102 Life Science Properties for Lease in Pennsylvania, USA

Norristown Office, Flex for Lease - Norristown/Valley Forge

Date on Market:

2024-09-10

Plymouth Meeting Flex for Lease - Plymouth Mtg/Blue Bell

Located at the key regional interchange of I-476 (Blue Route & NE Extension) and I-276 (PA Turnpike) and minutes from I-76 (Schuylkill Expressway) and Rt 202. Excellent visibility from Blue Route (I-476) and PA Turnpike (I-276). 100% climate-controlled flex / industrial space with new tailgate and drive-in loading docks. Office space built to suit. 16’4" clear height. Light industrial zoning, allows lab/ R&D, manufacturing, warehouse. Abundant amenities nearby including Plymouth Meeting Mall (Whole Foods, PF Chang's, Redstone Grill), two hotels in walking distance, restaurants, and Metroplex Shopping Center (Target, Giant, Best Buy, Starbucks). Existing tenants include Donnelly's HVAC and Globus Medical.

Date on Market:

2024-03-11

Trevose Industrial for Lease - Lower Bucks County

Located in the Metropolitan Business Center, this 118,000-square-foot industrial distribution property is convenient to Route 1, PA Turnpike & Interstate 95.

Date on Market:

2025-11-21

Ambler Office, Flex for Lease - Ft Wash/Spring House

Spring House Innovation Park, or 'SHIP', is Greater Philadelphia's premier research and development focused business park with over 600,000 SF of planned or existing laboratory and office space across 130+ acres with the capabilities of accommodating requirements ranging from a few hundred square feet of startup/incubation space to over 100,000 SF. There is additional land within SHIP which can accommodate small to large custom build-to-suit requirements as well. Aside from Class A R&D space, many amenities are planned at SHIP including a campus food service/conference center building, indoor/outdoor fitness, a walking trail throughout the campus, and outdoor seating and meeting areas. Tenants can take advantage of a knowledge community at SHIP which ranges from some of the newest companies up to the largest and most established institutions in the world.

Date on Market:

2025-08-28

Philadelphia Multiple Space Uses for Lease - University City

3440 Market Street is a six-story (6-story), 120,000-square-foot state-of-the- art wet and dry laboratory facility. This ?exible ?oorplate provides users with 10’ ?nished ceilings, the ability to plan their layout ef?ciently and an impressive window line for great natural light throughout. The building is designed to accommodate typical of?ce, clinical and lab uses. The 19,600 RSF ?oor plates, 14.8’ slab-to-slab - 10’ ?nished ceiling heights maximizes the amount of natural light throughout the structure. 3440 Market Street incorporates many energy saving features, state-of-the-art systems, sustainable design and construction practices, has ?ve levels of parking (500 spaces), and substantial city and state tax (KIZ/KOZ) bene?ts available. The building will incorporate many energy saving features, state-of-the-art systems, and sustainable design and construction practices. The building is designed to accommodate typical of?ce, clinical and lab uses.

Date on Market:

2025-10-23

Canonsburg Office, Flex for Lease - Washington County

The Stealth Technology Center at 333 Technology Drive is a newly renovated office building with ample on-site amenities that help office, tech-flex, R&D, and any other tenants needing lab space recruit and retain top talent. This four-story, ±116,000 square-foot office tower is under new ownership, new management, and new improvements completed in 2020 include new common area restrooms, signage, landscaping, and a new roof. Additionally, newly added, tenant-focused amenities include a lounge with a putting green, corn hole boards, foosball tables, ping pong tables, a balcony, and vending machines, and an outdoor patio with picnic tables and umbrellas. Tenants also enjoy an on-site café, 24/7 suite access, second-floor balconies in select suites, energy-efficient reflective glass that cuts heat rays by 50%, architectural glass window features, and options for Comcast, Verizon, DQE, and Fibernet connectivity. Stealth Technology Center is home to the Health Club at Southpointe, providing a full-service fitness facility complete with group classes, personal training, complimentary towels, locker rooms, childcare, and corporate rates. Free Health Club memberships are offered with new leases. Current availabilities include a range of Class A office suites with 10’ finished ceiling heights, loading dock and drive-in access, a warehouse with 16’ ceilings, and options for furniture. Employees enjoy abundant parking, at a ratio of 5 per 1,000 square feet, and easy access to I-79, which conveniently connects to the Pittsburgh International Airport and Downtown Pittsburgh.

Date on Market:

2025-11-18

Horsham Township Flex for Lease - Horsham/Willow Grove

• Recently renovated GMP/R&D building • Located in the Keystone Innovation Zone (KIZ). • No gross receipts tax in Horsham Township • Building features include: 1. Power: (2) 2000AMP, 480/277, 3 phase services 2. (5) New loading docks 3. New 4” Domestic water service entering building 4. New gas service to building with sufficient capacity for typical lab tenant—will support 100% OA heating 5. 18’6” clear height 6. Interior demo

Date on Market:

2018-08-30

Pittsburgh Office for Lease - Oakland

Nestled in the heart of Pittsburgh’s Technology Center overlooking the riverfront views of Downtown and Southside Marina. The Riviera is the perfect location for your luxury wet lab, biotech, and office space. With a two-building 310,000 square foot campus there is plenty of room to grow. Sustainably managed by Class-G, the property includes several amenities such as onsite fitness center, DeFer Coffee and Tea, conference center, outdoor patio and eating areas, options for expansion, and flexible floor plans. Enjoy the five-minute commute and riverfront views of Downtown Pittsburgh. Transportation has been made easy with onsite parking, corporate bike share, multiple bus lines at onsite bus stop, and a private shuttle to Southside Works restaurants, retail and housing.

Date on Market:

2025-04-09

Philadelphia Office for Lease - University City

3535 Market Street is an 18-story, Class-A office/Medical building located in downtown Philadelphia. It has terrific views of the city, continuous glass lines, large floor plates, and easy access to public transportation. Prominent location in the heart of the University City Science Center with proximity to the University of Pennsylvania, Drexel University, and Children's Hospital of Philadelphia

Date on Market:

2025-01-31

Philadelphia Office/Medical for Lease - University City

Proposed 400,000Sf office building.

Property Type:

Office

Date on Market:

2017-06-26

Philadelphia Office for Lease - University City

3624 Market Street is a five story lab office building centrally located in the heart of uCity Square. The building has GMP, R&D laboratory space and office space. uCity Square is rich in amenities. uCity Square tenants benefit from a vibrant tech, medical device and life science ecosystem adjacent to major academic and research institutions including the University of Pennsylvania, Drexel University, Penn Medicine, the Children’s Hospital of Philadelphia, Wistar Institute and Monel Chemical Senses Center. 3624 is located in a Keystone Innovation Zone.

Date on Market:

2025-03-13

Philadelphia Coworking for Lease - Delaware County

International Plaza I is a 6-story, Class-A, office building consisting of 194,411 sf. Premier location adjacent to Philadelphia International Airport with complimentary shuttle service to airport and City Center train depot with link to Center City and SEPTA bus service.The building features include: fiber optic served; all new HVAC - elevators and mechanical systems; and completely refurnished restrooms. It also offers a corporate lunchroom seating 400 people, ample free parking, 24-hour manned interior & exterior security, spacious and modern corporate dining facility, beautifully landscaped grounds, and interior and exterior security.The building features include: 24/7 Building Access, Free Airport Parking and Shuttle for Tenants, Philadelphia Address, Banking, Convenience Store, Food Service, On Site Management, Property Manager on Site, Security System, Barber Shop/Hair Salon, Conference Rooms

Property Type:

Office

Date on Market:

2014-02-19

Philadelphia Office for Lease - University City

One uCity Square is a premier Class A lab and office tower rising 13 stories in the heart of Philadelphia’s University City, a nationally recognized innovation district. Delivered in Q3 2022, this ±400,000 SF trophy asset is part of the transformative 7.7 million SF uCity Square mixed-use development, which integrates life sciences, academic institutions, and entrepreneurial energy into a walkable, transit-rich ecosystem. Tenants will benefit from a dynamic work environment designed to attract top-tier talent. The building features 15-foot slab-to-slab heights, 32K SF floor plates, private outdoor terraces, and panoramic views of Center City and Fairmount Park. It is the only building in Philadelphia to offer 100% outside air, bipolar ionization in common areas, and MERV 14 filtration—delivering air quality nearly double that of typical commercial buildings. One uCity Square is located within both a Keystone Opportunity Zone and a Federal Opportunity Zone, and qualifies for a 10-year real estate tax abatement, offering substantial financial advantages. The site is adjacent to institutions such as Penn Medicine, Drexel University, and CHOP, and is served by multiple transit options including Amtrak, regional rail, subway, and trolleys. The surrounding uCity Square community includes ground-floor retail, activated plazas, and curated programming such as Venture Café events and outdoor wellness activities. Tenants also enjoy hospitality-inspired lobbies, structured parking, indoor bike storage, and contactless entry from street to suite.

Date on Market:

2025-09-29

Philadelphia Coworking for Lease - University City

Enviable connectivity with a riverside location, this landmark location in University City is ideal for businesses that want to make this city their own. The CIRA Center Office Space has a direct connection to Amtrak’s 30th Street Station, so it’s convenient for commuters and business travel. This striking building with a strong presence in Philadelphia’s skyline offers a rooftop park - the perfect place to relax and make plans between meetings. Step outside to explore downtown Philadelphia or take in the views of the Schuylkill River.

Property Type:

Office

Date on Market:

2023-06-15

Newtown Coworking for Lease - Lower Bucks County

The Silver Lake Executive Campus consists of 35 acres and has a site capacity for 325,000 square feet of exceptional quality mid-rise office space.* Less than 1 mile from the Newtown/Yardley interchange of I-95 in Newtown Township, Bucks County.* Extensive frontage on, and direct access to, the Newtown Bypass (Rt 413).* Build-to-suit sites available. Silver Lake Rd & Rt 332

Property Type:

Office

Date on Market:

2007-04-18

Philadelphia Office for Lease - University City

Date on Market:

2007-07-17

Philadelphia Office for Lease - University City

Class A office building offering office, lab and R&D space.This building is in a Keystone Opportunity Zone (KOZ). The glass and steel 17 story tower will be a landmark structure on the southwest corner of 34th & Market Streets. From its' upper floors the building will offer impressive views in all directions. It will be the first impressive tower that many visitors to the Science center will see as they approach. The University of Pennsylvania, The Children's Hospital of Philadelphia, Drexel University, and The Wistar Institute are all in close proximity to the site.

Date on Market:

2007-07-19

Exton Office/Medical for Lease - Exton/Whitelands

Eagleview is a live work play community, consisting of 800 acres, located on Route 100 at the Downingtown Interchange (Exit 312) of the PA Turnpike. Eagleview provides the highest quality office, R & D, manufacturing, retail and residential accommodations to over 10,000 people. 665 Stockton is located one block from Eagleview Town Center amenities; On-site amenities: The Brickside Grille, Suburban Beer Garden, Al Pastor Mexican Restaurant, Bluefin Sushi, Gemini Hair Design & Spa, Wellington Square Book Shop, Persis Indian Grill, Rita's Water Ice, Good Life Organic Kitchen, Twin Valley Coffee, Good Girls Bakery and acac Fitness Center are located at the Town Center. Ideally situated on Route 100 at the Downingtown Interchange (Exit 312) of the PA Turnpike.

Property Type:

Office

Date on Market:

2019-07-02

Philadelphia Office for Lease - University City

3020 Market Street is a LEED - SILVER certified boutique office building and tax abatement property well-positioned in the University City District's thriving research and technology corridor. Situated one block from Philadelphia's 30th Street Station, the building's prime location provides its tenants with a wide range of conveniences and amenities, such as access to Penn Park, Indego (Philly Bike Share) stations, the Schuylkill River Boardwalk and the popular food truck lineup at The Porch at 30th Street Station.

Date on Market:

2025-02-12

Levittown Flex for Lease - Lower Bucks County

Modern, free-standing, one-story, industrial facility. Currently demised into three (3) 5,000 square foot units. Unit B currently available. Ideal for a lab/hi-tech user. Landlord will air-condition the space and complete all improvements to suit.

Date on Market:

2024-05-01

Exton Office for Lease - Exton/Whitelands

Date on Market:

2022-09-28

Chadds Ford Flex for Lease - Delaware County

Date on Market:

2025-11-19

Philadelphia Office for Lease - Navy Yard

4751 League Island Blvd presents a rare sublease opportunity within Philadelphia’s thriving Navy Yard innovation district. Purpose-built for biotech and advanced therapeutics, this facility offers up to 82,000 SF of flexible space, including ISO-7 and ISO-8 cleanrooms, support labs, cold storage, and warehousing. The building is engineered for speed-to-market and operational efficiency, with robust utility infrastructure including compressed air, CO2, N2, and backup power systems. Tenants benefit from seamless integration of office, R&D, and manufacturing areas, with options for dedicated entrances and future expansion. The site is part of a 400,000 SF manufacturing campus adjacent to CDMO and testing services, supporting the full lifecycle of life science operations. Located just minutes from Philadelphia International Airport, University City, and Center City, the Navy Yard offers unmatched accessibility and lifestyle amenities. With over 20 acres of parks, waterfront trails, and on-site dining, this vibrant ecosystem attracts top talent and fosters innovation. The sublease runs through 2037, providing long-term stability in a premier location.

Property Type:

Flex

Date on Market:

2025-10-23

Philadelphia Office for Lease - University City

Pennovation Center is an innovation hub with a variety of premium shared or private space options for innovators and researchers around the Tri-State area. Pennovation Center fosters a sense of community and encourages collaborative endeavors within the Pennovation Works, and regional innovation, ecosystem

Date on Market:

2024-02-20