118 Life Science Properties for Lease in Massachusetts, USA

Newton Office, Retail for Lease - Newton/Brookline

Multiple spaces for lease ranging from 1,456 - 3,717 SF and 1,256 - 2,138 SF • Ground floor of a 173,000 SF office building leased to various institutional companies such as Clearview Healthcare Partners and Odysseys Unlimited. • Existing (shared) parking deck containing 344 spaces in addition to ample street parking and an abutting 67 space public parking lot • Ground-Level co-tenants include Pediatrics of Newton Wellesley, Corepower Yoga, Sola Salon and Thai Amarin • Located directly at the heavily trafficked confluence of the Massachusetts Turnpike, Washington Street and Centre Street • Positioned in the Newton Corner village of Newton, and directly engrained in the interior residential road network in addition to its ideal ingress/egress from various access points

Date on Market:

2026-06-03

Worcester Flex for Lease - Worcester Metro

Prime Downtown Worcester Retail/Office Space – 1,900 SF | Move-In Ready Position your business for success in one of Worcester’s most visible and accessible locations. This 1,900 SF space sits in a high-traffic plaza with over 20,000 vehicles passing daily, just minutes from I-290 and I-190. Surrounded by major institutions including UMass Memorial, Saint Vincent’s, WPI, and the Biotech Park, this site offers unmatched proximity to healthcare, education, and innovation hubs. Property Highlights: *****16,000 Traffic count daily!****** • Free on-site parking + direct bus stop access • ?? High-speed internet, central A/C, and affordable gas heat • ? Three-phase power, city water/sewer, and illuminated signage • ?? Near O’Connell Park and scenic wetlands • ?? Ideal for medical, wellness, office, or retail use Join a thriving mix of successful businesses in a plaza designed for visibility and convenience. The space is fully built out, move-in ready, and available immediately. ?? Contact Justine Snyder at 508-614-8258 to schedule a private tour and explore how this location can elevate your brand.

Date on Market:

2026-02-18

Newton Office for Lease - Newton/Brookline

Located in the heart of Newton Corner, 275 Washington Street—commonly known as One Newton Place—is a prominent Class B, four-story office and retail building totaling approximately 173,000 square feet. Originally built in 1985 and renovated in 2005, the property offers a flexible mix of office and ground-floor retail space suited for professional, medical, and service-oriented tenants. The building features efficient floor plates, approximately 12-foot unfinished ceiling heights, and a strong on-site and nearby amenity base. Strategically positioned at the highly trafficked confluence of Washington Street, Centre Street, and the Massachusetts Turnpike (I-90), the property provides exceptional regional accessibility, including express bus service to Boston and convenient highway access. Tenancy includes a mix of established corporate, healthcare, and lifestyle users, contributing to a vibrant, walkable environment within one of Newton’s most connected commercial villages.

Date on Market:

2026-07-18

Andover Flex for Lease - Lawrence/Andover

Date on Market:

2026-01-13

Stoughton Office for Lease - Route 24

100 Technology Center Drive is a well-located commercial property within a established suburban office and technology park in Stoughton, Massachusetts. The building offers a professional corporate environment with convenient access to major regional highways, supporting efficient connectivity to Greater Boston and surrounding markets. Designed to accommodate a range of office, R&D, or light industrial uses, the property benefits from ample on-site parking, landscaped surroundings, and proximity to local amenities, making it an attractive option for technology-focused and professional tenants.

Date on Market:

2026-01-06

Malden Office for Lease - Medford/Malden

11 Dartmouth Street is a newly constructed 188,000 square foot Class A multi use building designed to accommodate office medical research and development and life science tenants. The property offers highly flexible floor plates up to 20,000 square feet and features a best in class amenity package including indoor and outdoor common areas an onsite fitness center tenant event spaces 138 parking spaces and 80 bike storage spaces. The building is designed for wellness and efficiency with abundant natural light panoramic views and convenient access to the Malden Center MBTA Station. With modern infrastructure multiple passenger and freight elevators and lab ready building systems 11 Dartmouth Street provides a future focused environment ideal for innovative organizations.

Date on Market:

2025-11-17

Boston Office for Lease - Seaport

Located in Boston’s vibrant Seaport District, 19 Fid Kennedy Avenue is part of The Foundry at Drydock, a premier Class A office building offering approximately 250,959 square feet of modern workspace. Built in 2022, this eight-story property features state-of-the-art design, controlled access security, and on-site staff, making it ideal for businesses seeking a dynamic and secure environment. The building includes biotech and lab-ready spaces, waterfront views, and easy access to public transportation, dining, and entertainment options, creating an inspiring setting for innovation and collaboration.

Date on Market:

2025-11-10

Marlborough Retail for Lease

BLACKLINE Retail Group, LLC has been retained by the Owner, on an exclusive basis, to lease 57 Main Street in Marlborough, MA. Prime downtown Marlborough development featuring 92 units, 3,300 SF of retail, and a landscaped courtyard. Just five minutes from I-495, the property enjoys exceptional accessibility and visibility within one of Greater Boston’s largest employment hubs—home to leading technology, life science, and manufacturing companies. Its central location and mixed-use design make it an ideal destination for retailers seeking a vibrant, high-traffic setting in a rapidly growing downtown corridor.

Property Type:

Multifamily

Date on Market:

2025-11-05

Hopkinton Office, Flex for Lease - Hopkinton/Holliston

Date on Market:

2025-10-30

Natick Office for Lease - Framingham/Natick

Date on Market:

2025-10-20

Methuen Industrial for Lease - Lawrence/Andover

Brand-new Class A industrial facility delivering modern specifications in a highly functional, distribution-oriented layout ±147,840 SF total building size, designed to accommodate warehouse, logistics, and light manufacturing users Tilt-up concrete construction with a clean, efficient footprint and scalable interior configuration Currently offering two ±40,000 SF spaces, with the ability to combine for up to ±80,000 SF Strategically positioned in Methuen with strong highway connectivity supporting regional and Greater Boston operations

Date on Market:

2026-01-07

Boston Office, Retail for Lease - Seaport

Positioned in the heart of Boston’s Seaport Innovation District, 7 Channel Center presents a premier opportunity within the established Channel Center Planned Development Area. Surrounded by world-class companies, cultural amenities, and new development, the property is strategically located in one of Boston’s fastest-growing submarkets, driven by strong demand across office, life science, and residential sector

Date on Market:

2025-08-12

Boston Flex for Lease - Seaport

Date on Market:

2025-08-08

Cambridge Office for Lease - E Cambridge/Kendall Sq

Full building lab conversion completed in 2022, offering early stage biotech companies ready to go lab suites.

Date on Market:

2025-08-27

Newton Office for Lease - Newton/Brookline

Date on Market:

2026-03-23

Waltham Flex for Lease

Date on Market:

2025-07-02

Charlestown Flex for Lease - Charlestown/East Boston

Brand New Lab, Heavy R&D, and Clean Room space with ability to modify as needed. Heavy Power, Loading, and other infrastructure available. Perfect space for Light Manufacturing, Electronics, Clean Room, and Advanced Manufacturing Groups.

Date on Market:

2025-05-12

Cambridge Office for Lease - W Cambridge/Alewife

Property Type:

Flex

Date on Market:

2025-05-06

Chicopee Office for Lease - Hampden County

Development Associates is pleased to offer For Lease ± 15,000 SF of Office/Tech/Lab space, available immediately, in Westover Industrial Park in Chicopee, MA.

Property Type:

Specialty

Date on Market:

2025-05-01

Cambridge Office for Lease - E Cambridge/Kendall Sq

Date on Market:

2025-04-02

Worcester Office for Lease - Worcester Metro

One Innovation Drive is a four-story office/laboratory facility with an adjacent single-story parking structure and is known as Building 3 in the UMass Medical & Science Park. Situated alongside the continuously growing UMass Chan Medical School and UMass Memorial Medical Center campus, the UMass Medicine Science Park both contributes to and benefits from the organic synergies created within this interconnected complex. A palpable energy from an unparalleled 10,000+ knowledge seekers on site – in addition to approximately 10 additional neighboring colleges and universities – permeates the campus, encouraging innovative thoughts and collaborative partnerships.

Date on Market:

2026-04-22

Beverly Multiple Space Uses for Lease - Danvers/Beverly

Date on Market:

2026-06-25

Marlborough Office for Lease

KS Labs @293 presents move-in-ready lab and professional office space in the heart of Marlborough, Massachusetts. The office building contains over 200,000 square feet across six floors and is located among numerous MetroWest-based life science companies. Property features include recent renovations and a brand-new amenity center, ensuring a dynamic environment where businesses can innovate and thrive. Enter the building through a sophisticated and natural-light-filled five-story atrium. Tenants have access to a wealth of on-site amenities, such as a full-service café, a conference center, a fitness center with a sauna, daycare services, storage space, and access to rooftop decks. Immediately available lab spec suites offer 39 lab benches, three 6-foot fume hoods with the capacity to add more, a freezer room, dedicated 300-amp/480-volt electric service, and under-sink chip tanks for chemical neutralization. Plus, capitalize on an efficient layout with a reception area, open office space, multiple lab zones, a freezer room, a kitchen/break room, and more. KS Labs @293 is within minutes of the newly opened Apex Center, New England’s largest multi-experience events and entertainment venue. Other surrounding amenities include hotels, retail stores, and restaurants like 110 Grill and Okami. RK Centre, a Hannaford supermarket-anchored regional shopping center, and the 225-unit luxury Talia Apartments are directly adjacent to this best-in-class property. KS Labs @293 is less than a quarter-mile from the recently expanded Route 20, within a mile of Interstate 290, 3 miles to Route 9, and within 4 miles of the Massachusetts Turnpike.

Date on Market:

2026-01-14

Boston Office for Lease - Seaport

10 World Trade is a 555,250 SF, 17-story premier life science and office development in Boston's thriving Seaport District. 10 World Trade will empower, connect, and inspire those who are shaping the future by leading the way in health, wellness, and environmentally sustainable, human-centered design. The development is fully-amenitized with a dramatic 45-foot tall atrium, a 150-seat auditorium built for the exchange of ideas, an indoor/outdoor oasis with operable glass walls, a cultural center with rotating exhibits and activations, and a skyline health club with a 300-meter track and a full suite of fitness offerings. From the eco-friendly redesign of World Trade Center Avenue to smart, energy-saving building features, 10 World Trade is unparalleled in its dedication to sustainability and wellness in a future-proof setting. Certifications include LEED Gold, WELL Gold, SITES Gold, WiredScore Platinum, and SmartScore Certified. 10 World Trade also offers 250 parking spaces at the South Boston Waterfront Transportation Center.

Date on Market:

2024-11-22