173 Storefront Properties for Lease in South Carolina, USA

Greenville Land for Lease - Powdersville/Easley

Never developed level parcel with all utilities to site and offsite storm water retention already in place.

Property Subtype:

Commercial

Date on Market:

2025-08-26

Greenville Office/Retail for Lease - South Pleasantburg

Property Type:

Retail

Date on Market:

2025-11-03

Rock Hill Industrial for Lease - York County

2690 Commerce Drive is a 120,000-SF industrial building located just off I-77 with immediate interstate access via 3 existing exit ramps. New ownership is completing several upgrades including renovations of the existing office and bathrooms, construction of a new storefront, and ±1,021 sf spec office. The neighboring companies include Continental Tires, Atlas Copco, McKesson, La-Z-Boy, Energizer Batteries, Unique Loom, Mlily, DHL Supply Chain, NFI, and Logistics+.

Date on Market:

2025-04-01

Columbia Office/Retail for Lease - North Columbia

Extensive renovations are completed to restore the Laundry Building, the oldest surviving service building in the historic BullStreet District campus. The approximately 15,932 square foot adaptive reuse building will feature an event venue, expansive green spaces, and a dynamic tenant mix such as a restaurant, coffee shop / bakery, boutique fitness, and creative office. The Laundry event venue, set to be the flagship of the building, will be available for weddings and other rentals starting in December 2024. Located in the heart of the thriving BullStreet District behind the Babcock’s dining halls, the Laundry Building is an Italianate-influenced building dating back to 1883. The Laundry is adjacent to other service buildings like the Bakery that was part of the hive of industry which operated in the background to help support the mental asylum. The Laundry Building work includes a new standing seam metal roof, restoration of the historic clerestories, skylights and the cupola. Avant Holdings refurbished the historic exterior stairwell and original steel sash windows, opened up the bricked in windows and installed new historically compatible energy efficient windows, completed structural reinforcements, gently removed paint off the brick and granite windowsills, as well as performed brick pointing throughout. Most recent construction are high quality common area restrooms in the main lobby, plus an expanded lobby with an elevator lift as well as open flow stairs. All new infrastructure, parking, streetscaping and streetlights wrapping the Laundry is complete. The design features an open layout respecting the historic character of the Laundry Building with soaring ceilings, exposed antique heart pine wood beams, trusses, fire sprinkler lines and spiral ductwork. The interior is exposed brick, including a massive brick archway with a mix of historic plaster walls and sleek concrete floors throughout. Existing steel sash windows and restored window openings with new windows flood the space with natural light. The full one acre of land is mostly green space with beautiful trees offering endless possibilities for outdoor seating and amenities with the iconic Babcock Building as a focal backdrop. A conceptual layout is provided envisioning several tenants. The 181-acre BullStreet District is the largest urban redevelopment project on the East Coast and is South Carolina's first urban gigabit community, just one mile from the S.C. State House and several blocks from Main Street in downtown Columbia, S.C.

Property Type:

Retail

Date on Market:

2023-02-23

Greenville Office, Retail for Lease - South Pleasantburg

One-of-a-kind opportunity to lease first-generation office and retail space in a brand new mixed-use development just off S Pleasantburg drive near Interstate 385. The former Kimbrell’s at 20-22 Liberty Lane in the Pleasantburg Shopping Center is set to be redeveloped into a unique office, retail, and coworking concept. Currently in shell condition with ±1,000 to ±28,900 SF suites currently available, the space is flexible and can be configured to meet tenants’ individual needs.

Date on Market:

2024-11-12

Mount Pleasant Retail for Lease - East Islands/Mt Pleasant

The 510,208-square-foot open-air shopping destination is set on 51 acres with over 60 stores and restaurants, the Regal Palmetto Grande movie theater, the Hyatt Place hotel, and a beautiful greenspace activated with events. A curated mix of shopping, chef-driven dining, upscale accommodations, community-inspired events, and welcoming gathering spaces draw locals and visitors alike to soak up the luxury of Lowcountry Living and enjoy a day on the Towne.

Date on Market:

2026-01-09

Charleston Coworking for Lease - Downtown Charleston

Historic 460 King Street used to be home to Robinson Toy Store for decades. Since then, the first floor has served well as space for different restaurants and nightlife venues over the years. Currently, 460 King Street is home to Office Evolution on the 2nd floor... the very same space that the Robinson family used to store bicycles! If you ask, we still have bike tags from almost 100 years ago!

Property Type:

Retail

Date on Market:

2017-05-22

Yemassee Retail for Lease

Positioned at Exit 38 off Interstate 95, this high-visibility gas station and convenience store offers a prime location for operators seeking immediate exposure to one of the East Coast’s busiest travel corridors. The property benefits from a daily traffic count of approximately 41,992 vehicles and provides direct access to I-95 southbound, ensuring consistent customer flow from both local and transient traffic. The 5,413-square-foot convenience store features an open floor plan, ideal for flexible merchandising and potential integration of food and beverage services. Its strategic layout accommodates a variety of vehicle types, including cars, RVs, and delivery trucks, making it an attractive stop for tourists, commuters, and long-haul drivers traveling between Charleston, Hilton Head, and Savannah. Prominent roadside signage and excellent visibility further enhance brand recognition. This is an exceptional opportunity for businesses looking to establish or expand their presence in a high-traffic, growth-oriented corridor.

Date on Market:

2026-01-15

Iva Retail for Lease - Anderson County

624 E Front St., Iva, SC is a 2,700 square foot, move-in ready restaurant space in Grade A condition. The property is fully built out for food service and prepared for immediate operation with minimal upfront investment. Located approximately 3 miles from Crescent High School and benefiting from 4,700 vehicles per day (VPD), the property is ideally positioned to capture traffic before and after high school sporting events. The space is approved by the Anderson County Fire Department for a 96-person occupancy, making it suitable for a wide range of restaurant concepts.

Date on Market:

2026-01-09

Beaufort Office/Retail for Lease

Property Type:

Retail

Date on Market:

2025-12-17

Hartsville Retail for Lease

Position your business in Hartsville’s premier retail corridor at 1211 Retail Row, a vibrant destination anchored by Super Walmart and surrounded by leading national brands. Located just off South 4th Street and Highway 15, the property sits at the heart of the region’s dominant retail hub, featuring Lowe’s Home Improvement, fast-casual dining, and a dynamic mix of service providers. Hartsville is a thriving community with strong economic drivers, including major employers like Sonoco and Duke Energy, and educational institutions such as Coker University and the SC Governor’s School for Science and Mathematics. The area boasts steady population growth and rising household incomes, creating a solid foundation for retail success. With easy access to Florence (30 minutes) and Columbia (one hour), this location captures both local and regional traffic.

Date on Market:

2025-11-21

Lyman Retail for Lease - Upper Spartanburg County

229 Charlotte Hwy offers a prime retail location in the heart of Lyman’s rapidly expanding corridor. This recently renovated building features a modern exterior design with excellent visibility and multiple access points, creating an ideal setting for businesses seeking high exposure. Positioned along a major thoroughfare with approximately 23,600 vehicles per day, the property benefits from strong traffic flow and easy connectivity to I-85, placing Greenville and Spartanburg within convenient reach. The surrounding area is experiencing significant growth, with more than 3,000 new homes under development within a three-mile radius and the upcoming Shoppes at Pine Ridge introducing major retailers such as Publix, Tractor Supply, and Lowes Foods. Ample on-site parking and a strategic location near established businesses enhance customer convenience and drive consistent foot traffic. This property is well-suited for retail concepts looking to capitalize on a dynamic market and a thriving residential base.

Date on Market:

2025-11-19

Johns Island Retail for Lease - West Islands

Positioned along the high-traffic Main Road corridor, 685 Main Road offers a prime retail leasing opportunity in the heart of Johns Island. This ±5.89-acre site is approved for a ±16,000 SF retail center, with suites divisible to ±1,600 SF, allowing for flexible configurations tailored to service-oriented and retail tenants. The property benefits from excellent visibility and easy access, located just half a mile south of the River Road/Main Road intersection, with traffic counts reaching 28,000 vehicles per day. The site is zoned Rural Commercial (RC) under the Main Road Corridor Overlay District, supporting a wide range of uses including tire shops, vehicle repair, and general retail. Public water is available, and the site includes an onsite septic field. With strong demographics and proximity to Charleston’s expanding residential base, this location is ideal for tenants seeking high exposure and accessibility in a growing market. The two pad sites will be delivered graded with utilities, stormwater, and approved septic in place.

Date on Market:

2025-11-12

Columbia Retail for Lease - CBD

Located at 929 Gervais Street, this ±1,710 SF retail space is situated on the first floor with direct access to Gervais Street. The space has been renovated and features an open floor plan with exposed beams and brick walls, making it an ideal opportunity for retail use. This retail space is located in the center of Columbia’s downtown Vista district. The pedestrian-friendly Vista attracts locals and visitors alike with a dynamic mix of restaurants, bars, art galleries and specialty shops. Additionally, the area is convenient to the Central Business District, the SC State House and the University of South Carolina.

Date on Market:

2025-11-07

Myrtle Beach Land for Lease - Downtown Myrtle Beach

100 x 150 Lot on US Hwy 501 with 30,000 cars a day under 45 MPH (According to DOT-Departmment Of Transporation Website ) Less than 1 mile from Walmart, Home Depot, Lowes Hardware and other major retailers And is a major Corridor into Myrtle Beach, SC. This Property is for Lease OR Build To Suit Call Trevor 843-997-0789

Property Subtype:

Agricultural

Date on Market:

2025-10-06

Central Retail for Lease - Outlying Pickens County

- Suite S Available (1,600 SF)- Former Restaurant Space - Prime retail space in Walmart shadow center - New 150,000 SF AnMed campus is currently under construction right across Calhoun Memorial Hwy - New Ownership who desires to invest back into the property. - Co-tenants include Dollar Tree, Subway, Cricket Wireless, Mi Fiesta Grill, NAPA Paints, and Bricks & Minifigs - Monument signage available on Eighteen Mile Rd - Located at the Highway 123 and Eighteen Mile Road intersection, with full signalized access to Eighteen Mile Road. - Strategically positioned between Clemson University, City of Clemson, Southern Wesleyan University, Central and Pendleton - Clemson University 2025 Enrollment 29,545 students an increase of 12.8% over the previous 5 years. - Traffic Counts: Hwy 123 - 24,100 VPD & 18 Mile Rd - 7,500 VPD - Asking Rate: $16.00 SF NNN

Date on Market:

2025-08-29

North Myrtle Beach Retail for Lease

Located in the highly sought-after North Village Shopping Center. Long-term stability in a thriving shopping center. Tenants include Dollar General, Roses, Citi Trends, Honey Baked Ham, State Farm Insurance, and Miller Fitness High visibility and heavy foot traffic Convenient access to Hwy 17 and close proximity to local amenities High traffic count at over 39,000 VPD Don’t miss the chance to join a well-established retail hub in North Myrtle Beach.

Date on Market:

2025-02-17

Anderson Retail for Lease - Anderson County

Approximately 50,000 SF shopping center located on Highway 24 in a growing area with close proximity to Lake Hartwell. This property is located an an underserved + trade area + is ideal for a number of users.  Spaces Available: 4365 US 24- 2,400 SF of open space with one restroom. Ideal for retail or office user. $8/SF. 4365 US 24 Unit D- 1,200 SF of open space, could be used for retail or office user. $12/SF.

Date on Market:

2024-09-05

Loris Office/Retail for Lease - Outlying Horry County

Former Single Store, Renovated & Continuing To Be Renovated By Tenant Uses into (4) Four Retail/Office Spaces At the Premier Downtown Corner of the Town of Loris South Carolina 29569. Four Units of Space with Unit A currently leased to WingZone. Units B, C & D still available. Available Spaces are 1,850 SF for Unit B; 1,450 SF for Unit C; and 905 SF for Unit D. Please contact leasing agent for further details.

Property Type:

Retail

Date on Market:

2024-03-05

Lugoff Retail for Lease - Kershaw County

Newly built retail space on busiest road in Kershaw County.

Date on Market:

2025-11-25

Simpsonville Land for Lease - Mauldin/Fountain

9 Acres of property ideal for new commercial retail or entertainment. Long frontage available on rapidly growing W. Georgia Road in Simpsonville, SC. 1500 sq.ft. home sits on the property. Located adjacent to a new 48,000 sq. ft. Publix with 15,500 SF of fully leased shop space. Located at the intersection of W. Georgia Road and East Standing Springs Road. The property sits directly across from a Walmart Neighborhood Market and a 30,000 square foot GHS medical office building. An existing traffic signal benefits the site. West Georgia Road is one of Greenville’s fastest-growing residential areas. The area includes 19,000 households, with 2,000 units under construction or proposed. 20,000 VPD.

Property Subtype:

Commercial

Date on Market:

2025-12-16

Cheraw Office, Retail for Lease

Date on Market:

2021-12-20

Florence Land for Lease

Property Description Site : ±2 Acres Zoning: Unzoned Municipal Sewer: 12” on site side of S. Cashua Dr Municipal Water: 6” on opposite side of S. Cashua Dr Frontage: ± 550’ on Second Loop Traffic Counts: 26,100 VPD on Second Loop Road 13,100 VPD on S. Cashua Drive Population: 5 Mile Radius – ± 74,344 10 Mile Radius – ± 116,422 Available is the last remaining corner site at Florence’s most heavily travelled commercial inter-section, Second Loop Road and S. Cashua Drive. This commercial and commuter corridor is home to a variety of commercial entities including: professional and financial/banking services, medical office facilities, supermarkets, food and beverage and many national and local retail busi-nesses. South Cashua Drive is currently under construction to be converted to a four lane undi-vided highway that will serve residential and commercial developments to the south and west of the city. This unique ±2 acre development site fronts both Second Loop Road and S. Cashua Drive and is Available for Lease—$11,000/Month/Net

Property Subtype:

Commercial

Date on Market:

2018-01-10

Fort Mill Land for Lease - York County

With strong traffic flow, affluent demographics, and proximity to major distribution hubs, Regent Park stands out as a premier investment for developers and end-users alike. This is an exceptional chance to capitalize on Fort Mill’s sustained growth and dynamic retail environment.

Property Subtype:

Commercial

Date on Market:

2025-12-18