118 Life Science Properties for Lease in Massachusetts, USA

Cambridge Retail for Lease - Mid-Cambridge/Harvard Sq

This fully equipped restaurant and bar includes 40 beer taps, a beer cooler with storage for 40 kegs, high-speed kiddie exhaust system,and a grease trap. A complete list of equipment is available upon request Storage:The facility has a walk-in refrigerator and freezer located in the basement. *Liquor License: Full liquor license issued by the City of Cambridge. Seating Capacity: The establishment can accommodate 99 diners plus bar seating Location: The restaurant is located in the Restaurant Hub of Cambridge, specifically in Inman Square, which is in close proximity to MIT and Harvard University. Nearby Amenities and Restaurants: - Christina’s Homemade Ice Cream - All Star Sandwich Bar - All Star Pizza Bar - Inman Square Wine & Spirits - Casa Portugal Restaurant - Puritan Oyster Bar - Oak Bistro - Christina’s Spice & Specialty Foods - East Cambridge Savings Bank - The Druid - CHA Cambridge Hospital - And many more. **Operational History:** The property has been grandfathered as a restaurant since 1986. Parking: There are 4 on-site parking spaces available, with additional parking options nearby after 5:00 PM. Loading Area: The loading area is located in the parking lot. Traffic Count: Approximately 22,358 vehicles pass through the intersection of Cambridge and Prospect Streets daily. **Utilities: The property has separately metered utilities for electricity, water, and gas. Water & Sewer Services: These services are provided by the City of Cambridge.

Date on Market:

2025-01-24

Waltham Industrial for Lease

Versatile commercial/industrial space for lease in Waltham. The property contains over 14K RSF on two levels, which is currently demised for two tenants or can be combined for a single user. Both levels can accommodate a variety of commercial, industrial, manufacturing and/or warehousing needs. The building contains a double wide exterior loading dock and a small overhead door on the opposite side of the property. The building is fully sprinklered and air conditioned on both levels and offers 15+ parking spaces. Flexible rents and lease terms available. Please see attached flyer for additional information!

Date on Market:

2024-12-13

Worcester Office for Lease - Worcester Metro

Situated in the heart of Worcester's Gateway Park, 85 Prescott Street offers an unparalleled setting for businesses seeking to foster innovation, collaboration, and growth. With notable neighbors within walking distance such as WPI (A top STEM university solving real-world problems through hands-on projects and global engagement) and Massachusetts Biotech Initiatives (the longest-running life sciences incubator in the Commonwealth), as well as its proximity to all major highways and retail amenities, 85 Prescott Street is an ideal location for any business looking to grow with the city of Worcester. Join a community-hub, housing tenants such as the Massachusetts Academy of Math and Science at WPI, WPI Robotics Engineering, WPI University Advancement and the Research Solutions Institute, as well as many other medical and professional offices.

Date on Market:

2026-03-27

Watertown Office for Lease

One of a kind warehouse/office hybrid space. Newton/Watertown line. Garden level. Needs cosmetics but well worth it at this price. Heat and hot water included. Perfect for light industrial, kinder garden, after school, office, etc. 7 parking can be included in rent. Don't miss this! Right off the mass pike highway. In the zone of major biotech development in Watertown Sq. Hard to find a better location or price in this prime area.

Date on Market:

2023-12-28

Worcester Office/Medical for Lease - Worcester Metro

Kelleher & Sadowsky is pleased to present 7,250 RSF - 33,000 RSF of high-quality office space available immediately for sublease at 306 Belmont Street in Worcester, MA. Formerly occupied by UMass Memorial Health, the space is in excellent condition and features a versatile layout that includes a mix of private offices, open work areas, training and conference rooms, and access to building amenities. Select furnishings may be available as part of the sublease. Ideally situated on Route 9 with quick access to I-290, 306 Belmont Street offers exceptional connectivity to the region’s colleges, hospitals, and surrounding com-munities. The property is located directly across from UMass Memorial’s University Campus, AbbVie’s bio-research facility, and The Reactory — Worcester’s rapidly developing biotech park. Don’t miss the opportunity to establish your presence in the heart of Worcester’s thriving life sciences and bio-tech corridor. Contact us today to schedule a tour.

Property Type:

Office

Date on Market:

2023-09-18

Bedford Office for Lease - Concord/Maynard

4 Preston Court presents a rare opportunity to secure up to 15,000 SF of contiguous first and second-floor space in the heart of Greater Boston’s premier R&D and life sciences corridor. Situated in Bedford’s accommodating IND-B zoning district, this space is engineered for laboratory users, light manufacturing, tech R&D, or a corporate headquarters. The building’s infrastructure is built to perform, featuring a heavy-duty 4,500 lb. capacity passenger/freight elevator and flexible floor plates that can easily integrate dry labs, assembly areas, and collaborative office space. Neighboring industry giants like Thermo Fisher Scientific and Stoke Therapeutics, the property offers unparalleled access to a highly skilled STEM workforce. With a parking ratio of 3.64/1,000 SF and immediate connectivity to Route 3 and I-95/Route 128, 4 Preston Court is the ideal launchpad for growing tech and bioscience firms. Ideal For: Laboratory Users · Light Manufacturing · R&D Facilities · Corporate Headquarters · Technology Firms

Date on Market:

2025-01-09

Cambridge Flex for Lease - E Cambridge/Kendall Sq

In 2021, Ownership completed a new façade on the building with the intention of completing the Lobby Renovation Project in Summer 2022. The Lobby Renovation will include a new at-grade accessible entrance, new freight elevator and stair column with access to the roof and a newly accessible Tenant Opportunity. This is the ideal time to coordinate with our Contractor to deliver your ideal lab space to Kendall Square.

Property Type:

Industrial

Date on Market:

2022-07-18

Framingham Office, Industrial for Lease - Framingham/Natick

Strategically situated in Downtown Framingham, The Offices at Dennison Triangle, located at 39 Grant Street, offers completely renovated office space in a vibrant Boston suburb. The recent renovations include all-new building systems and ideal layouts for small lab space and general office users, with suites starting at 500 square feet. Businesses can customize their space to their liking since most buildout costs will be included in the rental rate. Features at 39 Grant Street include underground parking, 13-foot high ceilings with 10-foot mahogany windows for abundant natural light, two passenger elevators, one freight elevator, exposed ceilings, and designs for heavy floor loads. The property is very walkable, surrounded by popular breweries, shops, dining spots, and neighborhood amenities. It is also just a half-mile walk to the Framingham Commuter Rail Station and a short drive to Worcester Road and the Massachusetts Turnpike/I-90. The Logan International Airport is less than 40 minutes away for business travel needs. Given the convenience to transit and major transportation routes, businesses enjoy access to a significant potential workforce.

Date on Market:

2026-06-25

Bedford Office for Lease - Lowell/Chelmsford

19 & 23 Crosby are multi-tenant buildings with a wide mix of tenants including accounting and financial firms, technology startups, R&D and lab and an on-site day care facility. Spaces have great window lines, lots of natural light and abundant parking. Spaces can be built to suit as needed. 19 & 23 Crosby are conveniently located directly off Route 3 Exit 26 less than 2 miles north of Route 95. Opportunity to lease space within one of two buildings. Sure to meet all your business needs. For additional information contact property owner, Brett Marley.

Date on Market:

2026-07-27

Framingham Office for Lease - Framingham/Natick

1 Grant Street is a historic building located in the heart of the Framingham neighborhood in Framingham, MA. This property features five floors of office and lab space and totals about 75,000 square feet. This building is conveniently located within a three-minute walk to MBTA Commuter rail to Boston/Worcester. Ample parking in both surface and covered spaces are readily available and the building is located next door to popular establishments including Jacks Abby and Springdale Brewery. The lobby and courtyard have recently gone through renovations providing a high-class tenant experience.

Date on Market:

2026-06-10

Marlborough Office for Lease

Marlboro Executive Park at 65 Boston Post Road W is near Route 20 in Marlborough, Massachusetts. This office building features a ribbon glass exterior and a three-story, rounded glass wall with floor-to-ceiling windows that flood interior stairwells with natural light. The property includes two passenger elevators, 240 surface parking spaces, and 277/480-volt, 1200-amp electricity. Benefit from efficient floorplates allowing suite layout changes to best suit tenant needs. Marlboro Executive Park offers secure keycard access, new bathrooms, and waterless environmental technology. The property is surrounded by abundant amenities with multiple shopping centers within a 10-minute walk, offering shopping, dining, entertainment, and personal services. A small city with plenty to offer, Marlborough is ideally situated along the Massachusetts Innovation Corridor and is considered a premier business destination and a regional biotech hub. The city's progressive management, pro-business administration, and well-maintained infrastructure have attracted some of the region's largest employers, including GE Healthcare, Quest Diagnostics, Raytheon, Hologic, Sunovion Pharmaceuticals, Ken's Foods, and SanDisk. Marlborough is also home to the New England Sports Center and hosts New England's largest Labor Day parade. Employers have direct access to a highly skilled workforce with leading higher education institutions, such as Harvard University and Massachusetts Institute of Technology, only 40 minutes away. Marlboro Executive Park sits a half-mile from the I-495 and Route 20 intersection, allowing immediate access to nearby markets throughout Massachusetts.

Date on Market:

2025-02-13

Chelmsford Office/Medical for Lease - Lowell/Chelmsford

This is an Office/R&D/Medical building offering: Power- 3PH, 1200 AMPs, 208V/108V, ceiling height- office: 8'11 inch, R&D: 12', windows- tinted with vertical blinds throughout, HVAC- 17 individual electric a/c units. 5 single zone gas fired roof heating units.First Floor: 26 offices, 2 conference rooms, a cafeteria area, and lobby. Second Floor: R&D finish, 2,500 SF raised computer floor and open space throughout the remaining space built-out with finished ceiling only. Meticulous landscaping. Property is located at the exit ramp from RT 129 onto RT 3 S. Only 1 mile from the RT 3/ RT 495 interchange.

Property Type:

Office

Date on Market:

2025-02-06

Pittsfield Office for Lease

First class renovated four story office building located in downtown Pittsfield, MA. Located next to the downtown municipal parking garage, one block from downtown Pittsfield.

Date on Market:

2024-12-17

Danvers Office, Industrial for Lease - Danvers/Beverly

Well located building in the Danvers Industrial Park off Route 1 -- just south of Route 62. Modern block and brick building located on a well-landscaped lot. Available space has great window line with numerous perimeter offices. Zoning: Industrial II Danvers, MA.

Date on Market:

2026-05-05

Boston Retail for Lease - Seaport

331-339 Northern Avenue is part of Innovation Square Phase III, a newly developed mixed-use project in Boston's Seaport District. The property offers retail leasing opportunities within a Class A environment designed to serve one of the region's most active employment and innovation hubs. Situated along Northern Avenue near Drydock Avenue, the location benefits from proximity to the Raymond L. Flynn Marine Park, major life science employers, waterfront destinations, and the broader Seaport business district. The development incorporates modern building design and a pedestrian-oriented setting that supports retail visibility and customer engagement. On-site amenities include a café, fitness center, conference and event facilities, outdoor seating areas, and a roof deck, creating a dynamic environment for employees, visitors, and customers. The surrounding neighborhood continues to attract leading life science, technology, and professional services organizations, generating a substantial daytime population and ongoing demand for neighborhood-serving retail concepts. The property also benefits from convenient access to Interstate 90, South Station, Logan International Airport, and the Port of Boston. Exceptional public transit connectivity and a highly walkable waterfront setting further enhance accessibility for customers and employees. The combination of new construction, modern amenities, and a location within one of Boston's most established innovation districts positions the property to accommodate a variety of retail and service-oriented users seeking visibility within the Seaport market.

Property Type:

Office

Date on Market:

2026-07-16

Boston Office for Lease - Longwood/Fenway

Located in the heart of Boston's iconic Fenway neighborhood, 98 Brookline Avenue offers an exceptional address at the intersection of business, innovation, and entertainment. Steps from Fenway Park, the property is surrounded by a vibrant mix of restaurants, cafés, hotels, fitness centers, and retail amenities. The location also provides convenient access to the MBTA Green Line, commuter rail, major highways, and Boston's renowned Longwood Medical Area, making it an ideal destination for employees, clients, and visitors alike.

Date on Market:

2026-07-13

Littleton Industrial for Lease - Concord/Maynard

The property at 225 Taylor Street in Littleton, Massachusetts, consists of a planned development on approximately 56 acres of land, zoned IA. The site is designed for GMP manufacturing or warehouse distribution use and includes provisions for two large facilities. Key site services include town water and electricity, gas provided by KeySpan Energy, and a private sewer treatment facility. The location provides immediate access to major roadways including Route 2 and Interstate 495, with close proximity to Route 128 and Interstate 90 (Mass Pike). The property is located approximately 30 miles from Boston and is less than half a mile from an MBTA commuter rail station.

Date on Market:

2026-04-17

North Attleboro Industrial for Lease - Attleboro/New Bedford

215 Plain Street is an industrial property in North Attleboro, Massachusetts, within Bristol County and the Boston I-95 South market. Built in 2006, the one-story facility spans approximately 48,000 square feet on an eight-acre lot. Zoning is recorded as I60. The property is located near Interstate 95, which provides direct connections to Greater Boston and Providence. Surrounding land use includes mixed industrial and commercial sites, contributing to a well-developed logistics corridor serving southeastern Massachusetts and northern Rhode Island.

Date on Market:

2026-06-15

Framingham Office for Lease - Framingham/Natick

Date on Market:

2026-05-13

Braintree Flex for Lease - Quincy/Braintree

Strategically located just minutes from I-93, this versatile commercial property offers a rare combination of existing clinical/office buildout with the infrastructure and flexibility to support a wide range of industrial applications. Originally rooted in industrial use, the building is well-positioned for manufacturing, flex, logistics, and food processing operations. The property features robust 3-phase, 1,200 AMP power, making it ideal for power-intensive users. An efficient site layout with separate ingress and egress allows for seamless truck circulation and easy maneuverability—an increasingly valuable asset for distribution and operational efficiency. Surrounded by a strong mix of neighboring uses including home improvement retailers, hospitality, medical, biotech manufacturing, and Integra LifeSciences, the location benefits from a dynamic and growing commercial ecosystem. Zoned Commercial and situated in a pro-business community, 135 Wood Road presents a compelling opportunity for a variety of users seeking flexibility, accessibility, and long-term growth potential.

Date on Market:

2026-04-25

Dedham Industrial for Lease - Route 1 South

105 Commerce Way has one loading Dock.

Date on Market:

2026-04-20

Weymouth Medical for Lease - Route 3 Corridor

571 Main Street presents an excellent opportunity for a medical practice to lease turn-key space with excellent proximity to South Shore Hospital. The first floor suite is currently laid out with an ample reception/waiting area, a billing office, doctor's office, 6 exam rooms, a lab space, a blood draw room, kitchen/break area, and 3 private bathrooms.

Property Type:

Office

Date on Market:

2026-04-15

Waltham Office for Lease

The Property has exceptional physical characteristics that are uniquely suited for life science. The building is situated in a transformed location with a wealth of amenities including the adjacent hotel, and numerous restaurants and entertainment venues. With an impressive tenant base and bordered by the world’s leading lab companies, the Property is in a unique position to capture the strong life science demand in Greater Boston. LAB & SUITE DETAILS: • Histology Lab with 6' chemical fume hood (CFH) • Tissue Culture (TC) Lab • Engineering Lab with dual anteroom access • Two (2) Laser Labs • Four (4) private offices plus CEO suite • Open office area, shared office, and huddle room • Conference room, reception, and break room with pantry • Dedicated server room • Shipping/receiving with freight elevator access

Date on Market:

2026-03-25

Cambridge Office for Lease - Mid-Cambridge/Harvard Sq

This office property is situated on Cambridge Street in the Wellington-Harrington neighborhood, offering a high-visibility address in the heart of Cambridge. The available suite features a functional layout with three private offices, a reception area, a kitchenette, and a private restroom, designed to complement professional and creative work environments. Natural light enhances the space, while the secured building ensures privacy and reliability for occupants. The location provides seamless accessibility via public transportation and is exceptionally walkable, with bike-friendly routes nearby. Tenants benefit from proximity to leading universities, medical facilities, and biotech firms that define Cambridge’s dynamic business ecosystem. Positioned within a well-connected district, the property serves as a strategic hub for companies seeking connectivity to Kendall Square, downtown Boston, and the broader Greater Boston market.

Date on Market:

2026-03-09