461 Life Science Properties for Lease in California, USA

San Diego Office for Lease - Rancho Bernardo

Innovation Corporate Center offers a premier Class A office and corporate headquarters campus in the heart of Rancho Bernardo, one of San Diego’s most desirable business districts. Spanning eight architecturally cohesive buildings totaling ±467,000 RSF, this master-planned environment is designed to support office, R&D, life science, and biotech users with flexible floorplates and collaborative layouts. Strategically positioned just off I-15 at Camino Del Norte and Carmel Mountain Road, the campus provides immediate freeway access and proximity to over one million square feet of adjacent retail, dining, and hospitality amenities. Tenants benefit from polished concrete floors, exposed ceilings, and abundant natural light, with suites offering a mix of private offices, conference rooms, IT infrastructure, and open workspaces. Several suites feature prominent lobby entrances and the potential for roll-up doors to support light industrial or lab functions. The surrounding Rancho Bernardo area is known for its highly educated workforce, scenic open space, and proximity to Palomar Medical Center Poway, making it ideal for life science and tech-oriented tenants. With a blend of modern design, functional efficiency, and amenity-rich surroundings, Innovation Corporate Center is a compelling choice for companies seeking a dynamic and scalable workplace.

Date on Market:

2025-09-24

Tarzana Retail for Lease

±2,500 SF of Retail in a newly renovated center, Located on the SEC of a high traffic corridor ±70,000 Car Count, 100 feet from the Orange Line Station, End Cap Available. Property is well suited for national, regional, and local tenants for high-traffic volume uses. Cold kitchen restaurant, take-out, food. Short Term available. The east San Fernando Valley light rail project is under construction, which will run north-south from the city of San Fernando to Van Nuys. The light rail will then connect to the current metro lines running east-west along Oxnard Blvd, directly adjacent to this center. This project will make it much more convenient to travel hassle free throughout the SFV in a much shorter time span and will vastly increase traffic to the center. Prospective tenants will benefit greatly from the increased daily traffic and will receive much more exposure across the San Fernando Valley.

Date on Market:

2025-02-28

Agoura Hills Office for Lease - Calabasas/Westlake Vill

Free parking 4/1,000 and additional available. Campus environment with extensive landscaping, integrated balconies and terraces in select suites. T-1 and fiber optics available.

Date on Market:

2026-02-26

Ventura Office for Lease

A brand-new industrial/office building in Ventura, CA. The approximately 10,104sf Industrial space is an ideal opportunity for a restaurant, brewery, or entertainment venue to build their custom concept. A conditional use permit is in place allowing the sale of alcohol and a restaurant use. The health department has approved the plans for a kitchen. Construction permits are in place. Additionally, there is a secured, approximately 3,000sf patio available (for an additional fee). Traditional industrial uses will also be considered. The second story (elevator served) class A office suites are some of the finest in Ventura with excellent views of the nearby golf course and Pacific ocean. Only two office units remain. The 24,035 sq ft building sits on an approximately 2.8 acre lot. Fantastic Olivas Park frontage directly across from the golf course. 67 onsite parking spaces. Property is sprinklered, and includes two ground-level rollup doors, and an elevator. Excellent 101 Fwy access and close proximity to amenities. High speed fiber Internet available.

Property Type:

Flex

Date on Market:

2019-12-06

Los Angeles Office for Lease - Koreatown

Discover newly renovated office spaces in the vibrant K-Town and Mid-Wilshire area. This prime location on Wilshire Blvd offers high visibility with signage opportunities, perfect for boosting your business presence. Small office spaces, which are rare to find, are now available at competitive rates! Enjoy exclusive move-in promotions and excellent parking options, including one hour free for customers. Elevate your business in this prestigious, high-traffic location with unbeatable perks. Schedule a tour today and secure your spot!

Date on Market:

2026-06-15

Glendale Office for Lease

611 North Brand Boulevard is a 14-story, 364,128 square foot building featuring state-of-the-art office amenities and retail space in the heart of Glendale's Financial District.

Date on Market:

2025-07-01

La Verne Flex for Lease - Eastern SGV

La Verne Business Park, located at 2061–2079–2125 Wright Avenue in La Verne, California (near the corner of Wright Avenue and Fairplex), offers office, R&D, warehouse, and industrial spaces for lease ranging from 1,248 to 5,440 square feet. This professional business park environment is situated within Los Angeles County and features excellent large truck access to all buildings, with rear areas designed for loading and unloading large storage containers. Tenants benefit from ample on-site parking with large stalls, professional office suites equipped with air conditioning and heating, and warehouses with foil-insulated ceilings and skylights for energy efficiency and natural light. Each unit includes minimum 10' x 12' ground-level loading doors and ceiling clearance heights of 14 to 16 feet. Power is robust, with 100–200 Amp, 120/208 Volt, 3-phase service available. The property offers easy access to major freeways (10, 210, 57, 60, 71, and 210/30), individual tenant signage, and DSL/internet technology. Permitted uses include office, research and development, medical, distribution, wholesale, light manufacturing, and many other business types. The park boasts an attractive approach as the gateway to a master-planned business park, with a quality and secure location in the City of La Verne. On-site amenities include a restaurant for breakfast and lunch

Date on Market:

2026-06-05

Mountain View Office for Lease

Office Building with Short Term Lease Availability 3 conference rooms (103, 215, 210) Bathrooms w Showers (123, 124, 125, 127) Kitchen Autoclave (121) and Ice Machine Labs include Vacuum, De-ionized Water, Compressed Air, Natural Gas, Emergency Back-up generator - 150 Kilowatts Office Building with Short Term Lease Availability Prime Mountain View Location Near Highway 101 and Highway 85

Date on Market:

2026-03-04

South San Francisco Office, Flex for Lease

This freestanding office and warehouse property offers a unique opportunity for tenants seeking flexibility and advanced infrastructure in South San Francisco’s growing life science and technology corridor. The building spans approximately 40,606 square feet, including a newly built-out office component with high-end finishes, a remodeled lobby, and functional common spaces. Designed for modern occupiers, the property features an advanced HVAC system with dedicated outside air and MERV 13 filters, individual suite thermostats, and zoned air handling to ensure optimal indoor conditions. The warehouse portion offers approximately 19,798 SF with 22-24 foot clear heights, supported by generous 1,600A / 3-phase power to accommodate specialized or high-intensity operations. Enhanced security is provided through monitored systems and controlled access points. Located within the South San Francisco life science cluster, the property offers immediate access to US-101, with close proximity to major transportation nodes including Caltrain, BART, and the South San Francisco Ferry Terminal. Tenants will benefit from nearby amenities such as The Shops at Tanforan, numerous dining options, and proximity to global biotech leaders like Genentech. Parking is ample with 102 dedicated spaces.

Date on Market:

2017-11-16

San Diego Flex for Lease - Del Mar Hts/Carmel Valley

Champions of the West is a three-story, Class A coastal office building that is located right off the I-5 an access to Highway 56. The property has an atrium style design offering extensive glass line with abundant natural light.

Date on Market:

2026-05-05

Colton Office, Office/Medical for Lease - San Bernardino

Mount Vernon Business Center is a single-story office and medical complex designed to accommodate a wide range of professional users. The property features expansive parking, making it an excellent option for businesses with high parking requirements such as medical practices, accounting firms, and legal offices. Its strategic location at the intersection of South Mount Vernon Avenue and Santo Antonio Drive provides quick access to I-10 and I-215, ensuring strong regional connectivity. The center includes multiple buildings with flexible floor plans, professional signage opportunities, and monument signage for enhanced visibility. Tenants benefit from a well-maintained environment in a vibrant business community near major retailers, including Walmart SuperCenter, and numerous local amenities. With its combination of accessibility, functionality, and professional appeal, Mount Vernon Business Center offers an ideal setting for businesses seeking convenience and operational efficiency.

Date on Market:

2026-04-29

Los Angeles Medical for Lease - Century City

Century City Medical Plaza is an 18 story Class A Medical Office Building, approximately 200,000 rentable square feet, located in the heart of Century City, Los Angeles and within walking distance from hotels, restaurants, and shopping venues. CCMP is adjacent to Westwood and Beverly Hills, minutes from the 405 and 10 freeways and walking distance from the under-construction Metrolink Century City station. CCMP offers prestigious medical office space ranging from 800 square feet to 11,000 square feet whole-floors. Amenities on-site include a pharmacy, diagnostic lab, radiology/MRI facility, restaurant, dry cleaners, and car wash/detailing service. CCMP has a state-of-the-art Fire-Life-Safety and sprinkler system. There are four levels of subterranean parking offering space for over 800 cars and valet service for patients and visitors. CCMP has 24-hour security guard service and 24-hour CCTV live monitoring, controlled access after-hours, and the property manager is on-site. CCMP utilizes an online tenant portal and work order management system for prompt response to tenant service requests.

Property Type:

Office

Date on Market:

2026-05-05

San Diego Office for Lease - Sorrento Mesa

Nestled in the heart of San Diego’s thriving Sorrento Mesa submarket, 6725 Mesa Ridge Road offers a serene canyon setting paired with exceptional corporate functionality. This ±32,570 square foot professional office building is ideal for tenants seeking a tranquil yet connected workspace. The available ±1,082 RSF suite (Suite 200) delivers flexible floor plan options, abundant natural light, and scenic views that enhance productivity and comfort. Tenants benefit from immediate access to major transportation corridors including I-805, I-5, I-15, and Hwy-56, ensuring seamless connectivity across the region. The property is surrounded by a robust amenity base, with hotels, restaurants, banking services, and two delis within walking distance. On-site building management ensures responsive service and operational ease, while the IL-2-1 zoning supports a wide range of professional uses. Whether you're a growing firm or an established business seeking a strategic foothold in San Diego’s innovation corridor, 6725 Mesa Ridge Road offers a compelling blend of location, flexibility, and value.

Date on Market:

2025-09-30

Lynwood Office/Medical for Lease - Mid-Cities

On campus of St. Francis hospital, plenty of secured parking with full time on site maintenance and security guard. Ancillary services such as radiology with brand new MRI, CT and X-Ray, laboratory with draw station, and pharmacy, all present in the building. Across the street from St. Francis hospital. Walking distance to restaurants and shops, with good visibility and access from Martin Luther King Blvd and the hospital.

Property Type:

Office

Date on Market:

2025-07-15

South San Francisco Office for Lease

Excellent office sublease with water views. 3 private offices, open space, and shared conference room and shared kitchen

Date on Market:

2026-06-08

San Francisco Industrial for Lease - South of Market

Unique opportunity to lease a single identity permitted turn key laboratory in the Heart of San Francesco with designated parking. The space was completely renovated in 2017 and was designed by CAC Architects for Blackthorn Therapeutics. The building is in turn key condition with 9 fume hoods, back up generator, 800 amps of power, server room, bio-waste room, sprinklered, full HVAC, 3 conference room, 5 private offices, 1 biology lab, 1 tissue culture lab, computational chimerical lab for 14 workstations. 21 office workstations, 4 ADA bathrooms with showers.

Date on Market:

2026-06-05

South San Francisco Office for Lease

Property Type:

Flex

Date on Market:

2026-06-03

Los Angeles Flex for Lease - Glendale

HATCHlabs @ 5370 Alhambra is Los Angeles's original purpose-built commercialization infrastructure facility — a 2020 APA Los Angeles Planning Award winner recognized for Economic Planning and Development, and the first privately developed, multi-tenant technical lab facility in the East LA Bioscience Corridor. Supported at inception by the Mayor's Office of the City of Los Angeles, the Los Angeles Economic Development Corporation, and the California Life Sciences Association, this is not a retrofitted warehouse or converted office building. It was engineered from the ground up for companies doing real technical work. Built for Companies That Have Outgrown Academic Labs, Incubators, and Accelerators The most persistent gap in the Los Angeles innovation ecosystem is the space between an incubator bench and a full institutional campus. HATCHlabs was designed specifically to fill that gap. Private furnished suites starting under 1,600 SF give early-stage and growing companies dedicated, lockable, operationally capable space without the capital commitment, long-term lease obligation, or buildout timeline of larger facilities. Flexible lease terms — including short-term options — are available. Suites are combinable as companies grow. This is the right step for a team that has proven its concept and needs to operate independently, but is not yet ready for a 10,000 SF institutional lab commitment. Infrastructure That Took Years and Significant Capital to Build — Already In Place Finding technical space in Los Angeles that actually supports lab operations is genuinely difficult. Generic flex industrial buildings do not have what HATCHlabs has. Every suite at 5370 Alhambra includes direct venting and floor drains. The building delivers 800/1600A, 208Y/120V three-phase power with ceiling heights ranging from 12'6" to 24' clear. BSL1 and BSL2 laboratory operations are supported across multiple suites. A City of LA permitted 40 KVA / 32 KW three-phase standby generator with Level 2 acoustic enclosure provides critical backup power to lab suites — installed, permitted, and operational. High-speed fiber, loading access, and a shared lobby are standard. Shared building infrastructure reduces individual tenant cost and buildout complexity: conference room, freezer capacity, chemical storage, waste handling, and heavy ventilation and mechanical systems are available across the tenant community. A technical company moving into HATCHlabs does not need to spend 6 to 18 months or significant capital building the infrastructure it needs to operate. It is already here. Currently Available — 8,679 SF Across Four Suites Suite A2: 1,724 SF — Turnkey BSL2 lab Suite B: 3,633 SF — Turnkey BSL2 lab, largest single suite, combinable Suite C2: 1,583 SF — Turnkey BSL2 lab, combinable Suite H: 1,739 SF — Turnkey office, convertible to lab or makerspace All suites are furnished. Suites are combinable and divisible. Flexible and short-term lease structures available. Who Operates Here HATCHlabs serves diagnostics and clinical testing companies, cosmetic and formulation companies, medtech and medical device firms, hardtech and robotics companies, physical AI and hardware developers, climate tech and environmental testing firms, food science and nutraceutical companies, analytical and technical testing labs, university spinouts, translational research teams, and founder-led companies that require serious technical infrastructure to operate. Location — East Los Angeles Bioscience Corridor 5370 Alhambra Avenue, El Sereno, Los Angeles, CA 90032. Situated within the LA Bioscience Hub, with direct proximity to Grifols Pharmaceuticals (1 mi), Cal State LA (2 mi), LA BioSpace Incubator (2 mi), USC Keck Medicine (3 mi), LA Cleantech Incubator (6 mi), Caltech (6 mi), Pasadena Bio Collaborative (8 mi), and City of Hope (15 mi).

Date on Market:

2026-05-29

Pleasanton Flex for Lease

Located at the entrance of Valley Business Park, this industrial property offers a highly functional layout with excellent access and amenities. Featuring up to ±30,168 SF of space available, the building is equipped with four roll-up grade-level doors and a double dock for efficient loading and distribution operations. The clear height of 18 feet is suitable for a variety of industrial and light manufacturing uses. The property provides signage opportunities at both the building and monument, ensuring visibility within the business park setting. Tenants can benefit from robust power specifications with 277/480V and up to 1,200 AMPS (tenant to verify), enabling operations that require heavy electrical loads. Its position near downtown Pleasanton offers access to numerous amenities including shopping centers, dining options, and business services. Strategically situated in the Tri-Valley area, the property ensures proximity to major transportation corridors. I-580 and I-680 are minutes away, offering excellent connectivity for local and regional distribution. Oakland International Airport is about 30 minutes away, while San Francisco and San Jose airports are also within reasonable reach, facilitating convenient business travel and logistics.

Date on Market:

2026-05-11

El Segundo Flex for Lease

236 California Street in El Segundo, CA, is a single-story industrial property measuring approximately 14,300 square feet and is classified for light industrial use. It is located in the El Segundo/Beach Cities submarket within Los Angeles County, offering access to major highways and situated about 3.2 miles from Los Angeles International Airport. Power Specs: 480V 1200A 3 -phase + Panel A 120/208 volt 3-phrase Panel B 240 volt 3-phase Panel (under mezzanine south) 120V 200 amps Panel (under mezzanine north) 120 volt sub panel J-Box

Date on Market:

2026-05-01

San Diego Flex for Lease - Sorrento Mesa

Date on Market:

2026-04-28

San Diego Retail for Lease - UTC

CVS Anchored shopping center in Unversity City, surrounded by luxury apartment communities and high value single family residences. Univeristy City is an employment hub for San Diego with office parks, healthcare and research facilities, providing daytime traffic.

Date on Market:

2026-04-22

Palo Alto Flex for Lease

Property Type:

Office

Date on Market:

2026-04-15

Fremont Industrial for Lease

Locationed on the Corner of Osgood Road & Darby Commons, Former semiconductor manufacturing/R&D facility with existing infrastructure (DI water System, CDA System,Chillers, etc.)

Date on Market:

2026-04-14