45 Life Science Properties for Lease in Houston, TX, USA

Houston Office/Medical, Flex for Lease - South Main/Medical Center

Texas Technology Park is a state-of-the-art Industrial Business Park built in 6 phases consisting of 16 buildings totaling 759,861 SF on 68 acres. The cutting-edge property is located minutes from the Texas Medical Center, with easy access to Loop 610 and Highway 288.

Date on Market:

2025-07-23

Spring Office, Office/Medical for Lease - FM 1960/Champions

Nestled against the tree-laden Cypress Creek, Klein Creek Plaza presents the opportunity to set up operations in Spring, Texas’s premier office building and take advantage of its superior connectivity without the cost and congestion of its Downtown Houston counterparts. Klein Creek Plaza offers peak flexibility with individual executive suites or large multi-office spaces. Choose a move-in-ready space and get started right away, or work with CIVET Real Estate’s expert management team to customize a suite perfectly tailored to maximize organizational success. Klein Creek Plaza gleams with elegance. It features a well-appointed entry, digital lobby directory, and floor-to-ceiling windows overlooking the pond and green space, a rare luxury in its suburbanized location. Located just 30 minutes north of Downtown Houston, the area has become a premier destination for commuters, fostering an amenity-rich environment so employees can embrace a modern live-work lifestyle. With median home values within a five-mile radius more than $100,000 lower than the national figure, employees can afford to stay close to the office while being a stone’s throw from Houston’s vibrant nightlife. After work, they can unwind over a cocktail at Tilted Glass Tavern or enjoy Mexican cuisine at Taqueria Los 2 Carnales, a short walk from the office. Those on the go can knock out their errands or get a bite to eat at the Kroger, 24 Hour Fitness, Starbucks, and dozens of eateries five minutes away before taking off on nearby Interstate 45. Not only is Klein Creek Plaza positioned in an idyllic employee environment, but its market is also red-hot and provides a plethora of organizational advantages. The Northwest Medical Center is just over three miles away, making this an ideal launching point for health care support services or local practices. The median household income of $67,104 and age of 35.2, with 30% of those holding a bachelor’s degree or higher in a five-mile radius provides a well-educated yet affordable labor pool of young professionals. As outstanding employment opportunities drew people to the market, the number of households in a 10-mile radius rose by 71,800 from 2010 to 2022, a number that is expected to increase by 22,600 by 2027, ensuring a robust workforce for years to come. Of course, the swell of demand has brought higher office rents. Klein Creek Plaza’s rates are well below the Houston market’s average of around $28 per SF. Combined with best-in-class spaces and unbeatable accessibility, this is an excellent, affordable alternative that doesn't sacrifice the advantages of a modern office.

Date on Market:

2024-02-15

Houston Office/Medical for Lease - South Main/Medical Center

Previously built-out and utilized by major institution, requiring highest standard of maintenance on all building systems. Secured fence with remote access. Fully sprinklered. Zone X - area determined to be outside of the 0.2% annual chance floodplain. Superb location on light rail (near NRG rail stop), across from NRG Stadium and immediately south of central TMC.

Property Type:

Office

Date on Market:

2024-11-01

Houston Multiple Space Uses for Lease - South Main/Medical Center

*Medical Office Building *6 Stories *Part of 21-Acre Medical Campus *On-site Management *Ample parking in adjacent parking facility *Campus Deli *Valet Parking Available At the Texas Medical Center across from The Woman's Hospital of Texas

Date on Market:

2024-12-30

Houston Office for Lease - Midtown

The Arc offers 28,000–31,000 SF flexible floor plates within a 196,400 SF building featuring 15-foot floor-to-floor heights—ideal for both lab and office users. The infrastructure is fully future-proofed, with dedicated lab exhaust and make-up air risers, a robust chilled-water system supported by dual 300-ton air-cooled chillers, neutralization systems, emergency power capacity, and freight/loading accommodations to support growth and specialized equipment. Electrical capacity reaches 20 W/SF for lab and 6 W/SF for office, with HVAC designed at 1.2 CFM/SF.

Date on Market:

2025-10-15

Houston Medical for Lease - South Main/Medical Center

Medical office in Houston’s South Main/ Medical Center/ Third-Ward. Previous tenant was a primary care, specialty care, and urgent care medical provider, catering to patients of all ages. Currently configured with 14 patient examination rooms, radiology room, large reception and intake area, well appointed/ functional nurses stations, and staff break area.

Property Type:

Office

Date on Market:

2025-09-09

Houston Flex for Lease - South Main/Medical Center

Lakes at 610 Service Center 2525 W Bellfort Blvd

Date on Market:

2025-10-17

Houston Industrial for Lease - Southwest/Hillcroft

- Grade-Level Loading - Paved Outside Storage Component - Fully Fenced and Gated - ±100 Parking Spaces - 3 Phase, 480 Volts - ±16’ - ±24’ Clear Height - Utilities: City of Houston - Quick Access to Southwest Fwy, Westpark Tollway, & 610 - Landlord will lease buildings separately

Date on Market:

2025-02-19

Houston Office/Medical, Medical for Lease - South Main/Medical Center

134,910 SF, Class A Medical Outpatient Building on the south side of the Texas Medical Center.

Date on Market:

2024-01-18

Houston Office for Lease - Katy Freeway East

Flex/Office Space Available For Lease

Date on Market:

2024-08-26

Houston Office, Office/Medical for Lease - Westchase

The Westchase District provides easy access to four major highways, making it Houston’s most accessible commercial district. At 3030 S Gessner, you can lease premium office, medical space, and lab space ensuring minimal commute times and maximum convenience.

Date on Market:

2025-10-15

Houston Industrial for Lease - Northeast Near

BioHub Two’s master plan is comprised of over 500,000 square feet for cGMP manufacturing, wet and dry labs, and office space located in Generation Park, with nearly $30 million in infrastructure nearing completion to serve the new site. Generation Park is one of the world’s largest privately held commercial developments in the country’s most diverse city, Houston, TX. You’ll be surrounded by forward thinking companies and have direct access to workforce training programs at San Jacinto College and Lone Star College. BioHub Two’s 45-acres can be subdivided to accommodate the full spectrum of life science uses including small and large-scale pharmaceutical and medical device manufacturing needs. Adjacent to the BioHub sites are plans for two multi-family communities and The Commons, a 5-acre green space with freestanding opportunities for small-format restaurants and cafes. Future tenants will have direct access to workforce training programs at San Jacinto College and Lone Star College. Employees and guests will be linked to retail amenities and beautiful parks via The Ray, a looping pedestrian superhighway that connects all of Generation Park West. BioHub Two neighbors San Jacinto College’s Center for Biotechnology at Generation Park, in partnership with the National Institute of Biotechnology Research and Training (NIBRT). NIBRT is globally recognized as the gold standard in training and research solutions for the biopharmaceutical manufacturing industry. San Jacinto College, nationally recognized as one of the country’s best community colleges, will open a brand-new Center for Biotechnology at San Jacinto College’s Generation Park campus in Q1 2025. This state-of-the-art facility will provide comprehensive, hands-on training with realistic good manufacturing practices (GMP) simulated environments and offer an associate of applied science degree in biomanufacturing technology, and shorter credentials for post-graduates, to meet workforce needs. A 2022 study from The Greater Houston Partnership identified Houston as a prime hub for cell and gene therapy R&D and manufacturing, cancer-focused molecular diagnostics within R&D and production, and biologics drug development and manufacturing. Houston has cultivated a fast-growing life science ecosystem: there are over 700 life science companies, a core life science workforce totaling 26,000, 5,000 active clinical trials and is ranked tenth in the Top 20 US Metros for Life Science Companies. Houston is ranked third in the US metro for business expansion and relocation and is included in the top 25 global cities of the future.

Date on Market:

2023-08-04

Houston Flex for Lease - South Main/Medical Center

Plaza del Oro is a flex space office park, consisting of 3 buildings (8275 El Rio, 8285 El Rio, and 900 S Loop West) located along the 610 Loop near Hwy 288. All spaces have grade level loading docks and climate control. Plaza del Oro is located in close proximity to the Texas Medical Center and is perfect for Medical, Life Science/Research, and general Office users.

Date on Market:

2025-12-16

Houston Industrial for Lease - Katy Freeway West

- Master planned environment - Premier Northwest location - Outstanding visibility and corporate identity - Excellent accessibility - Abundant parking that provides easy egress and ingress - Tilt-up concrete construction - All concrete paving - Professionally maintained landscaping - 24/7 Access - Cost effective alternative to full gross office space with no add on factor - Productive and exclusive working environment with ability to control HVAC and electrical usage

Property Type:

Flex

Date on Market:

2025-11-17

Houston Flex for Lease - Northeast Near

Life science has a bright future in this planned Cell and Gene Therapy cGMP Manufacturing Facility located in Generation Park in northeast Houston. Located near Beltway 8 and all of Houston's interstates (I-69, I-45, and I-10) this cGMP bio manufacturing facility is only 15 minutes from IAH Airport and 30 minutes from the Texas Medical Center (TMC). This logistical advantage provides global access for both people and product, as well as being near the largest patient population on the planet, ideal for cell and gene therapy organizations. Unique to Generation Park and this biopharma facility on a national scale is the recently announced San Jacinto College Biotech Training Center that is adjacent to the property. At this biotech training center companies will find an abundance of well trained talent for their operations. Generation Park makes attracting and retaining talent a breeze with the growing trail network that connects every property throughout the development, quality homes and apartments in a wide range of price points, and fantastic schools.

Date on Market:

2021-07-16

Houston Office/Medical for Lease - South Main/Medical Center

Adjacent to the Texas Medical Center, Levit Green’s 53-acre district will offer a new level of life science product never before seen in Houston. Together with award-winning architect, HOK, the 5-story, 290,000 SF Phase I building is designed from the inside out to best serve the science of the most discerning tenants.

Property Type:

Office

Date on Market:

2023-09-06

Houston Multiple Space Uses for Lease - South Main/Medical Center

What was once a Nabisco cookie factory now drives TMC’s diverse alliance of early-stage innovators. The TMC Innovation Factory empowers entrepreneurs from across the world to push the limits of discovery and bring their solutions to life faster with the support of industry partners, TMCi programming, and the greater TMC ecosystem.

Date on Market:

2025-09-26

Houston Office, Office/Medical for Lease - FM 1960/Hwy 249

Medical Arts I is a Class A medical office building located at 20207 Chasewood Park Drive and connected to St. Luke's Health – The Vintage Hospital via a covered walkway. Medical Arts I features a covered patient drop-off, on-site management, and trail access to unwind around the campus pond. The spaces have yet to be built out, allowing for plenty of agency over the design of the medical office. Tenants can also take advantage of the expertise of Transwestern and the renowned medical property manager and owner, Welltower, to turnkey the space or provide tenant improvement allowances with creative deal structures. With the St. Luke's Hospital next door and Houston Methodist Willowbrook Hospital, the Heart Care Center of Northwest Houston, UT Physicians at Vintage Park, a Kelsey-Seabold Clinic, and much more within three miles, this is one of the most concentrated healthcare zones in the Northwest Houston submarket. This not only provides a convenient stop for clients in need of multi-speciality care but also fosters a synergetic community of referring physicians. The locale also provides an excellent payer mix as Texas is in the country's Top 10 of the percentage of self-paying patients. Demographics indicate this submarket is above the state norm, with an average household income of $108,441 within a five-mile radius. Many high-profile, affluent neighborhoods like Majestic Oaks, Estates at Windrush, Champions, and the upscale shopping destination Vintage Park are within five minutes of Medical Arts I.

Date on Market:

2025-08-17

Houston Coworking for Lease - Midtown

2000 Crawford is a 135,000+ square foot office building located in Houston`s growing Midtown, just outside Houston`s Central Business District. This iconic 18 story building offers excellent visibility as the property is situated near the US-59 and I-45 intersection with easy access to all major highways and freeways. The property is located on the Metro bus line with the MetroRail just 5 blocks away. Tenants and visitors alike can conveniently travel to and from the St. Joseph Hospital via a tunnel that connects the two buildings.

Property Type:

Office

Date on Market:

2025-11-21

Houston Office/Medical for Lease - South Main/Medical Center

2nd-generation lab space. Back-up generator. Out of all floodplains. 2016 renovated building. Energy efficient LED lighting. South Texas Medical Center adjacent to former Astroworld site.

Property Type:

Office

Date on Market:

2024-01-10

Houston Medical for Lease - South

Property Type:

Retail

Date on Market:

2024-09-24