188 Life Science Properties for Lease in Massachusetts, USA

Boston Flex for Lease - Seaport

Date on Market:

2025-08-08

Lawrence Multiple Space Uses for Lease - Lawrence/Andover

The Riverwalk Innovation District in Lawrence, Massachusetts, offers a rare opportunity to lease fully renovated office, flex, medical, manufacturing, and retail space. As Merrimack Valley's premier mixed-use campus, the historic 3.5 million-square-foot complex blends 19th-century mill architecture, including exposed wood beams, exposed brick details, and soaring interiors, with modern finishes, such as upgraded lighting, HVAC, restrooms, and break areas. The Pavilion provides ready-to-go and build-to-suit space options for businesses of all sizes, from boutique offices to large institutional tenants, with flexible lease terms available. Located directly off Interstate 495 and adjacent to the Lawrence MBTA Commuter Rail, The Pavilion offers exceptional accessibility and a dynamic, amenity-rich environment. Tenants enjoy a mix of on-site dining, retail, banking, fitness facilities, a full athletic field, child care, waterfront restaurants with patio seating, and a underground parking garage with over 1,250 spaces. Outdoor green space, beautiful river views, and a true live-work-play atmosphere create a standout environment for growth and innovation. Join leading companies and prominent retailers at The Pavilion and capitalize on a premier campus that combines historic character, modern amenities, and unmatched convenience.

Date on Market:

2026-04-02

Cambridge Office for Lease - E Cambridge/Kendall Sq

Full building lab conversion completed in 2022, offering early stage biotech companies ready to go lab suites.

Date on Market:

2025-08-27

Newton Office for Lease - Newton/Brookline

Date on Market:

2026-03-23

Hopkinton Coworking for Lease - Hopkinton/Holliston

Discover premium office space in our Elmwood Park building in Hopkinton, Massachusetts. Choose a location favored by several Fortune 500 companies in a state that came 15th in a CNBC survey to find the“Top States for Business” in 2023. Travel easily, with two interstate highways (I-90 and I-495) passing through Hopkinton, ideal for attracting guests from Worcester, Boston, and Providence. Prefer public transport? Southborough Train Station and PriceChopper Hopkinton Bus Stop are 4 mi and 5 mi away, respectively. If you’re expecting clients from further afield, drive 28 mi and greet them at Worcester Regional Airport. Flexible office space awaits to suit you and your guests needs. Get all the business support you need to grow and succeed at Elmwood Park. Whether you’re collaborating in our fully furnished coworking areas, pitching in our quiet meeting rooms, or working solo in our private spaces, our professional offices with business-grade WiFi give you the perfect platform to thrive. After being served a warm welcome from the reception team, enjoy hot barista-style coffee from the onsite café to help keep you in full flow. When it’s time to escape the office, gather your thoughts in our peaceful garden or head to the local gym, parks, museum, theater, or restaurant.

Property Type:

Office

Date on Market:

2025-07-10

Natick Flex for Lease - Framingham/Natick

Property Type:

Industrial

Date on Market:

2025-07-02

Natick Flex for Lease - Framingham/Natick

Date on Market:

2025-07-02

Waltham Flex for Lease

Date on Market:

2025-07-02

Watertown Flex for Lease

Located just off Arsenal Street, 200 Dexter Ave is a two-story Class B office building offering 2,240 square feet of flexible office and lab space. Built in 1977, the property features newly renovated interiors, lab equipment, and 54 parking spots. It provides convenient access to major routes including Soldiers Field Road, the Mass Pike (RT 90), and Route 128, and is minutes from downtown Boston, Logan Airport, and Cambridge. Public transit is easily accessible via the nearby #70 bus. The site is also close to shops and restaurants at Arsenal Yards, making it a well-connected and amenity-rich location for businesses.

Property Type:

Office

Date on Market:

2025-09-03

Charlestown Flex for Lease - Charlestown/East Boston

Brand New Lab, Heavy R&D, and Clean Room space with ability to modify as needed. Heavy Power, Loading, and other infrastructure available. Perfect space for Light Manufacturing, Electronics, Clean Room, and Advanced Manufacturing Groups.

Date on Market:

2025-05-12

Cambridge Office for Lease - W Cambridge/Alewife

Property Type:

Flex

Date on Market:

2025-05-06

Chicopee Office for Lease - Hampden County

Development Associates is pleased to offer For Lease ± 15,000 SF of Office/Tech/Lab space, available for occupancy Fall 2025, in Westover Industrial Park in Chicopee, MA.

Property Type:

Specialty

Date on Market:

2025-05-01

Boston Office for Lease - South End

Date on Market:

2025-04-14

Cambridge Office for Lease - E Cambridge/Kendall Sq

Date on Market:

2025-04-02

Worcester Retail for Lease - Worcester Metro

Date on Market:

2025-04-01

Worcester Office for Lease - Worcester Metro

One Innovation Drive is a four-story office/laboratory facility with an adjacent single-story parking structure and is known as Building 3 in the UMass Medical & Science Park. Situated alongside the continuously growing UMass Chan Medical School and UMass Memorial Medical Center campus, the UMass Medicine Science Park both contributes to and benefits from the organic synergies created within this interconnected complex. A palpable energy from an unparalleled 10,000+ knowledge seekers on site – in addition to approximately 10 additional neighboring colleges and universities – permeates the campus, encouraging innovative thoughts and collaborative partnerships.

Date on Market:

2026-04-22

Beverly Multiple Space Uses for Lease - Danvers/Beverly

Date on Market:

2026-04-16

Marlborough Office for Lease

KS Labs @293 presents move-in-ready lab and professional office space in the heart of Marlborough, Massachusetts. The office building contains over 200,000 square feet across six floors and is located among numerous MetroWest-based life science companies. Property features include recent renovations and a brand-new amenity center, ensuring a dynamic environment where businesses can innovate and thrive. Enter the building through a sophisticated and natural-light-filled five-story atrium. Tenants have access to a wealth of on-site amenities, such as a full-service café, a conference center, a fitness center with a sauna, daycare services, storage space, and access to rooftop decks. Immediately available lab spec suites offer 39 lab benches, three 6-foot fume hoods with the capacity to add more, a freezer room, dedicated 300-amp/480-volt electric service, and under-sink chip tanks for chemical neutralization. Plus, capitalize on an efficient layout with a reception area, open office space, multiple lab zones, a freezer room, a kitchen/break room, and more. KS Labs @293 is within minutes of the newly opened Apex Center, New England’s largest multi-experience events and entertainment venue. Other surrounding amenities include hotels, retail stores, and restaurants like 110 Grill and Okami. RK Centre, a Hannaford supermarket-anchored regional shopping center, and the 225-unit luxury Talia Apartments are directly adjacent to this best-in-class property. KS Labs @293 is less than a quarter-mile from the recently expanded Route 20, within a mile of Interstate 290, 3 miles to Route 9, and within 4 miles of the Massachusetts Turnpike.

Date on Market:

2026-01-14

Watertown Office for Lease

GMP space available for sublease- 4 ISO clean room suites. Fully furnished.

Date on Market:

2024-12-30

Boston Office for Lease - Seaport

The IDB is home to makers, designers, architects, communicators, researchers, manufacturers, technologists, innovators and entrepreneurs. The complex’s impressive size allows businesses to grow in place and its interconnected nature fosters an open exchange of information and ideas, creating a uniquely collaborative atmosphere that is highly sought after by its entrepreneurial tenant community

Date on Market:

2024-12-18

Boston Office for Lease - Seaport

10 World Trade is a 555,250 SF, 17-story premier life science and office development in Boston's thriving Seaport District. 10 World Trade will empower, connect, and inspire those who are shaping the future by leading the way in health, wellness, and environmentally sustainable, human-centered design. The development is fully-amenitized with a dramatic 45-foot tall atrium, a 150-seat auditorium built for the exchange of ideas, an indoor/outdoor oasis with operable glass walls, a cultural center with rotating exhibits and activations, and a skyline health club with a 300-meter track and a full suite of fitness offerings. From the eco-friendly redesign of World Trade Center Avenue to smart, energy-saving building features, 10 World Trade is unparalleled in its dedication to sustainability and wellness in a future-proof setting. Certifications include LEED Gold, WELL Gold, SITES Gold, WiredScore Platinum, and SmartScore Certified. 10 World Trade also offers 250 parking spaces at the South Boston Waterfront Transportation Center.

Date on Market:

2024-11-22

Chelmsford Flex for Lease - Lowell/Chelmsford

Date on Market:

2025-07-30

Cambridge Office, Retail for Lease - Mid-Cambridge/Harvard Sq

The Abbot at 18-24 Brattle Street presents a once-in-a-generation opportunity to occupy the most iconic building in the heart of Harvard Square, the epicenter of Cambridge, Massachusetts. Future tenants are invited to discover the tremendous redevelopment potential of this iconic property through a blend of historic preservation with modern amenities. World-class academic institutions, top tech and life science companies, vibrant neighborhoods, and rich cultural diversity surround this dynamic property. Completely renovated from the inside out, suites on the second and fourth floors are immediately available for lease. The building's diverse tenant mix includes creative and professional businesses and national tenants, such as Starbucks, Cava, and F45 Training. Occupancy terms are negotiable, with lease rates available upon request. Building tenants enjoy state-of-the-art HVAC, private outdoor space, operable windows, and more. Historical and cultural offerings, cobblestone streets, and a unique blend of over 350 dining, retail, and entertainment options within a quarter-mile encompass The Abbot. This section of Cambridge is one of the most iconic locations in the market and one of the most accessible. Situated directly across the street from Harvard Square Red Line Station, the third-most active station in the area, tenants have access to over 23,000 daily riders. The Abbot boasts unparalleled traffic and amenities, making it a draw for customers, businesses, and retailers alike.

Date on Market:

2026-03-10

Worcester Office for Lease - Worcester Metro

Situated on the bustling UMass Chan Medical School Campus, 403 Belmont Street is a state-of-the art medical facility boasting approximately 108,750 +/- SF of rentable area on 4 floors. The building includes an attached garage with a covered walkway connected to the 3rd floor, allowing for seamless patient and employee access. Ratio for parking is 4 / 1,000 SF. Tenants of 403 Belmont Street have access to the cafe and fitness center, located at the Albert Sherman Center. The Veteran Affairs (VA) outpatient clinic of Worcester occupies more than 50,000 SF within the Class A medical office building. The outpatient clinic offers primary care and specialty health services including laboratory services, physical therapy, nutrition counseling, radiology, and more. At 403 Belmont Street, 38,646 +/- SF remain available for lease on two floors, which can be subdivided to accommodate tenants from 5K SF and above. The space is ideal for vibrant medical practices looking to grow and expand.

Date on Market:

2022-10-21