447 Life Science Properties for Lease in California, USA

San Diego Office, Flex for Lease - Mira Mesa/Miramar

Compressed air. Pre-installed caballing. Power – 1200 amp 277/480 volt.

Date on Market:

2024-11-26

Santa Ana Office/Medical, Medical for Lease

Date on Market:

2026-03-03

San Mateo Office, Flex for Lease

GENESIS 1400 Fashion Island offers 200,000-square-feet of Class A life science research space in the heart of San Francisco’s Peninsula. Delivering the GENESIS spec program, the project provides small- to mid-size lab and office suites ranging from 10,000- to 25,000-square-feet. Floorplates vary in size offering a variety of single and multi-tenant options. The building underwent an extensive upgrade including all new MEP (mechanical, electrical, plumping) infrastructure, a new service elevator, and a backup generator to bring it to today’s lab industry standards. GENESIS fronts Highway 92 with immediate access to Highway 101, Interstate 280, and the San Mateo Bridge. The San Francisco International Airport is seven miles north of the project and the Mariners Island Caltrain Shuttle stop is across the street. The property features extensive landscaping with beautiful surrounding redwood trees, a central outdoor plaza with seating areas, and ample parking both at surface level and with a 3-level parking structure. EV charging stations will be provided for use. Located in the center of the peninsula, between Stanford and UCSF, this location offers unparalleled access to the world’s leading innovation clusters which enables growing companies to attract and retain talent from across the Bay Area’s research institutions. Come be a part of GENESIS - The Root of Innovation.

Date on Market:

2023-09-14

Hayward Flex for Lease - Hayward/Castro Valley

Date on Market:

2026-01-23

Alameda Office for Lease

The Office Park at Marina Village is a 1.4-million-square-foot waterfront campus and the most active Life Sciences cluster in the Bay Area. The Retreat is the new tenant amenity building with a fitness facility and a conference center. There is a dedicated private shuttle to 12th Street, enabling commuters to access BART. Recently, a new campus ferry terminal was added to provide additional convenience. The Research Park at Marina Village is ideally located, 5 minutes from Downtown Oakland, 20 minutes from Downtown San Francisco, and 22 minutes from Downtown Walnut Creek.

Date on Market:

2024-01-24

Corona Industrial for Lease - Corona/Eastvale

Ideally situated in Corona on the border of Riverside County and Orange County, Green River Ranch Business Park acts as a gateway to all of Southern California. With direct visual exposure to SR-91, Green River Ranch Business Park offers rare build-to-suit opportunities with a highly desirable location.

Date on Market:

2022-03-14

San Diego Retail for Lease - Downtown

A WATERFRONT DISTRICT WITH RETAIL AND LAB SPACE RaDD is a convergence of best-in-class culinary talent, retail, and life science labs situated in a one-of-a-kind architectural setting. Across 1.7 million SF of commercial space, we are carefully curating a 150,000 SF retail district unique to San Diego’s iconic waterfront. Surrounded by a hub of movement – planes, trains, pedestrians, cruise ships, the ferry to Coronado, runners on the Embarcadero path – all major paths hug the project’s perimeter. The site is like no other. We are creating an undeniable draw that will pull both locals and visitors down to the water’s edge.

Date on Market:

2024-09-27

Newbury Park Flex for Lease - Thousand Oaks/SE County

Class A office/flex building located in the Conejo Spectrum submarket. Great opportunity for an office/R&D or a life science/biotech user. Creative, open area buildout. Owner plans to demo some of the existing improvements after the current tenant vacates.

Date on Market:

2022-02-25

Berkeley Office, Flex for Lease

Located on the vibrant Emeryville Greenway, Foundry31 is in the heart of the East Bay innovation cluster. Once an industrial building, this converted Life Sciences building now offers state-of-the-art biotech lab space ready for your creativity. High quality amenities and transportation options make the site a top choice for talent.

Date on Market:

2025-08-25

Emeryville Office for Lease

SteelWave leading the way in life science delivering some of the most exciting creative life science space in the market. theLAB Emeryville reborn with brand-new cutting-edge infrastructure and, blank-slate lab spaces, your team has ample room to push boundaries and discover breakthroughs. Emerged as one of the fastest growing life science clusters in the US, it’s no surprise you are surrounded by some of the largest employers in the industry along with leading area research universities, and national laboratories. theLAB Emeryville is centrally located in Emeryville, California, the new frontier when it comes to life science and biotechnology. From past to future - the Sherwin-Williams Company constructed this historic paint factory in 1919 with operations running in to the mid 2000’s. theLAB Emeryville underwent a long-awaited renovation and repositioning conversion to an adaptive re-use Class A life science space. Inside, high-end modern lab space, common areas including new lobbies, restrooms, and elevators. At theLAB Emeryville, simple yet elegant finish tie into the buildings historic character merged with stunning contemporary interior offices. Three bays with full height glass panels lets in an abundance of natural light. Unparalleled location with bountiful entertainment, dining, and shopping experiences providing the desirable work life balance. theLAB Emeryville will feature a “pass through” between Horton Street and the neighboring Lennar development on the west side of the property to provide pedestrian and bicycle access between Horton Street and the Lennar Project.

Property Type:

Flex

Date on Market:

2022-02-09

Emeryville Flex for Lease

Property Type:

Industrial

Date on Market:

2021-12-07

Brisbane Flex for Lease - Brisbane/Daly City

The Shore at Sierra Point consists of 5 buildings with all the modern-day features businesses demand. Located in Brisbane, California. This LEED pre-certified campus offers bay-front walkways, ample green space, retail and dining within walking distance.

Date on Market:

2023-03-20

Alameda Office/Retail, Flex for Lease

Alameda’s newest collection of Class A STEM, Life Science/R&D availabilities, located within the Harbor Bay’s growing life science cluster anchored by Abbott, Exelixis and Penumbra. Walkable amenities, Cafe Jolie Petit, on-site building engineer, 4-sided window lines with Bay views, free parking @ 3 per 1,000, BART Shuttle service, San Francisco Ferry service 25 minutes to/from San Francisco Ferry Building. Alameda Municipal Power - more reliable than PG&E at 25% less cost. Outdoor fitness Pad.

Date on Market:

2025-11-12

San Jose Flex for Lease - South San Jose

Welcome to the bioCube, Silicon Valley's premier biotech incubator within the Optical Tech Park at 5941 Optical Court in South San Jose. Introducing state-of-the-art labs and collaborative workspaces perfect for startups, spin-offs, and large companies that value Silicon Valley's unique talent and prestige. bioCube is a place where science and discovery flourish through move-in-ready wet lab spaces with a vibrant community of pioneers today. bioCube has lab suites ranging from 1,452 to 2,479 square feet and include central DI water and vacuum, fume hoods, emergency shower stations, HazMat storage cabinets, and 800 KW emergency power. 5941 Optical Court is bioCube's original headquarters. This recently renovated Class A facility spans 70,000 square feet and includes modern labs, offices, conference rooms, and shared equipment. Plus, chic community spaces to enjoy, such as reception, a café-style kitchen, a break room, and a sundrenched courtyard with a fire pit and comfy chairs. For an enhanced tenant experience, this innovation hub provides on-site support and best practices to maximize research capabilities. The Optical Tech Park's strategic location provides easy access to key transportation hubs, including Caltrain, VTA Transit, and the San Jose International Airport. Additionally, tenants benefit from a wealth of nearby amenities and an ideal position just a mile north of the intersection of the 101 and Highway 85. Many corporate businesses such as Olympus, Stryker, and Renesas surround the property, providing a wealth of expertise to the area. Experience the fully functional, turnkey labs with modern equipment and common space, join a community of innovative scientists at bioCube in South San Jose, and connect with Transwestern to schedule a tour.

Date on Market:

2024-01-12

San Francisco Flex for Lease - Mission/Potrero

Date on Market:

2022-02-17

San Carlos Office, Industrial for Lease - Belmont/San Carlos

ground floor former retails space that could be office space. 6.800 RSF of warehouse with 20'-22' clear height and two over-sized grade level roll up doors.

Date on Market:

2026-02-02

San Diego Flex for Lease - Del Mar Hts/Carmel Valley

Pacific Plaza @ Torrey Hills offers excellent visibility and signage; showers, lockers and fitness facility on-site; state-of-the-art energy management system; computerized security, HVAC and lighting; integrated network for fiber optic cable telephone system, and over 50% of the parking is covered. Situated on a bluff offering panoramic views of the Pacific Ocean, Torrey Pines and Del Mar, Pacific Plaza @ Torrey Hills has unequaled freeway visibility with exposure to over 275,000 cars a day. It is located in the center of San Diego's fastest growing and most dynamic area, with proximity to hotels, restaurants and retail services with executive, moderately priced single and multi-family housing nearby.

Date on Market:

2026-03-05

San Diego Flex for Lease - Sorrento Mesa

New 325,000 SF Life Science / Lab / Biotech building by Longfellow. Scalable 70k+ SF floor plates Spec Suites delivering Q2 on floor 2 - 14,403 SF and 23,934 SF (can be combined) Private tenant terraces on each floor - 4 per floor Amazing views Top Floor (L5) Amenity Hub includes: - Tenant hospitality lounge, bar and private conference rooms - 200 person conference facility and pre-conference lounge and bar area - Indoor/outdoor fitness center - Spa quality showers and lockers with Sauna/Steam and Cold Plunge - Landscaped open air rooftop patio Dock Loading with managed shipping/receiving and freight elevator LEED Gold Certification fitwel certified All-Electric building Curated Amenity Programming by Longfellows' ELEVATE team

Date on Market:

2025-04-02

San Francisco Medical for Lease - West of Van Ness

Five-story Class A medical office building located in Pacific Heights on the Pacific Campus of California Pacific Medical Center at Webster and Clay Streets. The property is home to more than 150 physicians representing a broad range of specialties, including internal medicine, orthopedics, and OB/GYN. Features include an energy-efficient design with a bipolar ionization air-filtration system, newly upgraded elevators, a clean and well-maintained environment, a well-lit and freshly painted parking garage, a spacious lobby showcasing the work of local artists, and on-site concierge and security.

Property Type:

Office

Date on Market:

2026-01-06

Berkeley Retail for Lease

• New construction, high-visibility retail space • Spaces 1500 and 1510 can be combined for total of ±3,436 RSF • Call Broker for Lease Rate • 27 parking spaces dedicated to retail • High-traffic shopping corridor • Almost entire block of retail co-tenancy – professionally managed • Southern spaces are setup for venting and a pre-installed grease interceptor capable of a smaller or larger restaurant use • Dense food and home improvement corridor • Quick walk to Whole Foods Market, REI, Philz Coffee, Chipotle, Walgreen’s, Road Runner Sports, North Berkeley BART, Acme Bread, and many other local eateries and businesses • 9 blocks to Fourth Street Shopping District • 2.5 miles to Emeryville Public Market • 2 miles to Downtown and UC Berkeley • 3 miles to Powell Street Plaza and Shops • Easy freeway accessibility and SF Bay Bridge access • Near hundreds of new housing units approved or under construction. Currently ±1,400 units (across 20 projects) have been submitted and are pending review • Nearby companies include Clif Bar, Pixar, LeapFrog, Meyer Sound, Title Nine Sportswear, City Sports Gym, Acme Bread, Climax Foods, Whole Foods Market (Regional), Metropolis Baking, TCHO Chocolate, F’real Foods, Bolt Threads, GU Energy Labs, Ripple Foods, La Tourangelle Oils, Perfect Day Foods, Wild Earth Dog Food, Peet’s Coffee Corp HQ, Twelve, and Prime Roots • Bioscience companies in the vicinity include Bayer, Xoma, Aduro Biotech, Newomics, Dynavax Technologies, Caribou Biosciences, and Lygos

Property Type:

Multifamily

Date on Market:

2024-05-30

San Diego Office, Flex for Lease - Downtown

Date on Market:

2026-02-24

Los Angeles Office/Medical for Lease - Culver City

The Luzzatto Company began construction on "The Depot" in May 2021 with a completion date of 4Q 2022. The Depot is a ground up, Class A, transit-adjacent, architecturally significant, environmentally-conscious, creative office project with over 17k feet of landscaped outdoor patios and decks, two levels of secured subterranean parking, and 15' clear ceilings. The Depot is built with steel, concrete, wood and glass. Located only 2 blocks from the intersecting MTA stops of the blue line running along Exposition from downtown to the beach, and the new LAX line running along Crenshaw, from LAX/Inglewood to this location, The Depot may be the most transit-friendly development in the entire city. With 360 degree views of Los Angeles through towering palm trees, the historic West Adams location is unique, vibrant, and classic Los Angeles.

Property Type:

Office

Date on Market:

2020-12-02

Santa Ana Office/Medical, Medical for Lease - Main Place Area

Medical & Professional Campus, with easy FWYS 5, 22, 55, 57 access, Surface Parking with Ratio of 6 per 1,000. On site Medical Lab, State of the Art Medical Imaging &Radiology and Pharmacy, State of art Tenant Improvement available for qualified tenant. Visible from the 5 Freeway and Immediate Access to 3 Major Southern California Freeways, 5, 22, 55 and close proximity to 57, Located next to the Hard Corner of 17th Street and Grand Avenue with the car count of approximately 80,000 cars per day.

Date on Market:

2025-04-16

South San Francisco Flex for Lease

Kilroy Oyster Point Phase 2 is now delivering: three state-of-the-art buildings totaling approximately 865,000 square feet in the heart of South San Francisco—the birthplace of biotechnology. Kilroy Oyster Point Phase 2 is a premier waterfront life sciences environment designed to accelerate scientific innovation within one of the Bay Area’s most established biotech clusters. Set along Oyster Point’s shoreline, the campus blends purpose-built lab and office buildings with expansive outdoor zones, providing an energized setting that supports collaboration, wellness, and productivity. Tenants benefit from next-generation infrastructure including significant floor load capacities, large open floor plates, and LEED Gold–targeted design, all arranged within an interconnected outdoor village featuring amphitheater seating, a conference center, fitness amenities, and Farewinds restaurant and café. The location offers both inspiration and convenience, just steps from beaches, trails, hotels, and immediate access to ferry service and major freeways, making Phase 2 a destination for companies seeking an elevated, amenity-driven research workplace.

Date on Market:

2025-12-04