189 Life Science Properties for Lease in Massachusetts, USA

Framingham Office for Lease - Framingham/Natick

1 Grant Street is a historic building located in the heart of the Framingham neighborhood in Framingham, MA. This property features five floors of office and lab space and totals about 75,000 square feet. This building is conveniently located within a three-minute walk to MBTA Commuter rail to Boston/Worcester. Ample parking in both surface and covered spaces are readily available and the building is located next door to popular establishments including Jacks Abby and Springdale Brewery. The lobby and courtyard have recently gone through renovations providing a high-class tenant experience.

Date on Market:

2026-06-10

Marlborough Office for Lease

Marlboro Executive Park at 65 Boston Post Road W is near Route 20 in Marlborough, Massachusetts. This office building features a ribbon glass exterior and a three-story, rounded glass wall with floor-to-ceiling windows that flood interior stairwells with natural light. The property includes two passenger elevators, 240 surface parking spaces, and 277/480-volt, 1200-amp electricity. Benefit from efficient floorplates allowing suite layout changes to best suit tenant needs. Marlboro Executive Park offers secure keycard access, new bathrooms, and waterless environmental technology. The property is surrounded by abundant amenities with multiple shopping centers within a 10-minute walk, offering shopping, dining, entertainment, and personal services. A small city with plenty to offer, Marlborough is ideally situated along the Massachusetts Innovation Corridor and is considered a premier business destination and a regional biotech hub. The city's progressive management, pro-business administration, and well-maintained infrastructure have attracted some of the region's largest employers, including GE Healthcare, Quest Diagnostics, Raytheon, Hologic, Sunovion Pharmaceuticals, Ken's Foods, and SanDisk. Marlborough is also home to the New England Sports Center and hosts New England's largest Labor Day parade. Employers have direct access to a highly skilled workforce with leading higher education institutions, such as Harvard University and Massachusetts Institute of Technology, only 40 minutes away. Marlboro Executive Park sits a half-mile from the I-495 and Route 20 intersection, allowing immediate access to nearby markets throughout Massachusetts.

Date on Market:

2025-02-13

Waltham Office for Lease

204 2nd Avenue is a multi-tenant office building with wide range of tenants from startups to biotech. The Building is conveniently located in Waltham directly off the Route 95 Exit 27B with freeway visibility and signage opportunities. Opportunity to lease office space within the four story professional building. Sure to meet all your business needs. For additional information contact property owner, Brett Marley.

Date on Market:

2026-03-13

Chelmsford Office/Medical for Lease - Lowell/Chelmsford

This is an Office/R&D/Medical building offering: Power- 3PH, 1200 AMPs, 208V/108V, ceiling height- office: 8'11 inch, R&D: 12', windows- tinted with vertical blinds throughout, HVAC- 17 individual electric a/c units. 5 single zone gas fired roof heating units.First Floor: 26 offices, 2 conference rooms, a cafeteria area, and lobby. Second Floor: R&D finish, 2,500 SF raised computer floor and open space throughout the remaining space built-out with finished ceiling only. Meticulous landscaping. Property is located at the exit ramp from RT 129 onto RT 3 S. Only 1 mile from the RT 3/ RT 495 interchange.

Property Type:

Office

Date on Market:

2025-02-06

Lowell Office, Flex for Lease - Lowell/Chelmsford

The Offices at Boott Mills is a superbly restored 19th century textile mill with 110,000 square feet of first class office space set on one acre in historic downtown Lowell, MA. Built in 1871 and restored in 1990 for office use, The Offices at Boott Mills encompasses three stories of dramatic post and beam construction, high ceilings, hardwood floors and arched doorways. Enormous windows soak in abundant sunlight. Classic brick and beam finishes evoke Lowell's industrial history. The Offices at Boott Mills is located in Lowell's National Historic Park with direct access to newly renovated luxury apartments and condominiums. A courtyard borders two sides of the building. Inside a modern lobby of stone and brushed chrome finishes welcomes visitors. Flexible floor plans enable easy division and customization of spaces.

Date on Market:

2026-04-24

Pittsfield Office for Lease

First class renovated four story office building located in downtown Pittsfield, MA. Located next to the downtown municipal parking garage, one block from downtown Pittsfield.

Date on Market:

2024-12-17

Danvers Office, Industrial for Lease - Danvers/Beverly

Well located building in the Danvers Industrial Park off Route 1 -- just south of Route 62. Modern block and brick building located on a well-landscaped lot. Available space has great window line with numerous perimeter offices. Zoning: Industrial II Danvers, MA.

Date on Market:

2026-05-05

Framingham Office for Lease - Framingham/Natick

Date on Market:

2026-05-13

Braintree Flex for Lease - Quincy/Braintree

Strategically located just minutes from I-93, this versatile commercial property offers a rare combination of existing clinical/office buildout with the infrastructure and flexibility to support a wide range of industrial applications. Originally rooted in industrial use, the building is well-positioned for manufacturing, flex, logistics, and food processing operations. The property features robust 3-phase, 1,200 AMP power, making it ideal for power-intensive users. An efficient site layout with separate ingress and egress allows for seamless truck circulation and easy maneuverability—an increasingly valuable asset for distribution and operational efficiency. Surrounded by a strong mix of neighboring uses including home improvement retailers, hospitality, medical, biotech manufacturing, and Integra LifeSciences, the location benefits from a dynamic and growing commercial ecosystem. Zoned Commercial and situated in a pro-business community, 135 Wood Road presents a compelling opportunity for a variety of users seeking flexibility, accessibility, and long-term growth potential.

Date on Market:

2026-04-25

Dedham Industrial for Lease - Route 1 South

105 Commerce Way has one loading Dock.

Date on Market:

2026-04-20

Weymouth Medical for Lease - Route 3 Corridor

571 Main Street presents an excellent opportunity for a medical practice to lease turn-key space with excellent proximity to South Shore Hospital. The first floor suite is currently laid out with an ample reception/waiting area, a billing office, doctor's office, 6 exam rooms, a lab space, a blood draw room, kitchen/break area, and 3 private bathrooms.

Property Type:

Office

Date on Market:

2026-04-15

Waltham Office for Lease

The Property has exceptional physical characteristics that are uniquely suited for life science. The building is situated in a transformed location with a wealth of amenities including the adjacent hotel, and numerous restaurants and entertainment venues. With an impressive tenant base and bordered by the world’s leading lab companies, the Property is in a unique position to capture the strong life science demand in Greater Boston. LAB & SUITE DETAILS: • Histology Lab with 6' chemical fume hood (CFH) • Tissue Culture (TC) Lab • Engineering Lab with dual anteroom access • Two (2) Laser Labs • Four (4) private offices plus CEO suite • Open office area, shared office, and huddle room • Conference room, reception, and break room with pantry • Dedicated server room • Shipping/receiving with freight elevator access

Date on Market:

2026-03-25

Cambridge Office for Lease - Mid-Cambridge/Harvard Sq

This office property is situated on Cambridge Street in the Wellington-Harrington neighborhood, offering a high-visibility address in the heart of Cambridge. The available suite features a functional layout with three private offices, a reception area, a kitchenette, and a private restroom, designed to complement professional and creative work environments. Natural light enhances the space, while the secured building ensures privacy and reliability for occupants. The location provides seamless accessibility via public transportation and is exceptionally walkable, with bike-friendly routes nearby. Tenants benefit from proximity to leading universities, medical facilities, and biotech firms that define Cambridge’s dynamic business ecosystem. Positioned within a well-connected district, the property serves as a strategic hub for companies seeking connectivity to Kendall Square, downtown Boston, and the broader Greater Boston market.

Date on Market:

2026-03-09

Medford Flex, Industrial for Lease - Medford/Malden

Ware Street Workspaces is a new kind of workspace, offering warehousing with Class A amenities, coworking facilities, and individual workspaces that allow businesses to grow and operate more efficiently. Whether in need of space for warehousing, product assembly, office use, storage, or even light manufacturing, each workspace is fully adaptable to meet unique business needs. With Ware Street Workspaces flexible and customizable workspaces, businesses can reimagine their commercial real estate needs and consolidate office, warehouse, shipping/receiving, and storage operations under one roof. The property is conveniently located half-mile from the MBTA, Assembly Row, Tufts University, and other Medford, Cambridge and Boston destinations.

Date on Market:

2026-03-03

Newton Office, Retail for Lease - Newton/Brookline

Multiple spaces for lease ranging from 1,456 - 3,717 SF and 1,256 - 2,138 SF • Ground floor of a 173,000 SF office building leased to various institutional companies such as Clearview Healthcare Partners and Odysseys Unlimited. • Existing (shared) parking deck containing 344 spaces in addition to ample street parking and an abutting 67 space public parking lot • Ground-Level co-tenants include Pediatrics of Newton Wellesley, Corepower Yoga, Sola Salon and Thai Amarin • Located directly at the heavily trafficked confluence of the Massachusetts Turnpike, Washington Street and Centre Street • Positioned in the Newton Corner village of Newton, and directly engrained in the interior residential road network in addition to its ideal ingress/egress from various access points

Date on Market:

2026-06-03

Waltham Office for Lease

Property Type:

Flex

Date on Market:

2026-02-20

Newton Office for Lease - Newton/Brookline

Located in the heart of Newton Corner, 275 Washington Street—commonly known as One Newton Place—is a prominent Class B, four-story office and retail building totaling approximately 173,000 square feet. Originally built in 1985 and renovated in 2005, the property offers a flexible mix of office and ground-floor retail space suited for professional, medical, and service-oriented tenants. The building features efficient floor plates, approximately 12-foot unfinished ceiling heights, and a strong on-site and nearby amenity base. Strategically positioned at the highly trafficked confluence of Washington Street, Centre Street, and the Massachusetts Turnpike (I-90), the property provides exceptional regional accessibility, including express bus service to Boston and convenient highway access. Tenancy includes a mix of established corporate, healthcare, and lifestyle users, contributing to a vibrant, walkable environment within one of Newton’s most connected commercial villages.

Date on Market:

2026-02-17

Woburn Flex for Lease - Burlington/Woburn

Date on Market:

2026-01-27

Andover Flex for Lease - Lawrence/Andover

Date on Market:

2026-01-13

Stoughton Office for Lease - Route 24

100 Technology Center Drive is a well-located commercial property within a established suburban office and technology park in Stoughton, Massachusetts. The building offers a professional corporate environment with convenient access to major regional highways, supporting efficient connectivity to Greater Boston and surrounding markets. Designed to accommodate a range of office, R&D, or light industrial uses, the property benefits from ample on-site parking, landscaped surroundings, and proximity to local amenities, making it an attractive option for technology-focused and professional tenants.

Date on Market:

2026-01-06

Waltham Office for Lease

Date on Market:

2025-12-17

Malden Office for Lease - Medford/Malden

11 Dartmouth Street is a newly constructed 188,000 square foot Class A multi use building designed to accommodate office medical research and development and life science tenants. The property offers highly flexible floor plates up to 20,000 square feet and features a best in class amenity package including indoor and outdoor common areas an onsite fitness center tenant event spaces 138 parking spaces and 80 bike storage spaces. The building is designed for wellness and efficiency with abundant natural light panoramic views and convenient access to the Malden Center MBTA Station. With modern infrastructure multiple passenger and freight elevators and lab ready building systems 11 Dartmouth Street provides a future focused environment ideal for innovative organizations.

Date on Market:

2025-11-17

Boston Office for Lease - Seaport

Located in Boston’s vibrant Seaport District, 19 Fid Kennedy Avenue is part of The Foundry at Drydock, a premier Class A office building offering approximately 250,959 square feet of modern workspace. Built in 2022, this eight-story property features state-of-the-art design, controlled access security, and on-site staff, making it ideal for businesses seeking a dynamic and secure environment. The building includes biotech and lab-ready spaces, waterfront views, and easy access to public transportation, dining, and entertainment options, creating an inspiring setting for innovation and collaboration.

Date on Market:

2025-11-10

Lexington Flex for Lease - Lexington/Arlington

Located in Lexington’s thriving life sciences corridor, 60 Westview Street is a Class A commercial building offering approximately 40,200 square feet of flexible lab and office space. Originally built in 1975 and renovated in 2002, the property sits on a 3.76-acre lot and is zoned for industrial/general use.

Date on Market:

2025-11-10