142 Storefront Properties for Lease in San Diego, CA, USA

National City Retail for Lease

Unlock the potential of your business with this retail opportunity on bustling Highland Avenue in the heart of National City. Surrounded by national retailers like Wal-Mart and Dollar Tree, this high-visibility space is perfectly positioned to capture steady foot traffic and daily drive-by exposure.

Date on Market:

2026-04-23

San Diego Retail for Lease - Park East

Date on Market:

2024-03-15

San Diego Office for Lease - Downtown

Creative Office Space For Lease! The space consist of 3,650 SF with three private offices, 1 conference, large kitchen/break room, reception/waiting area, rich hardwood flooring, exposed ceiling, and 10' ceiling height. Located in the Heart of Gaslamp Quarter, the property is within walking distance of the finest restaraunts, shops, and venues in the city. One block away from Petco Park and close proximity to the San Diego Convention Center and Rady Shell.

Property Type:

Retail

Date on Market:

2025-03-26

San Diego Office/Retail for Lease - PB/Rose Canyon/Morena

The Franco Realty Group is proud to exclusively present for lease the commercial suites located at 751-63 Turquoise Street. This property has plenty of onsite parking and is walking distance to Tourmaline Beach. There is plenty of onsite parking and excellent signage along Turquoise Street. The property is made up of 4 various boutique office and retail units. Please call us today for an updated list of our vacancies.

Property Type:

Retail

Date on Market:

2025-09-22

San Diego Office for Lease - Downtown

Property Type:

Retail

Date on Market:

2025-03-03

La Jolla Office/Retail for Lease

Situated in the heart of “the Jewel” on Ivanhoe Avenue, just minutes from La Jolla’s highly coveted Prospect Street, this premier office opportunity is surrounded by distinctive dining, luxury shopping and world class hotels and homes. This unique site is positioned to capture the strong local demographics while also drawing from La Jolla’s thriving tourism industry. La Jolla Pacific Building is a two-story office / retail building with 24-hour building access, HVAC, and high demand parking. With street level retail and second floor office space, the property is equipped with prominent building signage for great brand exposure.

Property Type:

Retail

Date on Market:

2025-02-21

San Diego Retail for Lease - Downtown

The Hamilton Building was constructed of reinforced concrete with an Art Deco/Moderne design in 1928. Totaling approximately 20,000 rentable square feet, this four-story retail building is well located in Downtown San Diego within walking distance to the Gaslamp Quarter and Petco Park. Recent renovations include: new roof, elevator, stairwells, fire sprinklers, HVAC, glass windows, restrooms, electrical, plumbing, and a full seismic retrofit. Please contact listing agent for more information.

Date on Market:

2025-02-06

San Diego Retail for Lease - Uptown West/Park West

Date on Market:

2025-02-03

La Jolla Office/Retail for Lease - PB/Rose Canyon/Morena

Great North Pacific Beach / Bird Rock location on the corner of La Jolla Blvd. and Turquoise Street– just a block from the ocean! Positioned at the intersection in Pacific Beach/Bird Rock, this project is perfect for service-oriented tenants looking to capitalize on the year-round beach traffic as well as the dense population of locals surrounding the property. Located in the heart of the Pacific Beach/La Jolla community in San Diego. The area benefits from high foot traffic, especially in the summer.

Property Type:

Retail

Date on Market:

2025-01-27

San Diego Retail for Lease - Downtown

Highly coveted Gaslamp location at Sixth Ave & Island Ave Space features 12’ to 14’ ceilings, dedicated restroom, storage closet and patio area in rear of premises Located in one of the most sought after entertainment and retail corridors in Southern California, and aligned with Campus at Horton brining over 4,000 jobs to Downtown Just steps to Petco Park and San Diego Convention Center with a combined 3 million annual attendees Surrounded by growing Downtown office, residential, and hotel markets - 10,512 residential units & 7,396 hotel rooms within 0.5 mi Immediate proximity to Seaport Village, the Embarcadero, East Village, and Little Italy

Date on Market:

2025-01-14

San Diego Retail for Lease - PB/Rose Canyon/Morena

Date on Market:

2022-10-07

San Diego Retail for Lease - Downtown

Date on Market:

2024-11-06

San Diego Retail for Lease - Uptown West/Park West

Single story 1930s vintage commercial frontage. The building has concrete walls and floors. The roof is arched steel trusses with exposed wood ceilings. Roof, skylights, and flashings were replaced in 2022. Lease term negotiable from 1 - 5 years. Located on the border of Hillcrest/North Park. If interested please contact Pablo Becerril at (619) 249-2770 or pablo@phillipsrealtyinc.com.

Date on Market:

2025-09-12

San Diego Office/Retail for Lease - Southeast San Diego

This exceptional retail/office space offers an unbeatable location within a highly walkable 81,000 SF neighborhood center, surrounded by strong co-tenants including Starbucks, Food 4 Less, Wells Fargo, and Subway. The property’s convenient access to the 94 and 805 freeways enhances visibility and customer flow, while pylon signage provides added exposure to high traffic counts. Ample parking ensures ease of access for both tenants and customers, making this space ideal for a variety of business uses. This is a prime opportunity to join a thriving center in a vibrant community.

Property Type:

Retail

Date on Market:

2024-10-22

San Diego Office/Retail, Retail for Lease - College Area

Prime corner retail space located on University Ave Phenomenal signage with maximum visibility - building and billboard opportunity Space features large open space, roll up door, and restrooms

Date on Market:

2025-10-07

San Diego Office/Retail for Lease - Old Twn/S Arena/Pt Loma

Fantastic opportunity to become Point Loma’s newest retail tenant! Ample on-site parking, approximately 120 spaces Anchored by Smart & Final, O’Reilly, and Michaels - strong retail sales & high customer volume Pylon signage and building signage opportunity High visibility and traffic counts - over 27,000 vehicles per day Directly across the street from Loma Square - Sprouts, CVS, Home Goods, Ulta, and more Ease of access to I-5 via Rosecrans St. or Pacific Hwy Close proximity to Liberty Station and San Diego Airport (over 15 million annual passengers) Adjacent to The Post - proposed 230,000 SF urban office campus Pride of ownership

Property Type:

Retail

Date on Market:

2025-04-14

Chula Vista Flex for Lease

This property offering for sale or for lease consists of an approximately 9,000 SF retail / flex building on a .84 acre lot represents a sale offering that may appeal to a very broad range of interested parties including single tenant retail or industrial or specialty occupiers that value abundant parking on a freestanding and fence-able lot. The location is adjacent to the heavily trafficked retail corridor of Palomar Avenue with close proximity to the 5 freeway and walking distance to the Palomar Street Transit and Trolley center and other major retailers such as Target and Costco.

Property Type:

Retail

Date on Market:

2024-01-22

La Mesa Office for Lease - East County

Property Type:

Retail

Date on Market:

2026-02-04

San Diego Office for Lease - Downtown

Property Type:

Retail

Date on Market:

2024-10-01

San Diego Office for Lease - Downtown

Fully remodeled Historic building in the heart of the Gaslamp district. Built in 1873, it was originally a one story building. However, now the building has seen tremendous changes and it is one of the well-acclaimed architectural monuments in San Diego. It is a classic example of architectural reviving of the classical and the Victorian era.

Property Type:

Retail

Date on Market:

2026-02-04

San Diego Retail for Lease - Southeast San Diego

Perfect for creative entrepreneurs, small retailers, or light food/beverage concepts seeking an authentic San Diego location, this 1,539 sq ft space in a 1946-built building blends industrial zoning with street-facing retail potential. With signage visibility, two parking spaces, and a negotiable lease in an M-zoned district, the property offers flexibility in use. Located in the heart of Barrio Logan, you’ll benefit from a community known for its artistic culture, diverse commerce, and rising foot traffic.

Date on Market:

2025-09-19

San Diego Retail for Lease - Downtown

Capital Growth Properties is elated to offer prime retail signage opportunities along Fifth Avenue. This retail space, located in the heart of the Gaslamp Quarter, is surrounded by San Diego’s premier restaurants and retailers and is within walking distance of the San Diego Convention Center. For more information, contact leasing agent Todd Law below!

Date on Market:

2022-02-25

La Mesa Office/Retail for Lease - East County

Property Type:

Retail

Date on Market:

2025-10-09

Del Mar Office/Retail for Lease - North Beach Cities

Property Type:

Retail

Date on Market:

2025-09-02