33 Life Science Properties for Lease in San Jose, CA, USA

San Jose Office for Lease - North San Jose

Freestanding single-story office building located on Charcot Ave in San Jose between First Streer and Zanker Rd. The property had a major facelift in 2020 pushing it to be one of the nicest office space/flex buildings available. The property is highly visible with great street front presence, with signage and plenty of parking. The building was designed with maximum flexibility allowing for single or multi-tenant use. The General Commercial zoning allows office and educational uses with CUP. Six spaces are available for lease right away. Including one with a 2500 square foot Clean-Room with a rating of 10K. Please email sam.jalili@compass.com for NNN costs, and any other questions you might have.

Property Type:

Flex

Date on Market:

2020-07-03

Los Gatos Flex for Lease - Los Gatos/Saratoga

Date on Market:

2025-11-12

San Jose Flex for Lease - South San Jose

5799 Fontanoso Way is a ±93,650 SF Class A Office/R&D building located in San Jose. Constructed in 2000, the two-story building features a dramatic atrium lobby, expansive floor-to-ceiling windowline, robust lab infrastructure equipped with 4,000 Amps and elegant executive conferencing facilities. Employee health and wellness is benefited by a fitness area with showers, a cafeteria leading out to a sunny outdoor patio with seating, and direct access to the Coyote Creek recreational trail via a private gate. The project also enjoys immediate access to Highway 101, and offers companies a reverse commute for Silicon Valley employees.

Date on Market:

2019-02-26

Santa Clara Flex for Lease - North Santa Clara

Located in the Heart of Downtown Santa Clara.

Date on Market:

2025-05-23

San Jose Office for Lease - South San Jose

6140 Hellyer Avenue is a freestanding, single-story commercial property with 4,478 square feet of interior space. Built in 2006, it features 100% office buildout and a modern exterior with strong curb appeal. The building is situated in Hellyer Commons Industrial Park and is zoned Industrial Park (IP), offering a wide range of permitted and conditionally permitted business uses. The design emphasizes professional functionality with a balance of privacy and openness. Inside, you'll find multiple private offices, a large shared kitchen, open team workspaces, and common areas ideal for meetings or collaborative sessions. Optional furniture and tenant improvement packages allow new occupants to customize their environment with minimal hassle. This property stands out for its strategic location and ease of access. It's located just minutes from Highways 101 and 85, providing efficient connectivity throughout the Bay Area. The surrounding area is quiet, green, and offers a peaceful work atmosphere while maintaining proximity to South San Jose’s business districts, restaurants, and retail services. Key building features include: Fully built-out interior with drop ceilings, central HVAC, and private kitchen ADA-compliant design and restroom access Sprinkler system and emergency lighting Secure, single-entry layout for improved access control 36 dedicated surface parking spaces High-speed internet included Bike-friendly amenities and adjacent walking trails Energy-efficient construction with ample window coverage The IP zoning permits a wide range of businesses, including office users, clean-tech and R&D firms, biotech and pharmaceutical companies, and certain medical or therapeutic practices. Businesses seeking to operate as a medical office may apply for a Special Use Permit with the City of San Jose. Approval typically depends on the type of practice (e.g., non-surgical vs. surgical, patient traffic levels, equipment used). The building's layout and infrastructure support this kind of conversion. Whether you're seeking executive offices, research space, or clinical functionality, 6140 Hellyer offers a balanced environment with flexibility, location advantages, and move-in readiness. Reach out today to schedule a tour or request zoning compatibility guidance. Text, call, or email today: Piyush Kothary (408) 656-7643 Kothary@yahoo.com

Date on Market:

2025-07-21

Santa Clara Office, Flex for Lease - North Santa Clara

- Full-building available - Full Kitchen Ground Floor - First Floor 11’ Ceiling Height (Not Clear Height) - Second Floor 10’ to Ceiling Tile 3.000 Amps - Ground Floor Outdoor Patio - Elevator Cold Room in Warehouse - 4 Standard and 1 Accessible Bathroom - LED: 2/29/26 - 7 Cutouts for Roll Up Doors - 5 Showers on First Floor

Date on Market:

2024-11-21

Fremont Flex for Lease

Date on Market:

2024-07-12

Morgan Hill Flex for Lease

Date on Market:

2023-10-18

Los Gatos Office for Lease - Los Gatos/Saratoga

7,009 square feet

Property Type:

Flex

Date on Market:

2024-05-28