45 Life Science Properties for Lease in Houston, TX, USA

Houston Office/Medical for Lease - South Main/Medical Center

Travis Medical Center is strategically located right at the gateway to the world’s largest medical complex, offering unparalleled visibility and accessibility. Under new ownership, this premier medical office building is being reimagined to deliver an elevated experience for healthcare professionals and their patients. Travis Medical Center is undergoing a bold transformation. A stunning new lobby and modernized exterior are just the beginning. A multimillion-dollar renovation is underway, transforming the lobby, portico breezeway for covered tenant and patient main entrance access, and streetscape with a modern, design-forward aesthetic. Convenience is already a priority with on-site parking available and will soon be elevated further with the addition of valet services — ensuring seamless access for both physicians and patients. Travis Medical Center offers several move-in-ready, second-generation medical suites designed for a variety of specialties, including dental, dermatology, hematology, podiatry, and pediatrics. For those looking to customize their space, white-box and shell spaces are also available. Professionally managed by industry leader Hines, the property offers on-site engineering and security teams, ensuring seamless day-to-day operations and peace of mind for tenants. Flexible leasing options are available, with negotiable tenant improvements, competitive lease rates, and short-term options to accommodate a range of needs. Annual base rental rates range from $22.00 to $28.00 per square foot on a Full-Service Gross lease, significantly below the average rents in the TMC. Travis Medical Center offers unmatched convenience. With direct connectivity to the adjacent Hilton, tenants enjoy access to a state-of-the-art fitness center, Starbucks Barista kiosk, pool deck with fire pits, cocktail bar, Herb-N-Kitchen delicatessen, catering services, and conference facilities. The property’s location on the edge of the TMC makes it one of the most accessible buildings in the world’s largest medical complex. At the Epicenter of Global Medical Innovation: The Texas Medical Center Spanning 1,400 acres, the Texas Medical Center is home to over 375,000 professionals, 60 medical institutions, and 300+ cutting-edge research labs. The Travis Medical Center is surrounded by renowned institutions such as Texas Children’s Hospital, St. Luke’s Health, and Houston Methodist, placing your practice among the elite in healthcare. With 20 universities and colleges—including Baylor College of Medicine and Rice University—located within TMC, tenants benefit from exceptional opportunities for research, education, and collaboration. With over 10 million patients served annually at TMC, Travis Medical Center places practices at the forefront of medical excellence - boosting both visibility and prestige. Inquire today to elevate your practice in the heart of innovation.

Property Type:

Office

Date on Market:

2023-11-13

Kingwood Multiple Space Uses for Lease - Kingwood/Humble

Kingwood Tech Center is open for a broad range of creative uses and can be divided to suit any size of tenant. Uses are possible for industrial, specialty retail, restaurant / commercial kitchen , day care centers , a life science office , medical office, and much more. Ownership is open to negotiable creative deals for build-outs and TI allowances. Utilities are included in rent for additional savings, on top of this being listed at an affordable rate. Within a 10-mile radius for spaces of this size average industrial/flex rates are $12.20/SF and office rates are $22.55/SF, markedly higher than the rates at Kingwood Tech Center. Located at 220001 Northpark Drive, this property is directly aligned in the path of Greater Houston growth. Migration to the area has skyrocketed as demographic data shows the number of households within a 3-mile radius grew by roughly 34% from 2010 to 2023 and is expected to jump another 6% by 2028. Population growth and new development from Houston have trended northward as communities like The Woodlands, Spring, Humble, and Conroe have gained national renown for their popularity. Tenants of Kingwood Tech Center can easily connect to these enclaves with direct access to Interstate 69 and Grand Parkway about 5 miles north. These arteries are also used to reach key destinations like George Bush Intercontinental Airport, Downtown Houston, the Port of Houston, Sugar Land, and more.

Date on Market:

2025-06-10

Houston Office for Lease - Galleria/Uptown

Sage Park Office Building at 2121 Sage Road presents a cost-effective opportunity for businesses to work out of a high-quality office with unmatched access in the desirable Uptown/Galleria neighborhood. The property features landscaped grounds that lead into the stunning three-story atrium lobby adorned with indoor greenery shining from the natural light that pours in from skylights and floor-to-ceiling windows. Tenants enjoy peace of mind with controlled key card building access and on-site property management, engineering/maintenance, and security. The ownership group built Sage Park Office Building and has managed it for 50 years with a current occupancy rate of around 90%, underpinning the care and satisfaction tenants can expect. Constant upgrades have been made, and a new roof and modernized elevators are on the way. There are over 600 parking spaces across the surface lot and the underground parking garage. Visitors can park here for free, adding another accessibility advantage to the convenient location. Seamless access is one of the biggest advantages of Sage Park Office Building. Interstate 10, Southwest Freeway, and Loop 610, three of Houston’s most important arteries, are accessible in 10 minutes or less, connecting drivers to all reaches of the metro. Closer in, thoroughfares like Sage Road, San Felipe Street, Westheimer Road, and Post Oak Boulevard provide exacting points of ingress and egress to further minimize traffic hold-ups. Abundant amenities abound in Uptown/Galleria, a neighborhood that blends the relaxed pace of the suburbs with the glitz and energy of the urban environment. One of the area’s most famous attractions is The Galleria, just a two-minute drive or 10-minute walk that offers world-class shopping with more than 375 stores, 30 restaurants, hotels, and more. Nearby, a thriving dining and entertainment district supplies the neighborhood with an eclectic variety of attractions. Despite these superior on-site and locational advantages, Sage Park Office Building is listed at an affordable rate with minimal fees on a modified gross lease. Inquire now to learn more.

Date on Market:

2025-12-08

Houston Office/Medical, Medical for Lease - Greenway Plaza

3100 Weslayan is a premier, four-story medical office building located in the heart of Greenway Plaza, offering an array of move-in-ready suites with free initial test fits. This property features an Energy Star rating, beautiful courtyards and patios, a day porter, on-site security with 24-hour monitored surveillance, Parks Pantry Market, and free garage parking. 3100 Weslayan’s spaces include all the medical essentials such as exam rooms, reception areas, nurse’s stations, file storage, lab space, and more. Tenants have peace of mind with professional ownership and management to curate a top-notch experience for their organization. This building has easy accessibility to several major freeways in the metroplex, including Highway 59 and Loop 610. 3100 Weslayan is also located near several high-end restaurants, hotels, and shopping, including The Galleria, Highland Village, and Rice Village. It is among a grouping of high-end neighborhoods, including River Oaks and West University Place. The building offers access to a well-educated labor pool as 71% of the population within a 3-mile radius has a bachelor’s degree or higher. The communities also provide a nearby clientele base as they tend to prioritize health and wellness. Commuters can reach Downtown Houston in about 15 minutes, and Sugar Land is 15 miles away, making this easily accessible for thousands of professionals throughout the metro.

Date on Market:

2025-12-17

Houston Office, Office/Medical for Lease - Southwest Beltway 8

Centre One is a premier office tower on Beltway 8 outside Downtown Houston. The impeccably maintained building features manicured green space, leading to an impressive two-story glass curtain wall at the entrance to the lobby. Desirable on-site amenities include a full-service deli, security, a multi-level parking deck, and dedicated property management and maintenance. Individual offices and full floors are available, allowing customization to suit the needs of any business. Centre One is a five-minute drive from Interstate 69 and a 30-minute drive from the city center. The property is only a five-minute walk from the Westwood Park and Ride, which provides bus services to downtown. Centre One boasts a sought-after location in the heart of Westwood, a diverse residential district with over 8,000 homes within a 1-mile radius. Talented professionals from affluent enclaves like Sugar Land, Rosenberg, Quail Valley, and Cinco Ranch can easily commute to this office. A well-maintained and amenity-rich property with incredible accessibility, Centre One is the ideal office destination.

Date on Market:

2025-02-18

Houston Medical for Lease - Northwest Far

7272 N Shepherd Drive is the premier opportunity for practices to establish themselves in a rapidly evolving area with a steeply increasing population and personal incomes. The freestanding building spans approximately 5274 square feet with an efficient layout fully organized for medical/surgery/dental or oral surgery practices and more. The former occupant is expanding into a large adjacent ambulatory surgical center (ASC), leaving it in operation-ready condition. 7272 N Shepherd Drive features doctors’ offices, exam rooms, plumbed for medical gas (Oxygen), operating rooms, procedure prep areas, a built-out nurses' station, records storage, clean work areas, a conference room, a reception desk, a waiting area, space for lab equipment, and more. It also has two radiation-safe procedure/operating rooms, making this an easy takeover for breast cancer centers, orthopedics, sports medicine, dental or oral surgery and more. Access is easy with ample parking, wheelchair-accessible entry, and a separate ambulance entrance. Pavement maintenance, parking power wash and restriping and repainting underway. The landlord has made recent upgrades, such as repainting and replacing fencing, power wash restriping of parking areas, paving repair and 7272 N Shepherd Drive’s robust infrastructure readies it for intensive operations. It includes two new full-capacity HVAC units and another smaller unit, extensive plumbing for users such as dental practices, and oxygen for medical usage, and a retention pond that has prevented flooding during several major storms. The annual lease rate is $15 per square foot with another $8.75 per square foot NNN (estimated tax, insurance, and CAM expenses). The landlord will also consider a lower lease rate per square foot depending on lease start, duration of lease, and build-outs/modifications. Located in a private area next to a courthouse and police station, 7272 N Shepherd Drive offers a safe, secluded location yet still provides maximum exposure along the heavily traveled thoroughfare with tower signage directly off the street. N Shepherd Drive is a four-lane road that leads directly to the center of Houston, providing visibility to about 30,000 vehicles per day, and Interstate 45 is only a half-mile away, enhancing accessibility. Kindred Healthcare has a large footprint in the immediate vicinity, already making this a go-to medical destination. As an established area for healthcare needs, 7272 N Shepherd Drive is a valuable address to serve the gentrifying environment, a trend that is immediately visible from the building’s doorstep, with new condo buildings popping up around it. In fact, the number of households within a 2-mile radius grew by 8.8% from 2020 to 2024 and is estimated to rise another 8% through 2029. The current demographic landscape already has a high prevalence of kidney disease and diabetes, and the dynamic changes happening in the area will increase demand for even more specialties.

Property Type:

Office

Date on Market:

2025-05-12

Houston Office, Flex for Lease - Westchase

Westchase Corporate Park is strategically positioned in the heart of the Westchase District on Richmond Avenue. This 13-building office and industrial campus offers tenants immediate access to Beltway 8 and the Westpark Tollway, ensuring excellent connectivity for businesses. The property features a variety of flexible suites designed for both corporate office and industrial warehouse users, providing numerous layouts. With surface-level parking and a locally owned and managed approach, Westchase Corporate Park focuses on fostering long-term relationships and tenant satisfaction.

Date on Market:

2025-12-16

Houston Industrial for Lease - FM 1960/Champions

Located in the Willowbrook/Cypress submarket, Theall Business Park comprises a total of 10 buildings. Managed by Fort Management, this park is ideal for businesses in manufacturing, automotive services, construction, and other industrial sectors. Each suite at Theall Business Park is equipped with essential amenities to support business operations. These amenities include an 18-foot clear height, climate-controlled warehouses, 14 x 14-foot grade-level loading doors, a fenced and gated area for security, and access to 3-phase power. 6743 Theall Road boasts prime regional connectivity, with the main hubs of the Texas Triangle (Houston, San Antonio, Dallas, Fort Worth, and Austin) all accessible within 250 miles or less. Key routes surround the site, including Highway 249, Beltway 8, and Interstate 45, ensuring seamless access for optimal operational efficiency. Theall Business Park also has a strong employee pool at its disposal, with over 190,000 employees working in blue-collar industries (such as construction and manufacturing) within a 10-mile radius. Along with the strong logistical positioning, tenants at Theall Business Park have access to various amenities, including the Willowbrook Mall, just a 1.5-mile drive away. With prime connectivity, versatile spaces, and a deep local talent pool, Theall Business Park delivers an exceptional opportunity for industrial growth and efficiency for any business.

Date on Market:

2025-10-01

Houston Office/Medical, Retail for Lease - Southwest Beltway 8

The West Oaks Plaza is conveniently located at the corner of Westheimer Rd. and Richmond Ave, attracting heavy day time foot-traffic. The building shares a parking lot with the redeveloped West Oaks Mall and includes several curb-cuts for easy access. The plaza is surrounded by the communities of Mission Bend, Eldridge Parkway, and the Energy Corridor. Located across from the plaza is the beautiful George Bush Park. The plaza is currently occupied by a wide range of amazing, long-time, happy tenants because we do our own property management!

Date on Market:

2025-12-16

Houston Office for Lease - Midtown

2000 Crawford St, formerly known as the St. Joseph Professional Building, consists of 135,586 square feet of office space in Houston. This iconic 18-story building offers excellent visibility and access as the property is situated near major highways including I-45, US-59, and I-10. 2000 Crawford is located on the Metro bus line with the MetroRail just 5 blocks away. A newly renovated tunnel can be accessed, connecting 2000 Crawford to the St. Joseph Hospital campus located across the highway. Valet and surface parking available.

Date on Market:

2025-11-21

Bellaire Office/Medical for Lease

On campus medical office building in the Bellaire/Galleria Area.

Property Type:

Office

Date on Market:

2025-06-12

Houston Flex for Lease - South Main/Medical Center

This 5,369 SF office space in Suite 900 features a large ISO Level 7 Clean Room and is located in the heart of the Texas Technology Park. The space is fully built-out and ready for immediate occupancy, offering 13 private offices, a reception area, coded entry, R&D/open work areas, two conference rooms, a break room, server room, utility closet, dock/storage area, and restrooms. High ceilings, natural light, and ample parking further enhance the workspace. This suite is well-suited for companies requiring both office and light industrial capabilities in a strategic Houston location. Please contact the listing agent for rental rate and additional details.

Date on Market:

2025-11-06

Houston Flex for Lease - Greenspoint/N Belt West

Date on Market:

2025-09-15

Bellaire Flex for Lease

2,100 SF of flexible space with a private entrance in a prestigious Bellaire location. The suite is built out as a 2nd generation medical lab, offering a turnkey opportunity for medical, office, or specialized users seeking a high-quality space in a prime area.

Property Type:

Office

Date on Market:

2025-08-27

Houston Flex for Lease - South Main/Medical Center

Date on Market:

2025-07-31

Houston Flex for Lease - FM 1960/I-45 North

• T5 lights • 20' eave height • 3 phase, 480V, 200 amps • 12'x14' grade level doors (2) • Fiber internet available through Comcast (1,000 mbps) • Has existing wiring for cameras • Data/server room

Date on Market:

2025-02-03

Houston Office/Medical for Lease - Katy Freeway East

Close proximity to Memorial City Mall and Memorial Hermann Hospital Complex.

Property Type:

Flex

Date on Market:

2023-12-27

Houston Medical for Lease - FM 1960/Hwy 249

Time-share office for sublease, flexible time schedule and space leased up to 5 exam rooms. Current tenant (Dr. Allen Chu) only work part-time in this office three mornings per week at this location. Other than that three morning, the entire office is available for sublease. Lease rate will be the same as the tenant's lease rate which is approximately $36 per SF (base rent and operational cost). Private class A medical professional building within the medial campus of the Houston Methodist Willowbrook Hospital. The Building is right across the Hargrove street from the Hospital and has its own private parking. Hospital cafeteria for patients and doctor lounge for physicians are easily accessible. Recently newly renovated, 5 exam rooms, waiting area with TV, kitchen, two physician offices, IT room with internet connections. Current lease holder has the lease through September 2028, with renewal option for two 3-year consecutive terms until 2034. right next to Hospital campus, Location, Fully rented very busy class A medical professional

Property Type:

Office

Date on Market:

2023-10-10

Webster Office/Medical, Medical for Lease - NASA/Clear Lake

202 North Texas Avenue in Webster is a 21,000 sf professional medical office project located in the heart of the Clear Lake Medical Center. The site is located directly across from Houston Physicians' Hospital and in close proximity to Clear Lake Regional, Kindred Hospital, UTMB Clear Lake Campus and several other hospitals and medical providers. The property offers monument and fascia signage, ample parking, and easy access to the Gulf Freeway and all of Clear Lake's most heavily traveled roadways.

Date on Market:

2024-11-12

Houston Flex for Lease - Greenspoint/IAH

Three free standing flex buildings located in North Houston.

Date on Market:

2023-07-03

Houston Office for Lease - North Loop West

7155 Old Katy Road is a boutique office building with two spacious & bright lobbies, natural light and well-maintained grounds. The building offers easy access and parking, and is at the doorstep of the Heights and Memorial Park. The property is secured with security cameras and gated entrances, and offers ample parking for staff and visitors. Tenants and visitors enjoy a 24-hour self-serve café and furnished exterior courtyard for lunch or breaks. The property is conveniently located a few minutes from the Galleria with easy access to major freeways (Katy Fwy, the West Loop, and US 290).

Date on Market:

2025-07-24

Houston Multiple Space Uses for Lease - South Main/Medical Center

* One building covers entire address range

Date on Market:

2025-07-31

Humble Office/Medical for Lease - Northeast Outlier

Property Type:

Office

Date on Market:

2024-08-29

Houston Office for Lease - West Belt

Date on Market:

2024-08-07