Commercial Real Estate in California available for lease

284 Life Science Properties for Lease in California, USA

Life Science Properties for Lease in California, USA

More details for 2600 Hilltop Dr, Richmond, CA - Flex for Lease

Building B - Life Science Acceleration Campus - 2600 Hilltop Dr

Richmond, CA 94806

  • Life Science
  • Flex for Lease
  • 280 - 24,862 SF
  • 23 Spaces Available Now
  • Reception

Richmond Flex for Lease - Richmond/San Pablo

Davide F. Pio and Edder Barcenas of BCRE proudly present Buildings A, B, and C Annex at JOINN Innovation Park, located at 2600 Hilltop Dr in Richmond, CA, for lease. Set within a ±350,000 sq. ft. biotechnology acceleration campus at the center of one of the largest life science clusters in the United States, the offering is ideal for research organizations, emerging biotech firms, and established life science companies seeking purpose-built lab and office space. Building B totals ±102,000 sq. ft. of life science space configured as both biological and chemical laboratories, available in suites from ±300 to ±2,400 sq. ft. with office components. The scalable footprints allow tenants the ability to right-size at entry and expand within the same building as programs advance. Building A offers ±20,000 sq. ft. of office space with private offices and conference rooms encircling an open-floor plan currently set up as cubicles. The two buildings are joined by a connecting atrium with an available on-campus cafeteria. The campus operates as a fully integrated biotech ecosystem combining preclinical, CRO, and GMP/CDMO capabilities alongside cold chain transportation and logistics services. Companies working from discovery through preclinical can source much of that work on site rather than through outside vendors, cutting both handoff time and shipping risk while the campus is secured by 24/7 security patrol. The campus anchors the northern end of the Berkeley–Emeryville life science corridor, home to over 150 biotech firms and 1.45 million sq. ft. of wet lab space. Lying within Richmond Parkway and Hilltop Drive, there are multiple Highway 80 and 580 access points nearby that allow for a short commute to Berkeley, Oakland, San Francisco, and Marin County.

Contact:

BCRE

Date on Market:

2026-08-08

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More details for 468 Littlefield Ave, South San Francisco, CA - Office, Flex for Lease

468 Littlefield Ave

South San Francisco, CA 94080

  • Life Science
  • Flex for Lease
  • 2,903 - 44,311 SF
  • 1 Space Available Now
  • Private Restrooms
  • Reception

South San Francisco Office, Flex for Lease

468 Littlefield Avenue presents a rare opportunity to lease a full-building life science, research and development, or office facility in South San Francisco, one of the Bay Area's most established biotechnology and innovation corridors. The property consists of approximately 44,311 square feet across three levels and offers flexibility for a wide range of occupiers seeking laboratory support, research operations, office headquarters, or technology-focused workspace. The building is offered with most equipment removed and is positioned as a tenant-improvement-ready opportunity, allowing users to customize the environment to meet operational requirements. Existing infrastructure includes substantial electrical capacity with a current 900-amp service supported by a 750 KVA transformer, along with PG&E-approved capacity for future expansion to 3,000 amps. Building systems include multiple boilers, chillers, air handling units, and exhaust systems that support demanding operational requirements. The location provides convenient regional connectivity with immediate access to Highway 101, proximity to Highway 280 and Highway 380, and access to Caltrain, ferry service, and San Francisco International Airport. Occupiers benefit from nearby restaurants, hotels, recreation amenities, and services throughout South San Francisco's Oyster Point and Lindenville districts. The property's combination of infrastructure, flexibility, transportation access, and positioning within a recognized life science market makes it well suited for organizations seeking a strategic Bay Area presence.

Contact:

Kidder Mathews

Date on Market:

2026-07-29

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More details for 499 Forbes Blvd, South San Francisco, CA - Office for Lease

499 Forbes Blvd

South San Francisco, CA 94080

  • Life Science
  • Office for Lease
  • 18,000 - 58,000 SF
  • 1 Space Available Now
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More details for 6335 Nancy Ridge Dr, San Diego, CA - Flex for Lease

6335 Nancy Ridge Dr

San Diego, CA 92121

  • Life Science
  • Flex for Lease
  • 4,286 SF
  • 1 Space Available Soon
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More details for 2122 Bryant St, San Francisco, CA - Flex for Lease

2122 Bryant St

San Francisco, CA 94110

  • Life Science
  • Flex for Lease
  • 2,000 - 2,500 SF
  • 1 Space Available Now
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More details for 400 Oyster Point Blvd, South San Francisco, CA - Office for Lease

Oyster Point Marina Plaza I - 400 Oyster Point Blvd

South San Francisco, CA 94080

  • Life Science
  • Office for Lease
  • 1,000 SF
  • 1 Space Available Now
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More details for 100 Channel St, San Francisco, CA - Retail for Lease

LUMA Hotel San Francisco - 100 Channel St

San Francisco, CA 94158

  • Life Science
  • Retail for Lease
  • 7,000 SF
  • 1 Space Available Now
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More details for 480 Forbes Blvd, South San Francisco, CA - Office for Lease

Building A - 480 Forbes Blvd

South San Francisco, CA 94080

  • Life Science
  • Office for Lease
  • 34,754 SF
  • 1 Space Available Soon
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More details for 5370 Alhambra Ave, Los Angeles, CA - Flex for Lease

HATCHlabs - 5370 Alhambra Ave

Los Angeles, CA 90032

  • Life Science
  • Flex for Lease
  • 1,583 - 8,679 SF
  • 1 Space Available Now

Los Angeles Flex for Lease - Glendale

HATCHlabs @ 5370 Alhambra is Los Angeles's original purpose-built commercialization infrastructure facility — a 2020 APA Los Angeles Planning Award winner recognized for Economic Planning and Development, and the first privately developed, multi-tenant technical lab facility in the East LA Bioscience Corridor. Supported at inception by the Mayor's Office of the City of Los Angeles, the Los Angeles Economic Development Corporation, and the California Life Sciences Association, this is not a retrofitted warehouse or converted office building. It was engineered from the ground up for companies doing real technical work. Built for Companies That Have Outgrown Academic Labs, Incubators, and Accelerators The most persistent gap in the Los Angeles innovation ecosystem is the space between an incubator bench and a full institutional campus. HATCHlabs was designed specifically to fill that gap. Private furnished suites starting under 1,600 SF give early-stage and growing companies dedicated, lockable, operationally capable space without the capital commitment, long-term lease obligation, or buildout timeline of larger facilities. Flexible lease terms — including short-term options — are available. Suites are combinable as companies grow. This is the right step for a team that has proven its concept and needs to operate independently, but is not yet ready for a 10,000 SF institutional lab commitment. Infrastructure That Took Years and Significant Capital to Build — Already In Place Finding technical space in Los Angeles that actually supports lab operations is genuinely difficult. Generic flex industrial buildings do not have what HATCHlabs has. Every suite at 5370 Alhambra includes direct venting and floor drains. The building delivers 800/1600A, 208Y/120V three-phase power with ceiling heights ranging from 12'6" to 24' clear. BSL1 and BSL2 laboratory operations are supported across multiple suites. A City of LA permitted 40 KVA / 32 KW three-phase standby generator with Level 2 acoustic enclosure provides critical backup power to lab suites — installed, permitted, and operational. High-speed fiber, loading access, and a shared lobby are standard. Shared building infrastructure reduces individual tenant cost and buildout complexity: conference room, freezer capacity, chemical storage, waste handling, and heavy ventilation and mechanical systems are available across the tenant community. A technical company moving into HATCHlabs does not need to spend 6 to 18 months or significant capital building the infrastructure it needs to operate. It is already here. Currently Available — 8,679 SF Across Four Suites Suite A2: 1,724 SF — Turnkey BSL2 lab Suite B: 3,633 SF — Turnkey BSL2 lab, largest single suite, combinable Suite C2: 1,583 SF — Turnkey BSL2 lab, combinable Suite H: 1,739 SF — Turnkey office, convertible to lab or makerspace All suites are furnished. Suites are combinable and divisible. Flexible and short-term lease structures available. Who Operates Here HATCHlabs serves diagnostics and clinical testing companies, cosmetic and formulation companies, medtech and medical device firms, hardtech and robotics companies, physical AI and hardware developers, climate tech and environmental testing firms, food science and nutraceutical companies, analytical and technical testing labs, university spinouts, translational research teams, and founder-led companies that require serious technical infrastructure to operate. Location — East Los Angeles Bioscience Corridor 5370 Alhambra Avenue, El Sereno, Los Angeles, CA 90032. Situated within the LA Bioscience Hub, with direct proximity to Grifols Pharmaceuticals (1 mi), Cal State LA (2 mi), LA BioSpace Incubator (2 mi), USC Keck Medicine (3 mi), LA Cleantech Incubator (6 mi), Caltech (6 mi), Pasadena Bio Collaborative (8 mi), and City of Hope (15 mi).

Contact:

ASG Real Estate, Inc.

Date on Market:

2026-05-29

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More details for 1300 Rancho Conejo Blvd, Newbury Park, CA - Office, Flex for Lease

1300 Rancho Conejo Blvd

Newbury Park, CA 91320

  • Life Science
  • Industrial for Lease
  • 3,507 - 52,536 SF
  • 1 Space Available Now
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More details for 236 California St, El Segundo, CA - Flex for Lease

236 California St

El Segundo, CA 90245

  • Life Science
  • Flex for Lease
  • 14,300 SF
  • 1 Space Available Soon
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More details for 674 Cliffside Dr, San Dimas, CA - Office for Lease

Walnut Creek Business Park - 674 Cliffside Dr

San Dimas, CA 91773

  • Life Science
  • Office for Lease
  • 4,348 SF
  • 1 Space Available Now
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More details for 1722 S Coast Hwy, Oceanside, CA - Industrial for Lease

The Times - 1722 S Coast Hwy

Oceanside, CA 92054

  • Life Science
  • Industrial for Lease
  • 3,866 SF
  • 1 Space Available Now
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More details for 6500 Kaiser Dr, Fremont, CA - Flex for Lease

6500 Kaiser Dr

Fremont, CA 94555

  • Life Science
  • Flex for Lease
  • 21,300 SF
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More details for 720 Dubuque Ave, South San Francisco, CA - Industrial for Lease

720 Dubuque Ave

South San Francisco, CA 94080

  • Life Science
  • Industrial for Lease
  • 124,000 SF
  • 1 Space Available Now
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