49 Life Science Properties for Lease in Boston, MA, USA

Cambridge Office, Retail for Lease - Mid-Cambridge/Harvard Sq

The Abbot at 18-24 Brattle Street presents a once-in-a-generation opportunity to occupy the most iconic building in the heart of Harvard Square, the epicenter of Cambridge, Massachusetts. Future tenants are invited to discover the tremendous redevelopment potential of this iconic property through a blend of historic preservation with modern amenities. World-class academic institutions, top tech and life science companies, vibrant neighborhoods, and rich cultural diversity surround this dynamic property. Completely renovated from the inside out, suites on the second and fourth floors are immediately available for lease. The building's diverse tenant mix includes creative and professional businesses and national tenants, such as Starbucks, Cava, and F45 Training. Occupancy terms are negotiable, with lease rates available upon request. Building tenants enjoy state-of-the-art HVAC, private outdoor space, operable windows, and more. Historical and cultural offerings, cobblestone streets, and a unique blend of over 350 dining, retail, and entertainment options within a quarter-mile encompass The Abbot. This section of Cambridge is one of the most iconic locations in the market and one of the most accessible. Situated directly across the street from Harvard Square Red Line Station, the third-most active station in the area, tenants have access to over 23,000 daily riders. The Abbot boasts unparalleled traffic and amenities, making it a draw for customers, businesses, and retailers alike.

Date on Market:

2026-03-10

Boston Industrial for Lease - Seaport

310-312 North Avenue is a class B industrial building that offers refrigerated industrial condominiums in Boston, MA. The 48,882 square foot building has 26,000 square feet, split between 2 condos, available for sale or lease. The building is conveniently located near two bus lines and eight-minutes away from the Boston Logan International Airport, providing easy access for commuting. Additional to the commuter options, the building Is also within a one to eight-minute drive to eight hotels in the area. Tenants can enjoy industrial spaces with cross docks, refrigeration, and redevelopment opportunities. Employees will find themselves within driving distance of restaurants and banks.

Date on Market:

2024-06-20

Cambridge Office for Lease - E Cambridge/Kendall Sq

Date on Market:

2025-07-15

Watertown Office for Lease

Date on Market:

2026-02-27

Medford Office/Medical for Lease - Medford/Malden

One Cabot Road is a four story, ±316,233 SF class A office building located in the thriving community of Medford, Massachusetts. The property recently underwent a $16.9 million amenity upgrade and now features a new lobby lounge, coffee lounge, new fitness center and locker rooms, expansive outdoor patio and a full-service cafe.

Property Type:

Office

Date on Market:

2024-02-23

Cambridge Retail for Lease - Mid-Cambridge/Harvard Sq

The Abbot is the epicenter of Harvard Square. This iconic redevelopment is an irreplaceable world class retail and office destination in the heart of Harvard Square.

Property Type:

Office

Date on Market:

2026-03-17

Cambridge Office, Flex for Lease - Mid-Cambridge/Harvard Sq

Date on Market:

2025-09-29

Cambridge Retail for Lease - E Cambridge/Kendall Sq

Immediately north of the site is Cambridge Crossing, a new 43-acre development located at Lechmere Station home to Philips, Bristol Meyers Squibb, REI, Tatte, and Lamplighter Brewing

Property Type:

Office

Date on Market:

2025-11-17

Chelsea Office for Lease - Chelsea/Revere

Tons of area amenities within walking distance from the property. Highly attentive property management. Cost effective office space that Landlord is willing to build out for potential tenants to their required specs. Immediately accessible to the commuter train station, just one stop to North Station. Bus service to Wellington (orange), Haymarket (green) and Wonderland (blue) immediately accessible. Boston Logan International Airport just minutes away. Easy on/off Routes 1, 93 and 16.

Date on Market:

2025-09-02

Boston Office for Lease - Seaport

Seaport Circle is a mixed-use development featuring 650,000 square feet of life science research and office space in Boston's most prominent life science cluster. The project is pursuing LEED Platinum designation, with a 90% reduction in natural gas use. The two-tower design will provide flexible floor plates ranging from 25,000-75,000 square feet. In addition to state-of-the-art Class A lab and office space, the building will include best-in-class tenant amenity spaces and approximately 5,000 square feet of retail space. Seaport Circle will also include a 15,000 SF stand-alone South Boston Waterfront Job Training Pavilion (the Pavilion) with an ambitious mission focused on training for skilled jobs in life sciences and adding talent to the pipeline of opportunity in the Boston area’s exploding life science sector.

Date on Market:

2023-02-06

Charlestown Multiple Space Uses for Lease - Charlestown/East Boston

Date on Market:

2025-06-05

Boston Retail for Lease - Longwood/Fenway

Property Type:

Office

Date on Market:

2025-09-16

Allston Office for Lease - Allston/Brighton

Proposed Office/Lab Development. Allston Yards is just one rail stop away from the bustle of downtown but with an energy and buzz all its own. Whether it’s an iced coffee after hot yoga or a quick bite before a long night with friends, you can have it all. Join our fresh new community crackling with potential. Here at Allston Yards, we live well, work hard, and never miss a beat.

Date on Market:

2019-05-01

Boston Office, Office/Medical for Lease - Midtown

Great opportunity to customize your next office in a classic & iconic Boston building. Perfect for office, medical, tech, research, lab and more! Visit our website to learn more! www.75kneeland.com

Date on Market:

2025-06-17

Boston Office for Lease - Newton/Brookline

Date on Market:

2025-12-09

Allston Office/Medical for Lease - Allston/Brighton

Property Type:

Flex

Date on Market:

2024-09-18

Somerville Office for Lease - Somerville/Everett

101 South Street is speculative lab building in the Boynton Yards industrial area of Somerville, MA. Located adjacent to Union Square and only one mile from Kendall Square, the City of Somerville plans for Boynton Yards to be redeveloped into a vibrant, mixed-use district comprised of lab, office, multifamily and neighborhood retail and community arts space.

Date on Market:

2025-04-03

Cambridge Office for Lease - Mid-Cambridge/Harvard Sq

Prime location in the heart of Kendall Square, known for its vibrant life sciences and biotech community. This property is part of the Osborn Triangle complex, which includes premier office and lab spaces.

Date on Market:

2024-09-19

Cambridge Flex for Lease - Mid-Cambridge/Harvard Sq

Date on Market:

2024-08-08

Watertown Office for Lease

The Arsenal on the Charles is being transformed into a an innovative life sciences campus that will feature three new buildings. Alexandria's fully-amenitized campuses are innovatively designed to build meaningful and valuable communities.

Date on Market:

2025-09-12

Charlestown Flex for Lease - Charlestown/East Boston

Date on Market:

2023-07-26

Cambridge Office for Lease - E Cambridge/Kendall Sq

Date on Market:

2023-03-22

Cambridge Office for Lease - E Cambridge/Kendall Sq

Date on Market:

2023-12-07

Cambridge Office for Lease - E Cambridge/Kendall Sq

Date on Market:

2022-07-18