189 Life Science Properties for Lease in Massachusetts, USA

Marlborough Retail for Lease

BLACKLINE Retail Group, LLC has been retained by the Owner, on an exclusive basis, to lease 57 Main Street in Marlborough, MA. Prime downtown Marlborough development featuring 92 units, 3,300 SF of retail, and a landscaped courtyard. Just five minutes from I-495, the property enjoys exceptional accessibility and visibility within one of Greater Boston’s largest employment hubs—home to leading technology, life science, and manufacturing companies. Its central location and mixed-use design make it an ideal destination for retailers seeking a vibrant, high-traffic setting in a rapidly growing downtown corridor.

Property Type:

Multifamily

Date on Market:

2025-11-05

Hopkinton Office, Flex for Lease - Hopkinton/Holliston

Date on Market:

2025-10-30

Needham Office for Lease - Wellesley/Needham

Date on Market:

2026-04-21

Natick Office for Lease - Framingham/Natick

Property Type:

Flex

Date on Market:

2025-10-20

Methuen Industrial for Lease - Lawrence/Andover

Date on Market:

2025-10-07

Boston Office for Lease - Seaport

Date on Market:

2025-11-20

Methuen Industrial for Lease - Lawrence/Andover

? Brand-new Class A industrial facility delivering modern specifications in a highly functional, distribution-oriented layout ? ±147,840 SF total building size, designed to accommodate warehouse, logistics, and light manufacturing users ? Tilt-up concrete construction with a clean, efficient footprint and scalable interior configuration ? Currently offering two ±40,000 SF spaces, with the ability to combine for up to ±80,000 SF ? Strategically positioned in Methuen with strong highway connectivity supporting regional and Greater Boston operations

Date on Market:

2026-01-07

Boston Office, Retail for Lease - Seaport

Positioned in the heart of Boston’s Seaport Innovation District, 7 Channel Center presents a premier opportunity within the established Channel Center Planned Development Area. Surrounded by world-class companies, cultural amenities, and new development, the property is strategically located in one of Boston’s fastest-growing submarkets, driven by strong demand across office, life science, and residential sector

Date on Market:

2025-08-12

Boston Flex for Lease - Seaport

Date on Market:

2025-08-08

Lawrence Multiple Space Uses for Lease - Lawrence/Andover

The Riverwalk Innovation District in Lawrence, Massachusetts, offers a rare opportunity to lease fully renovated office, flex, medical, manufacturing, and retail space. As Merrimack Valley's premier mixed-use campus, the historic 3.5 million-square-foot complex blends 19th-century mill architecture, including exposed wood beams, exposed brick details, and soaring interiors, with modern finishes, such as upgraded lighting, HVAC, restrooms, and break areas. The Pavilion provides ready-to-go and build-to-suit space options for businesses of all sizes, from boutique offices to large institutional tenants, with flexible lease terms available. Located directly off Interstate 495 and adjacent to the Lawrence MBTA Commuter Rail, The Pavilion offers exceptional accessibility and a dynamic, amenity-rich environment. Tenants enjoy a mix of on-site dining, retail, banking, fitness facilities, a full athletic field, child care, waterfront restaurants with patio seating, and a underground parking garage with over 1,250 spaces. Outdoor green space, beautiful river views, and a true live-work-play atmosphere create a standout environment for growth and innovation. Join leading companies and prominent retailers at The Pavilion and capitalize on a premier campus that combines historic character, modern amenities, and unmatched convenience.

Date on Market:

2026-04-02

Cambridge Office for Lease - E Cambridge/Kendall Sq

Full building lab conversion completed in 2022, offering early stage biotech companies ready to go lab suites.

Date on Market:

2025-08-27

Newton Office for Lease - Newton/Brookline

Date on Market:

2026-03-23

Hopkinton Coworking for Lease - Hopkinton/Holliston

Discover premium office space in our Elmwood Park building in Hopkinton, Massachusetts. Choose a location favored by several Fortune 500 companies in a state that came 15th in a CNBC survey to find the“Top States for Business” in 2023. Travel easily, with two interstate highways (I-90 and I-495) passing through Hopkinton, ideal for attracting guests from Worcester, Boston, and Providence. Prefer public transport? Southborough Train Station and PriceChopper Hopkinton Bus Stop are 4 mi and 5 mi away, respectively. If you’re expecting clients from further afield, drive 28 mi and greet them at Worcester Regional Airport. Flexible office space awaits to suit you and your guests needs. Get all the business support you need to grow and succeed at Elmwood Park. Whether you’re collaborating in our fully furnished coworking areas, pitching in our quiet meeting rooms, or working solo in our private spaces, our professional offices with business-grade WiFi give you the perfect platform to thrive. After being served a warm welcome from the reception team, enjoy hot barista-style coffee from the onsite café to help keep you in full flow. When it’s time to escape the office, gather your thoughts in our peaceful garden or head to the local gym, parks, museum, theater, or restaurant.

Property Type:

Office

Date on Market:

2025-07-10

Natick Flex for Lease - Framingham/Natick

Property Type:

Industrial

Date on Market:

2025-07-02

Natick Flex for Lease - Framingham/Natick

Date on Market:

2025-07-02

Waltham Flex for Lease

Date on Market:

2025-07-02

Charlestown Flex for Lease - Charlestown/East Boston

Brand New Lab, Heavy R&D, and Clean Room space with ability to modify as needed. Heavy Power, Loading, and other infrastructure available. Perfect space for Light Manufacturing, Electronics, Clean Room, and Advanced Manufacturing Groups.

Date on Market:

2025-05-12

Cambridge Office for Lease - W Cambridge/Alewife

Property Type:

Flex

Date on Market:

2025-05-06

Chicopee Office for Lease - Hampden County

Development Associates is pleased to offer For Lease ± 15,000 SF of Office/Tech/Lab space, available immediately, in Westover Industrial Park in Chicopee, MA.

Property Type:

Specialty

Date on Market:

2025-05-01

Cambridge Office for Lease - E Cambridge/Kendall Sq

Date on Market:

2025-04-02

Worcester Office for Lease - Worcester Metro

One Innovation Drive is a four-story office/laboratory facility with an adjacent single-story parking structure and is known as Building 3 in the UMass Medical & Science Park. Situated alongside the continuously growing UMass Chan Medical School and UMass Memorial Medical Center campus, the UMass Medicine Science Park both contributes to and benefits from the organic synergies created within this interconnected complex. A palpable energy from an unparalleled 10,000+ knowledge seekers on site – in addition to approximately 10 additional neighboring colleges and universities – permeates the campus, encouraging innovative thoughts and collaborative partnerships.

Date on Market:

2026-04-22

Beverly Multiple Space Uses for Lease - Danvers/Beverly

Date on Market:

2026-04-16

Marlborough Office for Lease

KS Labs @293 presents move-in-ready lab and professional office space in the heart of Marlborough, Massachusetts. The office building contains over 200,000 square feet across six floors and is located among numerous MetroWest-based life science companies. Property features include recent renovations and a brand-new amenity center, ensuring a dynamic environment where businesses can innovate and thrive. Enter the building through a sophisticated and natural-light-filled five-story atrium. Tenants have access to a wealth of on-site amenities, such as a full-service café, a conference center, a fitness center with a sauna, daycare services, storage space, and access to rooftop decks. Immediately available lab spec suites offer 39 lab benches, three 6-foot fume hoods with the capacity to add more, a freezer room, dedicated 300-amp/480-volt electric service, and under-sink chip tanks for chemical neutralization. Plus, capitalize on an efficient layout with a reception area, open office space, multiple lab zones, a freezer room, a kitchen/break room, and more. KS Labs @293 is within minutes of the newly opened Apex Center, New England’s largest multi-experience events and entertainment venue. Other surrounding amenities include hotels, retail stores, and restaurants like 110 Grill and Okami. RK Centre, a Hannaford supermarket-anchored regional shopping center, and the 225-unit luxury Talia Apartments are directly adjacent to this best-in-class property. KS Labs @293 is less than a quarter-mile from the recently expanded Route 20, within a mile of Interstate 290, 3 miles to Route 9, and within 4 miles of the Massachusetts Turnpike.

Date on Market:

2026-01-14

Watertown Office for Lease

GMP space available for sublease- 4 ISO clean room suites. Fully furnished.

Date on Market:

2024-12-30