447 Life Science Properties for Lease in California, USA

Palo Alto Office for Lease

Situated in Palo Alto’s premier innovation corridor, benefiting from unparalleled accessibility to California Avenue’s diverse retail and dining amenities, as well as the connectivity afforded by Caltrain, regional commuter shuttles, bike paths, and Stanford Research Park’s robust transportation network. A 2.5/1,000 parking ratio further supports commuting flexibility for a variety of workforce profiles. Together, these advantages position 3100 Hansen Way as an exceptional opportunity for companies seeking a refined, amenity-rich, and highly efficient headquarters-quality environment at the heart of Silicon Valley’s most prestigious research park

Date on Market:

2026-02-17

Irvine Flex for Lease - Irvine Spectrum

This 96,000-square-foot freestanding flex/R&D building is divisible between 24,000 to 96,000 square feet. It is elevator served and has 5,000 square feet of climate-controlled warehouse space with 1 ground-level loading door. Furniture, fixtures, and equipment are available. The building features a dramatic lobby with 48,000 square feet of 2nd floor executive office space including a fitness center and large training room. 3,000 amps 277/480V power with on-site generator and battery backup system for uninterrupted power. Excellent for advanced manufacturing uses. Turn-key R&D lab space is on the first floor with C-arm, chem, and bio-hazard lab. 100% climate controlled facility with freezer and cooler space capabilities. The site features 384 parking stalls for a 4:1,000 parking ratio. Parking is expandable to accommodate larger companies. Property is institutionally owned. Longer lease term possible.

Date on Market:

2026-02-05

South San Francisco Flex for Lease

The location delivers immediate connectivity to Highway 101, with quick links to Highway 380 and 280. Caltrain’s South San Francisco station is walkable, the South San Francisco Ferry Terminal is nearby, and San Francisco International Airport is roughly a 10-minute drive. Downtown San Francisco is approximately 20 minutes away. The site is surrounded by nationally recognized life science campuses, including Gateway of Pacific, Kilroy Oyster Point, and Genentech, giving tenants proximity to talent, suppliers, and collaborators. As a freestanding building with on-site parking and a backup generator with ample power, 425 Eccles Avenue suits single-tenant occupancy or can be configured for multiple users seeking efficient lab and office space in a premier Bay Area innovation market.

Date on Market:

2026-02-02

Palo Alto Office for Lease

New For Lease! - Great Flex / R&D (Lab Benches Can Be Removed) - Secured Yard - Double Door - Great Flex Space and Private Offices - Close To Hwy 101 & Central Expressway. - Conference Room and Privates - Improvements Available **CAN BE LEASED WITH NEIGHBORING BUILDING FOR 11,000 SF** - 795 San Antonio Road +/- 6,800 SF - 797 San Antonio Road +/- 4,200 SF TOTAL = 11,000 SF Available

Date on Market:

2026-01-29

Palo Alto Office for Lease

New For Lease! - Great Flex / R&D (Lab Benches Can Be Removed) - Roll-up Door - Fenced Parking - Close To Hwy 101 & Central Expressway. - Conference Room and Privates - TI Available! **CAN BE LEASED WITH NEIGHBORING BUILDING FOR 11,000 SF** - 795 San Antonio Road +/- 6,800 SF - 797 San Antonio Road +/- 4,200 SF TOTAL = 11,000 SF Available

Date on Market:

2026-01-29

San Diego Office for Lease - Sorrento Mesa

Property Type:

Flex

Date on Market:

2026-01-29

Santa Fe Springs Industrial for Lease - Southeast Los Angeles

Date on Market:

2026-01-26

South San Francisco Flex for Lease

±17,000 SF 2-story building with ±30,492 SF lot and ±49 parking spaces.

Date on Market:

2026-01-23

San Francisco Office for Lease - Yerba Buena

Date on Market:

2026-01-21

San Diego Flex for Lease - UTC

• ± 96,500 SF standalone flex/creative/R&D building on 6.55 acres in the heart of San Diego’s UTC innovation hub (± 18,000 SF of Office, ± 78,500 SF of Flex/Industrial) • Secure, campus-style setting with on-site amenities, surface parking, and controlled access • Highly efficient floor plates ideal for single-tenant HQ, design studio, R&D, or innovation lab uses • Amenities: on-site fitness center with showers and lockers, outdoor tennis and volleyball, creative and social spaces designed to inspire

Date on Market:

2026-01-16

Sunnyvale Industrial for Lease

Nestled in the dynamic and innovation-driven city of Sunnyvale, 388 Oakmead Parkway offers an exceptional opportunity for businesses looking to thrive in one of the most sought-after locations in the Bay Area. With convenient access to major tech campuses, highways, and public transit, this property combines modern functionality with strategic positioning. Dedicated Lab with 10 Racks • Can operate 10 H200 GPUs, Management Nodes & Petabyte Storage Clusters • 1 megawatt of power to building • Enough power available to expand to a full B200/B300 GPU Cluster • Each rack includes two 208V 3 phase 48A PDUs

Date on Market:

2026-01-15

Hayward Flex for Lease - Hayward/Castro Valley

The property at 22421-22429 Hesperian Blvd, hayward is an exquisite, free-standing biotech, lab, and office building offering approximately 8,465 square feet of versatile space. Designed to accommodate both laboratory and office functions, the building can be demised into two separate units, providing flexibility for a range of tenants. Key features include lab spaces with benches already in place, enhanced BSL2 capabilities in one lab, nearly new roof and solar panels, modern HVAC packages, and perimeter security fencing. Monument signage is available for full-building users, and abundant parking supports both staff and visitors. The property is strategically located near the Hayward Executive Business Jet Airport and US 880, making it highly accessible for business operations. Additionally, the building is offered for lease with an option to buy, providing future ownership opportunities for interested parties.

Date on Market:

2026-01-09

Brisbane Office for Lease - Brisbane/Daly City

1800 Sierra Point 2nd floor office space. New office build out. Located in the center of the Bay Area life science cluster.

Property Type:

Flex

Date on Market:

2026-01-07

Carlsbad Flex for Lease

Date on Market:

2026-01-05

San Diego Office/Medical for Lease - Kearny Mesa

Coast Medical Center, located at 3444 Kearny Villa Road, is an attractive medical office building in San Diego that offers high visibility from Interstate 805, just south of the Highway 163 junction. The four-story facility features recently updated common areas and façade, a courtyard, a ground-level surgery center, and a broad selection of turnkey suites. Coast Medical offers ample parking and a centralized location for patient convenience, as well as opportunities for monument and building signage to capitalize on the site’s excellent exposure. Approximately a half mile to Sharp Memorial Hospital and Rady's Children's Hospital, Coast Medical Center is in an established healthcare node to provide support services and expand referral networks. Area residents prioritize health and wellness, and report high incomes, forming an ideal patient pool. Underscoring this, an average annual household income of $110,907 contributes to more than $263 million in yearly healthcare spending within a 5-mile radius. Remedy Medical Properties is a leading owner and operator of outpatient medical real estate, delivering integrated services across investments, development, leasing, management, and strategy. We own and operate medical office properties so healthcare providers can focus on patient care. Remedy specializes in the leasing of medical office space and outpatient medical buildings for physicians, health systems, and medical groups nationwide. Our team works directly with providers to deliver flexible space solutions that support clinical operations, patient access, and long-term growth. Learn more at remedymed.com.

Property Type:

Office

Date on Market:

2013-09-20

Carlsbad Flex for Lease

Date on Market:

2025-12-18

San Diego Office/Medical for Lease - Uptown West/Park West

Signature medical/office opportunity in Bankers Hill new development with building signage and co-tenancy with UCSD and iStrive Research Lab This building is one of the few in the market that fully meets the 2030 State-required ASCE 41 earthquake standards—qualifying it for all State tenants and any tenant serving State employees, patients, or visitors 24/7 access with controlled entry and an advanced security system One of San Diego’s most desirable walkable neighborhoods with a dense population and breathtaking views of Downtown San Diego Bay, Point Loma, and the Pacific Ocean Exposure to adjacent neighborhoods including Little Italy, Balboa Park, Hillcrest, Mission Hills, and Downtown Located on the main thoroughfare connecting Balboa Park to I-5

Property Type:

Office

Date on Market:

2025-12-09

South San Francisco Office for Lease

650 Gateway Blvd South San Francisco, CA R&D building with ample lab space.

Date on Market:

2025-12-09

Yuba City Office, Industrial for Lease - Sutter County

1200 Putman Avenue in Yuba City, California, is a well-maintained, concrete tilt-up industrial facility totaling approximately 37,500 square feet of warehouse space with additional mezzanine and second-floor laboratory areas. The building also includes 4,500 square feet of office, supported by generous on-site parking. Situated on 3.7 acres, the property offers efficient circulation, ample truck and trailer parking, and secure site access through key-code entry gates. The warehouse features 31-foot clear height throughout, multiple electric and manual roll-up doors, and four recently installed truck docks with self-levelers. The roof was replaced approximately three years ago. The facility is equipped with substantial power capacity, suitable for a wide range of industrial or production uses. Most recently operating as a quinoa processing facility, the building met full FDA food-grade standards and has benefitted from over $1 million in upgrades within the past three years, including extensive improvements to meet food-grade operational requirements. Its location provides convenient regional access—5 minutes from Highway 99, 10 minutes from Highway 20, and approximately 40 minutes to Sacramento and Sacramento International Airport. Monument signage opportunities further enhance visibility for users seeking a strong presence. Overall, 1200 Putman Avenue offers a modern, secure, and highly functional facility well suited for food-grade operations or other specialized industrial uses requiring power, clear height, loading, and site efficiency.

Date on Market:

2025-12-08

Redwood City Office for Lease

Strategically positioned in the heart of Silicon Valley, 700 Bay Road offers flexible space for a variety of users. This location is an ideal landing spot for growing life science and R&D companies. The cutting-edge mix of laboratory and office space is specifically designed for innovation. There are extensive laboratory facilities for biology labs, automation labs, vivarium, and tissue culture. This particular location is ideal for employees and visitors coming to the property. It is centrally located near many major universities, creating a substantial labor pool.

Property Type:

Flex

Date on Market:

2025-12-08

Berkeley Industrial for Lease

Berkeley Forge stands as Berkeley’s largest campus for deep tech, tough tech, and manufacturing innovation. The property comprises five buildings—1314, 1320, 1330, 1401, and 1420/1421—each designed for high-power, advanced manufacturing and R&D. The site benefits from proximity to UC Berkeley and the Gilman District, offering access to a diverse talent pool and vibrant amenities including breweries, wineries, art galleries, and retail. The property’s history is rooted in Berkeley’s manufacturing heritage, now revitalized with a focus on sustainability and knowledge-intensive production. Corporate neighbors include leading biotech, energy, and technology firms, reinforcing the campus’s position at the intersection of academia and industry. Berkeley Forge is ideal for organizations seeking a collaborative, future-ready environment in a space-constrained urban setting

Date on Market:

2025-12-04

Petaluma Flex for Lease - Petaluma/Cotati/Rohnert

1330 Redwood Way in Petaluma, CA offers ±42,000 square feet of fully furnished office, warehouse, and lab space available for sublease through 12/31/2029. The building is divisible to ±11,130 square feet (office), and features dock-high and grade-level loading doors, monument and building signage, and dedicated areas for offices, labs, warehouse, manufacturing, and quality control. The site features convenient access to Hwy 101 and is within walking distance to numerous shopping, dining, or fitness amenities.

Property Type:

Industrial

Date on Market:

2025-12-04

San Francisco Flex for Lease - Mission Bay/China Basin

Situated in the heart of San Francisco’s dynamic Dogpatch neighborhood, 933 20th Street offers an exceptional R&D and lab space designed for innovation and efficiency. This fully renovated property features high ceilings, polished concrete floors, and stylish wood and steel accents that create a modern, industrial aesthetic. The space includes a convenient kitchenette, HVAC, and fiber connectivity, ensuring a seamless operational experience. With a move-in-ready, plug-and-play setup, tenants can hit the ground running. Located just an eight-minute walk from the 22nd Street Caltrain Station and directly across from the newly reimagined Esprit Park, the property provides unmatched access to green space and outdoor amenities. UMU zoning supports life science and medical special uses, making this an ideal choice for tech and research-driven organizations. The sublease runs through August 31, 2026, with the potential for a direct deal, offering flexibility for long-term planning. This rare Dogpatch opportunity combines cutting-edge infrastructure with a vibrant, amenity-rich location.

Date on Market:

2025-12-03

Irvine Flex for Lease - Irvine Spectrum

3 Glen Bell Way is a highly efficient Class A building located in the heart of the Irvine Spectrum — one of Southern California’s most desirable corporate submarkets. Offering direct freeway visibility along the I-5 and immediate access to the 405 Freeway, the property provides exceptional convenience for workforce, executive, and client access. Constructed as a premier corporate headquarters, the building delivers a balanced mix of office, open workspace, and high-clear volume areas with robust power, infrastructure, and abundant parking. Its versatile configuration makes it ideally suited for R&D/Tech, Showroom/Design Center, Life Science, and Industrial/Office occupiers.

Date on Market:

2025-12-03