178 Life Science Properties for Lease in Massachusetts, USA

Cambridge Office for Lease - Mid-Cambridge/Harvard Sq

The Abbot at 18-24 Brattle Street presents a once-in-a-generation opportunity to occupy the most iconic building in the heart of Harvard Square, the epicenter of Cambridge, Massachusetts. Future tenants are invited to discover the tremendous redevelopment potential of this iconic property through a blend of historic preservation with modern amenities. World-class academic institutions, top tech and life science companies, vibrant neighborhoods, and rich cultural diversity surround this dynamic property. Completely renovated from the inside out, suites on the second and fourth floors are immediately available for lease. The building's diverse tenant mix includes creative and professional businesses and national tenants, such as Starbucks, Cava, and F45 Training. Occupancy terms are negotiable, with lease rates available upon request. Building tenants enjoy state-of-the-art HVAC, private outdoor space, operable windows, and more. Historical and cultural offerings, cobblestone streets, and a unique blend of over 350 dining, retail, and entertainment options within a quarter-mile encompass The Abbot. This section of Cambridge is one of the most iconic locations in the market and one of the most accessible. Situated directly across the street from Harvard Square Red Line Station, the third-most active station in the area, tenants have access to over 23,000 daily riders. The Abbot boasts unparalleled traffic and amenities, making it a draw for customers, businesses, and retailers alike.

Date on Market:

2024-06-24

Tewksbury Office/Medical for Lease - Lowell/Chelmsford

A medical office building is conveniently situated just off Route 495 at Route 38. It’s modern, comfortable, and close to various amenities, with a very short drive to downtown Lowell. The building offers plenty of parking, and the first floor houses an LGH lab and X-ray services.

Property Type:

Office

Date on Market:

2022-09-07

Cambridge Office for Lease - Mid-Cambridge/Harvard Sq

Available immediately. Premier office/flex space in Cambridge on Sidney St in the heart of MIT. An entire campus for your company composed of two buildings, and featuring dedicated parking spaces. Free-standing buildings ensures that you have not just a private space for your company, but that you also make a strong statement by not having to share your building with any other group and it allows you extraordinary signage opportunities on your own campus; a true rarity in Cambridge. Perfect for life science and technology companies. SD-8 Zoning allows office, lab, R&D, light industry (including manufacturing), educational purposes (including dormitory), medical and health care use, local government use. The building features two floors, and is composed of a mix of closed offices, open spaces, multiple conference rooms, large kitchen area, and multiple bathrooms featuring showers, a dedicated mother’s room, and ample natural light. The space was completely renovated two years ago and has been 100% transformed at that time with the building brought back to the shell, and transformed into an exceptional 1st class setting which was formerly the corporate headquarters for a public life science company. Modern, bright, and functional with careful attention paid to even the smallest details. Architecture designed by Margolis & Fishman; construction performed by Siena. Easily accessible by public transportation, and it has multiple public parking spaces on the street, and there are fifteen dedicated parking spaces as well. A rare opportunity to lease premier space in stand-alone buildings by Central Square, and MIT. Multiple public life science companies are located on Sidney St, and it remains a highly desired area with numerous public companies surrounding it. Open to short and long term leases. Furniture can be left in place for plug and play. All brokers are protected.

Date on Market:

2024-08-16

Worcester Office for Lease - Worcester Metro

Situated on the bustling UMass Chan Medical School Campus, 403 Belmont Street is a state-of-the art medical facility boasting approximately 108,750 +/- SF of rentable area on 4 floors. The building includes an attached garage with a covered walkway connected to the 3rd floor, allowing for seamless patient and employee access. Ratio for parking is 4 / 1,000 SF. Tenants of 403 Belmont Street have access to the cafe and fitness center, located at the Albert Sherman Center. The Veteran Affairs (VA) outpatient clinic of Worcester occupies more than 50,000 SF within the Class A medical office building. The outpatient clinic offers primary care and specialty health services including laboratory services, physical therapy, nutrition counseling, radiology, and more. At 403 Belmont Street, 38,646 +/- SF remain available for lease on two floors, which can be subdivided to accommodate tenants from 5K SF and above. The space is ideal for vibrant medical practices looking to grow and expand.

Date on Market:

2022-10-21

Worcester Office for Lease - Worcester Metro

UMass Medicine Science Park is one of the nation’s leading centers for biotechnology research and production, providing a nurturing environment for companies during all stages of growth. Ranging from start-up incubator space to full-building footprints, the five-building park accommodates a variety of quality office and laboratory tenants within an extraordinary 10-acre campus setting. The nearly 470,000-square-foot park is home to dozens of biotechnology companies, as well as several non-profit and academic institutions. Situated alongside the continuously growing UMass Medical School and UMass Memorial Medical Center campus, the UMass Medicine Science Park both contributes to and benefits from the organic synergies created within this interconnected complex. A palpable energy from an unparalleled 10,000+ knowledge seekers on site – in addition to approximately 10 additional neighboring colleges and universities – permeates the campus, encouraging innovative thoughts and collaborative partnerships. Situated on a scenic green hilltop, UMass Medicine Science Park’s collaborative, campus setting offers tenants cutting-edge resources and ample amenities. Conveniences include: • Campus cafeteria • Campus fitness center • Plantation Street parking garage • UMass Medical School Library • Conference facilities • Beechwood Hotel & Conference Center (adjacent) • Access to Research Core facilities

Date on Market:

2024-07-15

Boston Industrial for Lease - Seaport

310-312 North Avenue is a class B industrial building that offers refrigerated industrial condominiums in Boston, MA. The 48,882 square foot building has 26,000 square feet, split between 2 condos, available for sale or lease. The building is conveniently located near two bus lines and eight-minutes away from the Boston Logan International Airport, providing easy access for commuting. Additional to the commuter options, the building Is also within a one to eight-minute drive to eight hotels in the area. Tenants can enjoy industrial spaces with cross docks, refrigeration, and redevelopment opportunities. Employees will find themselves within driving distance of restaurants and banks.

Date on Market:

2024-06-20

Watertown Office for Lease

Date on Market:

2024-03-26

Walpole Multiple Space Uses for Lease - I-95 Corridor South

Mixed-use campus ideal for office, R&D, lab, light industrial, and storage uses. Former mill converted into a modern business park with brick and beam finishes. Plentiful on-site parking available. Conveniently located within walking distance of the amenities in Downtown Walpole/MBTA Station. Flexible floor plates. Ample power for flex/light manufacturing users. Loading docks and freight elevator

Date on Market:

2024-12-04

Worcester Flex for Lease - Worcester Metro

20 Reactory Drive and 30 Reactory Drive are adjacent lots with permits in place. By combining these two parcels, The Reactory can accommodate from 95,000 to 380,000 square feet with parking on the combined lots. This allows for companies to design and construct a facility that meets their needs today and expansion for future growth. 31 Reactory Drive is the largest parcel on the campus. With over 24 acres of land, this site can accommodate a large-scale operation in one or multiple buildings. This is an ideal site for those companies that need significant size to start but even more for their growth in the future. With endless flexibility, The Reactory offers companies the ability to scale its operations as their business evolves. • 46 acre life sciences campus • 3 land parcels that can be subdivided or combined • Site can accomodate 70,000 square feet to over 1,000,000 square feet • Permits in hand • Foundation in place at 20 Reactory Drive • 100% support from The Commonwealth of Massachusetts and the City of Worcester • A proven location for Life Sciences Grow with us. Let The Reactory in Worcester be your next move.

Date on Market:

2024-02-29

Medford Office/Medical for Lease - Medford/Malden

One Cabot Road is a four story, ±316,233 SF class A office building located in the thriving community of Medford, Massachusetts. The property recently underwent a $16.9 million amenity upgrade and now features a new lobby lounge, coffee lounge, new fitness center and locker rooms, expansive outdoor patio and a full-service cafe.

Property Type:

Office

Date on Market:

2024-02-23

Cambridge Office for Lease - Mid-Cambridge/Harvard Sq

Date on Market:

2023-11-29

Hudson Flex, Industrial for Lease - Concord/Maynard

Date on Market:

2024-07-01

Marlborough Office, Flex for Lease

Avison Young is pleased to present for lease 100 Crowley Drive in Marlborough, MA. Located immediately off of I-495 via Exit 25A, 100 Crowley Drive offers unparalleled access to both I-495 and I-290 via the Route 85 Connector. Built in 2010, the building offers a contemporary high-tech feel and features a two-story grand lobby with maple and stainless steel finishes

Date on Market:

2024-06-11

Burlington Office for Lease - Burlington/Woburn

Date on Market:

2023-10-16

Cambridge Office, Flex for Lease - Mid-Cambridge/Harvard Sq

Date on Market:

2025-09-29

Beverly Office for Lease - Danvers/Beverly

Build-to-suit office suite with extensive window line overlooking wooded campus. Private shared community break area and restrooms.

Date on Market:

2025-04-09

Milford Retail for Lease - Outlying Worcester

Granite Hill Marketplace is an ideally positioned retail center with flex/warehouse potential in Milford, Massachusetts. Situated on 16.4 acres off Fortune Boulevard, the development totals 97,095 square feet across an upper lot big-box retail building with a big-box retail building and restaurant on the lower portion of the parcel. Space is available immediately for occupancy, with property features that include ample surface parking, over 22-foot ceiling clear heights, full air conditioning, tailboard loading docks, exceptional Interstate 495 visibility, and more. The center is situated within the Highway Industrial (IB) District of Milford and allows for a variety of uses. Benefit from incredible building adaptability for retail, office, manufacturing, production, life science research and development, bio-manufacturing/cGMP, data center, medical and many other uses. Plus, Granite Hill Marketplace is directly adjacent to major anchors such as Target and Lowe’s. Granite Hill Marketplace sits 30.3 miles southwest of Downtown Boston and 32.7 miles north of Providence, Rhode Island. Experience seamless connectivity to major highway systems and population centers with strategic access to Interstate 495 in a half mile and reach Route 9, Interstate 90, and Interstate 95 within minutes. A growing population of nearly 137,000 residents lives within a 15-minute drive from the property, representing an average household income exceeding $150,000 annually in addition to the yearly consumer spending of $4.5 billion dollars. Annual consumer spending within a mile is averaged at $16.1 million dollars.

Date on Market:

2025-04-28

Boston Office for Lease - Financial District

Office building located in prime Boston location. Close to many public transportation options.

Date on Market:

2025-08-06

Cambridge Retail for Lease - E Cambridge/Kendall Sq

Immediately north of the site is Cambridge Crossing, a new 43-acre development located at Lechmere Station home to Philips, Bristol Meyers Squibb, REI, Tatte, and Lamplighter Brewing

Property Type:

Office

Date on Market:

2025-11-17

Chelsea Office for Lease - Chelsea/Revere

Tons of area amenities within walking distance from the property. Highly attentive property management. Cost effective office space that Landlord is willing to build out for potential tenants to their required specs. Immediately accessible to the commuter train station, just one stop to North Station. Bus service to Wellington (orange), Haymarket (green) and Wonderland (blue) immediately accessible. Boston Logan International Airport just minutes away. Easy on/off Routes 1, 93 and 16.

Date on Market:

2025-09-02

Framingham Flex for Lease - Framingham/Natick

On behalf of our client, CBRE is pleased to present an exciting opportunity at 111 Lawrence Street in Framingham, Massachusetts. Recently renovated in 2008, the building offers ±84,420 SF of Class A office space. 111 Lawrence Street is conveniently located minutes off Route 9, provides immediate access to the Massachusetts Turnpike (I-90) and is a 30-minute drive from downtown Boston and Logan International Airport. Located in the heart of MetroWest, Framingham has superior identity and outstanding design for companies seeking a corporate location in a first class office building with unparalleled on/off access to the Mass Pike. Area amenities include many restaurants, fast food and retail options, including Shoppers World, Natick Mall and an upscale Life Time Fitness facility. Local hotels include Crowne Plaza, Hampton Inn, and Courtyard Marriott.

Date on Market:

2022-10-24

Peabody Flex for Lease - Peabody/Salem

Property Type:

Office

Date on Market:

2022-02-02

Burlington Office for Lease - Burlington/Woburn

Date on Market:

2023-02-09

Boston Office for Lease - Seaport

Seaport Circle is a mixed-use development featuring 650,000 square feet of life science research and office space in Boston's most prominent life science cluster. The project is pursuing LEED Platinum designation, with a 90% reduction in natural gas use. The two-tower design will provide flexible floor plates ranging from 25,000-75,000 square feet. In addition to state-of-the-art Class A lab and office space, the building will include best-in-class tenant amenity spaces and approximately 5,000 square feet of retail space. Seaport Circle will also include a 15,000 SF stand-alone South Boston Waterfront Job Training Pavilion (the Pavilion) with an ambitious mission focused on training for skilled jobs in life sciences and adding talent to the pipeline of opportunity in the Boston area’s exploding life science sector.

Date on Market:

2023-02-06