188 Life Science Properties for Lease in Massachusetts, USA

Woburn Flex for Lease - Burlington/Woburn

1,875 SF flex space (~432 SF office, ~1,443 SF warehouse). Please note this is Suite D, 1st floor, Ground-level access. Private tailgate. Warehouse has high ceilings (13.5' clear height). Two (2) private in suite bathrooms. One utility sink. Ample parking. Lease assignment (authorized by Cummings Properties)includes one overnight parking space for registered business vehicle. Lease assignment term through August 2029. Office space has two separate offices with new carpeting and freshly painted in Jan. 2026. Warehouse space will be freshly painted. Bathrooms had new floors installed and freshly painted. Easy access to routes I-93 and I-95(128). Plenty of restaurants and shopping nearby.

Date on Market:

2026-03-12

Worcester Flex for Lease - Worcester Metro

Prime Downtown Worcester Retail/Office Space – 1,900 SF | Move-In Ready Position your business for success in one of Worcester’s most visible and accessible locations. This 1,900 SF space sits in a high-traffic plaza with over 20,000 vehicles passing daily, just minutes from I-290 and I-190. Surrounded by major institutions including UMass Memorial, Saint Vincent’s, WPI, and the Biotech Park, this site offers unmatched proximity to healthcare, education, and innovation hubs. Property Highlights: • ?? Free on-site parking + direct bus stop access • ?? High-speed internet, central A/C, and affordable gas heat • ? Three-phase power, city water/sewer, and illuminated signage • ?? Near O’Connell Park and scenic wetlands • ?? Ideal for medical, wellness, office, or retail use Join a thriving mix of successful businesses in a plaza designed for visibility and convenience. The space is fully built out, move-in ready, and available immediately. ?? Contact Justine Snyder at 508-614-8258 to schedule a private tour and explore how this location can elevate your brand.

Date on Market:

2026-02-18

Westford Office for Lease - Concord/Maynard

314 Littleton Road is a modern, high-performance R&D campus located in the heart of the Westford Technology Park, one of the region’s premier innovation corridors. Designed with advanced infrastructure and corporate-grade amenities, the property spans two interconnected buildings constructed in 2008 and 2013, creating a cohesive environment for research, engineering, and technology-driven operations. The campus features robust electrical capacity, redundant systems, and purpose-built improvements including a data center, fitness facility, cafeteria, freight capabilities, and generous parking, ensuring operational efficiency for a wide range of technical users. Positioned less than two miles from I-495 and minutes from Route 2 and Route 3, the property offers seamless access to Greater Boston and surrounding business hubs. A dense cluster of high-tech neighbors such as Nokia, NetScout Systems, Abbott Medical, Nvidia, and Ribbon Communications enhances the area’s dynamic corporate ecosystem. With thoughtfully designed floor plates, high clear heights, and a blend of office, lab, and R&D adaptability, 314 Littleton Road serves as a turnkey headquarters setting for companies seeking both performance and presence in a strategically connected suburban innovation market.

Date on Market:

2026-02-12

Woburn Office for Lease - Burlington/Woburn

Date on Market:

2025-11-06

Woburn Flex for Lease - Burlington/Woburn

Multi-use facility with leasing opportunities for medical manufacturing, lab, and office space. 34 Commerce Way offers 29,464 square feet of available space with a flexible blend of medical manufacturing, lab, and support space, along with a high-quality office build-out suited for a headquarters or advanced R&D operations. Formerly occupied by Amgen, the property includes significant mechanical, electrical, and plumbing infrastructure, along with a sealed loading area and heavy-power capacity, ideal for tech-driven or production-intensive uses. The office area features a contemporary layout with numerous improvements that are either newly built or minimally used. These include private offices, multiple conference rooms, open workstations, two kitchen and break areas, and eight private restrooms. The building's modern design supports both collaborative and private work environments, with ample natural light, LED lighting, and efficient floor layouts. Direct leasing is available with the owner through Wronka Ltd. Located along highly visible Commerce Way, 34 Commerce Way offers direct highway access between the Interstate 95/Interstate 93 interchange and the Commerce Way exit off Interstate 93. The property is ideally positioned near Boston and Cambridge, with excellent transit connections via the nearby Anderson Regional Transportation Center, offering Logan Express, MBTA bus service, and commuter rail access. A wide variety of restaurants, hotels, medical offices, and health and wellness services are easily accessible from the property, including nearby Woburn Village within walking distance, along with Target Plaza and Cummings Park.

Date on Market:

2025-05-16

Canton Flex, Industrial for Lease - Route 1 South

Beautiful hardwood floors and lots of natural light.

Date on Market:

2025-04-28

Woburn Flex for Lease - Burlington/Woburn

25-K Suite 700: Incubator Lab Space – Ideal for Startup companies seeking a mini full-service lab with essential infrastructure already in place; Perfect for biotech startups, incubator programs, and small R&D teams looking for a turnkey lab solution. Support entrepreneurs, startups, and small business owners as they launch and grow their ventures. Includes: 8' Fume Hood with dedicated make-up air and exhaust; Bio Safety Cabinet; Lab Sink with point-of-use acid neutralization tank; Benchwork for research and development; Eyewash Station for lab safety compliance; Gas Connection for lab operations. Direct Lease including Short-Term sublease.

Date on Market:

2025-03-03

Cambridge Retail for Lease - Mid-Cambridge/Harvard Sq

This fully equipped restaurant and bar includes 40 beer taps, a beer cooler with storage for 40 kegs, high-speed kiddie exhaust system,and a grease trap. A complete list of equipment is available upon request Storage:The facility has a walk-in refrigerator and freezer located in the basement. *Liquor License: Full liquor license issued by the City of Cambridge. Seating Capacity: The establishment can accommodate 99 diners plus bar seating Location: The restaurant is located in the Restaurant Hub of Cambridge, specifically in Inman Square, which is in close proximity to MIT and Harvard University. Nearby Amenities and Restaurants: - Christina’s Homemade Ice Cream - All Star Sandwich Bar - All Star Pizza Bar - Inman Square Wine & Spirits - Casa Portugal Restaurant - Puritan Oyster Bar - Oak Bistro - Christina’s Spice & Specialty Foods - East Cambridge Savings Bank - The Druid - CHA Cambridge Hospital - And many more. **Operational History:** The property has been grandfathered as a restaurant since 1986. Parking: There are 4 on-site parking spaces available, with additional parking options nearby after 5:00 PM. Loading Area: The loading area is located in the parking lot. Traffic Count: Approximately 22,358 vehicles pass through the intersection of Cambridge and Prospect Streets daily. **Utilities: The property has separately metered utilities for electricity, water, and gas. Water & Sewer Services: These services are provided by the City of Cambridge.

Date on Market:

2025-01-24

Peabody Office for Lease - Peabody/Salem

Beautiful Three-story Brick/Stone Mill building with sandblasted Brick and Notched Beam Construction. 5000-9500 Square feet available. 1st Floor, cement floor, with loading dock and direct level access with forklift, Renovated/updated for a modern space. High Ceilings, with 2 ADA bathrooms on each floor, Elevator, Plenty of parking. Currently Available. Outstanding potential, with fantastic and convenience location. Easy access to 128 95, Route 1. Start up or expansion possibilities are endless. Lease terms flexible, Long-term preferred. GB zoned (city approved usage in hand and available by request) Salesroom Showcase, Church/religious facility, Commercial green house, Medical facility, License Day care, School, College, Retail Facility, Personnel Service Establishment, Business support services, Banks/ Financial services, Doctor office, Contractor office, Warehousing, Radio/TV broadcasting ,Printing/Reproduction, Sign shop all allowed, many more by Special permit review only.

Property Type:

Industrial

Date on Market:

2025-06-12

Worcester Office for Lease - Worcester Metro

Situated in the heart of Worcester's Gateway Park, 85 Prescott Street offers an unparalleled setting for businesses seeking to foster innovation, collaboration, and growth. With notable neighbors within walking distance such as WPI (A top STEM university solving real-world problems through hands-on projects and global engagement) and Massachusetts Biotech Initiatives (the longest-running life sciences incubator in the Commonwealth), as well as its proximity to all major highways and retail amenities, 85 Prescott Street is an ideal location for any business looking to grow with the city of Worcester. Join a community-hub, housing tenants such as the Massachusetts Academy of Math and Science at WPI, WPI Robotics Engineering, WPI University Advancement and the Research Solutions Institute, as well as many other medical and professional offices.

Date on Market:

2026-03-27

Ashland Flex for Lease - Hopkinton/Holliston

159 Chestnut Street in Ashland, MA, is a 21,600+/- flex building that boasts an adaptable layout and can accommodate a variety of uses from R&D to light distribution and more. Located in the heart of Ashland, Massachusetts, with convenient access to major routes like the Massachusetts Turnpike (I- 90), Routes 126 and 135, this spot offers excellent connectivity to Boston and nearby MetroWest towns, making it ideal for both local and commuting professionals.

Date on Market:

2024-10-09

Haverhill Office, Flex for Lease - Lawrence/Andover

Located in Haverhill’s Historic Downtown area within walking distance to many restaurants and shops. 143 Essex Street is an eight-story commercial building with dynamic spaces, immediate access to the commuter line Haverhill, North station, and I495. The mixed use spaces are perfect for small businesses or storage needs. Loading dock and freight elevator allow for easy access to spaces. Parking available on site.

Date on Market:

2026-04-13

Natick Office/Medical for Lease - Concord/Maynard

Property Type:

Flex

Date on Market:

2025-09-04

Watertown Office for Lease

One of a kind warehouse/office hybrid space. Newton/Watertown line. Garden level. Needs cosmetics but well worth it at this price. Heat and hot water included. Perfect for light industrial, kinder garden, after school, office, etc. 7 parking can be included in rent. Don't miss this! Right off the mass pike highway. In the zone of major biotech development in Watertown Sq. Hard to find a better location or price in this prime area.

Date on Market:

2023-12-28

Worcester Office/Medical for Lease - Worcester Metro

Kelleher & Sadowsky is pleased to present 7,250 RSF - 33,000 RSF of high-quality office space available immediately for sublease at 306 Belmont Street in Worcester, MA. Formerly occupied by UMass Memorial Health, the space is in excellent condition and features a versatile layout that includes a mix of private offices, open work areas, training and conference rooms, and access to building amenities. Select furnishings may be available as part of the sublease. Ideally situated on Route 9 with quick access to I-290, 306 Belmont Street offers exceptional connectivity to the region’s colleges, hospitals, and surrounding com-munities. The property is located directly across from UMass Memorial’s University Campus, AbbVie’s bio-research facility, and The Reactory — Worcester’s rapidly developing biotech park. Don’t miss the opportunity to establish your presence in the heart of Worcester’s thriving life sciences and bio-tech corridor. Contact us today to schedule a tour.

Property Type:

Office

Date on Market:

2023-09-18

Bedford Office for Lease - Concord/Maynard

Rent is full service gross including utilities, net of interior cleaning. Presently available for lease is 1,545 - 15,000 +/- SF of first and second floor office/flex space. Situated with IND-B zoning, 4 Preston Court is strategically positioned near Hartwell Avenue in Lexington, MA. 4 Preston stands as a recently renovated office/flex building, showcasing ample surface parking at a ratio of 3.64 spaces per 1,000 square feet, equipped with a passenger/freight elevator capable of handling up to 4,500 lbs, and featuring contemporary common areas. Noteworthy neighbors encompass prominent entities such as Thermo Fisher Scientific, Stoke, Diversified Technologies, Cubic PV, and UCB. Within a 3-mile radius of the property, a workforce of 16,053 white-collar professionals thrives, contributing to a rich talent pool while enjoying proximity to some of Boston's most affluent suburbs. Encircled by conservation land, the property lies adjacent to the Minuteman Bike Path and Hanscom Air Force Base, with convenient accessibility to Routes 3, 128, and 225.

Date on Market:

2025-01-09

Cambridge Flex for Lease - E Cambridge/Kendall Sq

In 2021, Ownership completed a new façade on the building with the intention of completing the Lobby Renovation Project in Summer 2022. The Lobby Renovation will include a new at-grade accessible entrance, new freight elevator and stair column with access to the roof and a newly accessible Tenant Opportunity. This is the ideal time to coordinate with our Contractor to deliver your ideal lab space to Kendall Square.

Property Type:

Industrial

Date on Market:

2022-07-18

Marlborough Office, Flex for Lease

313 Boston Post Road is a first class, two-story building located along Route 20 in Marlborough, MA. The 76,322 SF property is perfectly positioned in the MetroWest market between Routes I-495, I-290 and I-90/Mass Pike. Tenants will enjoy convenient access to all area highways and proximity to a wealth of restaurants and retail stores. The building offers flexible floor plates and a state-of-the-art environment for its tenants, complete with a two-story atrium lobby and fitness center.

Date on Market:

2026-04-07

Framingham Office, Industrial for Lease - Framingham/Natick

Strategically situated in Downtown Framingham, The Offices at Dennison Triangle, located at 39 Grant Street, offers completely renovated office space in a vibrant Boston suburb. The recent renovations include all-new building systems and ideal layouts for small lab space and general office users, with suites starting at 500 square feet. Businesses can customize their space to their liking since most buildout costs will be included in the rental rate. Features at 39 Grant Street include underground parking, 13-foot high ceilings with 10-foot mahogany windows for abundant natural light, two passenger elevators, one freight elevator, exposed ceilings, and designs for heavy floor loads. The property is very walkable, surrounded by popular breweries, shops, dining spots, and neighborhood amenities. It is also just a half-mile walk to the Framingham Commuter Rail Station and a short drive to Worcester Road and the Massachusetts Turnpike/I-90. The Logan International Airport is less than 40 minutes away for business travel needs. Given the convenience to transit and major transportation routes, businesses enjoy access to a significant potential workforce.

Date on Market:

2025-12-11

Framingham Office, Flex for Lease - Framingham/Natick

1 Grant Street is a historic building located in the heart of the Framingham neighborhood in Framingham, MA. This property features five floors of office and lab space and totals about 75,000 square feet. This building is conveniently located within a three-minute walk to MBTA Commuter rail to Boston/Worcester. Ample parking in both surface and covered spaces are readily available and the building is located next door to popular establishments including Jacks Abby and Springdale Brewery. The lobby and courtyard have recently gone through renovations providing a high-class tenant experience.

Date on Market:

2025-09-08

Marlborough Office for Lease

Marlboro Executive Park at 65 Boston Post Road W is near Route 20 in Marlborough, Massachusetts. This office building features a ribbon glass exterior and a three-story, rounded glass wall with floor-to-ceiling windows that flood interior stairwells with natural light. The property includes two passenger elevators, 240 surface parking spaces, and 277/480-volt, 1200-amp electricity. Benefit from efficient floorplates allowing suite layout changes to best suit tenant needs. Marlboro Executive Park offers secure keycard access, new bathrooms, and waterless environmental technology. The property is surrounded by abundant amenities with multiple shopping centers within a 10-minute walk, offering shopping, dining, entertainment, and personal services. A small city with plenty to offer, Marlborough is ideally situated along the Massachusetts Innovation Corridor and is considered a premier business destination and a regional biotech hub. The city's progressive management, pro-business administration, and well-maintained infrastructure have attracted some of the region's largest employers, including GE Healthcare, Quest Diagnostics, Raytheon, Hologic, Sunovion Pharmaceuticals, Ken's Foods, and SanDisk. Marlborough is also home to the New England Sports Center and hosts New England's largest Labor Day parade. Employers have direct access to a highly skilled workforce with leading higher education institutions, such as Harvard University and Massachusetts Institute of Technology, only 40 minutes away. Marlboro Executive Park sits a half-mile from the I-495 and Route 20 intersection, allowing immediate access to nearby markets throughout Massachusetts.

Date on Market:

2025-07-08

Waltham Office for Lease

204 2nd Avenue is a multi-tenant office building with wide range of tenants from startups to biotech. The Building is conveniently located in Waltham directly off the Route 95 Exit 27B with freeway visibility and signage opportunities. Opportunity to lease office space within the four story professional building. Sure to meet all your business needs. For additional information contact property owner, Brett Marley.

Date on Market:

2026-03-13

Lowell Office, Flex for Lease - Lowell/Chelmsford

The Offices at Boott Mills is a superbly restored 19th century textile mill with 110,000 square feet of first class office space set on one acre in historic downtown Lowell, MA. Built in 1871 and restored in 1990 for office use, The Offices at Boott Mills encompasses three stories of dramatic post and beam construction, high ceilings, hardwood floors and arched doorways. Enormous windows soak in abundant sunlight. Classic brick and beam finishes evoke Lowell's industrial history. The Offices at Boott Mills is located in Lowell's National Historic Park with direct access to newly renovated luxury apartments and condominiums. A courtyard borders two sides of the building. Inside a modern lobby of stone and brushed chrome finishes welcomes visitors. Flexible floor plans enable easy division and customization of spaces.

Date on Market:

2026-04-24

Pittsfield Office for Lease

First class renovated four story office building located in downtown Pittsfield, MA. Located next to the downtown municipal parking garage, one block from downtown Pittsfield.

Date on Market:

2024-12-17