23 Life Science Properties for Lease in Raleigh, NC, USA

Morrisville Office, Flex for Lease - RTP/RDU

Discover a Premier Commercial Opportunity in the Heart of the Raleigh-Durham Triangle! Welcome to 3300 Gateway Center Blvd, a state-of-the-art flex building designed to cater to a wide range of business needs. Whether you're a small office user, a life sciences innovator, or a logistics powerhouse, this property offers unparalleled flexibility, prime location advantages, and top-tier amenities to elevate your operations. With REGUS as a major anchor tenant, this building is the perfect environment to grow and thrive. --- Property Highlights: - Fully Sprinkled Flex Building: Offering the flexibility to configure office and/or flex space combinations to suit your business needs. - Prime Location: Centrally located in the Raleigh-Durham Triangle area, right next to RDU International Airport and off Interstate I-40. - Unique Setup: Flex spaces with access to common dock-high dock doors and wide corridors allow tenants to easily take deliveries directly to their spaces. This feature makes it ideal for warehouse, distribution, manufacturing, and light industrial tenants. - Anchor Tenant: REGUS, a leader in flexible workspace solutions, providing shared office spaces, conference rooms, and break areas. This allows flex tenants to focus on their core operations without worrying about additional office space requirements. --- Available Spaces: Space A: - Small individual offices or multiple office combinations. - Options for conference rooms or small lab spaces. - Highly configurable to meet diverse tenant requirements. Space B: - Versatile flex spaces suitable for a variety of uses including: - Lab space - Research - Distribution - Warehouse - And more. - Customizable to match tenant needs. Space C: - Two smaller flex/office spaces ideal for satellite offices or smaller entities. --- Amenities: - Common dock-high dock door with wide-rated corridors for seamless logistics. - Two large restroom facilities and showers available for all tenants, reducing overhead costs. - REGUS coworking space offering additional office spaces, conference rooms, and a break room. - Proximity to a wide variety of amenities in the surrounding area. --- Strategic Advantages: - Proximity to Tier-1 Universities: - Duke University - University of North Carolina at Chapel Hill - North Carolina State University - Access to a continuous supply of highly skilled workforce. - Zoning: - Zoned ORD (Office/Research and Development): - Supports a wide range of uses including office, institutional, research and development, light manufacturing, and more. - Designed to mitigate adverse impacts when located near residential areas. --- Ideal For: - Small offices - Distribution centers - Warehouses - Research and development (R&D) - Life science users --- Don’t miss this opportunity to secure your space in one of the most sought-after business locations in the Raleigh-Durham area!

Date on Market:

2025-07-20

Morrisville Office for Lease - RTP/RDU

Nestled in a vibrant Raleigh neighborhood, RDU Center I is an exceptional, multi-tenant office building with modern upgrades and convenient accessibility at 3000 RDU Center Drive. This two-story, 60,083-square-foot building comprises renovated lobbies, refreshed restrooms, and a new roof. The property features a two-story atrium entrance with a granite lobby and monumental staircase, along with a 10% core factor. Originally constructed in 1999, the property is situated in the RDU Center and is conveniently located at the intersection of Interstate 40 and Aviation Parkway. Situated on 7.99 acres in the heart of the Triangle, the property is set within a beautiful park-like setting with ample on-site parking at a 5.6/1,000 parking ratio. RDU Center I boasts unparalleled access to the Raleigh-Durham International Airport and Interstate 40, providing easy commutes and travel in and out of town. Strategically positioned at the core of the region’s dynamic life science and technology cluster, the property is in a prime Raleigh locale. Raleigh is notably the #1 IT city in the US after Silicon Valley. It is also home to three research universities, making for a highly educated workforce.

Date on Market:

2023-06-02

Raleigh Industrial for Lease - Northeast Wake County

Date on Market:

2026-02-03

Raleigh Office/Medical for Lease - Six Forks/Falls of Neuse

Property Type:

Office

Date on Market:

2026-01-20

Raleigh Flex for Lease - Route 1

Date on Market:

2026-01-05

Raleigh Flex for Lease - West Raleigh

Date on Market:

2024-10-15

Raleigh Flex for Lease - Glenwood/Creedmoor

Brier Creek Location. Multitenant building. The building offers lots of natural light in the office areas and has easy access to RTP, Durham, Chapel Hill, and Raleigh It's located minutes from I-540, Hwy 70, and RDU International Airport, and is near Brier Creek Shopping Center with restaurants, Target, Walmart,

Date on Market:

2026-03-03

Cary Office/Medical for Lease

Medical office space for lease in prominent building with strong visibility in Waverly Place.

Property Type:

Office

Date on Market:

2025-03-10

Raleigh Office/Medical for Lease - Route 1

This property offers an exceptional opportunity for businesses seeking a well-located, professionally maintained space in a dynamic and accessible area. Positioned within a thriving commercial corridor, the site benefits from strong visibility, convenient access to major transportation routes, and proximity to a wide range of retail, dining, and service amenities that support both daily operations and client convenience. Designed to accommodate a variety of professional, medical, retail, or service-oriented users, the property delivers a functional layout that allows businesses to operate efficiently while maintaining a welcoming experience for employees and visitors alike. Surrounding development reflects a healthy mix of commercial activity and established neighborhoods, contributing to steady traffic patterns and a stable customer base. Tenants can take advantage of the area’s robust infrastructure, including nearby highways and public transit options, making commuting simple and expanding the potential service radius. The broader community offers a strong economic environment, supported by a diverse workforce and consistent demand driven by surrounding residential density and business growth.

Property Type:

Office

Date on Market:

2025-09-25

Research Triangle Park Office/Medical for Lease - Research Triangle

Located at the intersection of Triangle Drive and NC-54 Highway in Research Triangle Park, North Carolina, this office and lab facility presents a premier opportunity to establish operations at the heart of one of the most innovation-driven corridors of the country. 2 Triangle Drive is a single-story, Class B building spanning approximately 31,000 square feet. Originally constructed in 1977 and extensively renovated in 2001 with a $4.1 million investment, the building features modernized biotech and lab infrastructure, 24-hour access, air conditioning, and prominent signage opportunities. It includes 135 surface parking spaces, making it ideal for tenants requiring both accessibility and specialized space. Adjacent to the property is Triangle 54, a master-planned, Class A office campus developed by The Keith Corporation and Jerico Development, designed to support innovative science and technology companies. This is just one of the numerous hubs in the Research Triangle that can help tenants develop vital professional partnerships. Central placement is another key locational advantage of 2 Triangle Drive, which aids in recruiting from the competitive workforces in Durham, Raleigh, and Chapel Hill. Employees will enjoy seamless commutes off Interstate 40 and proximity to great amenities such as Starbucks, Burn Boot Camp, Food Lion, Boxyard RTP, Brigs Restaurant, Chipotle, high-end multifamily communities, and much more.

Property Type:

Flex

Date on Market:

2025-08-29

Durham Office for Lease - Research Triangle

Newly constructed lab/R&D spec suites immediately available ranging from 6,880 RSF to 32,000 RSF. Back up power/generator, loading dock, and amenities throughout the campus.

Date on Market:

2025-07-15

Morrisville Coworking for Lease - RTP/RDU

Give Your Business a Boost in Morrisville Base your business in Morrisville, North Carolina, and enjoy flexible office space in an attractive location for offices, light industry, and hotels. Benefit from being located just north of Raleigh, North Carolina’s capital, in this suburb of the greater Raleigh MSA. Commute easily to your workspace using Interstate 40 which is on your doorstep. Welcome visiting clients at Raleigh-Durham International Airport which is under a 10-minute drive away. Whether you’re looking for a long-term home for your business or just a space to get your head down when you’re on the move, you’ll find what you need here. Spark innovation and find new opportunities to connect in this state-of-the-art office space. Bring your ideas to life in the designer workspaces and creative meeting rooms, fully equipped with superfast WiFi. Our friendly team is always on hand and happy to help should you need anything throughout the working day. Feel inspired by the hive of activity surrounding you and take a break after business meetings in our fully stocked kitchens. Relax after work by taking a stroll around one of the many beautiful lakes or parks that is near the office space. Entertain clients with some delicious food at a nearby restaurant.

Property Type:

Flex

Date on Market:

2024-09-20

Wake Forest Multiple Space Uses for Lease - Route 1

New 30-acre business community located along Star Road (US 1) near South Main Street (New Falls of Neuse Road) Conveniently located near a variety of business amenities, shopping, entertainment and restaurants, as well as a diverse residential area featuring both mature and new communities.

Date on Market:

2024-07-09

Research Triangle Park Flex for Lease - Research Triangle

Longfellow's Via Labs Purpose-Built Class A Lab Building is comprised of 266,480 rentable square feet and is located at the main-on-main RTP intersection of I-40 and Davis Drive with unparalleled visibility from I-40 with over 170,000 VPD. Via Labs at Hub RTP offers a highly walkable environment, offering many features within the campus including a high-end hotel, conference space, retail, 16-acres of green space, bicycle storage, and over 2,300 multifamily units, with full access to all HUB RTP has to offer including the existing Boxyard Retail.

Date on Market:

2023-03-17

Morrisville Flex for Lease - RTP/RDU

Date on Market:

2023-01-27

Raleigh Office/Medical for Lease - Six Forks/Falls of Neuse

8300 Health Park offers adaptable outpatient medical suites supported by space-planning services and a generous tenant improvement allowance. This is ideal for treatment rooms, surgical practices, dental work, lab testing, and a variety of healthcare-related users. The campus features an on-site café, a full-service pharmacy, and a state-of-the-art fitness facility with an indoor pool, basketball courts, and private showers. Outdoors, tenants enjoy a lakeside patio and 0.75 miles of walking trails that enhance the workplace experience. With more than four parking spaces per 1,000 SF, an attached covered garage, and easily accessible surface parking, the property ensures smooth daily access for both providers and patients. This site is surrounded by amenities to live, work, and play. Within a 5-mile radius, there are more than 30 eclectic restaurants, recreational amenities like gyms and country clubs, and name-brand stores like Whole Foods, Target, Dick’s Sporting Goods, and Home Depot. 8300 Health Park affords streamlined access to key arterial highways, including Interstate 540 and Route 50, and its central location places tenants within 16 minutes of three major hospitals and RDU International Airport. Offering convenience, flexibility, and a strong amenity package, 8300 Health Park stands out as a premier healthcare setting in the Raleigh market. Remedy Medical Properties is a leading owner and operator of outpatient medical real estate, delivering integrated services across investments, development, leasing, management, and strategy. We own and operate medical office properties so healthcare providers can focus on patient care. Remedy specializes in the leasing of medical office space and outpatient medical buildings for physicians, health systems, and medical groups nationwide. Our team works directly with providers to deliver flexible space solutions that support clinical operations, patient access, and long-term growth. Learn more at remedymed.com

Property Type:

Office

Date on Market:

2024-05-21

Durham Flex for Lease - Research Triangle

Date on Market:

2026-01-22

Raleigh Office for Lease - West Raleigh

1791 Varsity Drive is located in North Carolina State University’s world-class Centennial Campus, one of Raleigh-Durham’s premier office and research parks. Situated just south of NC State’s main campus and two miles west of Downtown Raleigh, the property benefits from an amenity-rich location just south of NC State’s main campus. Centennial Campus is a 1,314-acre research park owned and operated by NC State. The campus is home to more than 70 corporate, governmental and non-profit “partners,” along with 75 N.C. State research centers, institutes and departmental units and numerous colleges. In addition to the buildings and research centers, Centennial Campus also contains public walkways, a fishing pier and lake, game fields and an 18-hole golf course.

Date on Market:

2026-04-13

Morrisville Office, Flex for Lease - Research Triangle

Triangle LIFE is a major hub for science companies in North Carolina’s Research Triangle, connecting people, place and purpose in an amenity-rich atmosphere. Triangle LIFE centers around the life sciences and the people devoted to them. It’s a community of scientists in a shared ecosystem of energy and synergy where proximity is key. Everything works together to make working here remarkable. This is North Carolina’s legendary Research Triangle, the intellectual and creative intersection of three top universities. Raleigh Durham International Airport is just minutes away. Centrally located within this dynamic area, Triangle LIFE is a 100-acre oasis for life science companies on the pulse of what’s happening now and with the ability to anticipate what’s next.

Date on Market:

2026-01-21

Morrisville Flex for Lease - RTP/RDU

This Class A life science campus will offer four 160,000 SF mid-rise buildings and combine state-of-the-art lab space with unmatched amenities provided by Elevate, Longfellow’s proprietary tenant experience and hospitality program. Strategically situated in Research Triangle Park with proximity to surrounding lab and office campuses and offers easy access to major thoroughfares, nearby restaurant and retail amenities, and RDU International Airport.

Date on Market:

2021-03-11

Durham Flex for Lease - Research Triangle

Longfellow’s proprietary tenant experience and hospitality program, Elevate, curates events, programming and services exclusively for our tenant partners.

Date on Market:

2021-07-15

Durham Flex for Lease - Research Triangle

Date on Market:

2026-03-18

Research Triangle Park Flex for Lease - Research Triangle

WORLD-CLASS AGTECH CAMPUS The Alexandria Center®? for AgTech is the country's first and only multi-tenant and amenity-rich greenhouse campus. Positioned in the heart of Research Triangle Park (RTP)—one of the most prominent research and technology hubs in the United States—5 Laboratory Drive and 9 Laboratory Drive offers a prime leasing opportunity for tenants seeking proximity to innovation, talent, and connectivity. Surrounded by leading biotech, pharmaceutical, and tech firms, this address places your business at the center of a dynamic ecosystem that includes over 300 companies and tens of thousands of professionals. The property benefits from immediate access to major thoroughfares, including I-40 and NC-147, providing seamless connectivity to Raleigh, Durham, and Chapel Hill. Raleigh-Durham International Airport is just minutes away, offering convenient national and international travel options. The surrounding area features a mix of corporate campuses, research institutions, and green spaces, creating a balanced environment for productivity and wellness. Ideal for life sciences, R&D, or professional office users, the building is situated in a master-planned park known for its infrastructure, fiber connectivity, and business-friendly environment. Tenants may benefit from state and local incentives, including workforce development programs and tax credits, depending on use and employment impact. Whether you're expanding operations or relocating to a strategic location, 9 Laboratory Drive delivers the visibility, access, and prestige that forward-thinking companies demand.

Date on Market:

2026-01-30