33 Life Science Properties for Lease in San Jose, CA, USA

Milpitas Flex for Lease

Situated in Milpitas, 688 Gibraltar Court is a research and development manufacturing building that has recently undergone extensive renovations, ensuring a modern and efficient workspace for businesses. With a substantial 2,000-amp 277/480-volt power panel, it offers robust electrical support for manufacturing and research needs. The presence of a backup generator ensures uninterrupted operations even during power outages. Furthermore, the building features a convenient double-door platform and a grade-level door, facilitating easy access and efficient logistics. In the bustling industrial hub of Milpitas, 688 Gibraltar Court boasts excellent connectivity via easy access to Highway 237, Interstate 680, Interstate 880, and Calaveras Boulevard. The property is conveniently located within walking distance of the new BART Milpitas Station, ensuring a seamless commute for administrative staff. Nearby amenities, including Big O Tires, Chick-fil-A, Safeway, Panda Express, McDonald's, and Starbucks, offer a variety of dining and service options for those passing through. This strategic industrial location can reach a population of approximately 8.5 million people in major cities like San Jose, San Francisco, Fresno, Los Angeles, San Diego, and Las Vegas, all within a day's drive. With its modern upgrades, powerful infrastructure, and exceptional location near major transit routes and amenities, 688 Gibraltar Court stands out as a premier choice for businesses seeking a versatile and accessible R&D and manufacturing facility in Milpitas.

Date on Market:

2025-11-06

Milpitas Flex for Lease

Welcome to 1561 Buckeye Drive, a versatile commercial opportunity for businesses seeking a well-equipped facility for research and development (R&D), manufacturing, or light industrial operations. The 44,815-square-foot building spans a generous floor plan with expansive lab spaces designed for innovation and productivity. 1561 Buckeye Drive has a long list of key features that boost efficiency. This advantageous property boasts large, open-concept lab spaces, perfect for a variety of research and development activities. With ample room for workstations, equipment, and specialized setups, this space offers the flexibility needed for cutting-edge projects. The facility's strategically positioned roll-up doors provide easy access for deliveries and shipments, while multiple loading docks ensure smooth logistics operations. The property has modern amenities, including 16-foot, 8-inch ceilings and 2,000-amp, 120/480-volt, 3-phase heavy power. Finally, this site is zoned to accommodate a wide range of industrial and commercial uses. Strategically situated in the heart of Milpitas, California, 1561 Buckeye Drive benefits from its proximity to major highways, including Interstate 880, offering seamless access to Silicon Valley, transportation hubs, and the greater Bay Area. Whether a business is developing new technology, expanding operations, or creating custom products, 1561 Buckeye Drive provides the flexibility to meet needs.

Date on Market:

2025-01-08

Milpitas Flex for Lease

Spanning 82,540 square feet, 195 S Milpitas Boulevard is the premier opportunity to establish a presence at the heart of Silicon Valley. Formerly occupied by View Inc., a leading smart window manufacturer, this property is equipped with high-tech infrastructure, providing a make-ready solution for R&D or manufacturing needs. Some of the features include clean rooms, lab areas, office space, and 13,600 amp heavy industrial power. The surrounding area hosts leading companies such as Lumileds, Westrock, Logitech, Tesla, and Seagate. Proximity to these industry leaders allows businesses to tap into an established network of suppliers, manufacturers, and distributors, reducing transportation costs and supply lead times. With quick access to major highways like Interstate 880, Highway 237, and Interstate 680, the well-positioned property can reach key regional hubs, enabling efficient operations and logistics. Milpitas has a highly skilled industrial workforce, with about 150,000 professionals employed in manufacturing within a 10-mile radius. The area around 195 S Milpitas Boulevard is served by a variety of amenities that enhance the convenience and quality of life for employees and businesses. Nearby shopping centers like the Great Mall provide access to a range of dining options, retail stores, and services. Milpitas' central location ensures easy access to everyday essentials while being part of a thriving business district.

Date on Market:

2024-10-08

San Jose Office for Lease - South San Jose

Located at 6399 San Ignacio Avenue in San Jose, California, this premium Class A top-floor office space offers a rare opportunity to lease in one of Silicon Valley’s most sought-after commercial corridors. The property features a modern two-story office building totaling 41,831 square feet situated on a spacious ±2.5-acre site. Recently renovated in 2023, the building showcases a sleek design with huge windows that allow natural light to flow through, a welcoming lobby, and energy-efficient LED lighting. 6399 San Ignacio Avenue is fully occupied except for this available second-floor suite. The first floor is leased to a premier hospital medical office tenant undergoing new buildouts scheduled for April 2026. The second floor is home to a semiconductor design company, a marketing agency, and a software firm, creating a professional environment. Tenants will enjoy ample on-site parking with 134 ADA-compliant surface spaces, suite door signage, and lobby directory signage for enhanced visibility. Strategically positioned at the corner of San Ignacio and Santa Teresa, the property offers excellent accessibility. Located one block from the Light Rail station, you’ll enjoy easy access to Highways 85 and 101, creating a reverse commute. The building is approximately 15 minutes from Norman Y. Mineta San Jose International Airport, offering regional and national connectivity. The surrounding area is affluent, with a median home value of $1,044,483, and boasts a highly educated population: 44% of residents within a 10-mile radius hold a college degree. San Jose continues to be a powerhouse in the tech industry, attracting top talent and investment. The city leads the nation in GDP growth, averaging 8.3% annually over the past decade, and remains a hub for venture capital and innovation, particularly in artificial intelligence. With proximity to multiple medical centers and a thriving business ecosystem, this office space provides an ideal setting for companies seeking a prestigious address in Silicon Valley and an employee-friendly reverse commute, enabling a work-life balance.

Date on Market:

2025-10-09

Milpitas Office for Lease

McCarthy Center is Silicon Valley’s best value–a newly refreshed campus with modern design, engaging amenities and flexible solutions for companies of all sizes. From move-in ready suites with flexible lease terms to full floors and buildings, a range of options in the 1.1 million SF, 19-building campus accommodate growing companies with office, R&D and lab space. Attract and retain top talent with a full suite of amenities and modern design, including bold entries and highly-visible signage. Take your workday outdoors for fresh air and inspiration in the 10+ outdoor workspaces ideal for connection and collaboration. Host company events, networking and happy hours in the event-ready conferencing space. Energize your day with craft coffee and fresh, made-to-order dishes from The Eatery. Position your business for success and put more of what matters within reach thanks to a convenient Silicon Valley location near Hwy 237 and I-880, resort-style living at North Park, and dining, retail and entertainment at McCarthy Ranch Marketplace.

Date on Market:

2026-01-08

San Jose Flex for Lease - San Jose-Berryessa

2526 Qume Drive, Suite 17, is a modern industrial condominium in North San Jose offering approximately 5,472 square feet of functional flex space. The unit features a blend of office, warehouse, and lab/flex areas with an efficient open layout, private restrooms, natural lighting, and a ground-level roll-up door. Equipped with 400 amps of 277/480V three-phase power and situated on a ±13,674-square-foot lot, the space supports a wide range of industrial and R&D uses. With a 4/1,000 parking ratio and close proximity to major freeways, retail amenities, and San Jose International Airport, the property provides strong accessibility and operational convenience.

Date on Market:

2026-01-09

Santa Clara Industrial for Lease - Central Santa Clara

FULL RENOVATION COMPLETE of ±10,200 SF industrial R&D building, Single-tenant opportunity, or divisible to ±6,000 SF and ±4,200 SF

Date on Market:

2025-12-16

San Jose Flex for Lease - South San Jose

6872 Santa Teresa Boulevard offers ±3,447 square feet of high-identity R&D flex space available for Sublease in San Jose, California. This modern facility features an impressive glass line, abundant natural light, and a professional image along Santa Teresa Boulevard. The office area boasts 10-foot ceilings and 9-foot doors with 2-foot sidelights, creating an open and inviting workspace. The manufacturing area is equipped with HVAC, VCT flooring, skylights, and painted walls, supporting a variety of business operations. With 200 amps at 120/208 volt, 3-phase power, and a grade-level loading door, the property is well-suited for flexible R&D, light manufacturing, or tech uses. The site is conveniently located near major thoroughfares, amenities, and public transportation, making it an ideal choice for businesses seeking a strategic Silicon Valley address.

Date on Market:

2025-12-05

San Jose Office for Lease - West San Jose

Welcome to 560 S Winchester Blvd, a premier Class A office building located in the heart of West San Jose, adjacent to the vibrant Santana Row. This six-story, 100,841 SF property offers a sophisticated and modern workspace with exceptional amenities and unbeatable access. Built in 2000 and LEED Gold certified, the building blends high-end finishes with sustainable design, making it ideal for forward-thinking businesses. With flexible leasing options including a 9,410 SF direct lease and a 17,132 SF plug-and-play sublease, tenants can enjoy a move-in-ready environment complete with high-end furnishings, conference rooms, labs, and wellness spaces.

Date on Market:

2025-10-28

Fremont Flex for Lease

The property at 3754-3758 Spinnaker Ct, Fremont, CA 94538 is a flex industrial asset located in the highly desirable Bayside area of Fremont. Offering convenient access to major transportation routes including I-880, I-680, and Highway 237, the site is also just minutes from the Warm Springs BART station. The building features a mix of office and industrial space and is surrounded by a range of amenities such as the Bay Club Fitness Center, hotels, restaurants, and scenic walking and biking trails. This location is well-suited for businesses seeking a blend of functionality and lifestyle convenience.

Property Type:

Industrial

Date on Market:

2025-04-25

Milpitas Flex for Lease

720-740 S Milpitas Blvd is a multi-tenant flex building with excellent Access to Hwy 680, 880 and 237. The property sits close to numerous amenities and Milpitas BART Station. There is ample parking onsite (3.8/1000 parking available).

Date on Market:

2024-09-03

San Jose Office, Flex for Lease - South San Jose

302 Enzo Drive in San Jose offers flexible Office, R&D, and Life Science space for lease, ranging from approximately 3,872 to 23,359 square feet. This modern building features prominent signage with freeway visibility, a renovated lobby, and a variety of suite configurations to suit different business needs. Tenants benefit from robust infrastructure, including high power capacity, dock and grade loading, and a private freight elevator. The property’s location provides easy access to major amenities, parks, and trails, making it an ideal choice for companies seeking a dynamic and accessible workspace in Silicon Valley.

Date on Market:

2025-07-11

San Jose Flex for Lease - San Jose-Berryessa

R&D condos.

Date on Market:

2024-05-16

Milpitas Flex for Lease

Date on Market:

2024-06-17

San Jose Flex for Lease - North San Jose

Walking distance to light rail, retail amenties & lodging

Date on Market:

2024-05-01

Santa Clara Industrial for Lease - North Santa Clara

Multi-tenant industrial property with ample on-site parking. The site has close proximity to Hwy 101.

Date on Market:

2025-03-04

San Jose Flex for Lease - North San Jose

Date on Market:

2026-01-15

San Jose Office for Lease - North San Jose

High Profile Building & Location. Hwy. 101 Marquee Signage. Designer level appointments surround. Perimeter offices with natural light. Large collaborative workspace with conference rooms and Kitchenette. Private baths, w/shower, 4/1,000 parking, near retail amenities with easy access to major freeways, main arteries and the San Jose International Airport.

Date on Market:

2023-09-14

Santa Clara Flex for Lease - North Santa Clara

Premier office complex located in the heart of Silicon Valley. The office complex was built in 1981 and was recently renovated in 2008.

Date on Market:

2020-01-22

San Jose Flex for Lease - South San Jose

- 2- Standalone Two-Story Buildings Totaling 184,713 SF - 3,000 KVA to Each Building - Close proximity to Hwy 101, Hwy 85, Monterey Road & Retail - Trane Tracer Building Management System - Existing Data Center - 1st Fl. 16’6” Slab to Deck Height - 3.5/1,000 Parking Ratio - Dock & Grade Level Loading - Combination of Open & Dropped-Ceiling - Significant Power Savings via Bloom Box Micro-Grid Energy System - 1 block to VTA Light Rail Station - Highway 85 Signage Visibility

Date on Market:

2021-12-13

Los Gatos Flex for Lease - Los Gatos/Saratoga

PROPERTY HIGHLIGHTS • Great Central Los Gatos Location • Adjacent to Vasona Park • Easy access to Highways 17 & 85 • Close to Retail and Restaurants • Monument Signage on University Ave • 2 ISO 7 Clean Rooms • 2 Hood Vents • Multiple Lab Areas • Manufacturing & Warehouse Areas • Heavy power – 1200+ Amps • 1 Roll Up Door - 3 More Possible • 16’-18’ Clear Height • 3.3/1000 parking • Shower On-Site

Date on Market:

2021-12-13

Morgan Hill Industrial for Lease

Master planned business park Five freestanding state-of-the- art industrial buildings Suitable for advanced manufacturing, life science, industrial and warehouse uses Prominent entry features and extensive window lines Build to suit office space EV charging stations throughout the project

Date on Market:

2021-07-21

Los Gatos Office for Lease - Los Gatos/Saratoga

• Strategic West Valley Location • Professional Office Park • On-Site Deli • Great Window line • New Landscaping • 4.2/1,000 Parking • Steps Away from Los Gatos Creek Trail • Adjacent to Bay Club • Easy Access to Highways 9, 17 & 85 • Building Eyebrow & Monument Signage Available

Date on Market:

2026-01-15

Campbell Office, Office/Medical for Lease

Maximum contiguous 40,000 S. F. Great West Valley location. Near junction of 17 & 85. Not far from 280 and 101. Cross section Camden road in Silicon Valley. Walking distance to all amenities. Flexible Lease terms. Zoning and General Plan M1 (Light Industrial), Flexible Zoning that has Abundant Permitted and Conditional Uses. Office. Medical. Medical device company. Biotech. Clean room. R&D. Laboratory Lab space. Multiple clean rooms. Lots of power! Surgical center. Ambulatory surgery site. Animal surgical. Animal Hospital. Veterinary Care. Imaging center. Ortho Rehab center. Speciality center. High ceilings. Roll up doors. Shipping & Handling. Veterinary clinic. Veterinary hospital. Sports and Fitness use. Animal day care. Office General Industrial. Visible from highway 17. Signage for major tenant.

Date on Market:

2022-08-16