189 Storefront Properties for Lease in South Carolina, USA

Greer Retail for Lease - Rt 101 Corridor

Reedy River Retail at SVN | Palmetto is pleased to present ±11,900 SF of new construction multi-tenant retail space available at 1963 SC101 in Greer, SC. This development sits on ±3.33 acres in one of the Upstate’s fastest-growing corridors, offering excellent visibility and accessibility with full access on SC-101 and a secondary ingress proposed onto Rogers Bridge Road. The property benefits from strong traffic counts and proximity to national retailers, making it ideal for retail, medical, or office users seeking a prominent location in a high-demand market. The property will be delivered in Warm Grey Shell condition in 2026, featuring HVAC in place and flexible layout options ready for tenant-specific buildout. Key Highlights: Proposed Drive-thru endcap Available Lease Rate: ±$30–35/SF NNN Space Available: ±1,700–11,900 SF Traffic Count: ±27,000 VPD on SC-101 Parking: ±87 spaces (±3.64/1,000 SF)

Date on Market:

2025-11-14

Greenville Industrial for Lease - Western Greenville County

121 Osage Drive is a brand-new industrial/flex space in a high-growth Greenville submarket. The ±25,600 SF metal building is divisible into four suites, each with dedicated storefront entrances and window lines, allowing for customized office build-outs. With eight dock-high doors and four 12’ x 14’ roll-up doors, the facility is designed for efficient logistics and operational flow. Tenants will benefit from 23-foot clear heights, 3-phase power, and a robust 6-inch concrete slab suitable for heavy equipment and storage. Located adjacent to Donaldson Airport and minutes from I-185 and I-85, the site offers excellent access to regional transportation networks and is surrounded by major industrial users including Lockheed Martin and Michelin. The property’s inclusion in an Opportunity Zone may offer additional incentives for qualifying tenants. Whether for distribution, light manufacturing, or flex office use, 121 Osage Drive delivers modern infrastructure and strategic positioning in one of the Southeast’s most dynamic industrial markets.

Date on Market:

2025-11-10

Charleston Office/Retail for Lease - Downtown Charleston

Positioned on a prominent corner lot in the heart of Charleston’s rapidly emerging NoMo District, 716 Meeting Street offers a rare opportunity for businesses seeking a distinctive, high-visibility office environment. This two-story boutique office building combines character and convenience, making it ideal for creative firms, technology companies, and high-end service providers that value image, accessibility, and exposure. Its corner positioning provides excellent signage opportunities and continuous visibility along one of downtown Charleston’s most active corridors. Inside, tenants will appreciate the efficient floorplans, abundant natural light, and a professional yet creative atmosphere that enhances both client impressions and employee experience. The building’s scale makes it perfectly suited for companies seeking a stand-alone identity rather than a shared multi-tenant complex. Located among some of Charleston’s most exciting new developments, restaurants, and innovative businesses, 716 Meeting Street offers the energy of a growing district with the convenience of downtown access.

Property Type:

Retail

Date on Market:

2025-11-03

Charleston Retail for Lease - Downtown Charleston

59 Broad Street offers a rare opportunity to lease high-visibility retail/restaurant space in Charleston's iconic Broad Street corridor. Located within a three-story mixed-use building that will soon undergo exciting facade renovations, this suite offers exceptional foot traffic, historic charm, and proximity to some of downtown Charleston’s most sought-after dining, retail, and professional destinations. Ideal for an intimate restaurant, wine bar, coffee shop, etc; owner is willing to provide TIA to assist with the upfit cost for qualified operators. The building will feature an elegant façade with a folding door system so that the entire storefront can be opened up to Broad St on nice days. The interior offers a flexible layout ready to be tailored to a tenant’s specific needs. The first two floors, each just over 1600sf are connected by both elevator and rear stairwell, and allows operates a seamless two-story layout opportunity. Situated on one of the city’s most prestigious and walkable streets, 59 Broad provides a premier address with convenient access to nearby neighborhoods, government buildings, and tourist hubs.

Property Type:

Office

Date on Market:

2025-06-13

Greenville Office for Lease - Greenville CBD

Suite 200 at 245 N. Main Street offers a rare opportunity to lease premier Class A office space in one of Greenville’s most active commercial corridors. Located directly above Sushi Go and across from the Hyatt, the property enjoys exceptional visibility at a high-traffic intersection with dual entrances—one private street-level entry on Main Street with door signage and another on College Street with elevator access. The interior features exposed brick, high ceilings, wood floors, and expansive windows that bring in abundant natural light. The layout includes a large open area for workstations, five private offices or conference rooms, a breakroom/dining area, three restrooms, a phone booth, reception, and multiple storage and IT closets. Architectural details such as exposed wooden beams and window shades add warmth and character to the space. Surrounded by more than 70 restaurants and retailers within a one-mile radius, the location supports both employee convenience and client engagement. Monthly parking options are available nearby, and the walkable environment connects tenants to Greenville’s cultural, dining, and business destinations. This suite is ideal for firms seeking a professional presence with modern finishes and strategic access to the city’s amenities.

Property Type:

Retail

Date on Market:

2025-10-17

Anderson Flex for Lease - Anderson County

Palm Plaza Flex offers a rare opportunity to lease versatile flex and warehouse suites in a highly visible and accessible location along North Main Street in Anderson, South Carolina. With ±29,400 vehicles per day and proximity to both Downtown Anderson and Anderson University, this property is ideally positioned for businesses seeking convenience, exposure, and operational efficiency. Tenants benefit from prominent pylon and building signage options, multiple ingress/egress points, and ample parking with ±120 spaces on site. Located just 2.4 miles from Downtown Anderson and 2.5 miles from Anderson University, the property is surrounded by national retailers and local favorites including Whataburger, Dunkin’, QT, and Casa Fuentes. The area’s retail density and traffic counts make Palm Plaza Flex a strategic choice for businesses looking to grow their footprint in a thriving commercial corridor.

Property Type:

Retail

Date on Market:

2025-10-07

Anderson Retail for Lease - Anderson County

3014–3016 N. Main Street offers multiple retail suites for lease in one of Anderson’s most established retail corridors. Located along N. Main Street/Clemson Boulevard with ±29,400 vehicles per day, the property provides excellent visibility, pylon and building signage, and ample parking (±120 spaces). Tenants benefit from easy access, multiple ingress/egress points, and proximity to national retailers, restaurants, and banks; just ±2.5 miles from Anderson University and downtown.

Date on Market:

2025-10-07

Myrtle Beach Land for Lease - Downtown Myrtle Beach

100 x 150 Lot on US Hwy 501 with 30,000 cars a day under 45 MPH (According to DOT-Departmment Of Transporation Website ) Less than 1 mile from Walmart, Home Depot, Lowes Hardware and other major retailers And is a major Corridor into Myrtle Beach, SC. This Property is for Lease OR Build To Suit Call Trevor 843-997-0789

Property Subtype:

Agricultural

Date on Market:

2026-02-12

Charleston Office, Retail for Lease - Downtown Charleston

438 King Street is a three-story, ±10,673 square foot mixed-use building in the heart of Charleston’s historic Upper King Street corridor. Originally built in 1908, the property blends classic architectural character with modern updates. The building features large storefront windows, high ceilings, hardwood floors, and historic detailing throughout. Each floor includes access to outdoor patio or porch space, adding to its charm and usability. The property also includes 18 rare on-site parking spaces. The building is currently undergoing renovations and will be delivered in warm shell condition, offering a flexible canvas for retail, office, restaurant or hospitality. Property is also being offered for sale at $10,000,000.

Date on Market:

2025-10-02

West Columbia Office/Retail for Lease - Cayce/West Columbia

Property Type:

Retail

Date on Market:

2025-09-29

Myrtle Beach Retail for Lease - Downtown Myrtle Beach

Introducing a prime commercial space for lease at 514 Broadway St, Myrtle Beach, SC. This versatile property offers an ideal location for retail or office use, boasting ample square footage for customization, large storefront windows for maximum visibility, and a convenient open layout. With its high foot traffic and proximity to amenities, this space presents an unparalleled opportunity for businesses seeking a vibrant, dynamic environment. Discover endless potential and create a memorable presence in the heart of Myrtle Beach's commercial district. Welcome your customers to a space that embodies the allure of beachfront commerce!

Date on Market:

2025-09-24

Irmo Retail for Lease - Dutch Fork/Irmo

This 1,904-square-foot office and retail space is located in the heart of Irmo’s thriving Broad River Rd retail corridor with traffic counts of 14,600 vehicles per day. The space sits within the Publix shopping center, offering high visibility and steady foot traffic from surrounding national and local retailers. The property includes a flexible floor plan, making it ideal for professional services, boutique retail or customer-facing businesses. It is conveniently located near Dutch Fork schools and just minutes from Interstate 26, providing easy access for both customers and employees.

Date on Market:

2025-09-24

Clinton Retail for Lease - Laurens County

Reedy River Retail at SVN Palmetto is pleased to present a proposal for this property which is a rare opportunity located at the highly visible corner of Main Street and Musgrove Street, this ±2,200 SF retail space offers one of the best positions in downtown Clinton. Formerly home to a men’s clothing shop for many years and cigar lounge, the space is now vacant and ready for your new concept. With daily traffic counts of ±12,000 VPD on Carolina Avenue and ±10,000 VPD on Broad Street, this location delivers excellent exposure and steady customer flow. The property sits directly across from a public parking lot and the community stage, home to popular events like Rhythm on the Rails, which draws large crowds to the heart of downtown. Surrounded by a mix of national, regional, and local retailers including McDonald’s, True Value Hardware, Taco Bell/KFC, and numerous boutique shops, the property also benefits from nearby residential density, with apartments located directly behind the building. Major area traffic drivers include Presbyterian College, local dining establishments, and a vibrant cluster of downtown businesses. This versatile, blank space is ideal for an ice cream shop, coffee shop, boutique clothing store, or nearly any retailer seeking a flagship downtown Clinton presence. Situated along Clinton’s main retail artery, this is where locals come to shop, dine, and gather making it a prime opportunity for your next venture.

Date on Market:

2025-09-12

Travelers Rest Retail for Lease

Reedy River Retail at SVN Palmetto is pleased to present the opportunity to lease within this new construction retail strip center located on State Park Road in Travelers Rest, SC, just off HWY 25 (±28,200 VPD). Travelers Rest is a rapidly growing suburb of the Greenville, SC MSA with demand for more retail, coupled with a residential expansion and Furman University (±2,500 students). Surrounded by national retailers, such as WalMart, Chickfila, Starbucks and Chipotle this center is prepared for additional national, regional and local retailers.

Date on Market:

2025-09-10

Duncan Retail for Lease - Rt 290 Corridor

Reedy River Retail at SVN Palmetto is pleased to present an opportunity to lease space within Phase III of this HWY 290 (±37,500 VPD) retail development in Duncan, SC. The commercial and industrial growth of the Duncan and HWY 290 market continues to surpass expectations. This parcel is one of the last parcels that will have the ability for new retail development (unless future infill sites become available). Surrounded by high paying distribution & manufacturing professions, residential growth, I-85 and a Greenville Tech College campus, this retail opportunity is perfectly situated to capture it all.

Date on Market:

2026-01-26

Columbia Office/Medical for Lease - CBD

Property Type:

Retail

Date on Market:

2025-08-27

Ridgeland Office/Retail for Lease

The Terrace at Okatie Crossings is a brand new development with retail, restaurant, office & medical professional users. The buildings are directly on highway 170 with excellent visibility and close to Highway 278 Interchange Excellent location situated between Bluffton and Beaufort and surrounded by Sun City. The immediate area is experiencing unprecedented growth in both residential and commercial development. Other tenants include; Papa Murphy's Pizza, iCryo Recovery & Wellness, Hawg's Golf Carts & ATV's, Yamato Asian Grill, Sassy Nails, Marsh Point Dentistry, Heritage Pharmacy & Ochsner Novant Health.

Property Type:

Retail

Date on Market:

2025-08-20

Easley Retail, Flex for Lease - Outlying Pickens County

6932 Calhoun Memorial Highway in Easley, SC, is home to Cross Creek Plaza, a ~16,000?sf multi-tenant retail and flex center on a 1.57-acre lot with ~50 parking spaces and 370' of highway frontage. Built around 1970, the property offers a mix of retail, office, and light industrial/flex space, housing tenants such as Mattress Factory Direct, Jackson Hewitt, Western Union, and local boutiques. Its location on a busy corridor provides strong visibility and easy access, while its flexible layout and diverse tenant mix accommodate a range of small- to medium-sized businesses. The center benefits from signage opportunities, ample parking, and a strategic position within a busy retail submarket.

Date on Market:

2025-11-18

Greenville Retail for Lease - West Side Greenville

Date on Market:

2025-08-13

Batesburg-Leesville Retail for Lease - Outlying Lexington County

This charming space is located in a walkable area of downtown Batesburg that is experiencing renewed interest and revitalization with many stores opening down the street from this space and on adjacent downtown streets. This space is unique in that it includes a large outdoor area behind the building that may be used by the tenant to expand their business to include outside seating or to use for special events. This revitalization effort stems from planned upgrades like improved sidewalks, better lighting, and more parking spaces, addressing issues such as cracked sidewalks and abandoned buildings. The Town's 2020 revitalization master plan includes provisions for these enhancements, aiming to incorporate visual and performing arts into the historic downtown districts. On August 9th 2025 the Batesburg-Leesville Brew Fest will occur, with more festivals proposed in the upcoming months. In addition to physical improvements, the master plan proposes creating new parks and improved streetscapes to enhance the downtown area's appeal, along with strengthening connectivity to places like the historic Haynes Auditorium via a new linear park. The revitalization also seeks to position Batesburg-Leesville to attract new businesses and investors, boosting the local economy. This initiative is already showing signs of success, with new businesses opening in the revitalized areas. Batesburg-Leesville also recently received federal funding through the Safe Streets and Roads for All grant program to create an action plan for further walkability and safety improvements in both downtowns. These improvements will focus on traffic calming measures, wider sidewalks, and raised pedestrian crossings. While construction is still a ways off, these initiatives are generating positive momentum and a renewed sense of optimism in the community.

Date on Market:

2025-08-05

Greer Retail for Lease - Greer/Taylors

Date on Market:

2025-07-24

Hilton Head Island Office for Lease

Property Type:

Retail

Date on Market:

2025-11-12

Gaffney Retail for Lease - Cherokee County

Date on Market:

2025-06-23

Fort Mill Retail for Lease - Lancaster County

Positioned at the high-traffic intersection of Charlotte Highway and Indian Land, the Shoppes at 521 offers a prime office and retail opportunity in one of the fastest-growing corridors of Fort Mill, SC. This two-story Class B center combines visibility and convenience, making it ideal for businesses seeking strong regional connectivity. The property benefits from quick access to I-77 and SC-160, ensuring seamless travel to Charlotte and surrounding South Carolina communities. With household incomes averaging over $80,000 within a five-mile radius and a population exceeding 145,000, the area offers exceptional market potential. This is an opportunity to secure space in a thriving community where convenience, visibility, and growth converge.

Date on Market:

2025-06-06