457 Life Science Properties for Lease in California, USA

Los Angeles Office/Medical for Lease - Inglewood/South LA

The Luzzatto Company began construction on "The Depot" in May 2021 with a completion date of 4Q 2022. The Depot is a ground up, Class A, transit-adjacent, architecturally significant, environmentally-conscious, creative office project with over 17k feet of landscaped outdoor patios and decks, two levels of secured subterranean parking, and 15' clear ceilings. The Depot is built with steel, concrete, wood and glass. Located only 2 blocks from the intersecting MTA stops of the blue line running along Exposition from downtown to the beach, and the new LAX line running along Crenshaw, from LAX/Inglewood to this location, The Depot may be the most transit-friendly development in the entire city. With 360 degree views of Los Angeles through towering palm trees, the historic West Adams location is unique, vibrant, and classic Los Angeles.

Property Type:

Office

Date on Market:

2020-12-02

Santa Ana Office/Medical, Medical for Lease - Main Place Area

Medical & Professional Campus, with easy FWYS 5, 22, 55, 57 access, Surface Parking with Ratio of 6 per 1,000. On site Medical Lab, State of the Art Medical Imaging &Radiology and Pharmacy, State of art Tenant Improvement available for qualified tenant. Visible from the 5 Freeway and Immediate Access to 3 Major Southern California Freeways, 5, 22, 55 and close proximity to 57, Located next to the Hard Corner of 17th Street and Grand Avenue with the car count of approximately 80,000 cars per day.

Date on Market:

2025-04-16

South San Francisco Flex for Lease

Kilroy Oyster Point Phase 2 is now delivering: three state-of-the-art buildings totaling approximately 865,000 square feet in the heart of South San Francisco—the birthplace of biotechnology. Kilroy Oyster Point Phase 2 is a premier waterfront life sciences environment designed to accelerate scientific innovation within one of the Bay Area’s most established biotech clusters. Set along Oyster Point’s shoreline, the campus blends purpose-built lab and office buildings with expansive outdoor zones, providing an energized setting that supports collaboration, wellness, and productivity. Tenants benefit from next-generation infrastructure including significant floor load capacities, large open floor plates, and LEED Gold–targeted design, all arranged within an interconnected outdoor village featuring amphitheater seating, a conference center, fitness amenities, and Farewinds restaurant and café. The location offers both inspiration and convenience, just steps from beaches, trails, hotels, and immediate access to ferry service and major freeways, making Phase 2 a destination for companies seeking an elevated, amenity-driven research workplace.

Date on Market:

2025-12-04

Los Angeles Office for Lease - Olympic Corridor

The Olympic Corridor sits at the center of Los Angeles’ Westside. Adjacent to the Interstates 10 and 405, the area has some of the best transportation access in Greater Los Angeles. The opening of the Expo Line expansion from Culver City to Santa Monica in 2016 was a big win for the Olympic Corridor, making it possible for workers to travel on the line to points between Santa Monica and Downtown. Retail options are strong in the Olympic Corridor, with a plethora of dining and shopping options. The Sawtelle Corridor, also known as Little Osaka, has become one of the hotspots for restaurants on the Westside.

Date on Market:

2023-12-11

Redwood City Flex for Lease - Foster City/Redwood Shrs

Bayshore Technology Park. 3800 Bridge Parkway, Redwood Shores, CA.

Date on Market:

2026-03-09

Mountain View Office, Flex for Lease

701 E Middlefield Road is a leasing opportunity for businesses looking for a moldable office flex building with options to occupy the full building or divide the spaces. The available office spaces are currently built with spacious floor plans and room for over 80 private offices, a conferencing facility, and many bullpen spaces allowing for cubicles, reception, and waiting areas. This two-story, 56,000-square-foot property was primarily built in 1997 for uses in research and development. A small amount of biotech or lab space is included at 701 E Middlefield Road, where tenants can expect specifications including deck-to-deck height of 18 feet on the first floor and 16 feet on the second floor, plus 2,000-amp, 277/480-volt, 3-phase power. Nestled within the Mountain View Research Park, this flex property is adjacent to notable companies such as LinkedIn Corporation, Lunar Energy, Honda Innovations, Panasonic, Apple, and SETI Institute. Tenants will benefit from easy access to Highways 101, 280, 237, and 85 within a three-mile radius. Take advantage of exceptional visibility and a sought-after destination in Mountain View at 701 E Middlefield Road.

Date on Market:

2020-07-24

Alameda Flex, Industrial for Lease

• Central Bay Area location close to San Francisco, the Peninsula, Oakland International airport, Port of Oakland and universities • Functional footprint, heavy power and loading • Secure building site within a well-maintained business park • Superior modern construction meeting all codes • High-visibility building to display to customers and employees • Low business taxes • Excellent freeway access and transportation options, including I-880, the Harbor Bay ferry to San Francisco, and a business park shuttle to the ferry and Coliseum BART station, which is free to end users

Date on Market:

2026-02-18

San Mateo Flex for Lease

Genesis 1900 Alameda de las Pulgas offers ±113,000 SF of Class A life science research space. The proximity to Stanford and South San Francisco creates unparalleled access to the world’s leading innovation clusters. Located in the center of the peninsula, the project connects directly to San Jose, East Bay and San Francisco which enables growing companies to attract and retain talent from across the Bay Area’s research institutions (Stanford, UCSF, and Berkeley). The floor plates offer a variety of small to mid-size suites and solutions for life science companies.

Date on Market:

2025-11-06

Redwood City Office for Lease - Foster City/Redwood Shrs

Strategically located near Stanford University and other major educational institutions, 200 Twin Dolphin has direct access to the world’s most highly educated and sought-after talent. The location is immersed within influential technology and life science centers which have funded, produced, and retained the world’s most iconic high growth companies. The building’s prominent corner offers iconic visibility in Redwood Shores with a unique opportunity for building signage. The site is carefully designed to preserve the connection with the surroundings and offers a functional layout for a research or technology organization. Among world-renowned technology and life science centers, Redwood Shores is prime innovation real estate. The corporate neighbors are among the most competitive companies in the world and create an excellent environment for collaboration and new ideas. Local restaurants, shopping, fitness, hotels and other services are available within close proximity. There is also easy access to Downtown San Carlos and Downtown Redwood City.

Date on Market:

2020-06-03

Irvine Coworking for Lease - Irvine/Tustin Legacy

Inspire the communities of tomorrow at UCI Research Park. This 21st-century hub of visionary businesses, pioneering start-ups, and global corporations is uniquely positioned to support a variety of forward-thinking teams and companies. From newly revitalized workspaces to a smart collection of on-campus amenities, UCI Research Park offers unmatched access to communities and talent at the forefront of new ideas, unlocking opportunities for innovation, connection and growth.

Property Type:

Office

Date on Market:

2020-01-23

Newark Flex for Lease

Newark Science Center at 8100 Jarvis Avenue has been converted into a state-of-the-art life science facility. The 53,259-square-foot building now boasts a stunning two-story lobby and front entrance with new finishes throughout. An expansive glass line offers sweeping views of the surrounding area. Inside, updated amenities abound, with renovated restroom cores and spec lab improvements on the second floor. The first floor remains in shell condition and ready for tenant customization. The new life science improvements can support biology uses rated for BSL3 (Biosafety Level 3) and chemistry uses. Upgraded property features ideal for a life science tenant include a grade-level loading area, distributed compressed air and vacuum, a 350 kW backup generator, distributed 220-volt outlets, and a hazardous waste storage area. For the most optimized airflow possible, the property has six air changes per hour in the general lab and a minimum of 10 changes per hour in instrument/TC (tissue culture) rooms. Strategically located, the Newark Science Center is adjacent to BioMed Realty's Pacific Research Center, home to an array of life sciences, office, high tech, and data center users to build synergy. Many advantageous high-tech companies are in the surrounding area, including Meta, Lucid Motors, Allogene Therapeutics, Boehringer Ingelheim, Neuralink, and Alexza Pharmaceuticals. This property is easy to access and is only three minutes from the Dumbarton Bridge (Highway 84), which connects to Palo Alto in 18 minutes. Many retail and dining amenities are near the Interstate 880 interchange, 2.5 miles away. Be in an ideal position for life science needs at Newmark Science Center, with new spec improvements now completed.

Date on Market:

2020-02-05

San Diego Flex for Lease - Mira Mesa/Miramar

Sorrento Ridge Research Park has been reinvented to form a dynamic environment, thoughtfully centered around creating a modern solution for life science users. The advantages provided by its strategic location, building efficiencies, canyon view, and outdoor connectivity will allow the end user to effectively advance research and discovery and promote innovation. • Spec lab improvements now complete! • 60,734 SF of spec lab & office • Divisible to 7,000 SF • House vacuum & compressed air • New 500kw generator • Shipping and receiving area with freight elevator • 3 loading areas, 2 grade level doors & 1 oversized double man door • 2 gas lines & 1 water line • Outdoor patio and amenity space with seating & BBQ • 2nd Floor private patio spaces • Central lobby with meeting & collaboration spaces • 3/1,000 parking ratio (expandable) & EV charging stations

Date on Market:

2019-07-15

Santa Clarita Office/Medical for Lease - Santa Clarita Valley

Property Type:

Office

Date on Market:

2023-01-26

Brisbane Flex for Lease - Brisbane/Daly City

Genesis 1000 Marina is a 6-story building offering ±114K square feet of Class A office and laboratory space. Located in the Sierra Point area of Brisbane, this property offers small to mid-size suites to the Bay Area market. Direct on and off ramps for easy access to US 101 allows for great commute times to South Bay or East Bay.

Property Type:

Office

Date on Market:

2026-02-26

San Diego Flex for Lease - Downtown

GENESIS - San Diego connects the region’s scientific community with the most modern and cutting-edge facilities designed to date with strategically engineered laboratories and highly designed office space. Over +/-200,000 RSF and eight-stories of Class A LEED Gold life sciences space, this project provides an environment for fundamental innovation and creation. Set amongst San Diego’s thriving downtown core, GENESIS - San Diego offers vibrant experiences at its doorstep – whether it’s the perfectly curated California-Mediterranean palette at Callie restaurant, the trolley station just steps from the front door or a baseball game at Petco Park. PREMIER LAB SPACE IN DOWNTOWN SAN DIEGO | Move In TODAY!

Property Type:

Office

Date on Market:

2021-03-12

Fontana Office/Medical for Lease - Airport Area

Dignity Medical Plaza offers an exceptional combination of visibility, accessibility, and built-in demand. Located in the heart of the Inland Empire’s retail and healthcare corridor, this two-story Class A medical plaza is positioned in The Shops at Sierra, a new mixed-use development providing walkable access to retail, dining, and service amenities. The building is ideal for urgent care, primary care, pediatrics, cardiology, imaging centers, dental practices, outpatient surgery, orthopedics, physical therapy, and concierge medicine, making it a prime choice for growing healthcare providers. Located at 17051 Sierra Lakes Parkway, Dignity Medical Plaza offers valuable direct frontage to Interstate 210 and easy connections to Interstates 15 and 215. Within a 5-mile radius, more than 333,000 residents enjoy average annual household incomes of $123,000, and nearly 97% are insured, creating a robust patient base. Three major hospitals are within 10 miles, and nearby destinations include CSU San Bernardino, Ontario International Airport, and Victoria Gardens.

Property Type:

Office

Date on Market:

2018-01-25

Sherman Oaks Office/Medical for Lease

Sherman Oaks Medical Plaza in Sherman Oaks, CA, offers immediate access to the Ventura and San Diego Freeways and is conveniently adjacent to Sherman Oaks Hospital and Grossman Burn Center. This professionally managed Class A medical building on the Sherman Oaks Hospital Campus is just 1/4 mile from the 101 and 405 Freeways. With three hospitals within 2 miles (Sherman Oaks Hospital, Encino Hospital, and Valley Presbyterian), this property provides easy accessibility to healthcare services. Additional amenities include a pharmacy with a state-of-the-art treatment area and a Dialysis Unit, making it an ideal choice for healthcare practitioners seeking medical office space.

Property Type:

Office

Date on Market:

2024-10-26

San Francisco Retail for Lease - Van Ness/Chinatown

SPECTACULAR VAN NESS AVENUE FRONTAGE Commercial Ground Floor The NEW 1100 Van Ness Avenue Medical Office Building is now open and serves as a major support facility for the new California Pacific Medical Center across the street. Located at one of the most dynamic intersections in San Francisco, Van Ness Avenue (HWY 101) is one of the top 3 highest traveled major arterials in San Francisco. Geary Street runs from Downtown San Francisco through the Richmond District—all the way to the Pacific Ocean. Listing may not include certain utilities, building services and property expenses. Flagship Opportunity Corner Space High Ceilings Signage Avaialble Food Use Strongly Desired (No Hood) Entrance on Van Ness & From Interior Lobby Located Near Starbucks Tenant Improvement Dollars Available for Qualified Tenants Just steps away from City Hall, War Memorial Opera House, Davies Symphony Hall, Polk Street and the affluent Pacific Heights and Russian Hill neighborhoods.

Property Type:

Office

Date on Market:

2025-05-13

San Diego Flex for Lease - UTC

Class A office and lab space in the highly desirable UTC submarket

Date on Market:

2025-06-10

Woodland Office, Office/Medical for Lease - Davis/Woodland

Woodland Innovation Center, located at 1100 Main Street in downtown Woodland, CA offers a rare opportunity to secure 40,000 square feet of highly visible, professionally designed Class A office space in the heart of the city’s historic core. Situated at a signalized intersection with strong vehicle and foot traffic, this freestanding, corner-lot building commands attention with its timeless architectural appeal and exceptional street presence—making it a perfect fit for businesses that value brand visibility, client accessibility, and a distinct sense of place. The building, built around a historic oak tree, is wrapped with expansive display windows that flood the interior with natural light and offer unmatched visibility to passersby. Inside, Woodland Innovation Center features an open and flexible layout that can be configured for a variety of professional uses—including creative agencies, corporate offices, nonprofit headquarters, business incubators, or client-facing service brands. High ceilings and preserved architectural details add a layer of sophistication that sets this property apart from more conventional office spaces, offering companies the chance to operate in an environment that feels both inspiring and functional. As part of Woodland’s revitalized downtown district, the property is surrounded by a vibrant mix of restaurants, cafes, retail, and public services—creating an active business ecosystem and a walkable environment for employees and clients alike. The city’s focused investment in downtown growth has fueled a wave of innovation and renewal, making this an ideal location for forward-thinking organizations looking to build deep roots in a flourishing community. On-street parking, nearby municipal lots, and immediate access to major roadways ensure seamless accessibility. Just 15 minutes from Sacramento International Airport, the building is perfect for frequent travelers. What makes Woodland Innovation Center truly unique is its ability to combine Class A quality with historic charm, offering tenants a freestanding identity and the flexibility to create a branded, memorable workplace. Whether you're a regional player expanding your footprint or a startup looking to launch in a dynamic, connected environment, Woodland Innovation Center, at 1100 Main Street provides a foundation for long-term success in the heart of Woodland.

Date on Market:

2025-11-18

San Diego Office, Flex for Lease - PB/Rose Canyon/Morena

Date on Market:

2025-11-12

Palo Alto Coworking for Lease

The Embarcadero Place is a 4-building campus which is bordered by the municipal golf course, airport, nature preserve and Baylands Athletic park. There is a delicatessen on site, 24-hour security, library and lunchroom on each floor, central courtyard with a pond and fountain and landscaped courtyard with outdoor seating at each building.This building was awarded an Energy Star label in 2015 and 2016 for its operating efficiency.

Property Type:

Office

Date on Market:

2016-04-12

San Diego Flex for Lease - Sorrento Mesa

5825 Oberlin is UNDER CONSTRUCTION to be converted to a new, spec-lab conversion project. Suite sizes ranging from 8,000 to 15,000 SF will be delivered turn-key with 55 / 45 lab-to-office ratios. Delivery is expected in Q2 2024. Contact brokers for more information. Additional details will be released soon.... The project is located in western Sorrento Mesa, ten minutes north of UTC and five minutes south of Del Mar Heights. Sorrento Mesa is home to some of the best known technology and innovative companies in San Diego.

Date on Market:

2024-04-22

Oxnard Coworking for Lease - Oxnard/Port Hueneme

The Campus at Topa Towers - Topa Financial Plaza Ventura Countys finest office environment with numerous on-site amenities with food court including Baja Fresh, The Habit, and The Tower Club, a private dining club on the 22nd floor of the Morgan Stanley Tower.

Property Type:

Office

Date on Market:

2014-02-11