern amenities at unbeatable rates. Located in Pittsburgh’s Green Tree business corridor, this building is ideal for a wide range of businesses. Property Highlights: - Class A space at Class C pricing with price-beat guarantee - Renovated interiors with LED lighting and updated lobby - Fitness center with showers - On-site café, hotel, daycare, and access to Greentree Sportsplex - Immediate access to I-376; minutes to Downtown and airport - Free surface parking - Part of a 1.1M SF, 12-building corporate campus Ideal Tenants: - Professional services (financial advisors, insurance agencies) - Legal practices and consulting firms - Tech startups and IT service providers - Healthcare specialists and boutique medical practices - Marketing, media, and design firms - Educational and training centers - Nonprofits and community organizations - Showrooms and customer service hubs - Retail concepts (restaurants, cafés, food service) - Wellness and beauty businesses (salons, barbershops, medspa) - Real estate offices and property management groups - Engineering and architectural firms - AI and tech companies (data centers, robotics, cloud computing, cybersecurity) - Corporate innovation labs and R&D offices - Startups and incubators Immediate occupancy | Flexible layouts | Price-beat guarantee Contact John Lam – Direct Leasing – President – Bluestone PMS 484-747-5776

Date on Market:

2026-04-23

Pittsburgh Office for Lease - Greater Downtown

Located in the heart of Pittsburgh’s Uptown innovation corridor, the Forbes Pride & Stevenson Buildings offer a rare opportunity to lease flexible, high-impact space in two architecturally distinctive, adjacent properties. The Forbes Stevenson Building features 14,661 square feet of prime ground-floor space in a landmark listed on the National Register of Historic Places—ideal for lab, medical, office, or nonprofit use. Just next door, the Forbes Pride Building delivers over 48,000 square feet of beautifully converted factory-loft office, medical, therapy and lab space with soaring ceilings, arched windows, and floor plates ranging from 1,350 to 13,200 square feet. Both buildings are directly across from UPMC Mercy and steps from Duquesne University’s new medical school, surrounded by major institutional and mixed-use developments. Tenants benefit from abundant natural light, modern infrastructure, on-site parking, in-person security, and professional management. With direct access to the new Bus Rapid Transit University Line and proximity to major highways, these properties offer unmatched connectivity. This is a unique chance to secure space that blends historic character, modern functionality, and strategic positioning in one of Pittsburgh’s most dynamic and rapidly evolving neighborhoods.

Date on Market:

2025-06-24

Pittsburgh Multiple Space Uses for Lease - Greater Downtown

2500 Jane Street offers versatile and conveniently located commercial spaces ideal for a variety of business uses. This two-story brick building features an elevator and is positioned in a well-traveled corridor. This property provides excellent visibility, accessibility, and proximity to major city routes.

Date on Market:

2026-03-11

Pittsburgh Office for Lease - Parkway West Corridor

Date on Market:

2025-09-25

Pittsburgh Office for Lease - East End

Date on Market:

2024-12-04

Pittsburgh Office for Lease - Parkway West Corridor

Property Type:

Flex

Date on Market:

2020-04-14

Pittsburgh Office for Lease - Parkway East Corridor

• Unique retail opportunity at the forefront of the RIC development and Hazelwood Green neighborhood • 1,400 – 2,000 sf of first-floor retail space • Perfect for café, luncheonette, or boutique eatery • Plenty of natural light • Adjacent to University of Pittsburgh’s Pitt BioForge and the Mill 19 research and development hub • Proximity to the Round House • Future developments include: Lytle Street Apartment Building, Pittsburgh Steelers multi-sport facility, and two acres of outdoor green space for events & community use

Date on Market:

2025-05-14

Pittsburgh Coworking for Lease - Greater Downtown

Inspire any team on Sidney Street Give your brand a boost with flexible office space on Sidney Street. Perfectly placed in the suburbs of South Side Flats, with stunning views across the Monongahela River, Sidney Street provides premium office space just a few minutes from downtown Pittsburgh. Take out an office in an area known for its vibrant nightlife and vintage shopping and expand your network in the heart of the city. You’ll find East Carson St + 24th St Bus Stop just a three-minute walk from the doorstep, and Station Square Subway Station is only 3 mile away. Make a great first impression with professional office space on Sidney Street. Impress potential clients and partners with stylish workspace in a smart, modern building. Help yourself to coffee from our well-equipped kitchen and work quickly with our business-grade WiFi. Get to know potential clients in a pro-business environment and collaborate with talented professionals in our dedicated coworking spaces. Customise your space to suit your unique needs and add logos, brand colors and more. Download the Regus mobile app and manage your space wherever you are in the world.

Property Type:

Office

Date on Market:

2024-07-12

Pittsburgh Office, Office/Medical for Lease - Greater Downtown

This unique property consists of highly customizable office and research/lab spaces on two floors around a central 2.5 story Atrium. The building was completely renovated in 2002. Both interior and exterior evoke a Contemporary California Industrial aesthetic complete with exposed timber/steel, metal panels, aluminum window walls, exposed brick, hardwood floors, wood plank ceilings with exposed ductwork and abundant daylight throughout. Two balconies provide exterior access. Tenants are also granted access to an off-street parking area with 55 spaces located at the rear of the building. The building is within walking distance to the SouthSide Works and the East Carson Street Business District. Located not far from the Hot Metal Bridge, the totally renovated structure provides easy access to Second Avenue's office properties and Oakland's University/Hospital corridor. The present and future Tenant mix is being reconfigured to accommodate specific adjacencies of Lab/Research (wet lab), Robotics, and Office related space. Floor sizes are up to 12,400 SF for a total of 28,800 GSF. The building design affords Suite sizes of 1,800sf up to and include full floor use. The building's technical infrastructure consists of Lab-rated HVAC systems (HEPA filters) complete with lab humidity control/ pressurized support space, emergency back-up power, a separate feed for 480V power, a 120/208 feed, and lab exhaust and filtration for hoods; air, gas, and vacuum systems. Access is controlled via an Exterior/Interior security with card access entry. There is a passenger elevator and Restrooms on each floor. Rooftop Lab Air-Handlers; Rooftop AHU's for Office and Common Areas; Hot water boiler/steam reheat for Lab Humidity Control. Fully sprinklered; Security monitoring/Fire Alarm with 24/7 remote monitoring. • 24 Hour Access • Security System • Central Heating • Partitioned Offices • Bio-Tech/ Lab Space • Signage • High Ceilings • Secure Storage • Property Manager on Site • Skylights • Natural Light • Air Conditioning

Date on Market:

2025-04-09

Pittsburgh Office for Lease - Oakland

The Riviera is the ideal location for your wet lab, biotech, and office space, situated in the heart of Pittsburgh’s Technology Center, just a quick 5-minute commute from Downtown. Overlooking the riverfront with views of Downtown and the Southside Marina, the property features an on-site fitness center, loaner bicycles, a DeFer Coffee and Tea shop, a conference center, outdoor patios and eating areas, and weekly BioBreakfast networking events for life sciences. The building benefits from abundant natural light and offers flexible first-generation space that you can customize to meet your needs. The Riviera also provides convenient accessibility with connections to I-376, bus lines, and dedicated university shuttles that link you to Oakland’s top talent. Additionally, the Pittsburgh Technology Center (PTC) includes multiple parking garages and connects to the Three Rivers Heritage Trail for biking and walking options.

Date on Market:

2025-12-18

Pittsburgh Office, Industrial for Lease - Greater Downtown

River Avenue Distribution and Technology District is a transformative project aiming to revitalize the historically significant former H.J. Heinz into a modern, functional warehouse. This multi-phase development offers two fully renovated modern Class A warehouse and flex buildings —Building 7 and Building 8 — along with research and development space positioned along the scenic Allegheny River. Buildings 7 and 8 represent the first chapter in a project that continues to build relevance to the Northern Pittsburgh area. Ideal users include last-mile distribution, flex/tech users, value- add manufacturing, biotech, autonomous development and research, and more. Phase I of the River Avenue Distribution and Technology District offers a total of 300,000 square feet of Class A warehouse with a minimum divisibility of 10,000 square feet and a maximum of 200,000 square feet and includes a contiguous internal 600-vehicle parking garage. Building 7 is a 141,615-square-foot property, subdividable to 50,000 square feet, featuring a 25-foot clear ceiling height, one drive-in door, 10 dock doors featuring overhead doors with dock shelters, dock lights, 60,000-pound mechanical levels, and additional dock potential. Building 8 is a 141,460-square-foot property featuring a 29-foot clear ceiling height and seven dock doors with dock shelters, dock lights and 60,000-pound mechanical levels. Both buildings have all-new LED lighting and ESFR 4-zone service. AFP- 1010 intelligent fire detection control system with combo audio visual, signal and strobe lights fire protection system. An on-site parking garage accommodates 600 vehicles and potential tractor-trailer staging. Phase 2 will feature state-of-the-art flex/research and development space with unparalleled views of the Allegheny River and the constantly evolving Strip District. River Avenue Distribution and Technology District is an in-fill location providing exceptional accessibility and proximity to major thoroughfares and area amenities. Ideally located along the Allegheny River, this project thrives in an advantageous location with quick and convenient access to Pittsburgh's Central Business District, public transportation, and rail service. Within a five-minute drive is unmatched access to the Strip District (Robotics Row), Lawrenceville, Downtown Pittsburgh, and primary transportation arteries such as Interstates 279 and 579, as well as Route 28. When high-end work environments, connectivity, and convenience are key, River Avenue Distribution and Technology District is the ideal destination.

Date on Market:

2025-06-26