8 Life Science Properties for Lease in St. Louis County, USA

Hazelwood Office for Lease - Airport

Located in the highly active and business-friendly area of Hazelwood, Missouri, and adjacent to the St. Louis International Airport, the professional office property at 945-951 Hornet Drive offers an exceptional environment for companies seeking visibility, convenience, and a strong sense of community. Situated directly across from the Boeing campus, tenants will enjoy being part of a thriving corporate neighborhood. The property provides ample on-site parking, a high standard of professionalism, and a strong sense of safety, making it ideal for businesses that prioritize both functionality and prestige. The available move-in-ready spaces include flexible space options ranging from 1,200 to 3,500 square feet, ideal for growing teams as well as institutional tenants. Just minutes from St. Louis Lambert International Airport, the location offers seamless access to major transportation routes, with Interstate 270 directly adjacent, and both Interstates 70 and 170 only minutes away. This well-connected location sits just 3.9 miles from SSM Health DePaul Hospital, offering added strength for medical tenants. The area is also an established commercial hub, providing employees with easy access to exceptional conveniences, including retail, restaurants, and service-based amenities. 945-951 Hornet Drive poses an excellent opportunity for companies looking to establish or expand their presence in one of the most accessible and well-regarded business corridors in the St. Louis metro area.

Date on Market:

2026-04-08

Saint Louis Flex for Lease - I-270/Maryland Heights

Date on Market:

2026-03-24

Bridgeton Office for Lease - Airport

Date on Market:

2025-04-15

Creve Coeur Office/Medical for Lease - I-270/Olive Blvd

Office and Medical Office space available with views overlooking Creve Coeur Golf Course. Building includes abundant parking and is ideally located near I-270 and Olive Blvd.

Property Type:

Office

Date on Market:

2026-06-08

Saint Louis Office/Medical for Lease - Chesterfield/Hwy-40

Join the ranks of leading healthcare specialists and take advantage of superior visibility and connectivity with one of the high-end suites offered at 12855 N Forty Drive, the Walker Medical Building. 12855 N Forty Drive spans approximately 150,000 square feet across four stories and features a two-story parking garage, 24-hour access, ADA accessibility, and a backup generator for seamless operations and access. New tenants will be in good company with co-occupants in pediatrics, gastroenterology, neurosurgery, cardiology, family medicine, podiatry, general surgery, psychiatry, and more, a diverse mix to broaden referral networks. Walker Medical Building benefits from proximity to three major hospitals, Mercy (formerly St. John’s), Missouri Baptist, and St. Luke's, all of which are less than 10 minutes from the property. Local residents report a high payor mix and prioritize health and wellness with some of the most prestigious communities nearby, such as Town and Country, Chesterfield, Clarkson Valley, Ladue, and Des Peres. Connections to these patient pools are streamlined via direct access to Interstate 64 and other close arterial roadways. Many residents are organically drawn here, making this a convenient destination, with several local schools, colleges, country clubs, parks, and shopping districts moments away.

Property Type:

Office

Date on Market:

2026-05-12

Saint Louis Office for Lease - Creve Coeur/Hwy-67

Located in the heart of St. Louis’ 39 North District, 1001 N. Warson Road presents a premier opportunity for ag-tech, pharmaceutical, and life sciences users. This Class A facility features flexible office and laboratory space designed to support advanced research, innovation, and growth. Surrounded by industry leaders such as Bayer and Pfizer, the property offers tenants direct access to top-tier talent, cutting-edge resources, and a robust life sciences ecosystem within one of the region’s most established innovation corridors.

Date on Market:

2026-01-16

Saint Louis Office for Lease - Creve Coeur/Hwy-67

BRDG PARK is a post-incubation, wet laboratory and office building in the heart of 39 North. It is one of three buildings in the ag tech research park. BRDG PARK is also known as the Bio-Research & Development Growth Park at the Danforth Center to support the needs of life science companies. In 2010, this building was awarded LEED certification at the Gold level by the U.S. Green Building Council. The Bio-Research & Development Growth (BRDG) Park is uniquely prepared and positioned to host plant and life-science and clean-tech companies. BRDG Park is designed for companies from early-stage to those that have advanced their science, demonstrated proof of concept, raised additional funds and are poised for growth. There are several leasing opportunities at BRDG Park Building. Wexford can customize wet labs, dry labs and office space to meet your specialized life science, plant science, ag tech or clean tech needs. BRDG Park provides generous tenant improvement allowances which can help many companies by eliminating upfront costs and preserving capital for core business activities. Located on Warson Road just north of Olive Blvd. in St. Louis County's Creve Coeur market between Interstate 270 and Interstate 170.

Date on Market:

2026-04-29

Maryland Heights Flex for Lease - I-270/Maryland Heights

Worthington Access Drive is a masonry and concrete block building constructed in 1974, located in the Maryland Heights submarket. The property lies within proximity to Westport Plaza and major highway networks including Interstate 270 and Highway 364. It is situated in an “M-1” Light Manufacturing District with supporting amenities such as dining, entertainment, and retail nearby.

Date on Market:

2026-04-22