189 Storefront Properties for Lease in South Carolina, USA

Johns Island Retail for Lease - West Islands

Positioned along the high-traffic Main Road corridor, 685 Main Road offers a prime retail leasing opportunity in the heart of Johns Island. This ±5.89-acre site is approved for a ±16,000 SF retail center, with suites divisible to ±1,600 SF, allowing for flexible configurations tailored to service-oriented and retail tenants. The property benefits from excellent visibility and easy access, located just half a mile south of the River Road/Main Road intersection, with traffic counts reaching 28,000 vehicles per day. The site is zoned Rural Commercial (RC) under the Main Road Corridor Overlay District, supporting a wide range of uses including tire shops, vehicle repair, and general retail. Public water is available, and the site includes an onsite septic field. With strong demographics and proximity to Charleston’s expanding residential base, this location is ideal for tenants seeking high exposure and accessibility in a growing market. The two pad sites will be delivered graded with utilities, stormwater, and approved septic in place.

Date on Market:

2025-11-12

Columbia Retail for Lease - CBD

Located at 929 Gervais Street, this ±1,710 SF retail space is situated on the first floor with direct access to Gervais Street. The space has been renovated and features an open floor plan with exposed beams and brick walls, making it an ideal opportunity for retail use. This retail space is located in the center of Columbia’s downtown Vista district. The pedestrian-friendly Vista attracts locals and visitors alike with a dynamic mix of restaurants, bars, art galleries and specialty shops. Additionally, the area is convenient to the Central Business District, the SC State House and the University of South Carolina.

Date on Market:

2025-11-07

Central Retail for Lease - Outlying Pickens County

- Suite S Available (1,600 SF)- Former Restaurant Space - Prime retail space in Walmart shadow center - New 150,000 SF AnMed campus is currently under construction right across Calhoun Memorial Hwy - New Ownership who desires to invest back into the property. - Co-tenants include Dollar Tree, Subway, Cricket Wireless, Mi Fiesta Grill, NAPA Paints, and Bricks & Minifigs - Monument signage available on Eighteen Mile Rd - Located at the Highway 123 and Eighteen Mile Road intersection, with full signalized access to Eighteen Mile Road. - Strategically positioned between Clemson University, City of Clemson, Southern Wesleyan University, Central and Pendleton - Clemson University 2025 Enrollment 29,545 students an increase of 12.8% over the previous 5 years. - Traffic Counts: Hwy 123 - 24,100 VPD & 18 Mile Rd - 7,500 VPD - Asking Rate: $16.00 SF NNN

Date on Market:

2025-08-29

Anderson Retail for Lease - Anderson County

Approximately 50,000 SF shopping center located on Highway 24 in a growing area with close proximity to Lake Hartwell. This property is located an an underserved + trade area + is ideal for a number of users.  Spaces Available: 4365 US 24- 2,400 SF of open space with one restroom. Ideal for retail or office user. $8/SF. 4365 US 24 Unit D- 1,200 SF of open space, could be used for retail or office user. $12/SF.

Date on Market:

2024-09-05

Columbia Retail for Lease - Forest Acres

Date on Market:

2024-05-28

Loris Office/Retail for Lease - Outlying Horry County

Former Single Store, Renovated & Continuing To Be Renovated By Tenant Uses into (4) Four Retail/Office Spaces At the Premier Downtown Corner of the Town of Loris South Carolina 29569. Four Units of Space with Unit A currently leased to WingZone. Units B, C & D still available. Available Spaces are 1,850 SF for Unit B; 1,450 SF for Unit C; and 905 SF for Unit D. Please contact leasing agent for further details.

Property Type:

Retail

Date on Market:

2024-03-05

Cheraw Office, Retail for Lease

Date on Market:

2021-12-20

Daniel Island Retail for Lease

Simmons Park is an upscale mixed-use development featuring 5,550 SF of street-front retail beneath 269 luxury apartment residences. Positioned in the heart of Daniel Island’s thriving commercial district, surrounded by an affluent customer base with $118,187 median household income within a 5-minute drive. 2,285 SF second generation fitness opportunity for lease in a highly visible endcap location, offering abundant natural light and enhanced storefront exposure.

Property Type:

Multifamily

Date on Market:

2026-03-03

Bamberg Office/Retail for Lease

Property Type:

Retail

Date on Market:

2026-02-13

Lyman Retail for Lease - Upper Spartanburg County

• ±9,000 SF retail center • Expected delivery in Q1 of 2027 • Drive-thru End-Cap capabilities • Warm vanilla shell delivery • Located in High Growth Corridor • Excellent visibility on Highway 29 • ±26,300 VPD • ±11 miles to Downtown Spartanburg • ±16 miles to Downtown Greenville • Call Broker for Pricing

Date on Market:

2026-03-09

Moncks Corner Retail for Lease - Outlying Berkeley County

Date on Market:

2026-02-02

Fort Mill Land for Lease - York County

With strong traffic flow, affluent demographics, and proximity to major distribution hubs, Regent Park stands out as a premier investment for developers and end-users alike. This is an exceptional chance to capitalize on Fort Mill’s sustained growth and dynamic retail environment.

Property Subtype:

Commercial

Date on Market:

2025-12-18

Irmo Land for Lease - Dutch Fork/Irmo

±5.21-acre subdivisible land parcel for retail, restaurant, or medical use

Property Subtype:

Commercial

Date on Market:

2025-10-10

Charleston Land for Lease - West Ashley

5+/- upland acres available for ground lease at the intersection of West Ashley Circle and Bees Ferry Road in a growing area of Charleston, SC. There are 85,000 residential units in the 5-mile radius, with multiple large communities just beginning to take shape in the immediate market.  Sharing access and traffic with the only Wal-Mart in the sub-market, West Ashley Circle is the primary retail destination which carries traffic from the residential communities back to 526 and the City of Charleston.

Property Subtype:

Commercial

Date on Market:

2025-03-10

Union Retail for Lease - Union County

Nearly 4,200 sq feet of jaw-dropping space! This space is for RENT only, NOT for sale. Located at 110 E Main St, Union, this well-maintained building was established in 1880! Available for rent at $2,500/Month. The main floor, basement, 2 large loft areas, 2 bathrooms, and utility space are all included and available for use. The original hardwood floors, exposed brick, arched windows, and built-in shelves only add to its character and make the space perfect for a variety of uses. Do you have dreams of running your business out of a historic, charming environment? Event space, antique mall, photography studio, the options are ENDLESS! While Union grows and Main Street comes to life, secure your spot to house your business in a unique place like 110 E Main St... ****Tenant will be responsible for their own utilities. Tenant may sublease the space. Space can not be used for gatherings/parties.****

Date on Market:

2025-10-21

Easley Coworking for Lease - Outlying Pickens County

This shared office space has 3 fully furnished offices, a waiting & reception area, staff lounge, bathroom, parking lot, electric/water/Wifi is included. We have it professionally cleaned 2x/month. The space is currently occupied by therapists (social workers). Complimentary professions will be considered. Rent is determined by how many days/week you want. It's $145/month for 1 day/week. (4 or 5 days/month depending on the month) It comes out to be about $30-$35/day. For example, if you want it 2 days/week, Tues and Thurs, that would be 8 or 9 days/month (depending on the month) or $290/month. It is month-to-month. No deposit required. Again, all utilities and internet is included.

Property Type:

Retail

Date on Market:

2024-09-24

Fountain Inn Retail for Lease - Mauldin/Fountain

Strategically positioned, this location provides direct access to I-385 and offers exceptional connectivity to the Greenville market. With a high daily traffic count of 53,000 vehicles per day, this site ensures excellent exposure and visibility, making it an ideal investment for businesses seeking access to the Fountain Inn community. It presents a move-in-ready opportunity, perfect for fast-food or retail restaurants.

Date on Market:

2024-04-29

Westminster Retail for Lease

Date on Market:

2021-08-18

Awendaw Office/Retail for Lease - E Charleston County

12 Units of 1,200SF each available for retail services and office uses Join Tractor Supply and Dollar General

Property Type:

Retail

Date on Market:

2018-06-20

Newberry Retail for Lease

Explore an exceptional leasing opportunity at 1930 Main St. in Newberry, SC! This prime property offers a strategically located space with high visibility, ideally suited for retail or free-standing building businesses. With a modern and adaptable layout, ample parking, and responsive management services, this property is well-prepared to support the needs of your retail concept. Whether you're in search of a space for a single retail storefront or a larger free-standing building, this property offers the flexibility and amenities to accommodate a variety of business needs. Take advantage of this opportunity to establish a prominent retail presence in this sought-after commercial locale and unlock the full potential of 1930 Main St.

Date on Market:

2015-09-16

Sumter Retail for Lease

Uncover a remarkable leasing opportunity at 7 N. Guignard Dr. in Sumter, SC! This versatile property offers a prime location with high visibility, making it an ideal fit for retail or strip center businesses. Featuring a modern and adaptable layout, ample parking, and responsive management services, the space is well-prepared to meet the needs of your retail concept. Whether you require a space for a single retail storefront or a larger strip center, this property provides the flexibility and amenities to accommodate a variety of business needs. Seize the chance to establish a prominent retail presence in this sought-after commercial hub and maximize the potential of 7 N. Guignard Dr.

Date on Market:

2018-04-12