457 Life Science Properties for Lease in California, USA

Irvine Flex for Lease - Irvine Spectrum

9233 Research Drive | Irvine, CA Upscale Office Sublease | 100 – 6,515 SF Available Located in the heart of Irvine’s thriving business district, 9233 Research Drive offers a flexible sublease opportunity ideal for a variety of professional uses — from corporate offices to churches, non-profits, and community organizations. This upscale space is available in its entirety (6,515 RSF) or can be leased as individual executive offices.

Date on Market:

2025-07-15

Placentia Industrial for Lease - Placentia/Yorba Linda

- Free-standing R& D Type industrial building - Knott's Business Park - Lot area:32,582 SF - Total building area : 16,534SF (1st floor:14,298SF , 2nd floor2,236SF ) * Total 1st and 2nd floor office space:3,744SF * * +/- 585SF at 1st floor area with Ceiling / Lights/ HAVC . * +/- 620SF at 2nd floor :Open Loft area with Kitchen sink and Cabinets is not included in the total building area. - Ceiling height : 22 Ft - Loading: One 10' x 10 ' Ground Level Drive-in Door & One Interior Truck Well (Dock Height loading) - Power: Upgraded (Verify) - Fully Fire sprinklered - Four HAVC units on the roof - Six 4'x 8' smoke Vent & Sky Lights - 31 Parking stalls (Parking ratio:1.87/1,000SF ) - Built In 1986

Date on Market:

2025-07-06

Berkeley Office for Lease

Date on Market:

2025-06-25

Sunnyvale Flex for Lease

Date on Market:

2025-06-16

San Diego Office, Flex for Lease - Mission Valley

Date on Market:

2025-06-03

Hawthorne Office for Lease - Hawthorne/Gardena

Located at a prominent intersection of Hawthorne Blvd. & W. 136th St. in populated area. On and off-ramp access from the 105 Freeway & a few minutes away from Hawthorne Airport & 405 Freeway National & regional retailers in the vicinity: Denny’s, El Pollo Inka, Carl’s Jr., Dunkin’ Donuts, Bossa Nova, Autozone, O’Reilly Auto Parts, NAPA Auto Parts, Planet Fitness, 7-Eleven, True Value Hardware, CosmoProf & more. Available for OFFICES, medical, defense contractors, educational, events, assembly, school, research lab, religious complex, film or sound editing studio (subject to City approval), etc.

Date on Market:

2025-05-05

Mission Hills Office/Medical for Lease - Eastern SFV

This outpatient medical building is situated adjacent to the Providence Holy Cross Medical Center in Mission Hills, CA. This 3-story outpatient medical office building, strategically located with immediate access to the San Diego (405) and Simi Valley (118) Freeways, offers a range of medical office space for lease. Notable features include the presence of an MRI center, an outpatient diagnostic center, and a full-service pharmacy, making it an ideal choice for healthcare professionals looking for office space with cutting-edge amenities. Join this thriving medical community in the San Fernando Valley, just 20 miles northwest of Los Angeles.

Property Type:

Office

Date on Market:

2025-04-30

Hayward Flex, Industrial for Lease - Hayward/Castro Valley

Bay Center Business Park’s commercial real estate includes three complexes, each with multiple buildings and a freestanding distribution center in a prime Hayward, California, location. In addition to industrial space, it offers biotech spaces just across the bridge from the Peninsula. This light industrial, warehouse, and lab portfolio offers suites ranging from 2,400 to 18,000 square feet. With this large amount of square footage, future tenants have expansion opportunities within a high-profile and professional setting. The availabilities have 18 feet of clear height, dock and grade-level loading options, levelers, 100 to 800 amps, and 480/277 volts of power. Most industrial units also include office space that comprises private offices, reception areas, and conference rooms. Centrally located in Hayward, a large metro area set on the coast and hills of Northern California. Benefiting from superior highway connectivity to Highway 92 and Interstate 880, providing quick connections to business hubs in Oakland, Redwood City, Palo Alto, San Jose, and San Francisco. Users have two options for transporting cargo overseas via plane at the Oakland International Airport, 13 miles away, and the San Francisco International Airport, 20 miles away. The Port of Redwood City is a 27-minute drive away for freight needs. Hayward, California, is a vibrant city in San Francisco's Bay Area. Hayward lies along the northern coast of California, 65 miles west of Sacramento and 380 miles northwest of Los Angeles. A wide variety of technology and finance industries call this area home. With a population of 162,954 as of 2020, Hayward is the sixth-largest city in the Bay Area and the third-largest in Alameda County.

Date on Market:

2026-01-28

Emeryville Flex for Lease

Atrium Labs is an exciting new lab conversion in the heart of Emeryville’s growing Life Science hub. Thoughtfully designed specifically for scientific advancement, Atrium’s state-of-the-art lab space is balanced by its striking aesthetics and curated selection of amenities.

Date on Market:

2023-12-14

Parlier Office, Industrial for Lease - E Outlying Fresno County

Building is a mix of high quality office, lab, production and warehouse space. Very secure. Includes elevator, locker rooms, cold boxes, and covered parking. Almost entire building is climate controlled.

Date on Market:

2025-03-22

Santa Clara Office for Lease - Central Santa Clara

3100 Central Expressway is a ±39,176 SF, two-story state-of-the-art life science facility designed to support cutting-edge research and development. The building features a variety of specialized lab spaces, including fume hoods, workbenches, and dedicated hazardous storage with two H2 Hazardous Storage and Containment facilities. Additionally, the property offers robust backup power systems, executive office suites, and a spacious, modern lobby to enhance functionality and comfort.

Property Type:

Flex

Date on Market:

2025-03-19

San Diego Office, Flex for Lease - Sorrento Mesa

Date on Market:

2025-02-28

Napa Office for Lease - Napa County

50,000 SF, two-story, Class ‘A’ office building with expansive lobby area. Abundant parking; 4/1,000 SF. Immediate access to Highways 29 & 12, and to Napa Airport

Date on Market:

2026-02-12

Fairfield Office, Office/Medical for Lease - Fairfield/Suisun City

Green Valley Executive Center, located at 5030 Business Center Drive, is a high-impact Class A office property offering approximately 50,000 square feet of professionally maintained, highly adaptable space. This freestanding building makes a bold impression with its prominent street presence, clean architectural lines, and strategic location in the heart of Fairfield’s premier business corridor. It’s the ideal solution for companies seeking a sophisticated headquarters, regional office, or operational hub that combines flexibility, visibility, and long-term value. Set on a spacious, well-landscaped lot with ample onsite covered parking under solar structures, Green Valley Executive Center features a modern layout designed to support both internal productivity and external professionalism. The interior buildout includes multiple private offices, executive boardrooms, collaborative open workspaces, and welcoming reception areas—all finished to a high standard. Whether hosting clients or growing a high-performance team, the space strikes the right balance between comfort and capability. In addition to its premium office environment, the building offers open-span areas ideal for training rooms, operations support, or technical functions. The layout is easily customizable, giving tenants the ability to adapt over time without outgrowing the space. Located just minutes from Interstate 80, Green Valley Executive Center offers quick access to Napa, Sacramento, Walnut Creek and the greater Bay Area. It sits among a strong mix of professional services, technology, and production-based businesses—creating a dynamic, synergistic environment for growth-minded companies. For those seeking a business location that pairs Class A quality with operational flexibility, Green Valley Executive Center at 5030 Business Center Drive delivers on every front. This is more than just a place to work—it’s a foundation for long-term success.

Date on Market:

2026-01-27

San Jose Office for Lease - South San Jose

6140 Hellyer Avenue is a freestanding, single-story commercial property with 4,478 square feet of interior space. Built in 2006, it features 100% office buildout and a modern exterior with strong curb appeal. The building is situated in Hellyer Commons Industrial Park and is zoned Industrial Park (IP), offering a wide range of permitted and conditionally permitted business uses. The design emphasizes professional functionality with a balance of privacy and openness. Inside, you'll find multiple private offices, a large shared kitchen, open team workspaces, and common areas ideal for meetings or collaborative sessions. Optional furniture and tenant improvement packages allow new occupants to customize their environment with minimal hassle. This property stands out for its strategic location and ease of access. It's located just minutes from Highways 101 and 85, providing efficient connectivity throughout the Bay Area. The surrounding area is quiet, green, and offers a peaceful work atmosphere while maintaining proximity to South San Jose’s business districts, restaurants, and retail services. Key building features include: Fully built-out interior with drop ceilings, central HVAC, and private kitchen ADA-compliant design and restroom access Sprinkler system and emergency lighting Secure, single-entry layout for improved access control 36 dedicated surface parking spaces High-speed internet included Bike-friendly amenities and adjacent walking trails Energy-efficient construction with ample window coverage The IP zoning permits a wide range of businesses, including office users, clean-tech and R&D firms, biotech and pharmaceutical companies, and certain medical or therapeutic practices. Businesses seeking to operate as a medical office may apply for a Special Use Permit with the City of San Jose. Approval typically depends on the type of practice (e.g., non-surgical vs. surgical, patient traffic levels, equipment used). The building's layout and infrastructure support this kind of conversion. Whether you're seeking executive offices, research space, or clinical functionality, 6140 Hellyer offers a balanced environment with flexibility, location advantages, and move-in readiness. Reach out today to schedule a tour or request zoning compatibility guidance. Text, call, or email today: Piyush Kothary (408) 656-7643 Kothary@yahoo.com

Date on Market:

2025-07-21

San Diego Flex for Lease - Sorrento Mesa

This property features a refreshed lobby, updated lighting, and modern office finishes. It includes robust infrastructure to support a 175KW emergency generator, a new roof, and a 3,500 lb service elevator. The facility offers a shipping and receiving area with a roll-up door, remodeled restrooms and showers, and upgraded 3,000-amp electrical service to meet a variety of operational needs.

Date on Market:

2024-12-19

San Diego Office for Lease - Rancho Bernardo

Property Type:

Flex

Date on Market:

2024-12-17

San Leandro Flex for Lease

Date on Market:

2024-12-13

Carlsbad Flex for Lease

Date on Market:

2024-12-09

Santa Clara Office, Flex for Lease - North Santa Clara

- Full-building available - Full Kitchen Ground Floor - First Floor 11’ Ceiling Height (Not Clear Height) - Second Floor 10’ to Ceiling Tile 3.000 Amps - Ground Floor Outdoor Patio - Elevator Cold Room in Warehouse - 4 Standard and 1 Accessible Bathroom - LED: 2/29/26 - 7 Cutouts for Roll Up Doors - 5 Showers on First Floor

Date on Market:

2024-11-21

Fairfield Flex for Lease - Fairfield/Suisun City

Manufacturing/Industrial Building. Former food production facility for Abbott Nutrution. Solano Business Park, and Fairfield as a whole, offers high-quality water and extensive sewer capacity, making it an ideal location for numerous food and beverage production facilities

Property Type:

Industrial

Date on Market:

2024-11-20

Los Angeles Flex, Industrial for Lease - Inglewood/South LA

St. Andrews Place is fully built-out for Retail, Distribution, Manufacturing and Cultivation with ±15,201 sf of approved production space and ±7,500+ sf of expansion space that totals ±22,701 SF of building on ±33,794 of land. The current configuration allows for flexibilty for any user either looking to expand their cultivation footprint or manufacturing and distribution. Originally built in 1946 the majority of the existing Improvements were completed in 2021. The Property features HVAC throughout the majority of the building, 20 ft clear height, two ground-level doors, brick and concrete block construction, and generous parking for the area. While all compliant uses will be considered, the Property currently offers licensing for Cultivation (and/or Nursery) and Manufacturing allowing an operator speed to market with an existing foundation of partial improvements and regulatory compliance.

Date on Market:

2025-03-24

Redwood City Flex for Lease - Foster City/Redwood Shrs

Property Type:

Office

Date on Market:

2024-10-02

San Diego Flex for Lease - Sorrento Valley

Discover unparalleled access and convenience at GENESIS-Roselle, a premier ±40,000 SF, two-building life science campus in the heart of Sorrento Valley. Strategically positioned with seamless freeway access, GENESIS-Roselle is being transformed into a hub for San Diego’s biotech community. Set for completion in April 2025, this newly renovated campus will offer state-of-the-art lab spec suites designed to meet the evolving needs of life science companies. With flexible layouts and advanced infrastructure, GENESIS-Roselle is poised to drive innovation and growth in the region. Explore the opportunities and elevate your business at GENESIS-Roselle.

Date on Market:

2024-08-01