188 Life Science Properties for Lease in Massachusetts, USA

Woburn Flex for Lease - Burlington/Woburn

Building features & amenities: The property provides plenty of free parking. On-site management is available at your convenience. There is in-house design and construction teams available. A bustling business park close to restaurants, retail stores, banks, daycare facilities, fitness facilities, medical offices, dry cleaning services, salons, and hotels.

Date on Market:

2026-01-27

Waltham Flex for Lease

CALL FOR OFFERS | MAY 12TH, 2026 This is a prime opportunity to acquire a commercial asset. This property is centrally located in a desirable part of town, boasting quality neighboring tenants. The lot offers high visibility. This area has a high traffic count and heavy daytime traffic. The amenities offered at this location make this a priceless commercial venture.

Date on Market:

2023-03-31

Woburn Flex for Lease - Burlington/Woburn

At the intersection of I-93 and I-95 (Route 128) in Woburn, Olympia Avenue is a compelling option for employers seeking quality office and laboratory space in a central location at a great value. A variety of local amenities – including shopping and dining at Woburn Village, hotels, recreational activities, and professional services – are just minutes away.

Date on Market:

2026-02-24

Peabody Office, Industrial for Lease - Peabody/Salem

Colliers International is please to announce over 20,000 square feet of first class office/industrial space for lease. Located in the prestigious Centennial Park in Peabody, this is an ideal location for a high tech user. Built in 1995, the building lends itself to a variety of uses including R&D, medical, manufacturing, distribution and biotech. 300 Jubilee Drive is located off Route 128 within a quarter mile from Route 1 and the I-95/Route 128 interchange. It is 20 minutes north of Logan International Airport and next to the North Shore shopping centers. Its corporate neighbors include Children' s Hospital, Analogic, Christian Books, Cardinal Health, Avnet, and a full service Marriott Hotel.

Date on Market:

2025-03-20

Boston Office for Lease - Newton/Brookline

Date on Market:

2025-12-09

Lexington Office for Lease - Lexington/Arlington

The five-building campus totals 360,000 SF of office space. With a full complement of area amenities, the campus is adjacent to Hanscom Air Force Base and is easily accessible from all directions.

Date on Market:

2024-12-11

Lawrence Multiple Space Uses for Lease - Lawrence/Andover

Heritage Place, situated on 8 acres of land, is ideal for medical office, R&D and professional users interested in flexible terms and aggressive rental rates. The building has newly renovated tenant and common areas featuring over-sized windows, exposed brick and classic post & beam construction with generous 24 x 24 column bay spacing. There is food service and day care available on site with many retailers and restaurants located within walking distance. Heritage Place is on the Andover/South Lawrence line, .5 mile from I-495,1.5 miles from I-93 and just 25 miles to Boston. An excellent location with easy highway access to the greater Merrimack Valley and southern New Hampshire, the property is convenient to public transportation and also offers free on-site parking at an estimated ratio of 3 cars per 1,000.

Date on Market:

2025-07-30

Springfield Land for Lease - Hampden County

The property at 20 Wason Ave, Springfield, MA 01107-1132 is a commercial space situated on a 5-acre lot. This vacant land offers significant potential for development, making it an attractive option for various commercial ventures. Located in a strategic area of Springfield, the property benefits from easy access to major roads and local amenities. The site is currently available for lease, providing a prime opportunity for businesses looking to establish a presence in the region.

Property Subtype:

Commercial

Date on Market:

2025-04-18

Somerville Retail for Lease - Somerville/Everett

Property Type:

Multifamily

Date on Market:

2026-02-20

Allston Office/Medical for Lease - Allston/Brighton

Dexter 200 at 200 Dexter Avenue offers a modern and highly adaptable environment designed to meet the needs of innovative businesses. This two-story flex property combines office and state-of-the-art life science lab space with suite sizes ranging from incubator labs to full offices. Labs come fully equipped with essential research infrastructure, including biosafety cabinets, freezers, fume hoods, and centrifuges, as well as shared conference rooms, a stocked break area, and private offices in select suites. Tenants benefit from specialty support services such as bio-waste removal, safety training, and compliance assistance, plus on-site EHS and lab operations support. The building provides convenient on-site parking, secured 24/7 access, and collaborative spaces to accommodate a range of professional and research-driven enterprises. Located just off Arsenal Street in East Watertown, Dexter 200 delivers unmatched connectivity to Soldiers Field Road, the Mass Pike (I-90), and Route 128 and is minutes from Cambridge, downtown Boston, and Logan Airport. Public transportation via the #70 bus is within close reach, and the property is surrounded by retail, dining, and lifestyle amenities at nearby Arsenal Yards. Dexter 200 is an ideal destination for life science startups, R&D companies, and growing businesses seeking a well-positioned space in Greater Boston’s innovation corridor.

Property Type:

Flex

Date on Market:

2024-09-18

Westborough Office for Lease - The Boroughs

Property Type:

Flex

Date on Market:

2024-05-29

Westford Office for Lease - Lowell/Chelmsford

Setting the market standard for office, flex, and research and development use, Westford Tech Park offers businesses an unrivaled campus experience in Westford, Massachusetts. Family-owned and developed with care since 1990 by the same dedicated team, the park provides a level of consistency and commitment unmatched throughout the Boston metropolitan area. Experience the difference of engaged ownership that makes tenant needs a top priority. The multiple-building Westford Tech Park stretches across 85 acres and has attracted and retained high-intellectual companies in the defense software computing, aerospace engineering, and computer networking sectors for the past three decades. In addition to many of the original tenants that remain at the site, the campus today is home to industry-leading AI, cloud computing, and internet software firms. A connected campus atmosphere fosters collaboration and community, transforming this workplace into a vibrant hub of activity and innovation. Flexible space solutions for a variety of users are available for occupancy in move-in-ready and spec conditions. Westford Tech Park offers a range of amenities both inside and outside the park. Inside, discover modern facilities and services designed to enhance the workday with full-service cafés, well-equipped fitness centers with lockers and showers, recent property upgrades, significant power availability, and more. Step outside, and a serene park setting awaits, perfect for unwinding during and after the day. Located 35 miles northwest of Boston, Westford Tech Park ensures a cohesive and well-maintained environment with convenient highway access for easy commuting. Reach the Route 3 and Interstate 495 interchange within an eight-minute drive, the Massachusetts-New Hampshire border in 18 minutes, and Boston Logan International Airport in 45 minutes. Westford Tech Park is serviced by Lowell Regional Transit Authority buses near national businesses and points of interest, such as Dunkin’, Whole Foods, Chase Bank, the Nashoba Brook Watershed Trails hiking area, and more.

Date on Market:

2024-07-12

Waltham Flex for Lease

Recently built R&D sublease opportunity now available in the Waverley Oaks Park in Waltham. Waltham has become a lively hub of Robotics, Life Science, and traditional office users. Waverley Oaks Park houses a fusion of industries including numerous retail establishments within walking distance; offering options for food, fitness, and services. This unique R&D/flex opportunity provides companies a flexible solution to immediately occupy and establish themselves within a growing business cluster in an innovative market along Route 128.

Date on Market:

2023-09-18

Waltham Flex for Lease

Waltham Research Park is a three building 210,000 square foot Office/Lab/and light manufacturing Park. Located in the heart of Waltham’s research cluster, Waltham Research Park’s Corporate neighbors include Sanofi-Genzyme, Thermo- Fisher Scientific, Massachusetts General Hospital and many more. The Park’s existing tenants are QinetiQ Inc, BioModels, Boston Dynamics and Snapdragon Chemistry. 350 Second Avenue, one of three buildings in the Park, is undergoing major renovations. Consisting of approximately 40,013 sq ft, 350 Second Ave is suited for users in Laboratory Sciences and other fields down to research and development. Building to be brought up to current life safety standards, including a new elevator to service the building’s two story section.

Date on Market:

2025-09-08

Waltham Office for Lease

Date on Market:

2026-03-02

Needham Office for Lease - Wellesley/Needham

An affiliate of Bulfinch purchased the site of the former Muzi Ford Dealership on Highland Ave in late 2021 with plans to redevelop the 10 +/- acre site into a new state-of-the-art facility to support market demands for life science, research and development space. The site’s highly visible location on Rt 128/ 95 is an attractive opportunity for a headquarters location at the gateway to Needham. The site benefits from its close proximity to the MBTA Commuter Rail, under a mile away, as well as recent area infrastructure improvements including an additional RT 128/ 95 lane, new bike lanes and bridge widening, all of which support more commuting options and enhance the commuter experience for future tenants.

Date on Market:

2026-02-23

Hopkinton Office for Lease - Hopkinton/Holliston

Date on Market:

2026-03-19

Boston Office for Lease - Longwood/Fenway

JLL is pleased to bring to market 13,363 SF of newly built and furnished lab and office space at 20 Overland Street in Fenway. The five-story building is conveniently located in the core of Longwood Medical Area with close proximity to the MBTA Green Line as well as the Mass Pike and Storrow Drive. The building is surrounded by retail amenities and includes collaboration areas and a private roof deck on-site.

Date on Market:

2025-10-02

Waltham Flex for Lease

Date on Market:

2025-09-23

Cambridge Office for Lease - E Cambridge/Kendall Sq

Located in the heart of Kendall Square, 250 Binney Street is a distinguished Class B office building offering approximately 67,362 square feet of premium workspace across two stories. Originally constructed in 1983, the property features typical floor plates of 33,681 square feet, with 12-foot unfinished ceiling heights that provide a spacious and flexible environment suitable for a variety of tenants, including biotech and lab users. Tenants benefit from 24-hour access, a security system, and proximity to public transit including bus lines and the metro/subway. On-site amenities include a restaurant, property management, and 1,100 covered parking spaces, ensuring convenience and comfort for employees and visitors alike. The building is currently available for lease and is managed by JLL, making it an ideal opportunity for businesses seeking a strategic location in one of Cambridge’s most dynamic commercial hubs.

Date on Market:

2025-08-04

Westwood Office for Lease - Route 1 South

Date on Market:

2025-06-09

Waltham Office for Lease

41 Seyon Street is a part of a newly renovated office and R&D park. The property's prime location provides easy access to an extensive array of additional amenities within walking distance.

Property Type:

Flex

Date on Market:

2025-03-06

Worcester Office for Lease - Worcester Metro

55 Union Street is strategically located within walking distance of the amenity-packed Downtown Worcester area.

Date on Market:

2025-02-14

Somerville Office for Lease - Somerville/Everett

101 South Street is speculative lab building in the Boynton Yards industrial area of Somerville, MA. Located adjacent to Union Square and only one mile from Kendall Square, the City of Somerville plans for Boynton Yards to be redeveloped into a vibrant, mixed-use district comprised of lab, office, multifamily and neighborhood retail and community arts space.

Date on Market:

2025-04-03