102 Life Science Properties for Lease in Pennsylvania, USA

Philadelphia Office for Lease - Northeast Philadelphia

Property Type:

Industrial

Date on Market:

2025-11-03

Wayne Flex for Lease - King of Prussia/Wayne

Date on Market:

2025-10-27

Philadelphia Office for Lease - University City

Property Type:

Specialty

Date on Market:

2025-10-23

Lower Gwynedd Flex for Lease - Ft Wash/Spring House

Date on Market:

2025-10-17

Philadelphia Office for Lease - University City

Date on Market:

2025-08-22

Pittsburgh Office for Lease - Parkway East Corridor

• Unique retail opportunity at the forefront of the RIC development and Hazelwood Green neighborhood • 1,400 – 2,000 sf of first-floor retail space • Perfect for café, luncheonette, or boutique eatery • Plenty of natural light • Adjacent to University of Pittsburgh’s Pitt BioForge and the Mill 19 research and development hub • Proximity to the Round House • Future developments include: Lytle Street Apartment Building, Pittsburgh Steelers multi-sport facility, and two acres of outdoor green space for events & community use

Date on Market:

2025-05-14

Bethlehem Industrial for Lease - Lehigh Valley

o Parking: 2.87/1,000 SF (96 spaces total) o DI Water: RODI System in place o Power: 2,500a/240v Heavy o Backup Generator: Diesel o 2 Air Compressors o 3 Cold Rooms o 1 Dock-High Loading Dock o 13’2” Clear Height

Date on Market:

2024-10-17

Lower Gwynedd Office for Lease - Ft Wash/Spring House

Property Type:

Flex

Date on Market:

2024-10-07

King Of Prussia Office for Lease - King of Prussia/Wayne

Date on Market:

2024-07-16

Pittsburgh Coworking for Lease - Greater Downtown

Inspire any team on Sidney Street Give your brand a boost with flexible office space on Sidney Street. Perfectly placed in the suburbs of South Side Flats, with stunning views across the Monongahela River, Sidney Street provides premium office space just a few minutes from downtown Pittsburgh. Take out an office in an area known for its vibrant nightlife and vintage shopping and expand your network in the heart of the city. You’ll find East Carson St + 24th St Bus Stop just a three-minute walk from the doorstep, and Station Square Subway Station is only 3 mile away. Make a great first impression with professional office space on Sidney Street. Impress potential clients and partners with stylish workspace in a smart, modern building. Help yourself to coffee from our well-equipped kitchen and work quickly with our business-grade WiFi. Get to know potential clients in a pro-business environment and collaborate with talented professionals in our dedicated coworking spaces. Customise your space to suit your unique needs and add logos, brand colors and more. Download the Regus mobile app and manage your space wherever you are in the world.

Property Type:

Office

Date on Market:

2024-07-12

Pittsburgh Office, Office/Medical for Lease - Greater Downtown

This unique property consists of highly customizable office and research/lab spaces on two floors around a central 2.5 story Atrium. The building was completely renovated in 2002. Both interior and exterior evoke a Contemporary California Industrial aesthetic complete with exposed timber/steel, metal panels, aluminum window walls, exposed brick, hardwood floors, wood plank ceilings with exposed ductwork and abundant daylight throughout. Two balconies provide exterior access. Tenants are also granted access to an off-street parking area with 55 spaces located at the rear of the building. The building is within walking distance to the SouthSide Works and the East Carson Street Business District. Located not far from the Hot Metal Bridge, the totally renovated structure provides easy access to Second Avenue's office properties and Oakland's University/Hospital corridor. The present and future Tenant mix is being reconfigured to accommodate specific adjacencies of Lab/Research (wet lab), Robotics, and Office related space. Floor sizes are up to 12,400 SF for a total of 28,800 GSF. The building design affords Suite sizes of 1,800sf up to and include full floor use. The building's technical infrastructure consists of Lab-rated HVAC systems (HEPA filters) complete with lab humidity control/ pressurized support space, emergency back-up power, a separate feed for 480V power, a 120/208 feed, and lab exhaust and filtration for hoods; air, gas, and vacuum systems. Access is controlled via an Exterior/Interior security with card access entry. There is a passenger elevator and Restrooms on each floor. Rooftop Lab Air-Handlers; Rooftop AHU's for Office and Common Areas; Hot water boiler/steam reheat for Lab Humidity Control. Fully sprinklered; Security monitoring/Fire Alarm with 24/7 remote monitoring. • 24 Hour Access • Security System • Central Heating • Partitioned Offices • Bio-Tech/ Lab Space • Signage • High Ceilings • Secure Storage • Property Manager on Site • Skylights • Natural Light • Air Conditioning

Date on Market:

2025-04-09

Radnor Office for Lease - Upper Main Line

Located in the heart of the prestigious Radnor Corporate Center, this 23,363 RSF sublease opportunity offers a fully built-out, modern workspace tailored for dynamic teams. The suite features 18 private offices, 74 workstations, and a total of 93 seats, complemented by four small and four large conference rooms, two adaptable town hall areas, and a soundproof media studio ideal for content creation or virtual meetings. A dedicated private entrance and prominent exterior signage provide branding visibility rarely available in multi-tenant campuses. Tenants benefit from access to a full-service fitness center, conference center, and multiple outdoor meeting spaces, all managed by an on-site property team. The campus is walkable to over 42 restaurants, 11+ grab-and-go options, 7+ shopping destinations, and 4+ hotels, making it a vibrant and convenient location for employees and visitors alike. Transit connectivity is excellent, with proximity to SEPTA’s Paoli/Thorndale Line, Norristown High Speed Line, and major highways including I-476 and Route 30. Villanova University and the Radnor Trail are nearby, adding to the area’s appeal. Furniture is available upon request, and the space is move-in ready. The sublease runs through February 2028, offering medium-term flexibility for growing companies seeking a premier suburban Philadelphia address.

Date on Market:

2025-10-27

Philadelphia Office/Medical for Lease - University City

Multifamily property with retail spaces on the lower levels. Unparalleled location just steps from UPenn and Drexel campuses and less than one mile from University of the Sciences. Walking distance to/from Penn Presbyterian, Hospital of the University of Pennsylvania(HUP), and Children’s Hospital of Philadelphia (CHOP).

Property Type:

Multifamily

Date on Market:

2023-11-09

Philadelphia Retail for Lease - University City

400,000 SF mixed-use office and lab building with ±20,000 SF ground floor retail space.

Property Type:

Office

Date on Market:

2023-03-21

Philadelphia Office, Retail for Lease - University City

Seated at the heart of Philadelphia’s life sciences community, 3201 Cuthbert is perfectly positioned and equipped to support discovery, collaboration, and innovation in the field, with the most robust life sciences infrastructure in the region.

Date on Market:

2023-03-21

Philadelphia Office for Lease - University City

3711 Market is a premier lab and office building designed to accomodate the needs of today's biotech and life science companies. 3711 Market is conveniently located at the heart of uCity Square, within walking distance of University City's world class Universities, Health Systems, and Research Institutes. 3711 Market is home to fast growing biotech companies, established pharmaceutical companies, and research groups developing the next generation of curative therapies. 3711 Market provides robust lab infrastructure in addition to a 500 Car Parking garage and retail amenities including Han Dynasty and Orange Theory Fitness.

Date on Market:

2023-08-10

Horsham Township Flex for Lease - Horsham/Willow Grove

This lab incubator offers highly adaptable configurations ranging from 500 to 1,500 square feet, designed to meet the evolving needs of diagnostics and life sciences startups. Each suite is thoughtfully equipped with recessed entry portals, lab-grade flooring, and stainless steel wall protection to support clean and compliant operations. Tenants benefit from ADA-accessible lab sinks, eye wash stations, and designated lab coat hanging areas. Workspaces include 4-foot fume hoods, 30” x 72” lab tables, and integrated casework with chemical storage positioned below the hoods. A dedicated lab support room enhances functionality with lab dishwashers fed by a reverse osmosis water tank, a RO water dispenser, and an ice machine. Labs 5 through 11 are stubbed and pre-configured for future customization in consultation with tenants, ensuring scalability and flexibility as companies grow.

Date on Market:

2023-02-03

Exton Office for Lease - Exton/Whitelands

Glenloch Corporate Center is a three-story Class A office building in the Exton/Whitelands submarket with 1,432 SF- 15,000 SF of available space for lease. Zoned OL for business, medical, and R&D uses, it features mature landscaping, three ponds, an outdoor patio, a loading dock, and a shared kitchen. The property offers direct access to Route 202, with additional connectivity via Route 30, Swedesford Road, and multiple SEPTA Paoli/Thorndale Line stops, providing convenient commutes and proximity to retail, dining, and nearby business hubs.

Date on Market:

2024-05-28

Bethlehem Office, Industrial for Lease - Lehigh Valley

• Multiple flex/warehouse/office spaces available • Located in Lehigh Valley Industrial Park (LVIP) VI in Bethlehem Township • Zoned LI/P—Office/Light Industrial • Fully air-conditioned warehouse • Available office suites offer flexible, open floor plan • 3-phase power • All public utilities • Fully sprinklered • Total dock doors: 4 • Total drive-ins: 1 • On-site parking 190 spaces, potential for expansion to 233 spaces • Easily accessible via Routes 33 and 22, as well as I-78

Date on Market:

2024-04-22

Philadelphia Office for Lease - Market Street West

Positioned at the epicenter of Philadelphia’s thriving bioscience corridor, 2300 Market Street delivers a next-generation research environment designed to accelerate discovery. This 225,000 SF life science hub combines state-of-the-art infrastructure with a premier Center City address, offering unmatched connectivity to University City’s academic institutions and the vibrant Market Street lifestyle. The building’s flexible lab-to-office ratio, soaring ceilings, and robust mechanical systems create an adaptable platform for cutting-edge R&D. Tenants will enjoy private terraces, a serviced café and lounge, fitness amenities, and secure bicycle storage—all complemented by onsite and adjacent parking. With LEED Gold and Fitwel certifications, 2300 Market sets a new benchmark for sustainability and wellness in life science real estate. Steps from Rittenhouse Square and 30th Street Station, this location provides seamless access to regional and national transit, while surrounding retail and dining options foster collaboration and convenience.

Date on Market:

2025-12-11

Bethlehem Office/Medical for Lease - Lehigh Valley

This two-story, Class A office building offers multiple suites including two prime first floor suite with excellent visibility and accessibility. Recently updated with modern lobby and common area renovations, the building provides a welcoming environment with ample parking for both staff and visitors. Located near residential areas and highways, with strong demographics, it’s home to a dynamic mix of medical and office professionals. Positioned directly off Route 512 with easy access to Routes 22, 33, and 378, the property is both convenient and connected. A generous tenant improvement bonus is available, making this an ideal opportunity for tenants looking to buildout their custom space.

Property Type:

Office

Date on Market:

2026-04-27

Philadelphia Retail for Lease - University City

4101 Market Street is in a QOZ & KOZ. Street Frontages: - 214’ on Market Street - 55’ on 42nd Street - 92’ on 41st Street With an expansive sidewalk/plaza area ranging from 10’ to 20’ on all perimeters of the building. Located in one of Philadelphia’s most thriving neighborhoods, home to a diverse community of college students, artists and families who live and work amid world-class universities, dining, retail and cultural offerings. Pedestrian and biker friendly with access to Market Street bike lane.

Property Type:

Office

Date on Market:

2024-11-21

Wayne Flex for Lease - King of Prussia/Wayne

INQ 400 is a single story 138,065 SF building located in Wayne, PA within close proximity to major life science hubs. Zoned to meet the needs of all aspects of life sciences, the building was originally constructed in 1969 and is under redevelopment to specifically meet the needs of “speed to market”. After extensive review with expert architects, it was found that a majority of the building’s existing infrastructure lends itself perfectly to both cGMP and R+D. This includes DX HVAC roof top units, 34 KV primary electrical service, gas, water, sanitary and fire protection. There is also a 500 KW diesel emergency generator on the property. The 20’-24’ ceiling heights throughout the building provides companies with the flexibility to add additional mezzanine, making it ideal for manufacturing. Ample interior loading docks throughout the building are also in place for ease of inbound and outbound materials. Additional enhancements underway include a new façade, installation of a 6 inch water line and the addition of a rooftop chiller.

Date on Market:

2021-07-26

Trevose Industrial for Lease - Lower Bucks County

Located in the Metropolitan Business Center, this 118,000-square-foot industrial distribution property is convenient to Route 1, PA Turnpike & Interstate 95.

Date on Market:

2025-11-21