142 Storefront Properties for Lease in San Diego, CA, USA

Solana Beach Retail for Lease - North Beach Cities

330 Cedros at 330 S Cedros Avenue offers an exceptional opportunity to lease premium retail and office space within an award-winning mixed-use development in Solana Beach's renowned Cedros Avenue Design District. A true live-work-play destination, 330 Cedros delivers a mix of retail, dining, office, and residences in a vibrant, coastal setting animated by striking murals and a sleek neo-industrial design. Retail spaces feature attractive storefront windows and flexible floor plans, including Suite 100, an available end cap unit spanning 959 square feet with a striking double-height display window. For office users, second-floor suites offer open layouts or fully built-out options with private offices, conference rooms, and kitchen amenities. Each office also includes a balcony overlooking the lively Cedros Avenue promenade, creating a unique work setting. Sustainable design is central to 330 Cedros, with photovoltaic panels producing on-site electricity and electric vehicle (EV) charging stations for tenants and guests. The 78 shared rear parking stalls ensure swift access, while attached residences provide a built-in customer base, ensuring consistent traffic around the property. Dining is also steps away, with the coveted Rare Society next door, which delivers a celebrated culinary experience. Location and access further distinguish 330 Cedros. Two blocks from the beach and less than a mile from the Del Mar Racetrack and Fairgrounds, tenants are immersed in the coastal lifestyle that defines Solana Beach. The Solana Beach Coaster station is a short 10-minute walk, offering direct rail service throughout the region, while Camino Del Mar and Interstate 5 provide smooth roadway connections. Downtown San Diego lies 23 miles south, and San Diego International Airport is within a 28-minute drive, placing tenants at the intersection of community, convenience, and coastal charm.

Property Type:

Multifamily

Date on Market:

2026-01-05

San Diego Office/Medical for Lease - Uptown West/Park West

Hillcrest Healing Arts Center offers a serene medical office environment at 3636 5th Avenue in San Diego, California, thoughtfully designed to support wellness-focused users. The property fosters a calming, healing atmosphere and presents an opportunity to join a curated tenant mix of specialized medical and wellness providers, including specialty medical practices, acupuncture, massage therapists, and individual and family therapy practices. The multi-tenant property spans 9,840 square feet across three stories and features newly improved suites. Ownership offers attractive lease structures, including flexible short-term options and an all-inclusive rental rate covering electricity, utilities, operating expenses, and HVAC. On-site parking for both clients and tenants is available, further enhancing convenience within this well-positioned medical office setting. Located in the heart of Hillcrest along 5th Avenue, the Hillcrest Healing Arts Center is positioned within one of San Diego’s most vibrant and culturally diverse neighborhoods. The area offers convenient access to State Route 163 and Interstates 8 and 5 and is surrounded by a wide array of dining, retail, and service amenities. Hillcrest is widely recognized for its strong sense of community, anchored by the iconic Hillcrest Pride Flag at Pride Plaza, a central gathering place for major events, the nationally recognized Pride parade, and the popular Sunday farmers market featuring more than 175 vendors. At the western end of the neighborhood, the historic Hillcrest sign marks a lively district of shops, restaurants, and nightlife, while ongoing mixed-use and residential developments continue to energize the area. Hillcrest Healing Arts Center also benefits from proximity to major medical institutions, offering strong synergy with nearby healthcare users, including University of California, San Diego (UCSD) Medical Center and Scripps Mercy Hospital San Diego, as well as a wide assortment of private medical and dental practices. Just south, Balboa Park further enhances the location with its museums, cultural institutions, gardens, and the world-famous San Diego Zoo, reinforcing the property’s appeal within a highly amenitized, centrally located setting.

Property Type:

Office

Date on Market:

2026-03-09

San Diego Retail for Lease - Uptown West/Park West

519 University Avenue now offers a 786-square-foot storefront with a flexible layout, presenting a unique opportunity in the heart of the Hillcrest neighborhood. Formerly operated as a nail salon, the new prospective tenant can continue the established nail salon services and enhance the brand through rebranding, expanded services, and community outreach. Alternatively, the owner may choose to transform the space into a new retail venture. The possibilities are endless as this offering could accommodate any beauty or retail concept. Located in the heart of Hillcrest along University Avenue between 5th and 6th Streets, this prominent property benefits from exceptional visibility to both pedestrian and vehicular traffic. The corridor sees approximately 154,779 vehicles per day, underscoring its status as a heavily trafficked, well-established local thoroughfare. Surrounding 519 University Avenue is a dynamic mix of new and long-standing restaurants, dessert-focused concepts, vintage clothing boutiques, bookstores, coffeehouses, and other neighborhood-serving retail. The area is further bolstered by nearby major developments, including Normal Street Promenade, the UC San Diego Hillcrest Medical Campus, Plan Hillcrest initiatives, and Hillcrest Flats. Hillcrest is a vibrant neighborhood on San Diego's north side, best known as the hub of the city's LGBTQ+ community. The neighborhood within a 5-mile radius has a population of 536,983, with an average household income of $119,863. This population accounts for $7.3 billion in consumer spending.

Date on Market:

2025-09-29

San Diego Retail for Lease - Uptown East

Date on Market:

2026-04-30

La Jolla Retail for Lease

Now available in the highly desirable Bird Rock community of La Jolla, this charming 1,046 square foot retail space offers a rare opportunity in a premier coastal location just steps from the ocean along La Jolla Boulevard. The space features warm wood flooring throughout, creating an inviting and natural aesthetic ideal for boutique retail, gallery, wellness, or creative office use. Expansive bay windows provide excellent street presence and visibility while filling the space with abundant natural light. A skylight further enhances the interior, bringing in additional daylight and creating an even brighter, more open atmosphere. Vaulted ceilings add volume and character, complemented by ceiling fans that improve air circulation and comfort. Track lighting is installed throughout, offering flexible and modern illumination suitable for merchandising or display-focused layouts. A private kitchenette adds convenience for staff or daily operations. A non-ADA restroom is also included within the space. The property is serviced by street parking only, consistent with the surrounding walkable coastal village environment. Please note there is no HVAC system in place. Located in the heart of Bird Rock—one of La Jolla’s most sought-after seaside neighborhoods—this space benefits from steady local foot traffic, strong community demographics, and close proximity to the ocean, cafés, and boutique retail. An exceptional opportunity to continue or establish your business in a vibrant coastal enclave defined by charm, visibility, and classic La Jolla appeal.

Date on Market:

2026-04-30

National City Retail for Lease

Date on Market:

2026-04-22

La Jolla Retail for Lease

Date on Market:

2026-04-21

La Jolla Retail for Lease

Prime Prospect Street frontage in the heart of La Jolla Village. Positioned directly across from Eddie V’s and next to the upcoming Myka Greek Yogurt, this stretch continues to attract some of the strongest foot traffic in the market. Surrounded by top-performing restaurants, boutiques, and national brands, the location benefits from constant activity driven by affluent locals and La Jolla’s year-round tourism. This is one of the most walked and visible blocks in the Village. Approximately 200 feet of frontage provides exceptional exposure and strong signage presence along Prospect Street. Ideal for retail, café, dessert, or experiential concepts looking to make a statement in a tightly held, high-demand coastal market.

Date on Market:

2026-04-21

San Diego Office/Retail for Lease - Downtown

Introductory Rate: $2.95 PSF + U/J Corner office/retail space in prime Little Italy location with street level entrance Space features private offices, conference room, kitchenette, restroom, and ability for flexible floor plan changes Building signage and 5 dedicated on-site parking spaces in the adjacent lot Walking distance (0.5mi) to trolley stop and close proximity to Waterfront Park Adjacent to 2100 Kettner block, neighboring Tenants include: future Sugarfish, Postino, Herb & Wood, Crack Shack, Juniper & Ivy, Nolita Hall, Ballast Point, Mona Lisa, Bird Rock Coffee Roasters, Underbelly, Body Fit Training, The NOW Massage, Manivela Coffee, Slice House and many more!

Property Type:

Retail

Date on Market:

2026-04-21

San Diego Retail for Lease - PB/Rose Canyon/Morena

Date on Market:

2026-04-17

La Jolla Retail for Lease

Located at the gateway to the Village of La Jolla, 1006–1010 Torrey Pines Road offers a rare coastal retail and office presence in one of San Diego’s most affluent and walkable markets. The building features a highly visible street-front location with strong daily traffic and prominent frontage along a primary corridor entering La Jolla. Large storefront windows provide excellent natural light and strong branding and signage opportunities, making the property well suited for retail, office, or service-oriented users. The surrounding area is anchored by Girard Avenue, La Jolla’s most coveted retail street, and is within minutes of beaches, restaurants, hotels, and cultural attractions. The property benefits from exceptional walkability and proximity to a dense residential and professional population, creating consistent pedestrian and vehicular exposure. This location offers a truly unique coastal environment with unmatched visibility and accessibility in the heart of La Jolla

Date on Market:

2026-04-15

San Diego Office/Retail for Lease - Downtown

Highly visible storefront opportunity with tremendous signage along India St & W Ash St Coveted corner space with various demise options Located in Little Italy, Downtown’s most desired neighborhood withthe best restaurants Co-tenancy with Choice Juicery, Vinarius Wine Bar, Starbucks, and Fisher’s Seafood Walking distance to eateries including Queenstown, Born & Raised, King & Queen Cantina, Extraordinaty Desserts, Bird Rock Coffee Roasters, Morning Glory, Little Italy Food Hall, and many more Within the immediate vicinity of I-5, Santa Fe Depot, Core Business District, Waterfront Park and thousands of apartments

Property Type:

Multifamily

Date on Market:

2026-04-09

San Diego Office, Retail for Lease - Old Twn/S Arena/Pt Loma

Date on Market:

2026-04-08

Chula Vista Retail for Lease

Date on Market:

2026-04-07

San Diego Retail for Lease - College Area

Commercial retail space

Date on Market:

2026-03-24

La Jolla Office for Lease

Property Type:

Retail

Date on Market:

2026-03-23

San Diego Retail for Lease - Uptown West/Park West

Date on Market:

2026-03-18

Solana Beach Office for Lease - North Beach Cities

Property Type:

Multifamily

Date on Market:

2026-03-11

San Diego Retail for Lease - College Area

-College Area Business District -Space In Shell Condition -Can Be Built-Out To Your Liking -Possible Bathroom & Shower -Possible Kitchen & Cooking Area -Negotiable Terms On Improvement Needs -Zoning: CC-3-4 -Retail -Office -Salon -Barber -Hair Dresser -Profesional Call Or Text Agent For Tour

Date on Market:

2026-03-11

San Diego Retail for Lease - College Area

Prime street-level retail / service space in the heart of the SDSU College Area. Formerly The Chrome Lady Tattoo, this high-visibility end unit features ±1,205?SF, shared on-site parking, and excellent street frontage. Just 1 mile from SDSU with heavy foot traffic, daily vehicle counts of 28,000+, and a vibrant surrounding trade area of students, residents, and nearby retail. Ideal for retail boutiques, personal care or wellness studios, quick-service cafés, or creative experience-driven concepts. Move-in ready and available immediately at $3,500/month (CAM included).

Date on Market:

2026-03-08

San Diego Office/Retail for Lease - Old Twn/S Arena/Pt Loma

Property Type:

Retail

Date on Market:

2026-02-24

Lemon Grove Retail for Lease - East County

1st floor office. It was used as SPA business. Current layout is 3 rooms + 1 bath + 1 office + 1 reception. Any kind of business ok in this area. Lease term is negotiable. Please contact to Magic 858-703-0012

Date on Market:

2026-01-30

Solana Beach Retail for Lease - North Beach Cities

Date on Market:

2026-01-23

San Diego Retail for Lease - Uptown East

Urban Elements sits at the corner of 30th Street and Adams Avenue. Co-tenants include: Polite Provisions, Fortunate Son, and Swan Bar. Area tenants include Cantina Mayahuel, Wormwood, Air-Conditioned Lounge, Little While Coffee, Fuzz Coffee/Records, Et Voila French Bistro, Tajima Ramen, An's Dry Cleaning (gourmet ice cream)and many more.

Date on Market:

2026-01-14