461 Life Science Properties for Lease in California, USA

Valencia Industrial for Lease - Santa Clarita Valley

Located in the business-friendly Santa Clarita Valley, 29120 Commerce Center Drive features numerous state-of-the-art Class A amenities. This freestanding facility offers 134,705 square feet of manufacturing space complemented by 10,202 square feet of office area, with extensive exterior and interior renovations recently completed, enhancing both functionality and presentation. Industrial specifications include a 30-foot minimum clear height, two ground-level doors, 20 dock-high doors, new HVAC systems, K-25 ESFR sprinklers, and 1,600 amps, 277/480-volt, 3-phase, 4-wire power. The property also offers efficient truck maneuvering and ample vehicle storage, with over 230 parking spaces, including 224 standard stalls and seven accessible spaces. Situated within the Thirty Mile Zone (TMZ), the facility is surrounded by a strong concentration of film, production, and studio users. Immediate access to Interstate 5, Highway 126, and Interstate 210 allows for seamless connectivity throughout Southern California, while a wide range of nearby dining, retail, and service amenities enhances convenience for the workforce. The Santa Clarita Valley remains a premier business destination, attracting major employers such as Advanced Bionics, ITT Aerospace, Sunkist, and Logix. The region’s pro-business environment is supported by incentives, including tax credit programs, film and television production credits, research and development tax benefits, and workforce resources through the WorkSource Center.

Date on Market:

2025-03-13

San Marcos Industrial for Lease

1617 Capalina Road delivers an impactful flex facility with abundant parking and a strategic location just off Highway 78 in San Marcos, California. Offering up to 24,000 square feet of well-equipped space for immediate occupancy, this exciting opportunity provides an ideal solution for wholesalers, retail showrooms, contractors, gyms and much more. The available space provides flexible demising options beginning at 8,500 square feet, allowing both emerging and established businesses to find their perfect space. 1617 Capalina Road delivers quality specs and features that support operational efficiency and performance, including a complete HVAC system. The space is equipped with robust loading infrastructure, including a loading dock with a truck well, a grade-level loading door, and an ~25-foot interior clear height, allowing for streamlined loading, unloading, and product storage. A dependable power supply providing 400 amps of 102-208 volts or an option for 277-480 volts supports operations. A highly visible location directly off Highway 78 ensures both exposure and accessibility for businesses at 1617 Capalina Road. Prime frontage to the highway allows building signage to be seen by more than 140,000 passing vehicles daily, enhancing brand positioning in the local market. The highway also seamlessly connects the location with both the 5 and 15 Freeways in just 10 to 15 minutes, enabling swift access for regional customers and commuters. This prime location improves convenience for employees, with proximity to a wide selection of grocery, retail, restaurants, and service amenities. The available space is offered on NNN lease terms. Heavy uses, discretionary permitting, and additional parking requirements will increase the rental rate. To schedule a tour and find additional details, contact the MIRA Commercial Real Estate team today.

Property Type:

Flex

Date on Market:

2026-03-20

San Diego Flex for Lease - Kearny Mesa

Exceptional opportunity to lease a highly improved freestanding building of 56,159 square feet in the most strategic location in all of San Diego, located in the heart of Kearny Mesa. Providing exceptional freeway and surface street access, this facility logistically from a business and quality of life perspective, is a home run. 4650 Overland Avenue is perfect for any flex, R&D, life science, lab, medical, and precision manufacturing applications. The interior has a mix of lab space, clean rooms, conference, private offices, open-plan bullpen areas, kitchen/lunchroom/lounge section, patios, and skylights. The warehouse space has numerous dock loading doors, great clear height, locker rooms, and showers. With a very distinctive architecture, this property creates an exceptional client and employee experience and energy that is unique and in a class of its own. All of this is supported by a robust HVAC and distribution system, multiple floor drains, waterlines, fully sprinklered areas, a backup diesel generator, a significant gas and air network, and a 4,000-amp, 277/480-volt power capacity, which can be cost-effectively expanded due to prior infrastructure preparation. The entire property can easily be enclosed, and a conduit is in place to install security gates. 4650 Overland Avenue is situated within the Spectrum Center, a very walkable and upscale neighborhood with a significant array of amenities within minutes. Multiple throughfares are proximate to the facility, including Interstates 15, 8, and 805, as well as the 163 and 52 freeways, which route into San Diego within a five-minute drive and extend into the Inland Empire and Los Angeles in under two hours. For easy connections to international and domestic markets, the San Diego International Airport is only 9.2 miles away. Don't miss out on a one-of-a-kind facility that can serve any manufacturing or distribution business long into the future, offering critical in-place infrastructure and flexible interior configurations that allow a business to scale and grow with its evolving operational requirements. This opportunity is perfect for an owner/user who is looking to expand their operation into a showstopping space.

Date on Market:

2025-05-01

San Francisco Industrial for Lease - Bayview/Hunters Point

1409 Egbert Ave is a modern, multi-tenant industrial facility located in San Francisco’s Bayview neighborhood, constructed in 2021 to support a wide range of light industrial and creative uses. The building features customizable space with soaring 18-foot ceilings, large industrial-grade windows that provide abundant natural light, and wide access points suitable for loading and vehicle maneuvering. Zoned PDR-1 and PDR-2, the property is equipped with robust infrastructure including 3-phase power (600 Amp), heavy-duty electrical systems, high-speed internet, and an ESFR sprinkler system for enhanced fire protection. Tenants benefit from 24/7 secure access, dedicated restrooms, a shared lobby entryway, and convenient street parking. Strategically positioned near I-280, US-101, and public transit, the location offers seamless connectivity to SOMA, downtown San Francisco, and the broader Bay Area business ecosystem.

Date on Market:

2025-10-17

South San Francisco Industrial for Lease

Experience logistics simplified at our South San Francisco Harris location. This flexible warehouse space features all the amenities your business needs to thrive, with units ranging from small to large configurations to accommodate businesses of all sizes. Strategically positioned with easy access to major transportation networks including I-101, I-280, and I-380, this location is just 5 minutes from San Francisco International Airport (SFO) and offers excellent proximity to Caltrain. Security and convenience come standard with 24/7 facility access, private secure units, well-lit pathways, building access control, video surveillance, and comprehensive visitor management systems.

Date on Market:

2021-03-11

Beverly Hills Office/Medical, Office/Retail for Lease

Prestigious Beverly Hills address in proximity to dining, hotels and shopping. Variety of excellent amenities within walking distance. Suites divisible down to ± 1,800 RSF - ideal for mental health/therapy use. Building top signage available. Highly visible trophy location. Ideal floor plates for a variety of uses. Large balconies on every floor. Medical use by-right approved on 2nd and 3rd floors. Excellent parking with over 120 spaces available. Property management and security on-site. Convenient access to Freeways. Complimentary parking for visitors. Janitorial service 5 days/week.

Date on Market:

2021-04-27

San Leandro Multiple Space Uses for Lease

Proud of its labor roots in the 1950s as a Dodge automobile manufacturing plant, Gate510 at 1933 Davis Street currently offers a variety of unique spaces from 1,000 to 10,000 square feet of factory-raw, office-finished, or build-to-suit units. Amenities at this R&D facility include a community conference room, EV charging, pet storage, freight and passenger elevators, and an on-site recycling program. Tenants at Gate510 can utilize features such as shared loading docks, a robust HVAC system, heavy power, chemical fume hoods, lab sinks, safety showers, compressed air, gigabit fiber internet, and USPS, FedEx, and UPS drop boxes on-site. Users will find a ground-floor retail hub with easy access to shops, supplies, dining materials, on-site property management, and shared conference rooms. Five minutes from Oakland International Airport, Gate510 serves a global community of large-scale artists, tech, and makers with easy BART access, free parking, and 24-hour on-site security. Users enjoy the convenience of being located off Interstate 880, which connects to the Oakland International Airport and BART 1 mile away. Set up shop at Gate510, a state-of-the-art R&D campus with a proven track record and tenant expansion success stories in breathtaking San Leandro, California.

Date on Market:

2025-03-05

Santa Ana Office/Medical for Lease

Property Type:

Office

Date on Market:

2025-10-31

Watsonville Flex for Lease

94 Hangar Way is a 9295sqft+/- Light Industrial/Flex building located on the corner of Hangar Way and Anna St next to the Watsonville Hospital with quick access to Highway 1. The building has ample power, ample private parking, tons of warehouse space, private offices, private restrooms, shower facilities, lab room space, breakroom space, natural light, and new renovations throughout. Building and monument signage available. Modified Gross Lease. Walkable to hospital, gym, bus line, dining.

Date on Market:

2026-06-15

Suisun City Flex for Lease - Fairfield/Suisun City

Date on Market:

2026-06-12

Auburn Office/Medical for Lease - Auburn/Lincoln

Property Type:

Office

Date on Market:

2026-06-08

San Francisco Office for Lease - MidMarket

The property at 982 Mission Street in San Francisco is a four-story office building with a basement, built in 1924. It offers approximately 47,067 square feet of space and includes secured access systems, elevator service, and a roll-up door from Jessie Street. Located within the SoMa district near Market Street, the building is adjacent to major transit routes and public transportation, including local bus lines and BART stations. The surrounding area consists of mixed-use development with retail, office, and residential properties, contributing to heavy pedestrian traffic and accessibility.

Date on Market:

2026-06-08

Irvine Flex for Lease - Irvine Spectrum

6 Thomas is a Class A life science facility located within the Irvine Spectrum submarket, offering a highly functional configuration suitable for research, laboratory, and production users. The property consists of approximately 31,375 square feet situated on an estimated 1.49-acre parcel, with a balanced allocation of lab/production and office space. The building includes roughly 12,000 square feet of lab/production area complemented by approximately 16,000 square feet of office space, supporting a wide range of life science, biotech, and advanced manufacturing operations. The improvements also include a warehouse component (~2,400 SF) and one grade-level loading door, providing operational flexibility for light industrial and distribution needs. The site is equipped with approximately 87 parking spaces (3.0 per 1,000 SF), supporting employee-intensive uses. Interior layouts feature a mix of open office areas, private offices, production rooms, and lab space across two floors, allowing for both administrative and technical workflows within a single asset. Located in Irvine’s established business and technology hub, the property benefits from proximity to major thoroughfares including Alton Parkway, Jamboree Road, and the I-405, providing regional accessibility throughout Orange County.

Date on Market:

2026-06-03

Irvine Office/Medical for Lease - Irvine Spectrum

Office Space Available for Sublease – 22 Odyssey, Suite 135, Irvine, CA Located in the heart of Irvine’s highly sought-after business corridor, Suite 135 at 22 Odyssey offers a professional and efficient open concept office environment ideal for a growing business. The 1500 square foot space features a well-maintained open floor plan perfectly designed for its current use as a pharmacy with client-facing operations within a prestigious Irvine business setting. This professionally appointed suite provides a welcoming atmosphere with quality finishes, functional workspace configurations, and convenient access to major transportation routes including the I-405 and I-5 freeways. Situated a block from Hoag Hospital and near the Irvine Spectrum, John Wayne Airport, and a wide range of dining, retail, and business amenities, the location offers exceptional convenience for employees and patients alike. Key features may include: Professional reception or entry area Open workspace High-speed internet and telecommunications readiness Ample parking availability Move-in ready condition Convenient ground-floor access The property is positioned within a well-managed commercial campus that provides a polished corporate image while maintaining accessibility and flexibility for day-to-day business operations. This sublease opportunity presents an excellent option for businesses seeking a turnkey Irvine Pharmacy or Medical Office location with favorable terms and immediate availability.

Property Type:

Office

Date on Market:

2026-05-29

Mission Hills Office/Medical for Lease - Eastern SFV

14901 Rinaldi Street is a three-story, Class B office building constructed in 1993 on a 2.04-acre parcel in Mission Hills, California. The building encompasses 52,320 square feet and is designed for medical office use. It offers central air conditioning, paved surface parking, and controlled access. The location provides access to primary regional transportation routes including Interstates 405 and 5 and State Route 118. The surrounding area includes healthcare facilities, retail services, and dining establishments.

Property Type:

Office

Date on Market:

2026-05-27

Santa Ana Office for Lease - Parkcenter Area

For Lease | Medical Office Space 550 N. Golden Circle Dr. Suite A, Santa Ana, CA Professional medical office suite available for lease in a well-maintained and conveniently located medical/professional office setting in the heart of Santa Ana. Suite A offers an efficient layout ideal for business, medical, dental, wellness, therapy, chiropractic, or other healthcare-related practices. Property features include a welcoming reception area, private exam or consultation rooms, administrative office space, and ample on-site parking for patients and staff. The location provides excellent accessibility with close proximity to major freeways, retail amenities, restaurants, and surrounding medical services. Highlights include: • Move-in ready medical office suite • Functional layout for healthcare users • Reception and waiting area • Multiple private offices/exam rooms • Ample parking • High visibility and convenient access • Centrally located near the 5, 55, and 22 Freeways • Suitable for medical, dental, therapy, chiropractic, and professional office use Ideal opportunity for healthcare professionals seeking a professional environment in a strong Orange County location.

Date on Market:

2026-05-26

Torrance Flex for Lease - 190th Street Corridor

Sublease $1.50 per SF Gross (Tenant pays Electricity/Wi-Fi) Would consider leasing (office only/warehouse only): Pricing Negotiable ($TBD) Space description: SF: 4,800 See attached floor plan 5 offices, 1 conference, 1 lobby, 2 restrooms, 1 modular lab space, 1 warehouse area Roughly 45% office / 55% warehouse Lease: Sublease is 9 Months. Term ends in March 31, 2027. *Direct Lease is available - Landlord is open to renew the lease for another 12 months afterwards*

Date on Market:

2026-05-26

Foothill Ranch Flex for Lease - Lake Forest/Foothill Ranch

7,477 sq. ft. building • 4,002 sq. ft. of office space • 1,200 sq. ft. of lab/assembly/testing area • Energy-efficient industrial facility with on-site solar • Freestanding building • High image • 3:1 parking • Two (2) ground level doors • Fire sprinklered • Easy access to 241 Foothill Transportion Corridor

Date on Market:

2026-05-22

Petaluma Office for Lease - Petaluma/Cotati/Rohnert

Best North Petaluma location with direct access to Highway 101 and immediately adjacent to the Redwood Business Park. Strategically located between Santa Rosa, Marin County, and the Sonoma Wine Country, the property is surrounded by a variety of amenities including Redwood Gateway Shopping Center (Kohls Anchor), Lagunitas Brewing, Home2Suites (Hilton), and an abundance of shops and restaurants. Less than one mile from SMART.

Date on Market:

2026-05-15

San Diego Office for Lease - Rancho Bernardo

Property Type:

Flex

Date on Market:

2026-05-14

San Diego Industrial for Lease - Sorrento Valley

Date on Market:

2026-05-11

Pomona Industrial for Lease - Eastern SGV

Date on Market:

2026-05-07

Diamond Bar Industrial for Lease - Eastern SGV

Excellent opportunity to lease a well-maintained industrial property in the City of Diamond Bar. This +-29,557 SF space is located in the M1.5 Light Manufacturing zone and is suitable for a variety of uses including manufacturing, warehousing, distribution, research and development, and related operations. The building features approximately 33.6% office buildouts, providing a functional balance between office and warehouse space. Warehouse area offers approximately both 17-foot and 19 foot clearance areas, along with both dock-high and grade-level loading to support efficient operations. There are 3 functional loading docks. The property is constructed with durable concrete tilt-up construction and is sprinklered. Power capacity includes 400 amps, 277/480V, 3-phase, 4-wire service, suitable for a wide range of industrial and commercial applications. The site offers an estimated 45 parking spaces, subject to tenant use. 1 large conference room, multiple private office spaces, restrooms, storage rooms, and private room with shower included. Separate mens and womens bathrooms with multiple stalls in each bathroom. Conveniently located with access to major freeways, the property provides strong connectivity to surrounding commercial and industrial hubs. Lease rate is $1.50 per SF per month. Tenant will be responsible for all utilities and interior and exterior maintenance such as yard maintenance. Also, tenant needs to pay their own liability insurance and workman’s comp. Owner reserves approximately 363 SF for private use which is already excluded from the listed SF.

Date on Market:

2026-05-05

Irvine Flex for Lease - Irvine/Tustin Legacy

Date on Market:

2026-05-04