282 Life Science Properties for Lease in California, USA

Pleasanton Office/Medical for Lease

Seta Place is a Class A office & medical building located at 4733 Chabot Drive in the heart of Pleasanton’s premier Tri-Valley office market. The property is zoned for medical, dental, and general office uses, making it well-suited for healthcare, life science, and professional service tenants. Sustainability features include on-site solar panels and advanced energy storage systems that help reduce operating costs. Tenants benefit from modernized interiors, upgraded common areas, and a secure, badge-less access system throughout the building. The property’s campus-style setting and professional environment create an attractive destination for both employees and visitors.

Property Type:

Office

Date on Market:

2026-06-20

Irvine Flex for Lease - Irvine Spectrum

This 96,000-square-foot freestanding flex/R&D building is divisible between 24,000 to 96,000 square feet. It is elevator served and has 5,000 square feet of climate-controlled warehouse space with 1 ground-level loading door. Furniture, fixtures, and equipment are available. The building features a dramatic lobby with 48,000 square feet of 2nd floor executive office space including a fitness center and large training room. 3,000 amps 277/480V power with on-site generator and battery backup system for uninterrupted power. Excellent for advanced manufacturing uses. Turn-key R&D lab space is on the first floor with C-arm, chem, and bio-hazard lab. 100% climate controlled facility with freezer and cooler space capabilities. The site features 384 parking stalls for a 4:1,000 parking ratio. Parking is expandable to accommodate larger companies. Property is institutionally owned. Longer lease term possible.

Date on Market:

2026-02-05

Hayward Flex for Lease - Hayward/Castro Valley

The property at 22421-22429 Hesperian Blvd, hayward is an exquisite, free-standing biotech, lab, and office building offering approximately 8,465 square feet of versatile space. Designed to accommodate both laboratory and office functions, the building can be demised into two separate units, providing flexibility for a range of tenants. Key features include lab spaces with benches already in place, enhanced BSL2 capabilities in one lab, nearly new roof and solar panels, modern HVAC packages, and perimeter security fencing. Monument signage is available for full-building users, and abundant parking supports both staff and visitors. The property is strategically located near the Hayward Executive Business Jet Airport and US 880, making it highly accessible for business operations. Additionally, the building is offered for lease with an option to buy, providing future ownership opportunities for interested parties.

Date on Market:

2026-01-09

Brisbane Office for Lease - Brisbane/Daly City

1800 Sierra Point 2nd floor office space. New office build out. Located in the center of the Bay Area life science cluster.

Date on Market:

2026-01-07

San Diego Office for Lease - UTC

Date on Market:

2025-12-11

San Diego Office/Medical for Lease - Uptown West/Park West

Signature medical/office opportunity in Bankers Hill new development with building signage and co-tenancy with UCSD and iStrive Research Lab This building is one of the few in the market that fully meets the 2030 State-required ASCE 41 earthquake standards—qualifying it for all State tenants and any tenant serving State employees, patients, or visitors 24/7 access with controlled entry and an advanced security system One of San Diego’s most desirable walkable neighborhoods with a dense population and breathtaking views of Downtown San Diego Bay, Point Loma, and the Pacific Ocean Exposure to adjacent neighborhoods including Little Italy, Balboa Park, Hillcrest, Mission Hills, and Downtown Located on the main thoroughfare connecting Balboa Park to I-5

Property Type:

Office

Date on Market:

2025-12-09

South San Francisco Office for Lease

650 Gateway Blvd South San Francisco, CA R&D building with ample lab space.

Date on Market:

2025-12-09

Redwood City Office for Lease

Strategically positioned in the heart of Silicon Valley, 700 Bay Road offers flexible space for a variety of users. This location is an ideal landing spot for growing life science and R&D companies. The cutting-edge mix of laboratory and office space is specifically designed for innovation. There are extensive laboratory facilities for biology labs, automation labs, vivarium, and tissue culture. This particular location is ideal for employees and visitors coming to the property. It is centrally located near many major universities, creating a substantial labor pool.

Date on Market:

2025-12-08

Berkeley Industrial for Lease

Berkeley Forge stands as Berkeley’s largest campus for deep tech, tough tech, and manufacturing innovation. The property comprises five buildings—1314, 1320, 1330, 1401, and 1420/1421—each designed for high-power, advanced manufacturing and R&D. The site benefits from proximity to UC Berkeley and the Gilman District, offering access to a diverse talent pool and vibrant amenities including breweries, wineries, art galleries, and retail. The property’s history is rooted in Berkeley’s manufacturing heritage, now revitalized with a focus on sustainability and knowledge-intensive production. Corporate neighbors include leading biotech, energy, and technology firms, reinforcing the campus’s position at the intersection of academia and industry. Berkeley Forge is ideal for organizations seeking a collaborative, future-ready environment in a space-constrained urban setting

Date on Market:

2025-12-04

Irvine Flex for Lease - Irvine Spectrum

3 Glen Bell Way is a highly efficient Class A building located in the heart of the Irvine Spectrum — one of Southern California’s most desirable corporate submarkets. Offering direct freeway visibility along the I-5 and immediate access to the 405 Freeway, the property provides exceptional convenience for workforce, executive, and client access. Constructed as a premier corporate headquarters, the building delivers a balanced mix of office, open workspace, and high-clear volume areas with robust power, infrastructure, and abundant parking. Its versatile configuration makes it ideally suited for R&D/Tech, Showroom/Design Center, Life Science, and Industrial/Office occupiers.

Date on Market:

2025-12-03

San Jose Flex for Lease - North San Jose

Date on Market:

2025-11-13

Agoura Hills Office/Medical, Office/Retail for Lease - Calabasas/Westlake Vill

Date on Market:

2026-06-01

Brisbane Office for Lease - Brisbane/Daly City

Strategically positioned along Highway 101 with massive freeway signage, the building provides exceptional identity and accessibility. Tenants benefit from a robust infrastructure, including 4000A normal power, a 1250kW generator, 200kVA UPS, and EV charging stations. Shuttle service to Caltrain and BART ensures seamless connectivity to the broader Bay Area, while on-site amenities such as a fitness center, wellness rooms, and café foster a dynamic work environment. Located just 12 minutes from downtown San Francisco, 7000 Marina Blvd offers proximity to major biotech clusters, top-tier dining, and hospitality options. With panoramic Bay views and direct access to the Bay Trail, this property delivers a rare combination of technical sophistication and lifestyle appeal—ideal for companies seeking a flagship presence in one of the nation’s most vibrant life science markets.

Date on Market:

2025-10-27

Davis Office for Lease - Davis/Woodland

Great window line Efficient suite Plenty of power High speed fiber Building and monument signage available Close proximity to Downtown Davis, UC Davis, numerous commercial & retail facilities and also Interstate 80 Bicycle and greenbelt access adjacent to Property Build-out includes 6 private offices, room for 9 cubicles in open area, large conference room, kitchen, copy/storage room, and small warehouse/storage space.

Date on Market:

2025-08-25

Westminster Industrial for Lease

This ±69,498 square foot freestanding industrial facility at 7474 Garden Grove Blvd offers a rare blend of visibility, power, and flexibility in the heart of Westminster. 22atBeach Industrial Center is located between the Beach Blvd and Golden West/Knott Ave exits on the Garden Grove (CA-22) Freeway. The site offers unique freeway frontage allowing you to promote your company/brand via a large, internally illuminated tenant sign readily visible to the freeway. Nearby amenities include a variety of dining, shopping and services options at CA 22 and Beach Blvd, and convenient access to public transit and community services—making this a prime location for both workforce convenience and business exposure. The 69,498 sf building features ±6,000 SF two-story office, a large, fenced yard, seven (7) dock-high loading doors—three (3) with pit levelers—and one (1) oversized 14'W x 16'H grade-level door. It is an ideal location for streamlined logistics, aerospace/defense, research and development, and even retail uses. This Premium building includes 2,000 amps of 277/480V power (expandable to 4,000 amps), extra heavy slab and 32-foot minimum clear height. With freeway frontage, parking for up to 120 vehicles and flexible CM zoning supporting both light industrial, commercial and retail uses, this property checks all the boxes for a variety of uses.

Date on Market:

2025-08-21

Millbrae Office for Lease - San Bruno/Millbrae

Divisible office space. Mixed Use Office Building w/Ground Floor retail.

Date on Market:

2025-10-06

South San Francisco Flex for Lease

Join a premier life science campus with the versatile spec suites available for lease at East Grand Avenue in South San Francisco, California. Coming available in September of 2026, these modern spaces include options for 22,250 and 37,532 square feet, offering an ideal canvas for growing teams and institutional businesses. This incredible business destination offers a range of exceptional on-site amenities that form an idyllic and energizing hub for corporate activity. Tenants enjoy access to an activated wellness center, a restaurant, sports courts, and a 300-person conferencing center. There is also abundant on-site parking available with EV charging stations, as well as generous outdoor space with outdoor walking trails and lush landscaping. Situated in a prominent location close to the Highway 101 interchange, this rare offer places businesses in an easily accessible commercial hub. The campus is just a short walk to the SSF Caltrain station, and less than 10 minutes from SFO airport. The surrounding area presents a wide array of desirable urban amenities, including top-rated shopping, dining, recreation, and hotels.

Date on Market:

2026-05-12

Thousand Oaks Office for Lease - Thousand Oaks/SE County

2101 Corporate Center Drive offers a premier life sciences and office environment in the Newbury Park area of Thousand Oaks. This Class B property is designed to accommodate research, development, and office operations, featuring flexible configurations and modern infrastructure. The building provides three available suites, including turnkey lab/office space and warm shell options suitable for chemistry and biology labs or technology-driven uses. The property spans 3.26 acres and includes 196 parking spaces, delivering a parking ratio of nearly 4 spaces per 1,000 square feet. Tenants benefit from a professional setting with LEED certification, supporting sustainability and operational efficiency. The site’s location within the Conejo Valley biotech corridor offers proximity to a robust life sciences ecosystem, including major pharmaceutical and biotech firms. Conveniently positioned near U.S. 101, the property ensures excellent regional connectivity to Greater Los Angeles and Ventura County. Nearby amenities include dining, retail, and hospitality options, enhancing convenience for employees and visitors. With immediate availability and negotiable lease terms, 2101 Corporate Center Drive is an ideal choice for companies seeking a high-quality, adaptable space in a thriving innovation hub.

Property Type:

Flex

Date on Market:

2026-07-10

Daly City Retail for Lease - Brisbane/Daly City

Property Type:

Flex

Date on Market:

2025-07-30

Fremont Office for Lease

Class A building designed for Life Sciences, STEM, office, data center, and high-tech users, featuring robust infrastructure with 4,000 amps at 480V per building and up to 3,000 additional amps of capacity based on an existing load study. Amenities include a freight elevator, secure tenant lobby, open office space, lab support rooms, private offices, conference rooms, kitchenette, break room, and storage/copy room. Tenants also benefit from strong HVAC capacity, EV charging stations, fitness center, and a daily shuttle service to BART and ACE Rail.

Date on Market:

2025-07-09

Berkeley Office for Lease

The property benefits from convenient access to major transportation routes, BART connections via local shuttle services, the Amtrak Capitol Corridor, and the amenities of West Berkeley. Nearby dining, retail, fitness, recreation, and campus services contribute to an environment that supports employee recruitment, retention, and daily convenience.

Date on Market:

2025-06-25

San Diego Office, Flex for Lease - Mission Valley

Date on Market:

2025-06-03

Hawthorne Office for Lease - Hawthorne/Gardena

Located at a prominent intersection of Hawthorne Blvd. & W. 136th St. in populated area. On and off-ramp access from the 105 Freeway & a few minutes away from Hawthorne Airport & 405 Freeway National & regional retailers in the vicinity: Denny’s, El Pollo Inka, Carl’s Jr., Dunkin’ Donuts, Bossa Nova, Autozone, O’Reilly Auto Parts, NAPA Auto Parts, Planet Fitness, 7-Eleven, True Value Hardware, CosmoProf & more. Available for OFFICES, medical, defense contractors, educational, events, assembly, school, research lab, religious complex, film or sound editing studio (subject to City approval), etc.

Date on Market:

2025-05-05

Walnut Creek Office/Medical for Lease - Walnut Creek-Shadelands

Property Type:

Flex

Date on Market:

2025-04-24