103 Life Science Properties for Lease in Pennsylvania, USA

Fort Washington Office for Lease - Ft Wash/Spring House

45,000 SF office / medical building. Located at Fort Washington Interchange of the PA Turnpike (I-276). Ideal spaces for any professional use. Elevator served building. Across the street from Life Time Fitness. Close proximity to numerous dining, shopping, and lodging.

Date on Market:

2025-05-28

Norristown Industrial for Lease - Norristown/Valley Forge

Date on Market:

2025-05-20

Pittsburgh Office for Lease - Parkway East Corridor

• Unique retail opportunity at the forefront of the RIC development and Hazelwood Green neighborhood • 1,400 – 2,000 sf of first-floor retail space • Perfect for café, luncheonette, or boutique eatery • Plenty of natural light • Adjacent to University of Pittsburgh’s Pitt BioForge and the Mill 19 research and development hub • Proximity to the Round House • Future developments include: Lytle Street Apartment Building, Pittsburgh Steelers multi-sport facility, and two acres of outdoor green space for events & community use

Date on Market:

2025-05-14

Philadelphia Retail for Lease - University City

Property Type:

Hospitality

Date on Market:

2025-04-07

King Of Prussia Office for Lease - King of Prussia/Wayne

Property Type:

Flex

Date on Market:

2025-04-01

Malvern Office for Lease - Exton/Whitelands

Adjacent to Malvern Interchange of PA Turnpike. Easy access to King of Prussia & Downingtown. Close proximity to Rt-29, Rt-202, and Rt-30. Adjacent to restaurants and supporting retail.

Date on Market:

2025-03-17

Pittsburgh Retail for Lease - Oakland

New Construction 350,000 Class (A) Building The subject property is located at the highly coveted corners of Baum Blvd/ Morewood Ave “&” Centre Ave/Morewood Ave, adjacent to UPMC Shadyside Hospital and world renowned Hillman Cancer Center. 5051 Centre Ave is the gateway to Oakland, which is the educational and hub of Pittsburgh and home to the University of Pittsburgh and Carnegie Mellon University. The subject property sits at the convergence of Bloomfield and Shadyside, two of Pittsburgh’s most dynamic urban neighborhoods. This area showcases boutiques, shops and galleries that mingle with national retailers in a neighborhood of tree-lined streets, historic homes and distinctive restaurants. The large residential area includes beautifully restored Victorian mansions alongside modern homes and condos. Located at the primary signalized intersections of Baum Blvd/ Morewood Ave & Centre Ave/Morewood Ave. The subject property benefits from tremendous traffic volumes along with great visibility and ease of access in a strong urban business district and a densely populated urban residential environment. Baum Boulevard and Centre Ave is among the most heavily traveled urban commuter and retail arteries in the City of Pittsburgh and provides direct access to downtown Pittsburgh from the neighborhood of East Liberty, Shadyside and Bloomfield. Morewood Ave provides direct access into central Bloomfield and West Penn Hospital and Children’s Hospital complexes

Property Type:

Office

Date on Market:

2020-10-20

Bethlehem Industrial for Lease - Lehigh Valley

o Parking: 2.87/1,000 SF (96 spaces total) o DI Water: RODI System in place o Power: 2,500a/240v Heavy o Backup Generator: Diesel o 2 Air Compressors o 3 Cold Rooms o 1 Dock-High Loading Dock o 13’2” Clear Height

Date on Market:

2024-10-17

Lower Gwynedd Office for Lease - Ft Wash/Spring House

Property Type:

Flex

Date on Market:

2024-10-07

King Of Prussia Office for Lease - King of Prussia/Wayne

Date on Market:

2024-07-16

Pittsburgh Coworking for Lease - Greater Downtown

Inspire any team on Sidney Street Give your brand a boost with flexible office space on Sidney Street. Perfectly placed in the suburbs of South Side Flats, with stunning views across the Monongahela River, Sidney Street provides premium office space just a few minutes from downtown Pittsburgh. Take out an office in an area known for its vibrant nightlife and vintage shopping and expand your network in the heart of the city. You’ll find East Carson St + 24th St Bus Stop just a three-minute walk from the doorstep, and Station Square Subway Station is only 3 mile away. Make a great first impression with professional office space on Sidney Street. Impress potential clients and partners with stylish workspace in a smart, modern building. Help yourself to coffee from our well-equipped kitchen and work quickly with our business-grade WiFi. Get to know potential clients in a pro-business environment and collaborate with talented professionals in our dedicated coworking spaces. Customise your space to suit your unique needs and add logos, brand colors and more. Download the Regus mobile app and manage your space wherever you are in the world.

Property Type:

Office

Date on Market:

2024-07-12

Philadelphia Office, Office/Medical for Lease - University City

Cira Centre, Brandywine Realty Trust’s 29-story flagship skyscraper, graces the west bank of the Schuylkill River and connects Philadelphia’s two primary economic districts: Center City and University City. Designed by Master Architect César Pelli, University City’s first office tower sets a precedence in location as well as architectural design. A signature transit-oriented development, Cira Centre is directly connected to Amtrak’s 30th Street Station – a primary hub for regional, multimodal transportation along America’s Northeast Corridor. At night, the building adds unique excitement to the city’s skyline with 1,500 decorative LED light fixtures programmed to showcase color-dazzling artistic, and community-driven light-shows. Exclusive tenant amenities include a private shuttle, fitness center, and world-class conference facilities. Iron Chef Jose Garces operates a fine dining establishment in the building’s lobby, which also hosts private event functions and wedding celebrations. Cira Centre’s esteemed tenant roster includes Dechert LLP, Essity North America, McKinsey & Company, and BlackRock.

Date on Market:

2025-08-04

Philadelphia Office for Lease - University City

Discover 3025 JFK Boulevard, the 28-story mixed-use West Tower of the iconic and innovative Schuylkill Yards neighborhood. West Tower tenants enjoy elevated work and life experiences within one address. 3025 JFK Boulevard delivers a mix of workspace, life science, retail, luxury residences, and an expansive indoor-outdoor amenity level in Philadelphia's most exciting new neighborhood, Schuylkill Yards. The building's upscale indoor and outdoor amenity spaces on the ninth floor are designed to bring luxury to the heart of University City. 3025 JFK Boulevard will feature a highly anticipated rooftop pool with a sundeck, cabanas, a large-format movie screen and landscaped terrace areas with pergolas, as well as a 14,500-square-foot highly amenitized lifestyle club with a coworking lounge with booths, a kitchenette, and conference and meeting rooms. A state-of-the-art fitness center with locker rooms and showers is also featured. Close to Amtrak's 30th Street Station, Interstate 76, and Interstate 676, 3025 JFK Boulevard offers unparalleled access, whether for pedestrians or by personal vehicle, mass transit, or bike. 3025 JFK Boulevard serves as the central connection point between Center City's economic district and University City's "eds and meds" epicenter, providing immediate connections to vibrant public spaces, lively retail and recreation options, and the region's top talent. Join the bustling Schuylkill neighborhood at the West Tower for a once-and-a-lifetime work and play experience.

Date on Market:

2024-03-04

Pittsburgh Office, Office/Medical for Lease - Greater Downtown

This unique property consists of highly customizable office and research/lab spaces on two floors around a central 2.5 story Atrium. The building was completely renovated in 2002. Both interior and exterior evoke a Contemporary California Industrial aesthetic complete with exposed timber/steel, metal panels, aluminum window walls, exposed brick, hardwood floors, wood plank ceilings with exposed ductwork and abundant daylight throughout. Two balconies provide exterior access. Tenants are also granted access to an off-street parking area with 55 spaces located at the rear of the building. The building is within walking distance to the SouthSide Works and the East Carson Street Business District. Located not far from the Hot Metal Bridge, the totally renovated structure provides easy access to Second Avenue's office properties and Oakland's University/Hospital corridor. The present and future Tenant mix is being reconfigured to accommodate specific adjacencies of Lab/Research (wet lab), Robotics, and Office related space. Floor sizes are up to 12,400 SF for a total of 28,800 GSF. The building design affords Suite sizes of 1,800sf up to and include full floor use. The building's technical infrastructure consists of Lab-rated HVAC systems (HEPA filters) complete with lab humidity control/ pressurized support space, emergency back-up power, a separate feed for 480V power, a 120/208 feed, and lab exhaust and filtration for hoods; air, gas, and vacuum systems. Access is controlled via an Exterior/Interior security with card access entry. There is a passenger elevator and Restrooms on each floor. Rooftop Lab Air-Handlers; Rooftop AHU's for Office and Common Areas; Hot water boiler/steam reheat for Lab Humidity Control. Fully sprinklered; Security monitoring/Fire Alarm with 24/7 remote monitoring. • 24 Hour Access • Security System • Central Heating • Partitioned Offices • Bio-Tech/ Lab Space • Signage • High Ceilings • Secure Storage • Property Manager on Site • Skylights • Natural Light • Air Conditioning

Date on Market:

2025-04-09

Radnor Office for Lease - Upper Main Line

Located in the heart of the prestigious Radnor Corporate Center, this 23,363 RSF sublease opportunity offers a fully built-out, modern workspace tailored for dynamic teams. The suite features 18 private offices, 74 workstations, and a total of 93 seats, complemented by four small and four large conference rooms, two adaptable town hall areas, and a soundproof media studio ideal for content creation or virtual meetings. A dedicated private entrance and prominent exterior signage provide branding visibility rarely available in multi-tenant campuses. Tenants benefit from access to a full-service fitness center, conference center, and multiple outdoor meeting spaces, all managed by an on-site property team. The campus is walkable to over 42 restaurants, 11+ grab-and-go options, 7+ shopping destinations, and 4+ hotels, making it a vibrant and convenient location for employees and visitors alike. Transit connectivity is excellent, with proximity to SEPTA’s Paoli/Thorndale Line, Norristown High Speed Line, and major highways including I-476 and Route 30. Villanova University and the Radnor Trail are nearby, adding to the area’s appeal. Furniture is available upon request, and the space is move-in ready. The sublease runs through February 2028, offering medium-term flexibility for growing companies seeking a premier suburban Philadelphia address.

Date on Market:

2025-10-27

Philadelphia Office/Medical for Lease - University City

Multifamily property with retail spaces on the lower levels. Unparalleled location just steps from UPenn and Drexel campuses and less than one mile from University of the Sciences. Walking distance to/from Penn Presbyterian, Hospital of the University of Pennsylvania(HUP), and Children’s Hospital of Philadelphia (CHOP).

Property Type:

Multifamily

Date on Market:

2023-11-09

Philadelphia Retail for Lease - University City

400,000 SF mixed-use office and lab building with ±20,000 SF ground floor retail space.

Property Type:

Office

Date on Market:

2023-03-21

Philadelphia Office, Retail for Lease - University City

Seated at the heart of Philadelphia’s life sciences community, 3201 Cuthbert is perfectly positioned and equipped to support discovery, collaboration, and innovation in the field, with the most robust life sciences infrastructure in the region.

Date on Market:

2023-03-21

Philadelphia Office for Lease - University City

3711 Market is a premier lab and office building designed to accomodate the needs of today's biotech and life science companies. 3711 Market is conveniently located at the heart of uCity Square, within walking distance of University City's world class Universities, Health Systems, and Research Institutes. 3711 Market is home to fast growing biotech companies, established pharmaceutical companies, and research groups developing the next generation of curative therapies. 3711 Market provides robust lab infrastructure in addition to a 500 Car Parking garage and retail amenities including Han Dynasty and Orange Theory Fitness.

Date on Market:

2023-08-10

Exton Office for Lease - Exton/Whitelands

Glenloch Corporate Center is a three-story, multi-tenant, Class A suburban office building containing approximately 95,800 square feet in the Exton/Whitelands office submarket. The property, built in 1988 and renovated in 2013, is zoned OL (Office Laboratory) and intended for various uses, including business, medical, research, and development. The outdoor area provides an abundance of landscaping, including mature trees, shrubs, three ponds, and an outdoor patio area overlooking the ponds. A loading dock is available for tenant use, and employees can access a common area kitchen with vending services. Glenloch Corporate Center provides superior highway access, with direct access to Route 202 and secondary access provided by Swedesford Road and Route 30. Route 202 is a major limited access regional artery that links King of Prussia, I-76, and I-276 to the east, with West Chester, Exton, Chadds Ford, and Wilmington, Delaware, to the west and southwest. Additionally, the area is serviced by more than five stops on SEPTA's Paoli/Thorndale Line, which provides direct commuter rail access to and from Center City Philadelphia. This convenient connectivity provides easy commutes and access to nearby shopping, restaurants, and industrial parks.

Date on Market:

2024-05-28

Bethlehem Office, Industrial for Lease - Lehigh Valley

• Multiple flex/warehouse/office spaces available • Located in Lehigh Valley Industrial Park (LVIP) VI in Bethlehem Township • Zoned LI/P—Office/Light Industrial • Fully air-conditioned warehouse • Available office suites offer flexible, open floor plan • 3-phase power • All public utilities • Fully sprinklered • Total dock doors: 4 • Total drive-ins: 1 • On-site parking 190 spaces, potential for expansion to 233 spaces • Easily accessible via Routes 33 and 22, as well as I-78

Date on Market:

2024-04-22

Philadelphia Office for Lease - Market Street West

Date on Market:

2022-05-19

Bethlehem Office/Medical for Lease - Lehigh Valley

This two-story, Class A office building offers two prime first floor suite with excellent visibility and accessibility. Recently updated with modern lobby and common area renovations, the building provides a welcoming environment with ample parking for both staff and visitors. Located near residential areas and highways, with strong demographics, it’s home to a dynamic mix of medical and office professionals. Positioned directly off Route 512 with easy access to Routes 22, 33, and 378, the property is both convenient and connected. A generous tenant improvement bonus is available, making this an ideal opportunity for tenants looking to buildout their custom space.This two-story, Class A office building features two prime first-floor suites, offering excellent visibility and accessibility. Recently updated with modern renovations to the lobby and common areas, the building creates a welcoming environment with ample parking for both staff and visitors. It is conveniently located near residential areas and highways, with strong demographics, and is home to a dynamic mix of medical and office professionals. Positioned directly off Route 512, the property provides easy access to Routes 22, 33, and 378, making it both convenient and connected. Additionally, a substantial tenant improvement bonus is available, making this an ideal opportunity for tenants looking to customize their space.

Property Type:

Office

Date on Market:

2025-09-09

Philadelphia Retail for Lease - University City

4101 Market Street is in a QOZ & KOZ. Street Frontages: - 214’ on Market Street - 55’ on 42nd Street - 92’ on 41st Street With an expansive sidewalk/plaza area ranging from 10’ to 20’ on all perimeters of the building. Located in one of Philadelphia’s most thriving neighborhoods, home to a diverse community of college students, artists and families who live and work amid world-class universities, dining, retail and cultural offerings. Pedestrian and biker friendly with access to Market Street bike lane.

Property Type:

Office

Date on Market:

2024-11-21