63 Life Science Properties for Lease in Pennsylvania, USA

Horsham Township Flex for Lease - Horsham/Willow Grove

• Recently renovated GMP/R&D building • Located in the Keystone Innovation Zone (KIZ). • No gross receipts tax in Horsham Township • Building features include: 1. Power: (2) 2000AMP, 480/277, 3 phase services 2. (5) New loading docks 3. New 4” Domestic water service entering building 4. New gas service to building with sufficient capacity for typical lab tenant—will support 100% OA heating 5. 18’6” clear height 6. Interior demo

Date on Market:

2018-08-30

Pittsburgh Office for Lease - Oakland

The Riviera is the ideal location for your wet lab, biotech, and office space, situated in the heart of Pittsburgh’s Technology Center, just a quick 5-minute commute from Downtown. Overlooking the riverfront with views of Downtown and the Southside Marina, the property features an on-site fitness center, loaner bicycles, a DeFer Coffee and Tea shop, a conference center, outdoor patios and eating areas, and weekly BioBreakfast networking events for life sciences. The building benefits from abundant natural light and offers flexible first-generation space that you can customize to meet your needs. The Riviera also provides convenient accessibility with connections to I-376, bus lines, and dedicated university shuttles that link you to Oakland’s top talent. Additionally, the Pittsburgh Technology Center (PTC) includes multiple parking garages and connects to the Three Rivers Heritage Trail for biking and walking options.

Date on Market:

2025-12-18

Philadelphia Office for Lease - University City

3535 Market Street is an 18-story, Class-A office/Medical building located in downtown Philadelphia. It has terrific views of the city, continuous glass lines, large floor plates, and easy access to public transportation. Prominent location in the heart of the University City Science Center with proximity to the University of Pennsylvania, Drexel University, and Children's Hospital of Philadelphia

Date on Market:

2025-01-31

Philadelphia Office for Lease - University City

3624 Market Street is a five story lab office building centrally located in the heart of uCity Square. The building has GMP, R&D laboratory space and office space. uCity Square is rich in amenities. uCity Square tenants benefit from a vibrant tech, medical device and life science ecosystem adjacent to major academic and research institutions including the University of Pennsylvania, Drexel University, Penn Medicine, the Children’s Hospital of Philadelphia, Wistar Institute and Monel Chemical Senses Center. 3624 is located in a Keystone Innovation Zone.

Date on Market:

2025-03-13

Philadelphia Office for Lease - University City

One uCity Square is a premier Class A lab and office tower rising 13 stories in the heart of Philadelphia’s University City, a nationally recognized innovation district. Delivered in Q3 2022, this ±400,000 SF trophy asset is part of the transformative 7.7 million SF uCity Square mixed-use development, which integrates life sciences, academic institutions, and entrepreneurial energy into a walkable, transit-rich ecosystem. Tenants will benefit from a dynamic work environment designed to attract top-tier talent. The building features 15-foot slab-to-slab heights, 32K SF floor plates, private outdoor terraces, and panoramic views of Center City and Fairmount Park. It is the only building in Philadelphia to offer 100% outside air, bipolar ionization in common areas, and MERV 14 filtration—delivering air quality nearly double that of typical commercial buildings. One uCity Square is located within both a Keystone Opportunity Zone and a Federal Opportunity Zone, and qualifies for a 10-year real estate tax abatement, offering substantial financial advantages. The site is adjacent to institutions such as Penn Medicine, Drexel University, and CHOP, and is served by multiple transit options including Amtrak, regional rail, subway, and trolleys. The surrounding uCity Square community includes ground-floor retail, activated plazas, and curated programming such as Venture Café events and outdoor wellness activities. Tenants also enjoy hospitality-inspired lobbies, structured parking, indoor bike storage, and contactless entry from street to suite.

Date on Market:

2025-09-29

Philadelphia Coworking for Lease - University City

Enviable connectivity with a riverside location, this landmark location in University City is ideal for businesses that want to make this city their own. The CIRA Center Office Space has a direct connection to Amtrak’s 30th Street Station, so it’s convenient for commuters and business travel. This striking building with a strong presence in Philadelphia’s skyline offers a rooftop park - the perfect place to relax and make plans between meetings. Step outside to explore downtown Philadelphia or take in the views of the Schuylkill River.

Property Type:

Office

Date on Market:

2023-06-15

Newtown Coworking for Lease - Lower Bucks County

The Silver Lake Executive Campus consists of 35 acres and has a site capacity for 325,000 square feet of exceptional quality mid-rise office space.* Less than 1 mile from the Newtown/Yardley interchange of I-95 in Newtown Township, Bucks County.* Extensive frontage on, and direct access to, the Newtown Bypass (Rt 413).* Build-to-suit sites available. Silver Lake Rd & Rt 332

Property Type:

Office

Date on Market:

2007-04-18

Exton Office/Medical for Lease - Exton/Whitelands

Eagleview is a live work play community, consisting of 800 acres, located on Route 100 at the Downingtown Interchange (Exit 312) of the PA Turnpike. Eagleview provides the highest quality office, R & D, manufacturing, retail and residential accommodations to over 10,000 people. 665 Stockton is located one block from Eagleview Town Center amenities; On-site amenities: The Brickside Grille, Suburban Beer Garden, Al Pastor Mexican Restaurant, Bluefin Sushi, Gemini Hair Design & Spa, Wellington Square Book Shop, Persis Indian Grill, Rita's Water Ice, Good Life Organic Kitchen, Twin Valley Coffee, Good Girls Bakery and acac Fitness Center are located at the Town Center. Ideally situated on Route 100 at the Downingtown Interchange (Exit 312) of the PA Turnpike.

Property Type:

Office

Date on Market:

2019-07-02

Oakmont Flex for Lease - Parkway East Corridor

Build to suit in an established business park. Flex space proposed that would include office and warehouse. Build to suit opportunity.SIZE OF BUILDING: 37,000 SQUARE FEETAVAILABLE SPACE: 21,789 SQUARE FEETOFFICE AREA: 8,842 SQUARE FEETLAB AREA: 3,867 SQUARE FEETWAREHOUSE AREA: 9,080 SQUARE FEETOFFICE AREA:FOUR PRIVATE OFFICES, CONFERENCE ROOM, KITCHEN AREA, LARGE BULLPEN AREAWAREHOUSE AREATWO LOADING DOCKS - 12 DOORSCEILING HEIGHT: 14MENS/LADIES RESTROOMS AND SHOWERLAND AREA: 7.47 ACRESLEASE RATE: OFFICE: $12.50 PSFWAREHOUSE: $6.50 PSF + ALL UTILITIES, AND JANITORIAL LOCATED IN THE HEART OF BEAUTIFUL OAKMONT BUSINESSDISTRICT & MINUTES FROM PA TURNPIKE AND ROUTE 28 Located in the heart of beautiful Oakmont Business District and minutes from the Pa. Turnpike and Route 28

Date on Market:

2022-01-24

Horsham Township Office for Lease - Horsham/Willow Grove

Babylon Business Campus, home to 955 Horsham Road, offers 16 single story multi purpose buildings and a three-story office tower. It was designed with flexibility in mind, ensuring the complex can meet the needs of any business with an abundance of natural lighting and flexible floorplans. It is ideally suited for research and development facilities, high tech manufacturing, distribution and corporate offices. 955 Horsham offers abundant onsite parking for tenant and client use as well as a restaurant to make lunches during the week simple. In addition to nearby national and local retailers, Squires Golf Club, Talamore Country Club and Old York Road Country club are a short drive away. The proximity to the I-611 and the Fort Washington Expressway make commuting to and from the office a breeze. The complex is nestled in the suburbs of Philadelphia in Horsham, Montgomery County near several parks including Carpenter Park, Deep Meadow Park, and Kohler Park.

Date on Market:

2026-01-22

Spring Mills Office for Lease

Date on Market:

2026-05-07

Philadelphia Office for Lease - Navy Yard

4751 League Island Blvd presents a rare sublease opportunity within Philadelphia’s thriving Navy Yard innovation district. Purpose-built for biotech and advanced therapeutics, this facility offers up to 82,000 SF of flexible space, including ISO-7 and ISO-8 cleanrooms, support labs, cold storage, and warehousing. The building is engineered for speed-to-market and operational efficiency, with robust utility infrastructure including compressed air, CO2, N2, and backup power systems. Tenants benefit from seamless integration of office, R&D, and manufacturing areas, with options for dedicated entrances and future expansion. The site is part of a 400,000 SF manufacturing campus adjacent to CDMO and testing services, supporting the full lifecycle of life science operations. Located just minutes from Philadelphia International Airport, University City, and Center City, the Navy Yard offers unmatched accessibility and lifestyle amenities. With over 20 acres of parks, waterfront trails, and on-site dining, this vibrant ecosystem attracts top talent and fosters innovation. The sublease runs through 2037, providing long-term stability in a premier location.

Property Type:

Flex

Date on Market:

2025-10-23

Philadelphia Office for Lease - University City

Pennovation Center is an innovation hub with a variety of premium shared or private space options for innovators and researchers around the Tri-State area. Pennovation Center fosters a sense of community and encourages collaborative endeavors within the Pennovation Works, and regional innovation, ecosystem

Date on Market:

2024-02-20

State College Office for Lease

Date on Market:

2025-02-26

Pittsburgh Office, Industrial for Lease - Greater Downtown

River Avenue Distribution and Technology District is a transformative project aiming to revitalize the historically significant former H.J. Heinz into a modern, functional warehouse. This multi-phase development offers two fully renovated modern Class A warehouse and flex buildings —Building 7 and Building 8 — along with research and development space positioned along the scenic Allegheny River. Buildings 7 and 8 represent the first chapter in a project that continues to build relevance to the Northern Pittsburgh area. Ideal users include last-mile distribution, flex/tech users, value- add manufacturing, biotech, autonomous development and research, and more. Phase I of the River Avenue Distribution and Technology District offers a total of 300,000 square feet of Class A warehouse with a minimum divisibility of 10,000 square feet and a maximum of 200,000 square feet and includes a contiguous internal 600-vehicle parking garage. Building 7 is a 141,615-square-foot property, subdividable to 50,000 square feet, featuring a 25-foot clear ceiling height, one drive-in door, 10 dock doors featuring overhead doors with dock shelters, dock lights, 60,000-pound mechanical levels, and additional dock potential. Building 8 is a 141,460-square-foot property featuring a 29-foot clear ceiling height and seven dock doors with dock shelters, dock lights and 60,000-pound mechanical levels. Both buildings have all-new LED lighting and ESFR 4-zone service. AFP- 1010 intelligent fire detection control system with combo audio visual, signal and strobe lights fire protection system. An on-site parking garage accommodates 600 vehicles and potential tractor-trailer staging. Phase 2 will feature state-of-the-art flex/research and development space with unparalleled views of the Allegheny River and the constantly evolving Strip District. River Avenue Distribution and Technology District is an in-fill location providing exceptional accessibility and proximity to major thoroughfares and area amenities. Ideally located along the Allegheny River, this project thrives in an advantageous location with quick and convenient access to Pittsburgh's Central Business District, public transportation, and rail service. Within a five-minute drive is unmatched access to the Strip District (Robotics Row), Lawrenceville, Downtown Pittsburgh, and primary transportation arteries such as Interstates 279 and 579, as well as Route 28. When high-end work environments, connectivity, and convenience are key, River Avenue Distribution and Technology District is the ideal destination.

Date on Market:

2025-06-26