142 Storefront Properties for Lease in San Diego, CA, USA

La Mesa Industrial for Lease - East County

Located in the desirable city of La Mesa with a rapidly growing population along with large retailers moving into the area. Surrounded by new development, schools, downtown La Mesa, and easy freeway access! • The property is located in the city of La Mesa, California, known for its vibrant downtown area with a mix of shops, restaurants, and cultural attractions. • La Mesa is home to popular events such as the weekly farmer's market, Oktoberfest, and the annual Flag Day Parade, drawing in a large number of visitors. • Nearby attractions include Lake Murray, a reservoir popular for hiking, fishing, and picnicking, offering residents and visitors recreational opportunities. • The area boasts a strong sense of community and is known for its local businesses, creating a supportive environment for new ventures and fostering a sense of local pride. • La Mesa is conveniently located near major highways, providing easy access to neighboring areas like San Diego, making it a desirable location for businesses seeking visibility and accessibility.

Property Type:

Retail

Date on Market:

2026-01-08

San Diego Office, Retail for Lease - Uptown West/Park West

Ground floor retail and second-floor office space available in the heart of Hillcrest’s vibrant urban core Turnkey fitness space featuring quality gym flooring, showers, and restrooms Modern second-floor office space with a kitchen, private offices, large open workspace, and smooth concrete floors 8 parking spaces available for office space Exceptional signage and visibility with 65 feet of frontage along University Avenue (22,926 ADT) Surrounded by top neighborhood amenities, including Negociant Winery, Hillcrest Corner Kitchen, Prager Brothers, Gossip Grill, and many more

Date on Market:

2026-04-28

San Diego Office/Retail for Lease - College Area

Property Type:

Retail

Date on Market:

2025-12-09

San Diego Retail for Lease - Downtown

Rare single tenant property in Gaslamp located on 5th Avenue, Gaslamp’s most sought after block and just south of Market Street Space can accommodate restaurant use, with single story for kitchen venting Opportunity for outdoor sidewalk patio seating Unique location to capitalize on Gaslamp Quarter, Petco Park, and Convention Center traffic Located in one of the most sought after entertainment and retail corridors in Southern California Surrounded by multiple luxury hotels including The Pendry, Hilton Gaslamp, Hard Rock, and OMNI Immediate proximity to Convention Center, Seaport Village, Campus at Horton, and East Village

Date on Market:

2024-08-19

San Diego Office, Retail for Lease - Old Twn/S Arena/Pt Loma

Midway Garden Plaza offers a well-positioned retail and office opportunity in the heart of San Diego’s Midway District, a vibrant commercial corridor near downtown and the harbor area. The center provides storefront visibility along a high-traffic area with convenient access to major thoroughfares, including Interstate 8, Interstate 5, and Pacific Highway. Businesses benefit from strong daily traffic counts and proximity to dense residential neighborhoods, major retail anchors, and entertainment destinations. The property includes multiple configuration options, featuring first-floor retail and second-floor office space adaptable for specialty retail, service-oriented businesses, or professional users. On-site surface parking (75 spaces) and prominent pylon signage maximize customer convenience and brand visibility. Midway Garden Plaza situates tenants in a transit-accessible location with nearby Coaster and Trolley stations, as well as San Diego International Airport just 2 miles away, providing exceptional connectivity.

Date on Market:

2025-12-04

La Jolla Office for Lease

Property Type:

Retail

Date on Market:

2025-11-25

Solana Beach Retail for Lease - North Beach Cities

Creative Office or Retail Space Available 710 SF 2009 Construction Sublease (Through Dec. 31st, 2026) or Direct Deal Available Built out as Creative Office (Open Space and One Private Office) High Ceilings Polished Concrete and Teak Wood Flooring Two Reserved Parking Spaces Signage to Hwy 101 All furniture available Call for Rates Jason Smithson 858 361-1195

Date on Market:

2025-11-13

San Diego Retail for Lease - College Area

Date on Market:

2025-11-12

San Diego Retail for Lease - College Area

Currently Built out for Charter School. Beautiful brand new construction as of 2017. Open Plan with perimeter offices/conference rooms/break rooms/bathrooms Sublease through 8/31/2029 or direct deal available New Roof/HVAC/Electrical CUP in Place Dedicated 92 Stall underground parking

Date on Market:

2025-11-11

San Diego Office/Retail for Lease - PB/Rose Canyon/Morena

Commercial building with ground floor retail and seven offices on 2nd floor. This building has great visibility off of Linda Vista Rd and includes 18 parking spaces. Great location for small business including Insurance, Immigration, Tax, Accounting, and other small busineses All units have laminate flooring, bathrooms, AC Split Units, and 18 parking spaces This property is located near kearny Mesa employment hub with commercial, industrial and government offices and has convenient access to I-163, I-805, and I-8.

Property Type:

Retail

Date on Market:

2025-04-18

San Diego Retail for Lease - College Area

- Located on the corner of El Cajon Blvd / Winona Ave

Date on Market:

2025-04-18

San Diego Office/Retail for Lease - Old Twn/S Arena/Pt Loma

Seize a rare leasing opportunity in the heart of Old Town San Diego — approximately 800 SF of versatile interior space complemented by an expansive 1,100 SF private patio, ideal for a restaurant, café, or boutique retail concept. The space arrives with significant infrastructure already in place, including brand-new plumbing, framing, a grease trap, and a $20,000 custom kitchen hood, giving your build-out a head start and serious cost savings. Whether you're envisioning an al fresco dining concept or a curated retail experience, the flexible layout and outdoor patio provide the perfect canvas to bring your vision to life. Positioned among Old Town's popular shops, restaurants, and high foot traffic corridors, this character-rich location delivers exceptional visibility, walkability, and the historic charm that draws locals and tourists alike. A turnkey foundation for a standout business presence — opportunities like this don't last long.

Property Type:

Retail

Date on Market:

2025-10-29

La Jolla Retail for Lease

THIS CLASSIC MID CENTRY BUILDING IS LOCATED IN THE HEART OF THE BIRD ROCK COASTAL COMMUNITY OF LA JOLLA ALONG BUSY LA JOLLA BLVD..

Date on Market:

2025-10-14

San Diego Office, Retail for Lease - Downtown

Date on Market:

2025-10-14

San Diego Retail for Lease - Park East

Available for lease for the first time in over a decade, 4223 30th Street presents a rare opportunity to occupy one of North Park’s most recognizable commercial buildings. The property offers ±5,900 SF of interior space plus an additional ±1,600 SF fenced outdoor patio, ideal for dining, entertainment, or gathering space. The entire building is available for lease, with the option to lease individual suites ranging from ±1,600 SF to ±5,900 SF. Positioned at the highly visible intersection of 30th Street and El Cajon Boulevard, this landmark property features the renowned “Greetings from San Diego” mural, making it a well-known destination within one of San Diego’s most vibrant and walkable neighborhoods. The building is thoughtfully designed for hospitality and creative concepts, featuring glass-panel roll-up doors, exposed wood ceilings, two built-out bar areas, four restrooms, and impressive 20-foot warehouse ceilings. Additional infrastructure includes 600-amp, 3-phase power and gas service, making it ideal for restaurant, brewery, distillery, café, retail, or experiential concepts. Previously home to a brewery tasting room and coffee roastery, the property benefits from a proven hospitality layout and strong local recognition. Surrounded by thousands of residents, new mixed-use developments, and established retail and dining destinations, the location offers exceptional visibility, accessibility, and foot traffic. With its iconic identity, flexible layout, and prime North Park location, 4223 30th Street provides a unique opportunity for a flagship concept looking to establish or expand in one of San Diego’s most sought-after commercial districts. Take a Virtual Tour by clicking this link: https://my.matterport.com/show/?m=nit1nfUN6pj

Date on Market:

2025-12-18

La Jolla Office, Retail for Lease

Pacific Coast Commercial is pleased to exclusively present 1055 Torrey Pines Road, a rare 2nd-generation restaurant opportunity in “The Jewel by the Sea.” This two-story, 8,345 SF multi-tenant retail/office building offers abundant parking with ±39 surface spaces (4.67:1,000 SF ratio) and prime visibility along Torrey Pines Road, traveled by 36,512 vehicles daily. Just minutes from La Jolla Cove, Shores Beach, UCSD, Pacific Beach, and the San Diego Airport, the property sits at the nexus of affluent demographics—183,000 residents within 5 miles, average household income of $132,557, and $2.9 billion in consumer spending. Co-tenants include Bridget’s Blooms, Cup of Bloom Coffee, Four By Four Construction, and legal services, creating a dynamic mix that draws both locals and tourists.

Date on Market:

2026-04-07

El Cajon Retail for Lease - East County

FOR LEASE – COMMERCIAL UNITS Prime Location | Flexible Options Unit A + Unit B (combined): ~2,200 sqft Unit C: Currently leased to a beauty salon at $3,500/month Important: Unit B (middle unit) cannot be leased by itself since it shares a single electric meter tied to Unit A. Lease Rate: $2.00/sqft + NNN Highlights: Great visibility in a busy commercial strip Flexible space – perfect for retail, office, or service business Modern layout with strong foot and car traffic

Date on Market:

2025-10-20

La Jolla Retail for Lease

1152 Prospect Street offers a rare retail space in the heart of Prospect Street. This property offers tremendous visibility from its unique architecture and frontage as well as benefitting from being next to some of the most visited restaurants and hotels in La Jolla. This property is located directly next to the historic La Valencia Hotel, Cormorant Boutique Hotel and upscale retailers and restaurants such as: Jaeger LeCoultre, Omega, CJ Charles Jewelers, Paneri, IWC Schaffhausen, Ian Ely Gallery, Westime, Gorjana, Dukes, The Whaling Bar, Eddie V’s, Georges at the Cove and many more. La Jolla Village is a destination for high end shopping, dining and tourism creating a strong potential clientele. Prospect Street is San Diego’s premier High Street for shopping and dining.

Date on Market:

2025-07-02

La Jolla Retail for Lease

Mixed Use complex consisting of retail plus residential.

Date on Market:

2025-06-17

La Jolla Office/Retail for Lease

Ideal for a beauty studio, barber shop or small jewelry boutique, this charming retail space sits near the front of the International Shops at 1237 Prospect—directly across from Lobster West and surrounded by high foot traffic. Located in the heart of La Jolla Village, steps from the ocean, this is a rare opportunity to establish your brand in a vibrant, coastal setting with constant visibility from both locals and tourists.

Property Type:

Retail

Date on Market:

2026-02-07

Chula Vista Retail for Lease

30,000 cars per day at intersection of Broadway and J St.

Date on Market:

2025-06-11

Solana Beach Retail for Lease - North Beach Cities

Second Floor Creative Office Space Facing S Cedros Ave. Available now for Sublease (Expires August 31st, 2026) or Direct Deal. High end creative space. Reception, Conference Room, Break/Kitchen area, Storage/IT, 2 private offices, open creative space. Brand new built in cabinets with granite countertops. Reserved Parking in Rear of the Project Operable Windows Throughout Polished Concrete Floors High exposed ceilings HVAC Please contact Jason Smithson for information or showing. 858 361-1195 Do not disturb tenant.

Date on Market:

2025-11-18

San Diego Retail for Lease - PB/Rose Canyon/Morena

Rare Second-Generation Restaurant Space with Dedicated Parking 1221 Garnet Avenue presents a rare leasing opportunity in the vibrant heart of Pacific Beach—one of San Diego’s most active and iconic coastal neighborhoods. This ±3,977 square foot, second-generation restaurant space offers a fully built-out layout, significantly reducing startup time and costs for incoming operators. Strategically located along Garnet Avenue, Pacific Beach’s main retail corridor, the property benefits from exceptional visibility, heavy vehicular and pedestrian traffic, and a high-profile presence just blocks from the beach. The site is positioned adjacent to the soon-to-open Grocery Outlet, adding to the area’s already strong daily foot traffic. A standout feature of this offering is the 13 exclusive-use parking stalls, a rare and highly desirable amenity in this dense coastal market. The space is ideally suited for a full-service restaurant, fast-casual concept, or specialty food and beverage use looking to capitalize on the area's strong daytime and evening populations.

Date on Market:

2025-05-28

San Diego Office, Retail for Lease - Downtown

Ground Floor Office/Retail Space Available in Downtown San Diego The Julia Position your business at the heart of San Diego’s vibrant downtown with this ±2,633 SF ground-floor retail or office space at The Julia. Located on bustling C Street between 3rd and 4th Avenue, this prime location offers exceptional visibility and signage opportunities directly adjacent to the iconic US Grant Hotel. Key Features: Size: ±2,633 SF Prominent linear frontage on C Street with strong pedestrian and transit traffic High-profile signage potential in a dynamic urban setting Steps from the Trolley Line, Petco Park, and numerous dining and entertainment venues One block from the transformative Campus at Horton, the largest adaptive reuse project in the U.S. Dense surrounding population: over 95,000 employees and 103,000 residents nearby Close proximity to major developments including Seaport Village, RADD life sciences campus, and the San Diego Convention Center

Date on Market:

2026-05-04