54 Life Science Properties for Lease in Santa Clara County, USA

Milpitas Flex for Lease

Situated in Milpitas, 688 Gibraltar Court is a research and development manufacturing building that has recently undergone extensive renovations, ensuring a modern and efficient workspace for businesses. With a substantial 2,000-amp 277/480-volt power panel, it offers robust electrical support for manufacturing and research needs. The presence of a backup generator ensures uninterrupted operations even during power outages. Furthermore, the building features a convenient double-door platform and a grade-level door, facilitating easy access and efficient logistics. In the bustling industrial hub of Milpitas, 688 Gibraltar Court boasts excellent connectivity via easy access to Highway 237, Interstate 680, Interstate 880, and Calaveras Boulevard. The property is conveniently located within walking distance of the new BART Milpitas Station, ensuring a seamless commute for administrative staff. Nearby amenities, including Big O Tires, Chick-fil-A, Safeway, Panda Express, McDonald's, and Starbucks, offer a variety of dining and service options for those passing through. This strategic industrial location can reach a population of approximately 8.5 million people in major cities like San Jose, San Francisco, Fresno, Los Angeles, San Diego, and Las Vegas, all within a day's drive. With its modern upgrades, powerful infrastructure, and exceptional location near major transit routes and amenities, 688 Gibraltar Court stands out as a premier choice for businesses seeking a versatile and accessible R&D and manufacturing facility in Milpitas.

Date on Market:

2025-11-06

Milpitas Flex for Lease

Welcome to 1561 Buckeye Drive, a versatile commercial opportunity for businesses seeking a well-equipped facility for research and development (R&D), manufacturing, or light industrial operations. The 44,815-square-foot building spans a generous floor plan with expansive lab spaces designed for innovation and productivity. 1561 Buckeye Drive has a long list of key features that boost efficiency. This advantageous property boasts large, open-concept lab spaces, perfect for a variety of research and development activities. With ample room for workstations, equipment, and specialized setups, this space offers the flexibility needed for cutting-edge projects. The facility's strategically positioned roll-up doors provide easy access for deliveries and shipments, while multiple loading docks ensure smooth logistics operations. The property has modern amenities, including 16-foot, 8-inch ceilings and 2,000-amp, 120/480-volt, 3-phase heavy power. Finally, this site is zoned to accommodate a wide range of industrial and commercial uses. Strategically situated in the heart of Milpitas, California, 1561 Buckeye Drive benefits from its proximity to major highways, including Interstate 880, offering seamless access to Silicon Valley, transportation hubs, and the greater Bay Area. Whether a business is developing new technology, expanding operations, or creating custom products, 1561 Buckeye Drive provides the flexibility to meet needs.

Date on Market:

2025-01-08

San Jose Office for Lease - South San Jose

Located at 6399 San Ignacio Avenue in San Jose, California, this premium Class A top-floor office space offers a rare opportunity to lease in one of Silicon Valley’s most sought-after commercial corridors. The property features a modern two-story office building totaling 41,831 square feet situated on a spacious ±2.5-acre site. Recently renovated in 2023, the building showcases a sleek design with huge windows that allow natural light to flow through, a welcoming lobby, and energy-efficient LED lighting. 6399 San Ignacio Avenue is fully occupied except for this available second-floor suite. The first floor is leased to a premier hospital medical office tenant undergoing new buildouts scheduled for April 2026. The second floor is home to a semiconductor design company, a marketing agency, and a software firm, creating a professional environment. Tenants will enjoy ample on-site parking with 134 ADA-compliant surface spaces, suite door signage, and lobby directory signage for enhanced visibility. Strategically positioned at the corner of San Ignacio and Santa Teresa, the property offers excellent accessibility. Located one block from the Light Rail station, you’ll enjoy easy access to Highways 85 and 101, creating a reverse commute. The building is approximately 15 minutes from Norman Y. Mineta San Jose International Airport, offering regional and national connectivity. The surrounding area is affluent, with a median home value of $1,044,483, and boasts a highly educated population: 44% of residents within a 10-mile radius hold a college degree. San Jose continues to be a powerhouse in the tech industry, attracting top talent and investment. The city leads the nation in GDP growth, averaging 8.3% annually over the past decade, and remains a hub for venture capital and innovation, particularly in artificial intelligence. With proximity to multiple medical centers and a thriving business ecosystem, this office space provides an ideal setting for companies seeking a prestigious address in Silicon Valley and an employee-friendly reverse commute, enabling a work-life balance.

Date on Market:

2025-10-09

Mountain View Flex for Lease

1070-1080 Terra Bella Avenue offers growing businesses a Class A, freestanding flex facility for immediate occupancy with a prime location in Mountain View, California. Boasting recently renovated interiors and desirable features and specs, this presents a premier leasing opportunity for a wide range of uses such as light industrial, technology, medical labs, research and development, and more. This versatile facility delivers 14,948 square feet of modernized space, with a mix of office, lab, and warehouse space across two floors. The building is equipped with 100% HVAC coverage, fire sprinklers, and a heavy 3-phase power supply (1,000 amps, 277/480 volt), supporting a range of intensive uses. It also includes robust loading infrastructure, with five grade-level doors and an 18-foot interior clear height. Operational flexibility is enhanced by portioned office space, conferencing facilities, accessible restrooms, and two studios with kitchens and showers. Recent upgrades to the interiors include quality finishes, with large windows, built-in cabinetry, glass accents, and premium carpet flooring in the office spaces, providing a clean, bright, and energizing work environment. Situated with immediate access to Highway 101, 1070-1080 Terra Bella Avenue provides swift connections across the Greater Bay Area, reaching San Jose in just 20 minutes and San Francisco in under an hour. The location also offers convenient public transit options, with the Caltrain Shuttle reachable in only a two-minute walk. Longer-distance transportation is also readily available at San Jose Mineta International Airport, just 9.7 miles away. Mountain View presents a compelling destination for growing businesses, home to major presences or headquarters for Fortune 100 companies like Alphabet, Google, Microsoft, and more. The area is brimming with talent, fueled in part by nearby Stanford University, with over 71% of the growing population of more than 142,000 living within 3 miles of the property holding a bachelor’s degree or higher, and average household incomes sitting above $192,000. This highly educated workforce ensures easy access to top-tier talent, fueling future growth and expansion for tenants at the subject property. Don’t miss out on this incredible opportunity. Contact the JLL team today to set up a tour and learn about all the advantages of choosing 1070-1080 Terra Bella Avenue.

Date on Market:

2025-04-21

Milpitas Office for Lease

McCarthy Center is Silicon Valley’s best value–a newly refreshed campus with modern design, engaging amenities and flexible solutions for companies of all sizes. From move-in ready suites with flexible lease terms to full floors and buildings, a range of options in the 1.1 million SF, 19-building campus accommodate growing companies with office, R&D and lab space. Attract and retain top talent with a full suite of amenities and modern design, including bold entries and highly-visible signage. Take your workday outdoors for fresh air and inspiration in the 10+ outdoor workspaces ideal for connection and collaboration. Host company events, networking and happy hours in the event-ready conferencing space. Energize your day with craft coffee and fresh, made-to-order dishes from The Eatery. Position your business for success and put more of what matters within reach thanks to a convenient Silicon Valley location near Hwy 237 and I-880, resort-style living at North Park, and dining, retail and entertainment at McCarthy Ranch Marketplace.

Date on Market:

2026-05-07

San Jose Flex for Lease - North San Jose

Charcot Industrial Park offers more than 164,000 square feet of quality commercial real estate space across four buildings and 19 suites in the heart of California’s Silicon Valley. Well-suited for a wide range of light industrial uses, this park offers flexible configurations of R&D, manufacturing, and warehouse space. Buildings within the industrial park feature 18-foot clear heights, convenient grade-level loading, and a desirable 2.83:1,000-square-foot parking ratio, providing functionality and efficiency for a variety of business operations. This North San Jose property is directly adjacent to an on-site deli and picnic courtyard, providing tenants with convenient amenities right at their doorstep. The surrounding area offers easy access to numerous restaurants and retail options, enhancing the overall tenant experience. The park also benefits from excellent visibility, with frontage along Interstate 880, providing swift connectivity to Highway 101, State Route 87, the Montague Expressway, and East Brokaw Road. Positioned in an attractive Silicon Valley location, the property is near prominent businesses, including PayPal Corporate Headquarters, TSMC Technology Inc., Restaurant Depot, the American Red Cross, Tesla Energy Testing Center, and Mercedes-Benz Research & Development. Charcot Industrial Park delivers exceptional commercial space, superior amenities, excellent connectivity, and an ideal Silicon Valley location, making it an ideal choice for businesses seeking quality and convenience.

Date on Market:

2025-06-24

Sunnyvale Office/Medical, Flex for Lease - Moffett Park

-Unit 2: 2,000± SF -Asking Rent: $3.50 PSF Gross -Existing eye wash station -Existing hood for chemical use -Multiple sinks -Chemical proof countertops -Comes with two private offices -Unit 1: 900± SF -Asking Rent: $3.50 PSF Gross -Plenty of cabinet space for lab equipment & chemical storage. -Two sinks. -Exhaust duct hookup available if needed. -Shared common area bathrooms. -Shared common area breakroom with fridge, sink & microwave. -Reception desk at entrance of building along with mail area. -24-hour security for this property. -Located near HWY 101 & 237.

Date on Market:

2026-04-13

Sunnyvale Office/Medical for Lease

Date on Market:

2026-01-20

Sunnyvale Industrial for Lease

Nestled in the dynamic and innovation-driven city of Sunnyvale, 388 Oakmead Parkway offers an exceptional opportunity for businesses looking to thrive in one of the most sought-after locations in the Bay Area. With convenient access to major tech campuses, highways, and public transit, this property combines modern functionality with strategic positioning. Dedicated Lab with 10 Racks • Can operate 10 H200 GPUs, Management Nodes & Petabyte Storage Clusters • 1 megawatt of power to building • Enough power available to expand to a full B200/B300 GPU Cluster • Each rack includes two 208V 3 phase 48A PDUs

Date on Market:

2026-01-15

San Jose Flex for Lease - South San Jose

6872 Santa Teresa Boulevard offers ±3,447 square feet of high-identity R&D flex space available for Sublease in San Jose, California. This modern facility features an impressive glass line, abundant natural light, and a professional image along Santa Teresa Boulevard. The office area boasts 10-foot ceilings and 9-foot doors with 2-foot sidelights, creating an open and inviting workspace. The manufacturing area is equipped with HVAC, VCT flooring, skylights, and painted walls, supporting a variety of business operations. With 200 amps at 120/208 volt, 3-phase power, and a grade-level loading door, the property is well-suited for flexible R&D, light manufacturing, or tech uses. The site is conveniently located near major thoroughfares, amenities, and public transportation, making it an ideal choice for businesses seeking a strategic Silicon Valley address.

Date on Market:

2025-12-05

Mountain View Flex for Lease

• Renovated Flex/R&D Building • Secure Parking Lot/Yard • 3.3/1,000 Parking • Unparalleled Freeway Access (HWY 101) • $1M Seismic Retrofit Upgrade - Level 3 Rating - Meets the standards of Silicon Valley’s prominent technology companies • Restroom: Two (2) ADA Cores, One including a M & F shower •Renovations: New main Sewer Line 2023. Exterior Paint, Fresh Seal/Slurry, ADA remodel, R&D Loading Doors, Polished Concrete.

Date on Market:

2025-10-29

San Jose Office for Lease - West San Jose

Welcome to 560 S Winchester Blvd, a premier Class A office building located in the heart of West San Jose, adjacent to the vibrant Santana Row. This six-story, 100,841 SF property offers a sophisticated and modern workspace with exceptional amenities and unbeatable access. Built in 2000 and LEED Gold certified, the building blends high-end finishes with sustainable design, making it ideal for forward-thinking businesses. With flexible leasing options including a 9,410 SF direct lease and a 17,132 SF plug-and-play sublease, tenants can enjoy a move-in-ready environment complete with high-end furnishings, conference rooms, labs, and wellness spaces.

Date on Market:

2025-10-28

Sunnyvale Office/Medical for Lease

o Easy access to HWY 101, 85, 82, 280, 880 & 237. o Ample Parking On site o Located near numerous Fortune 500 high tech companies o Suite 1: 2,694± SF o $2.50 PSF Modified Gross o Front desk receptionist area o Two bathrooms o 5 private offices o Common area for office cubicles o Conference room with white board o Storage closet o Break room/kitchen with table

Property Type:

Flex

Date on Market:

2026-05-14

Mountain View Flex for Lease

• Multiple office & lab areas • Conference rooms • Kitchen • Wet lab • Two clean rooms • Fume hood • DI water system • 4:1000 Parking • Glass Roll Up Door, Shipping & Receiving Area • Easy Access to 101

Date on Market:

2023-09-25

San Jose Office for Lease - North San Jose

Metro Plaza is a three building, Class A office project located in North San Jose. Adjacent to Highways 87 and 101 with easy access to Interstates 280, 680, and 17/880. There is a convenient VTA Light Rail and bus stop adjacent to the Project. The Project is approximately two miles north of downtown San Jose. The Project features a common conference center, fitness center and secured bike storage/repair lab.

Date on Market:

2026-02-18

Mountain View Flex for Lease

Great Flex building in desirable Mountain View. Many building upgrades / Exterior and Interior! Offering $1.00 PSFT Bonus to procuring broker.

Date on Market:

2026-01-23

Sunnyvale Office for Lease

Date on Market:

2025-07-25

Sunnyvale Office for Lease

Close Proximity to Downtown Sunnyvale. Great Access to Hwys 101, 85 & 237. Expansion Opportunity within Project

Property Type:

Industrial

Date on Market:

2026-01-23

Milpitas Flex for Lease

720-740 S Milpitas Blvd is a multi-tenant flex building with excellent Access to Hwy 680, 880 and 237. The property sits close to numerous amenities and Milpitas BART Station. There is ample parking onsite (3.8/1000 parking available).

Date on Market:

2024-09-03

Sunnyvale Flex for Lease

The property at 680 W Maude Avenue in Sunnyvale is a free standing office and R&D building totaling approximately 39,311 square feet with high end plug and play interiors. The space features existing labs equipped with nitrogen, CDA, a vacuum pump and a gas monitoring system, along with an expansive break room, training areas and a large private outdoor amenity space. Additional on site amenities include a fully outfitted gym with showers and lockers, bike lockers, a dual EV charging station and grade level loading. With ample parking at a ratio of four per one thousand square feet and two thousand amps of power, the building is designed to support a wide variety of operational needs. Its location offers walking distance access to the Sunnyvale Caltrain Station and a deep selection of nearby dining and service amenities. Available for Sale or Lease.

Date on Market:

2024-08-26

San Jose Office, Flex for Lease - South San Jose

302 Enzo Drive in San Jose offers flexible Office, R&D, and Life Science space for lease, ranging from approximately 3,872 to 23,359 square feet. This modern building features prominent signage with freeway visibility, a renovated lobby, and a variety of suite configurations to suit different business needs. Tenants benefit from robust infrastructure, including high power capacity, dock and grade loading, and a private freight elevator. The property’s location provides easy access to major amenities, parks, and trails, making it an ideal choice for companies seeking a dynamic and accessible workspace in Silicon Valley.

Date on Market:

2025-07-11

San Jose Flex for Lease - San Jose-Berryessa

R&D condos.

Date on Market:

2024-05-16

Milpitas Flex for Lease

Date on Market:

2024-06-17

San Jose Flex for Lease - North San Jose

Walking distance to light rail, retail amenties & lodging

Date on Market:

2024-05-01