461 Life Science Properties for Lease in California, USA

Fremont Flex for Lease

Property Type:

Industrial

Date on Market:

2026-01-29

San Diego Flex for Lease - Sorrento Valley

Date on Market:

2026-01-28

San Carlos Flex for Lease - Belmont/San Carlos

Alexandria is known for its high-quality and diverse client tenant base, which includes renowned academic and medical institutions, multinational pharmaceutical companies, public and private biotechnology entities, United States government research agencies, medical device companies, industrial biotech companies, venture capital firms, and life science product and service companies.

Date on Market:

2026-01-26

Petaluma Industrial for Lease - Petaluma/Cotati/Rohnert

Approximately 2,328 SF of versatile warehouse/creative space with 14-foot ceiling height and two grade-level roll-up doors providing convenient access for loading and adaptable uses. The flexible footprint and high ceilings make this suite ideal for a variety of concepts, including fitness or health facilities, studios for art, dance or martial arts, creative workspaces or artisan shops, retail, catering services, printing and publishing, and research and development—among others. Dual roll-up doors enhance functionality for businesses needing easy drive-in access, and the open layout allows users to customize the environment to their specific operational needs. Situated at 660 Lakeville St in Petaluma, this well-located commercial property enjoys excellent connectivity and exposure. The site is positioned just off U.S. Highway 101, providing easy access to the broader Sonoma County region and convenient commuting to Santa Rosa, Rohnert Park, and Marin County. The surrounding area supports a mix of industrial, service, and creative businesses, with nearby options for dining, retail services, and amenities that complement commercial activity. Petaluma’s vibrant downtown and historic core—with shops, restaurants, and cultural destinations—are a short drive away, enhancing the appeal for employees and customers alike. The location also benefits from strong walkability and proximity to regional transit options.

Date on Market:

2026-01-22

Altadena Office for Lease - Pasadena

Located on bustling Lake Avenue in Altadena, this freestanding medical office building offers versatility for a range of professional uses. Built in 1951 and situated on a 7,781 sq. ft. lot, the 2,092 sq. ft. structure combines functional design with convenient amenities. The existing layout includes a welcoming lobby/waiting area, reception/business office, multiple exam rooms, lab room, private offices, and a breakroom with kitchenette. On-site surface parking for eight vehicles is available at the rear of the property. The building’s proximity to public transportation and freeway access enhances connectivity for staff and clients. Surrounded by active redevelopment and recent construction, the location benefits from a renewing commercial corridor. The property is suited for medical practices, dental offices, or general office use, providing flexibility for owners and tenants alike in a desirable Southern California setting.

Date on Market:

2026-01-22

Newbury Park Industrial for Lease - Thousand Oaks/SE County

Date on Market:

2026-01-21

Sunnyvale Office/Medical for Lease

Date on Market:

2026-01-20

Sunnyvale Industrial for Lease

Nestled in the dynamic and innovation-driven city of Sunnyvale, 388 Oakmead Parkway offers an exceptional opportunity for businesses looking to thrive in one of the most sought-after locations in the Bay Area. With convenient access to major tech campuses, highways, and public transit, this property combines modern functionality with strategic positioning. Dedicated Lab with 10 Racks • Can operate 10 H200 GPUs, Management Nodes & Petabyte Storage Clusters • 1 megawatt of power to building • Enough power available to expand to a full B200/B300 GPU Cluster • Each rack includes two 208V 3 phase 48A PDUs

Date on Market:

2026-01-15

Monrovia Industrial for Lease - Western SGV

This flex industrial property located at 1017 S. Mountain Ave in Monrovia offers 17,700 SF of adaptable space combining warehouse and office functionality. The property is positioned on a 33,976 SF lot that includes a secure private yard, providing flexibility for staging and operational requirements. A bonus mezzanine expands potential workspace options and adds versatility for various industrial or creative uses. Connectivity is a key advantage, with immediate access to the I-210 and I-605 freeways, facilitating efficient logistics across the San Gabriel Valley and broader Los Angeles region. Heavy power availability supports manufacturing or production-based operations, and two 12’ truck doors ensure smooth loading and unloading capabilities. The property also includes 35 on-site parking spaces, accommodating both employees and visitors. Nearby occupiers include well-known auto dealerships such as BMW of Monrovia and Sierra Chevrolet, reinforcing the property’s appeal among automotive and complementing industries. Zoned for manufacturing (M), the property aligns with diverse industrial uses. Planned major interior renovations will further enhance the space, creating modernized interiors suitable for today’s business standards. Can be combined with neighboring buildings to a total of 46,591 SF.

Date on Market:

2026-01-09

Carlsbad Flex for Lease

Date on Market:

2026-01-05

San Diego Flex for Lease - Sorrento Mesa

Property Type:

Office

Date on Market:

2025-12-15

San Jose Flex for Lease - South San Jose

6872 Santa Teresa Boulevard offers ±3,447 square feet of high-identity R&D flex space available for Sublease in San Jose, California. This modern facility features an impressive glass line, abundant natural light, and a professional image along Santa Teresa Boulevard. The office area boasts 10-foot ceilings and 9-foot doors with 2-foot sidelights, creating an open and inviting workspace. The manufacturing area is equipped with HVAC, VCT flooring, skylights, and painted walls, supporting a variety of business operations. With 200 amps at 120/208 volt, 3-phase power, and a grade-level loading door, the property is well-suited for flexible R&D, light manufacturing, or tech uses. The site is conveniently located near major thoroughfares, amenities, and public transportation, making it an ideal choice for businesses seeking a strategic Silicon Valley address.

Date on Market:

2025-12-05

Torrance Industrial for Lease

Located in the heart of Torrance, this versatile industrial building offers excellent functionality with immediate access to major commercial amenities. The property is just minutes from Torrance Airport and surrounded by a strong mix of nearby retail, restaurants, and shopping centers, making it ideal for a wide range of industrial or service-oriented users. Its prime location and convenient accessibility provide strong appeal for both operations and customers.

Date on Market:

2025-12-04

San Diego Office/Medical for Lease - Sorrento Mesa

Rare owner-user or investment opportunity — a free-standing building in Sorrento Mesa offering the flexibility to occupy all or a portion of the building Abundance of on-site parking and adjacent street parking Exceptional visibility and signage, expansive window line, and elevator-served Zoning allows for a mix of uses Ease of commute with central location, short distance to freeway, and nearby transit options Synergy with adjacent tenants - situated in San Diego’s technology, life science and pharmaceutical hub

Property Type:

Office

Date on Market:

2025-12-03

San Carlos Flex for Lease - Belmont/San Carlos

Biotech, lab, pharma, and GMP manufacturing facility designed for advanced life science operations. Situated on a 28,529-square-foot land parcel (APN: 046-161-070), the building features two process/clean rooms — Class 10,000 and 100,000 (or Grade C and D) — equipped with two large floor scales. The facility includes a microbiology lab and a chemistry lab, both supplied with purified water, along with two fume hoods, a large autoclave, and a COP bath. Office accommodations consist of two private offices, a general office area, a server room, and two ADA-compliant restrooms. The property is supported by 1,600 amps of 277/480V power and an 85 kW, 208V/3-phase emergency standby generator. Additional features include a warehouse with HVAC and Title 24 lighting, a large utility room housing four boilers, a pure steam generator system, and oxygen and nitrogen lines. The site provides 17 on-site parking spaces and offers convenient access to Highway 101 via Holly or Whipple Avenue, just minutes from the Alexandria Center for Life Science San Carlos campus. Facility amenities also include a cold room (2–8°C), cooling towers, water chillers, RODI generators, and a waste equalizer/neutralizer system, making it an exceptional opportunity for biotech, pharmaceutical, or GMP manufacturing users.

Date on Market:

2025-11-13

San Diego Office for Lease - Sorrento Mesa

Date on Market:

2025-09-11

San Carlos Retail for Lease - Belmont/San Carlos

Here’s a summary of what we’re offering, subject to credit and financial review. Two (2) spaces are available for lease, 1 vacant 3,172 sf retail space that can be converted to restaurant with help from the landlord, OR, 1 turn-key 2,050 sf restaurant space. 633 Laurel Street, San Carlos, CA Lease Opportunity 3,172 sf of Rentable Retail, Restaurant, Fitness, Classes, or Office space $3.75/sf NNN + $1.32/sf estimated CAMs = $5.07/sf Gross Rent x 3,172 sf = $16,082.04 Gross Rent per month with 3% annual increases to the base rent and pass through CAMs. 10 Year Lease with 2 x 5 year options. Free Rent During Permitting and Construction Up to 5 months of free rent for tenant to get building permits and to complete construction. Construction Expense Reimbursement from the Landlord (TI Credit) For Restaurants: $63/sf TI credit x 3,172 sf = $200,000 in additional free rent credit after the above 5 months of free rent to get permits and do construction (with strong creditworthiness). 637 Lease Summary 2,050 sf = $3.75/sf NNN + $1.32/sf CAMs = $10,393.50 Gross per month in a NNN lease structure. Lessee shall pay for all water, gas, heat, light, power, telephone, trash and other utilities. 3% annual increases to the base rent and pass through CAMs. 10 Year Lease with 2 x 5 year options. $100,000 key money required. 200 Amps of power, water and gas in place. Upgrade to 400 amps in process. 633 Laurel: Warm Shell Condition 200 Amps of power in place stubbed to suite. Upgrade to 400 amps in process. Water and Gas stubbed to suite. HVAC in place. 2 bathrooms in place We’ve got a fully drafted lease ready to sign upon review of your concept and financials. Average household Income within San Carlos = $335,000 (Within 1 Mile) Daytime Employment Total = 16,490 employees Annual Expenditures: Food and Alcohol = $85,169,403 Annual Total Visits To 600 Block = 1,900,000 Tour with exclusive broker, Alex Kent. Call 650-793-0541. Further, the city has approved 3,000,000 square feet of Class A Office and Biotech development, mostly by the REIT Alexandria. This means approximately 3,000,000 sf / 250 sf = 12,000 new employees in San Carlos alone. Plus, Redwood City next door approved another 5,000,000 sf, and so on and so on. We’ve also approved about 2,800 new housing units. With 2.5 people per unit, that’s 7,000 additional residents. https://www.sancarlosdowntownplan.com/ ZONING MU-DC-100: Mixed-Use Downtown Core: Allowable uses: retail, restaurant, commercial, and office (front 2,500 sf) uses, as well as res. dev. of up to 100 units/acre. Family Child Care, Small & Large, Residential Care Facilities, Instructional Services/Classes*, Artist Studios*, Vehicle Sales/Leasing*, Banks*, Theaters*, Bars*, Restaurants*, Convenience Grocery Store*, Food Preparation, Bed & Breakfast, Hotels* (if redeveloped with upper floors), Garden Center*, Business and Professional*, Medical and Dental* (if redeveloped with upper floor), General Personal Services*. *See potential limitations or permit process, if any in City of San Carlos municipal code and from a conversation with a city planner. https://www.codepublishing.com/CA/SanCarlos/#!/SanCarlos18/SanCarlos1805.html#18.05

Date on Market:

2025-04-08

San Jose Office for Lease - West San Jose

Welcome to 560 S Winchester Blvd, a premier Class A office building located in the heart of West San Jose, adjacent to the vibrant Santana Row. This six-story, 100,841 SF property offers a sophisticated and modern workspace with exceptional amenities and unbeatable access. Built in 2000 and LEED Gold certified, the building blends high-end finishes with sustainable design, making it ideal for forward-thinking businesses. With flexible leasing options including a 9,410 SF direct lease and a 17,132 SF plug-and-play sublease, tenants can enjoy a move-in-ready environment complete with high-end furnishings, conference rooms, labs, and wellness spaces.

Date on Market:

2025-10-28

Sunnyvale Office/Medical for Lease

o Easy access to HWY 101, 85, 82, 280, 880 & 237. o Ample Parking On site o Located near numerous Fortune 500 high tech companies o Suite 1: 2,694± SF o $2.50 PSF Modified Gross o Front desk receptionist area o Two bathrooms o 5 private offices o Common area for office cubicles o Conference room with white board o Storage closet o Break room/kitchen with table

Property Type:

Flex

Date on Market:

2026-05-14

Woodland Office for Lease - Davis/Woodland

Prime downtown location situation in the heart of Woodland's Historic Downtown Corridor. This property offers excellent visibility, workability and convenient access to the new Courthouse, City Hall and County Admin building. Ample parking (fenced with automatic gate).

Property Type:

Flex

Date on Market:

2026-05-14

Carlsbad Flex for Lease

Surrounded by leading biotech and manufacturing firms such as Thermo Fisher Scientific, Beckman Coulter, and TaylorMade, the property benefits from proximity to McClellan-Palomar Airport, Carlsbad Premium Outlets, and a wide array of hospitality and retail amenities including Costco, LEGOLAND, and La Costa Resort. The sublease runs through November 30, 2028, offering stability and flexibility for growing operations. Existing lab and office furnishings may be available upon request, streamlining move-in for qualified tenants.

Date on Market:

2025-10-02

San Carlos Flex for Lease - Belmont/San Carlos

Extensive glass throughout, Full HVAC throughout, Sprinklers

Date on Market:

2025-10-02

Watsonville Office for Lease

60 Penny Lane is a 4422sqft+/- two story single tenant medical-office building in the heart of Watsonville's commercial business-medical district. The building enjoys lush landscape, HVAC, ample parking, high visibility and traffic, and walkability to dining, shops, gym, bus line and more! The interior is in excellent condition and includes an entry waiting area, reception area, multiple private office/exam treatment rooms, a large open floor plan, two private bathrooms with both laundry and shower access, staff areas, water access throughout, tons of natural light, and an upstairs area with open work space and two additional private office/exam treatment rooms.

Date on Market:

2025-09-24

San Diego Flex for Lease - Mira Mesa/Miramar

Located in the sought-after Sorrento Mesa submarket, 6335 Ferris Square provides highly functional flex and laboratory space designed for life sciences and technology users. The property offers approximately 70% lab build-out and 30% office space, combined with full climate control, wet lab infrastructure, and enhanced HVAC systems to meet specialized operational needs. Existing improvements include fume hoods, chemical and hazardous material zones, a tissue culture suite, and dedicated shipping and receiving areas. Tenants benefit from a quiet, campus-like setting within a well-established biotech corridor, surrounded by a robust network of life science companies. Accessibility is a key strength, with immediate reach to Interstates 805, 5, and 15, ensuring strong regional connectivity. On-site, two grade-level doors and ample parking support logistical ease and convenience. Positioned within minutes of coastal amenities and regional thoroughfares, the property accommodates R&D, tech operations, and hybrid lab-office configurations for businesses focused on innovation and growth.

Date on Market:

2025-09-23