189 Life Science Properties for Lease in Massachusetts, USA

Boston Office for Lease - Seaport

The IDB is home to makers, designers, architects, communicators, researchers, manufacturers, technologists, innovators and entrepreneurs. The complex’s impressive size allows businesses to grow in place and its interconnected nature fosters an open exchange of information and ideas, creating a uniquely collaborative atmosphere that is highly sought after by its entrepreneurial tenant community

Date on Market:

2024-12-18

Boston Office for Lease - Seaport

10 World Trade is a 555,250 SF, 17-story premier life science and office development in Boston's thriving Seaport District. 10 World Trade will empower, connect, and inspire those who are shaping the future by leading the way in health, wellness, and environmentally sustainable, human-centered design. The development is fully-amenitized with a dramatic 45-foot tall atrium, a 150-seat auditorium built for the exchange of ideas, an indoor/outdoor oasis with operable glass walls, a cultural center with rotating exhibits and activations, and a skyline health club with a 300-meter track and a full suite of fitness offerings. From the eco-friendly redesign of World Trade Center Avenue to smart, energy-saving building features, 10 World Trade is unparalleled in its dedication to sustainability and wellness in a future-proof setting. Certifications include LEED Gold, WELL Gold, SITES Gold, WiredScore Platinum, and SmartScore Certified. 10 World Trade also offers 250 parking spaces at the South Boston Waterfront Transportation Center.

Date on Market:

2024-11-22

Charlestown Office for Lease - Charlestown/East Boston

Date on Market:

2026-05-05

Chelmsford Flex for Lease - Lowell/Chelmsford

Date on Market:

2025-07-30

Cambridge Office, Retail for Lease - Mid-Cambridge/Harvard Sq

The Abbot at 18-24 Brattle Street presents a once-in-a-generation opportunity to occupy the most iconic building in the heart of Harvard Square, the epicenter of Cambridge, Massachusetts. Future tenants are invited to discover the tremendous redevelopment potential of this iconic property through a blend of historic preservation with modern amenities. World-class academic institutions, top tech and life science companies, vibrant neighborhoods, and rich cultural diversity surround this dynamic property. Completely renovated from the inside out, suites on the second and fourth floors are immediately available for lease. The building's diverse tenant mix includes creative and professional businesses and national tenants, such as Starbucks, Cava, and F45 Training. Occupancy terms are negotiable, with lease rates available upon request. Building tenants enjoy state-of-the-art HVAC, private outdoor space, operable windows, and more. Historical and cultural offerings, cobblestone streets, and a unique blend of over 350 dining, retail, and entertainment options within a quarter-mile encompass The Abbot. This section of Cambridge is one of the most iconic locations in the market and one of the most accessible. Situated directly across the street from Harvard Square Red Line Station, the third-most active station in the area, tenants have access to over 23,000 daily riders. The Abbot boasts unparalleled traffic and amenities, making it a draw for customers, businesses, and retailers alike.

Date on Market:

2026-03-10

Worcester Office for Lease - Worcester Metro

Situated on the bustling UMass Chan Medical School Campus, 403 Belmont Street is a state-of-the art medical facility boasting approximately 108,750 +/- SF of rentable area on 4 floors. The building includes an attached garage with a covered walkway connected to the 3rd floor, allowing for seamless patient and employee access. Ratio for parking is 4 / 1,000 SF. Tenants of 403 Belmont Street have access to the cafe and fitness center, located at the Albert Sherman Center. The Veteran Affairs (VA) outpatient clinic of Worcester occupies more than 50,000 SF within the Class A medical office building. The outpatient clinic offers primary care and specialty health services including laboratory services, physical therapy, nutrition counseling, radiology, and more. At 403 Belmont Street, 38,646 +/- SF remain available for lease on two floors, which can be subdivided to accommodate tenants from 5K SF and above. The space is ideal for vibrant medical practices looking to grow and expand.

Date on Market:

2022-10-21

Boston Industrial for Lease - Seaport

310-312 North Avenue is a class B industrial building that offers refrigerated industrial condominiums in Boston, MA. The 48,882 square foot building has 26,000 square feet, split between 2 condos, available for sale or lease. The building is conveniently located near two bus lines and eight-minutes away from the Boston Logan International Airport, providing easy access for commuting. Additional to the commuter options, the building Is also within a one to eight-minute drive to eight hotels in the area. Tenants can enjoy industrial spaces with cross docks, refrigeration, and redevelopment opportunities. Employees will find themselves within driving distance of restaurants and banks.

Date on Market:

2024-06-20

Newton Office for Lease - Newton/Brookline

KS Labs @Newton Highlands, located at 19-31 Needham Street, offers completely move-in-ready lab/office flex space in the vibrant Boston suburb of Newton, Massachusetts. Constructed in 1965 and renovated in 2023, the two-story building contains flex space ideally suited for laboratory, biomanufacturing, office, and R&D use. Property features include 3-inch concrete slab floors, loading-dock access, city water and sewer, sprinklers, and backup generators in case of emergencies. The newly built lab space is immediately available for lease. Capitalize on 6-foot fume hoods, brand-new 2-inch water lines, and dedicated 800-amp/480-volt disconnect service. Casework, benching, and chip tanks for acid neutralization are also included. Businesses at KS Labs @Newton Highlands enjoy access to a significant potential workforce with strategic placement near easy Interstate 93 and Route 9 connectivity. For business travel needs, the Logan International Airport is less than a 25-minute drive away. The property is located along a vibrant commercial corridor in a highly walkable area, surrounded by a diverse mix of retail stores, restaurants, and service amenities, such as Bloomingdale's, Shake Shack, Dave's Hot Chicken, The Cheesecake Factory, and Pressed Café.

Date on Market:

2022-05-20

Cambridge Office for Lease - E Cambridge/Kendall Sq

Date on Market:

2025-07-15

Walpole Multiple Space Uses for Lease - I-95 Corridor South

Mixed-use campus ideal for office, R&D, lab, light industrial, and storage uses. Former mill converted into a modern business park with brick and beam finishes. Plentiful on-site parking available. Conveniently located within walking distance of the amenities in Downtown Walpole/MBTA Station. Flexible floor plates. Ample power for flex/light manufacturing users. Loading docks and freight elevator

Date on Market:

2024-12-04

Worcester Flex for Lease - Worcester Metro

20 Reactory Drive and 30 Reactory Drive are adjacent lots with permits in place. By combining these two parcels, The Reactory can accommodate from 95,000 to 380,000 square feet with parking on the combined lots. This allows for companies to design and construct a facility that meets their needs today and expansion for future growth. 31 Reactory Drive is the largest parcel on the campus. With over 24 acres of land, this site can accommodate a large-scale operation in one or multiple buildings. This is an ideal site for those companies that need significant size to start but even more for their growth in the future. With endless flexibility, The Reactory offers companies the ability to scale its operations as their business evolves. • 46 acre life sciences campus • 3 land parcels that can be subdivided or combined • Site can accomodate 70,000 square feet to over 1,000,000 square feet • Permits in hand • Foundation in place at 20 Reactory Drive • 100% support from The Commonwealth of Massachusetts and the City of Worcester • A proven location for Life Sciences Grow with us. Let The Reactory in Worcester be your next move.

Date on Market:

2024-02-29

Medford Office/Medical for Lease - Medford/Malden

One Cabot Road is a four story, ±316,233 SF class A office building located in the thriving community of Medford, Massachusetts. The property recently underwent a $16.9 million amenity upgrade and now features a new lobby lounge, coffee lounge, new fitness center and locker rooms, expansive outdoor patio and a full-service cafe.

Property Type:

Office

Date on Market:

2024-02-23

Cambridge Retail for Lease - Mid-Cambridge/Harvard Sq

The Abbot is the epicenter of Harvard Square. This iconic redevelopment is an irreplaceable world class retail and office destination in the heart of Harvard Square.

Property Type:

Office

Date on Market:

2026-03-17

Cambridge Office, Flex for Lease - Mid-Cambridge/Harvard Sq

Date on Market:

2025-09-29

Beverly Office for Lease - Danvers/Beverly

Build-to-suit office suite with extensive window line overlooking wooded campus. Private shared community break area and restrooms.

Date on Market:

2025-04-07

Milford Retail for Lease - Outlying Worcester

Granite Hill Marketplace is an ideally positioned retail center with flex/warehouse potential in Milford, Massachusetts. Situated on 16.4 acres off Fortune Boulevard, the development totals 97,095 square feet across an upper lot big-box retail building with a big-box retail building and restaurant on the lower portion of the parcel. Space is available immediately for occupancy, with property features that include ample surface parking, over 22-foot ceiling clear heights, full air conditioning, tailboard loading docks, exceptional Interstate 495 visibility, and more. The center is situated within the Highway Industrial (IB) District of Milford and allows for a variety of uses. Benefit from incredible building adaptability for retail, office, manufacturing, production, life science research and development, bio-manufacturing/cGMP, data center, medical and many other uses. Plus, Granite Hill Marketplace is directly adjacent to major anchors such as Target and Lowe’s. Granite Hill Marketplace sits 30.3 miles southwest of Downtown Boston and 32.7 miles north of Providence, Rhode Island. Experience seamless connectivity to major highway systems and population centers with strategic access to Interstate 495 in a half mile and reach Route 9, Interstate 90, and Interstate 95 within minutes. A growing population of nearly 137,000 residents lives within a 15-minute drive from the property, representing an average household income exceeding $150,000 annually in addition to the yearly consumer spending of $4.5 billion dollars. Annual consumer spending within a mile is averaged at $16.1 million dollars.

Date on Market:

2025-04-28

Chelsea Office for Lease - Chelsea/Revere

Tons of area amenities within walking distance from the property. Highly attentive property management. Cost effective office space that Landlord is willing to build out for potential tenants to their required specs. Immediately accessible to the commuter train station, just one stop to North Station. Bus service to Wellington (orange), Haymarket (green) and Wonderland (blue) immediately accessible. Boston Logan International Airport just minutes away. Easy on/off Routes 1, 93 and 16.

Date on Market:

2025-09-02

Woburn Office, Flex for Lease - Burlington/Woburn

130 New Boston Street in Woburn, Massachusetts, is a 56,286-square-foot, three-story office/lab building located approximately 10 miles north of Boston. The spaces for lease come with incredible built-in lab features, including 2-inch, medium-pressure lines for gas, lab wastewater with chip tanks under each lab sink, backup power with a 50 kW generator, strong electricity at 20 watts/SFEACH, HVAC, and flume hoods. Additionally, the building comes equipped with conveniences for employees, including an on-site café that provides breakfast, lunch, and catering services. KS Labs @ Woburn Village is situated in a commuter’s paradise, with several dining options and neighborhood conveniences. Tenants enjoy multiple transit options, including Interstates 93 and 95 and the MBTA’s Commuter Rail at Anderson/Woburn and Mishwam Station within walking distance. Woburn Village, less than 1 mile from the property, is a curated mix of nationally recognized retailers and restaurants, including Shake Shack, CAVA, Panera Bread, Crumbl Cookies, DSW, T.J. Maxx, HomeGoods, and Chase Bank. Woburn serves as a hub of innovation in Boston’s lab office ecosystem. Noteworthy tenants in the Woburn Lab Cluster include Azurity Pharmaceuticals Inc., Covaris, Spear Bio, Abpro, Angene, and more. Woburn also benefits from proximity to other clusters, including Burlington/Bedford Lab, Hartwell Avenue, Waltham Lab Cluster, and Hayden Avenue. There is infinite potential for synergy between these major clusters and tenants across the greater Boston area.

Date on Market:

2026-05-21

Framingham Flex for Lease - Framingham/Natick

On behalf of our client, CBRE is pleased to present an exciting opportunity at 111 Lawrence Street in Framingham, Massachusetts. Recently renovated in 2008, the building offers ±84,420 SF of Class A office space. 111 Lawrence Street is conveniently located minutes off Route 9, provides immediate access to the Massachusetts Turnpike (I-90) and is a 30-minute drive from downtown Boston and Logan International Airport. Located in the heart of MetroWest, Framingham has superior identity and outstanding design for companies seeking a corporate location in a first class office building with unparalleled on/off access to the Mass Pike. Area amenities include many restaurants, fast food and retail options, including Shoppers World, Natick Mall and an upscale Life Time Fitness facility. Local hotels include Crowne Plaza, Hampton Inn, and Courtyard Marriott.

Date on Market:

2022-10-24

Peabody Flex for Lease - Peabody/Salem

Property Type:

Office

Date on Market:

2022-02-02

Burlington Office for Lease - Burlington/Woburn

Date on Market:

2023-02-09

Boston Office for Lease - Seaport

Seaport Circle is a mixed-use development featuring 650,000 square feet of life science research and office space in Boston's most prominent life science cluster. The project is pursuing LEED Platinum designation, with a 90% reduction in natural gas use. The two-tower design will provide flexible floor plates ranging from 25,000-75,000 square feet. In addition to state-of-the-art Class A lab and office space, the building will include best-in-class tenant amenity spaces and approximately 5,000 square feet of retail space. Seaport Circle will also include a 15,000 SF stand-alone South Boston Waterfront Job Training Pavilion (the Pavilion) with an ambitious mission focused on training for skilled jobs in life sciences and adding talent to the pipeline of opportunity in the Boston area’s exploding life science sector.

Date on Market:

2023-02-06

Wilmington Office, Flex for Lease - Wilmington/Reading

93 Labs is a first-class suburban office, R&D, and lab building delivering 150,000 RSF of life science space. The property is positioned directly off Interstate 93, minutes from Interstate 495, and less than 18 miles North of Cambridge. All located within one of Greater Boston’s prominent suburban life science clusters. Amenities on site and within walking distance.

Date on Market:

2025-12-16

Hopkinton Office for Lease - Hopkinton/Holliston

35 Parkwood Drive, located within the Hopkinton Corporate Center in Hopkinton, Massachusetts, presents an exceptional opportunity to lease Class A office space. Formerly the EMC World Headquarters, the best-in-class two-story multi-tenant building underwent a comprehensive renovation in 2018 and now features a modern main lobby, large conference rooms, outdoor patio space, updated common areas, four passenger elevators, a fitness center with showers, and on-site service kiosks. Available suites range from approximately 4,155 to 12,150 square feet on the first and second floors, with flexible configurations and negotiable lease terms to suit various professional office and R&D users. Month-to-month coworking opportunities are also available through Regus. Tenants benefit from heavy power infrastructure, telecom/data wiring throughout the building, and abundant parking. Just a half-mile off Interstate 495 at Exit 54, one exit south of the Mass Pike, 35 Parkwood Drive offers excellent regional access about 40 minutes southwest of Boston. Nearby amenities include Starbucks, Dunkin', 110 Grill, Cumberland Farms, and The Spoon café. Owned and managed by the same experienced team, the property delivers reliability, responsiveness, and a high-quality work environment.

Date on Market:

2026-02-12