178 Life Science Properties for Lease in Massachusetts, USA

Woburn Flex for Lease - Burlington/Woburn

25-K Suite 700: Incubator Lab Space – Ideal for Startup companies seeking a mini full-service lab with essential infrastructure already in place; Perfect for biotech startups, incubator programs, and small R&D teams looking for a turnkey lab solution. Support entrepreneurs, startups, and small business owners as they launch and grow their ventures. Includes: 8' Fume Hood with dedicated make-up air and exhaust; Bio Safety Cabinet; Lab Sink with point-of-use acid neutralization tank; Benchwork for research and development; Eyewash Station for lab safety compliance; Gas Connection for lab operations.

Date on Market:

2025-03-03

Westford Office for Lease - Concord/Maynard

ABG Commercial is thrilled to present 314 Littleton Road, a premier 175,000 SF R&D building available for lease. With Red Hat set to vacate in May 2025, this offers the new lessee the chance to capitalize on the property’s exceptional features, such as 7000A of power, 13’ clear heights, efficient floor plates, and ample parking (3.6 per 1,000 SF). Strategically located within two miles of Interstate 495, this property provides swift access to Greater Boston’s highway system. Situated in the heart of Westford Technology Park, the building is surrounded by major corporate tenants, offering a rare opportunity to secure a best-in-class facility with robust infrastructure.

Date on Market:

2025-02-19

Cambridge Retail for Lease - Mid-Cambridge/Harvard Sq

This fully equipped restaurant and bar includes 40 beer taps, a beer cooler with storage for 40 kegs, high-speed kiddie exhaust system,and a grease trap. A complete list of equipment is available upon request Storage:The facility has a walk-in refrigerator and freezer located in the basement. *Liquor License: Full liquor license issued by the City of Cambridge. Seating Capacity: The establishment can accommodate 99 diners plus bar seating Location: The restaurant is located in the Restaurant Hub of Cambridge, specifically in Inman Square, which is in close proximity to MIT and Harvard University. Nearby Amenities and Restaurants: - Christina’s Homemade Ice Cream - All Star Sandwich Bar - All Star Pizza Bar - Inman Square Wine & Spirits - Casa Portugal Restaurant - Puritan Oyster Bar - Oak Bistro - Christina’s Spice & Specialty Foods - East Cambridge Savings Bank - The Druid - CHA Cambridge Hospital - And many more. **Operational History:** The property has been grandfathered as a restaurant since 1986. Parking: There are 4 on-site parking spaces available, with additional parking options nearby after 5:00 PM. Loading Area: The loading area is located in the parking lot. Traffic Count: Approximately 22,358 vehicles pass through the intersection of Cambridge and Prospect Streets daily. **Utilities: The property has separately metered utilities for electricity, water, and gas. Water & Sewer Services: These services are provided by the City of Cambridge.

Date on Market:

2025-01-24

Waltham Industrial for Lease

Versatile commercial/industrial space for lease in Waltham. The property contains over 14K RSF on two levels, which is currently demised for two tenants or can be combined for a single user. Both levels can accommodate a variety of commercial, industrial, manufacturing and/or warehousing needs. The building contains a double wide exterior loading dock and a small overhead door on the opposite side of the property. The building is fully sprinklered and air conditioned on both levels and offers 15+ parking spaces. Flexible rents and lease terms available. Please see attached flyer for additional information!

Date on Market:

2024-12-13

Ashland Flex for Lease - Hopkinton/Holliston

159 Chestnut Street in Ashland, MA, is a 21,600+/- flex building that boasts an adaptable layout and can accommodate a variety of uses from R&D to light distribution and more. Located in the heart of Ashland, Massachusetts, with convenient access to major routes like the Massachusetts Turnpike (I- 90), Routes 126 and 135, this spot offers excellent connectivity to Boston and nearby MetroWest towns, making it ideal for both local and commuting professionals.

Date on Market:

2024-10-09

Billerica Office, Flex for Lease - Lowell/Chelmsford

700 & 900 Technology Park Drive presents a multi-tenant office property within Billerica, Massachusetts’ well-established Technology Park master-planned development. The park offers space ideally suited for lab, light manufacturing, research and development (R&D), and professional office use. Key property features include ample surface parking, up to 13-foot ceiling heights, a loading dock, and passenger elevator service. Responsive, professional property management is also on hand to meet all tenant needs. Fully built-out, second-floor space is available at 900 Technology Park Drive. Tenants experience an efficiently designed work environment that receives plentiful natural light throughout the day. Technology Park is a 70-acre master-planned development with 1.22 million square feet of space in a tranquil suburban setting. Tenants enjoy easy highway accessibility as the property sits directly off Route 3 and a short distance from Route 128 and Interstate 93. The property is strategically located 25 miles northwest of Downtown Boston, making it ideal for businesses seeking a convenient yet calm work environment.

Date on Market:

2025-11-19

Worcester Flex for Lease - Worcester Metro

HIGHLIGHTS - Industrial/Research and Development/Flex Space LED Lighting, Air Conditioning and Gas Heat, High Ceilings, Lots of Parking, Easy Highway Access Beautiful Entrance in Front, Drive-in Door, and Loading Dock in Rear PROPERTY OVERVIEW - 4,600 SQUARE FEET of MODERN SPACE FOR RESEARCH AND DEVELOPMENT, MANUFACTURING, or OTHER TYPES OF BUSINESS 4,600 Sq Ft. Rent and CAM is $5,900. Yes! $5,900 includes rent and CAM. You only pay for gas, electricity, internet, and water/sewerage. Armory Business Center is a building comprising modern workspaces. Strategically located, Armory Business Center is approximately one-half mile from Worcester's central business district and near several major highways, including Route 146, Interstate 290, and the Mass Turnpike. Armory Business Center Features the Following: 22' minimum height ceilings Clear span interiors High PSI cement floors LED lighting in the office and production areas Natural gas heat Three phase electric ADA-accessible bathrooms in each suite Kitchenette with dishwasher Attractive black stone front on the building Backlit LED signage for each suite Private entrance in the front of building Loading dock and drive in door in rear Lots of parking High-speed internet access available Central air conditioning Well insulated - It's new All units are ready for clean rooms too For more information contact us

Property Type:

Industrial

Date on Market:

2025-09-25

Haverhill Office, Flex for Lease - Lawrence/Andover

Located in Haverhill’s Historic Downtown area within walking distance to many restaurants and shops. 143 Essex Street is an eight-story commercial building with dynamic spaces, immediate access to the commuter line Haverhill, North station, and I495. The mixed use spaces are perfect for small businesses or storage needs. Loading dock and freight elevator allow for easy access to spaces. Parking available on site.

Date on Market:

2025-11-20

Woburn Office for Lease - Burlington/Woburn

Suite 3600: 3 Months' rent abatement. Approx 5,210 SF Short-term Sublease; Headquarters or Satellite Office / Showroom in high image and highly visible building; open areas with workstations, conference/meeting rooms, private offices, kitchen/breakroom. Lessee-Subsidized & Direct Lease available with Owner.

Date on Market:

2024-01-01

Watertown Office for Lease

One of a kind warehouse/office hybrid space. Newton/Watertown line. Garden level. Needs cosmetics but well worth it at this price. Heat and hot water included. Perfect for light industrial, kinder garden, after school, office, etc. 7 parking can be included in rent. Don't miss this! Right off the mass pike highway. In the zone of major biotech development in Watertown Sq. Hard to find a better location or price in this prime area.

Date on Market:

2023-12-28

Leicester Multiple Space Uses for Lease - Outlying Worcester

75,000 +- SF former industrial mill building on a major east-west corridor in Worcester County. Highly visible and easily accessible for various uses, including office, retail, and distribution. Sub dividable space; available SF between 500 - 75,000, competitive rates, flexible lease terms, ample acreage for truck access, and potential truck offloading. Located on Route 9 in the Cherry Valley section of Leicester, MA, just over the Worcester City Line.

Date on Market:

2025-12-01

Worcester Office/Medical for Lease - Worcester Metro

Kelleher & Sadowsky is pleased to present 25,533 square feet of high-quality office space available immediately for sublease at 306 Belmont Street in Worcester, MA. Formerly occupied by UMass Memorial Health, the space is in excellent condition and features a versatile layout that includes a mix of private offices, open work areas, training and conference rooms, and access to building amenities. Select furnishings may be available as part of the sublease. Ideally situated on Route 9 with quick access to I-290, 306 Belmont Street offers exceptional connectivity to the region’s colleges, hospitals, and surrounding com-munities. The property is located directly across from UMass Memorial’s University Campus, AbbVie’s bio-research facility, and The Reactory — Worcester’s rapidly developing biotech park. Don’t miss the opportunity to establish your presence in the heart of Worcester’s thriving life sciences and bio-tech corridor. Contact us today to schedule a tour.

Property Type:

Office

Date on Market:

2023-09-18

Bedford Office for Lease - Concord/Maynard

Rent is full service gross including utilities, net of interior cleaning. Presently available for lease is 1,545 - 15,000 +/- SF of first and second floor office/flex space. Situated with IND-B zoning, 4 Preston Court is strategically positioned near Hartwell Avenue in Lexington, MA. 4 Preston stands as a recently renovated office/flex building, showcasing ample surface parking at a ratio of 3.64 spaces per 1,000 square feet, equipped with a passenger/freight elevator capable of handling up to 4,500 lbs, and featuring contemporary common areas. Noteworthy neighbors encompass prominent entities such as Thermo Fisher Scientific, Stoke, Diversified Technologies, Cubic PV, and UCB. Within a 3-mile radius of the property, a workforce of 16,053 white-collar professionals thrives, contributing to a rich talent pool while enjoying proximity to some of Boston's most affluent suburbs. Encircled by conservation land, the property lies adjacent to the Minuteman Bike Path and Hanscom Air Force Base, with convenient accessibility to Routes 3, 128, and 225.

Date on Market:

2025-01-09

Cambridge Flex for Lease - E Cambridge/Kendall Sq

Property Type:

Industrial

Date on Market:

2022-07-18

Marlborough Office, Flex for Lease

313 Boston Post Road is a first class, two-story building located along Route 20 in Marlborough, MA. The 76,322 SF property is perfectly positioned in the MetroWest market between Routes I-495, I-290 and I-90/Mass Pike. Tenants will enjoy convenient access to all area highways and proximity to a wealth of restaurants and retail stores. The building offers flexible floor plates and a state-of-the-art environment for its tenants, complete with a two-story atrium lobby and fitness center.

Date on Market:

2025-08-21

Framingham Office, Industrial for Lease - Framingham/Natick

Strategically situated in Downtown Framingham, The Offices at Dennison Triangle, located at 39 Grant Street, offers completely renovated office space in a vibrant Boston suburb. The recent renovations include all-new building systems and ideal layouts for small lab space and general office users, with suites starting at 500 square feet. Businesses can customize their space to their liking since most buildout costs will be included in the rental rate. Features at 39 Grant Street include underground parking, 13-foot high ceilings with 10-foot mahogany windows for abundant natural light, two passenger elevators, one freight elevator, exposed ceilings, and designs for heavy floor loads. The property is very walkable, surrounded by popular breweries, shops, dining spots, and neighborhood amenities. It is also just a half-mile walk to the Framingham Commuter Rail Station and a short drive to Worcester Road and the Massachusetts Turnpike/I-90. The Logan International Airport is less than 40 minutes away for business travel needs. Given the convenience to transit and major transportation routes, businesses enjoy access to a significant potential workforce.

Date on Market:

2025-09-08

Framingham Office, Flex for Lease - Framingham/Natick

1 Grant Street is a historic building located in the heart of the Framingham neighborhood in Framingham, MA. This property features five floors of office and lab space and totals about 75,000 square feet. This building is conveniently located within a three-minute walk to MBTA Commuter rail to Boston/Worcester. Ample parking in both surface and covered spaces are readily available and the building is located next door to popular establishments including Jacks Abby and Springdale Brewery. The lobby and courtyard have recently gone through renovations providing a high-class tenant experience.

Date on Market:

2025-09-08

Marlborough Office for Lease

Marlboro Executive Park at 65 Boston Post Road W is near Route 20 in Marlborough, Massachusetts. This office building features a ribbon glass exterior and a three-story, rounded glass wall with floor-to-ceiling windows that flood interior stairwells with natural light. The property includes two passenger elevators, 240 surface parking spaces, and 277/480-volt, 1200-amp electricity. Benefit from efficient floorplates allowing suite layout changes to best suit tenant needs. Marlboro Executive Park offers secure keycard access, new bathrooms, and waterless environmental technology. The property is surrounded by abundant amenities with multiple shopping centers within a 10-minute walk, offering shopping, dining, entertainment, and personal services. A small city with plenty to offer, Marlborough is ideally situated along the Massachusetts Innovation Corridor and is considered a premier business destination and a regional biotech hub. The city's progressive management, pro-business administration, and well-maintained infrastructure have attracted some of the region's largest employers, including GE Healthcare, Quest Diagnostics, Raytheon, Hologic, Sunovion Pharmaceuticals, Ken's Foods, and SanDisk. Marlborough is also home to the New England Sports Center and hosts New England's largest Labor Day parade. Employers have direct access to a highly skilled workforce with leading higher education institutions, such as Harvard University and Massachusetts Institute of Technology, only 40 minutes away. Marlboro Executive Park sits a half-mile from the I-495 and Route 20 intersection, allowing immediate access to nearby markets throughout Massachusetts.

Date on Market:

2025-07-08

Waltham Office for Lease

204 2nd Avenue is a multi-tenant office building with wide range of tenants from startups to biotech. The Building is conveniently located in Waltham directly off the Route 95 Exit 27B with freeway visibility and signage opportunities. Opportunity to lease office space within the four story professional building. Sure to meet all your business needs. For additional information contact property owner, Brett Marley.

Date on Market:

2025-08-07

Chelmsford Office for Lease - Lowell/Chelmsford

This is an Office/R&D/Medical building offering: Power- 3PH, 1200 AMPs, 208V/108V, ceiling height- office: 8'11 inch, R&D: 12', windows- tinted with vertical blinds throughout, HVAC- 17 individual electric a/c units. 5 single zone gas fired roof heating units.First Floor: 26 offices, 2 conference rooms, a cafeteria area, and lobby. Second Floor: R&D finish, 2,500 SF raised computer floor and open space throughout the remaining space built-out with finished ceiling only. Meticulous landscaping. Property is located at the exit ramp from RT 129 onto RT 3 S. Only 1 mile from the RT 3/ RT 495 interchange.

Date on Market:

2025-02-06

Lowell Office, Flex for Lease - Lowell/Chelmsford

Date on Market:

2025-10-14

Pittsfield Office for Lease

First class renovated four story office building located in downtown Pittsfield, MA. Located next to the downtown municipal parking garage, one block from downtown Pittsfield.

Date on Market:

2024-12-17

Malden Office for Lease - Medford/Malden

Date on Market:

2025-11-17

Marlborough Retail for Lease

BLACKLINE Retail Group, LLC has been retained by the Owner, on an exclusive basis, to lease 57 Main Street in Marlborough, MA. Prime downtown Marlborough development featuring 92 units, 3,000 SF of retail, and a landscaped courtyard. Just five minutes from I-495, the property enjoys exceptional accessibility and visibility within one of Greater Boston’s largest employment hubs—home to leading technology, life science, and manufacturing companies. Its central location and mixed-use design make it an ideal destination for retailers seeking a vibrant, high-traffic setting in a rapidly growing downtown corridor.

Property Type:

Multifamily

Date on Market:

2025-11-05