397 Life Science Properties for Lease in California, USA

Santa Clara Office for Lease - Central Santa Clara

3100 Central Expressway is a ±39,176 SF, two-story state-of-the-art life science facility designed to support cutting-edge research and development. The building features a variety of specialized lab spaces, including fume hoods, workbenches, and dedicated hazardous storage with two H2 Hazardous Storage and Containment facilities. Additionally, the property offers robust backup power systems, executive office suites, and a spacious, modern lobby to enhance functionality and comfort.

Property Type:

Flex

Date on Market:

2025-03-19

Mission Hills Office/Medical for Lease - Eastern SFV

Property Type:

Office

Date on Market:

2025-03-03

Napa Office for Lease - Napa County

50,000 SF, two-story, Class ‘A’ office building with expansive lobby area. Abundant parking; 4/1,000 SF. Immediate access to Highways 29 & 12, and to Napa Airport

Date on Market:

2025-02-25

Irvine Office for Lease - Irvine Spectrum

13,323 SF Freestanding high Image office building in the heart of Irvine Spectrum. Built in 2002 Designed for Corporate Headquarters, Research and Development, Design Professionals, and Creative Industries. High Ceilings with Abundant Natural Light. Short Distance From Los Olivos Marketplace. Across from 24 Hour Fitness. Easy Access to 405 & 5 Freeways & Toll Road

Date on Market:

2025-02-23

Fairfield Office, Office/Medical for Lease - Fairfield/Suisun City

Green Valley Executive Center, located at 5030 Business Center Drive, is a high-impact Class A office property offering approximately 50,000 square feet of professionally maintained, highly adaptable space. This freestanding building makes a bold impression with its prominent street presence, clean architectural lines, and strategic location in the heart of Fairfield’s premier business corridor. It’s the ideal solution for companies seeking a sophisticated headquarters, regional office, or operational hub that combines flexibility, visibility, and long-term value. Set on a spacious, well-landscaped lot with ample onsite covered parking under solar structures, Green Valley Executive Center features a modern layout designed to support both internal productivity and external professionalism. The interior buildout includes multiple private offices, executive boardrooms, collaborative open workspaces, and welcoming reception areas—all finished to a high standard. Whether hosting clients or growing a high-performance team, the space strikes the right balance between comfort and capability. In addition to its premium office environment, the building offers open-span areas ideal for training rooms, operations support, or technical functions. The layout is easily customizable, giving tenants the ability to adapt over time without outgrowing the space. Located just minutes from Interstate 80, Green Valley Executive Center offers quick access to Napa, Sacramento, Walnut Creek and the greater Bay Area. It sits among a strong mix of professional services, technology, and production-based businesses—creating a dynamic, synergistic environment for growth-minded companies. For those seeking a business location that pairs Class A quality with operational flexibility, Green Valley Executive Center at 5030 Business Center Drive delivers on every front. This is more than just a place to work—it’s a foundation for long-term success.

Date on Market:

2025-11-18

Alhambra Industrial for Lease - Western SGV

UPDATED: Four Flexible Warehouse Spaces for Lease – Updated, Functional, and Well-Located. Now leasing four individual warehouse units, each with its own private entrance, offering flexible options to lease individually or as a combined space. These units are ideal for businesses seeking a hybrid of office and warehouse functionality. Property Highlights: • (4) 10’ x 10’ roll-up doors at the rear for efficient loading/unloading • Private entrances for each unit • Fresh paint, new flooring, and updated bathrooms in every unit • Ceiling height approx. 17 ft – perfect for racking or equipment • Private offices, dedicated conference room, and open cubicle areas • Large backyard – suitable for outdoor storage or staging • Six unreserved parking spaces + street parking available Strategic Location: Located in the heart of the San Gabriel Valley, this property offers exceptional access to major transportation corridors and industrial hubs, providing seamless connectivity to greater regional markets. ________________________________________ Ideal for logistics, e-commerce, distribution, or businesses needing integrated office and warehouse solutions. Contact us today to schedule a tour or inquire about availability. ________________________________________

Date on Market:

2025-10-20

San Jose Office for Lease - South San Jose

6140 Hellyer Avenue is a freestanding, single-story commercial property with 4,478 square feet of interior space. Built in 2006, it features 100% office buildout and a modern exterior with strong curb appeal. The building is situated in Hellyer Commons Industrial Park and is zoned Industrial Park (IP), offering a wide range of permitted and conditionally permitted business uses. The design emphasizes professional functionality with a balance of privacy and openness. Inside, you'll find multiple private offices, a large shared kitchen, open team workspaces, and common areas ideal for meetings or collaborative sessions. Optional furniture and tenant improvement packages allow new occupants to customize their environment with minimal hassle. This property stands out for its strategic location and ease of access. It's located just minutes from Highways 101 and 85, providing efficient connectivity throughout the Bay Area. The surrounding area is quiet, green, and offers a peaceful work atmosphere while maintaining proximity to South San Jose’s business districts, restaurants, and retail services. Key building features include: Fully built-out interior with drop ceilings, central HVAC, and private kitchen ADA-compliant design and restroom access Sprinkler system and emergency lighting Secure, single-entry layout for improved access control 36 dedicated surface parking spaces High-speed internet included Bike-friendly amenities and adjacent walking trails Energy-efficient construction with ample window coverage The IP zoning permits a wide range of businesses, including office users, clean-tech and R&D firms, biotech and pharmaceutical companies, and certain medical or therapeutic practices. Businesses seeking to operate as a medical office may apply for a Special Use Permit with the City of San Jose. Approval typically depends on the type of practice (e.g., non-surgical vs. surgical, patient traffic levels, equipment used). The building's layout and infrastructure support this kind of conversion. Whether you're seeking executive offices, research space, or clinical functionality, 6140 Hellyer offers a balanced environment with flexibility, location advantages, and move-in readiness. Reach out today to schedule a tour or request zoning compatibility guidance. Text, call, or email today: Piyush Kothary (408) 656-7643 Kothary@yahoo.com

Date on Market:

2025-07-21

Irvine Flex for Lease - Irvine Spectrum

Date on Market:

2025-01-23

Alhambra Industrial for Lease - Western SGV

Property Highlights This modern, two-story facility features three ready-to-use Clean Rooms, ideal for specialized industries. The versatile space is well-suited for operations in aerospace, biotech, pharmaceuticals, electronics, optics, photonics, medical devices, life sciences, laboratories, and R&D activities. The building also accommodates warehouse and merchandise storage needs and is in move-in-ready condition. Recently renovated, the property includes: * Multiple conference rooms * An open break area * Several private offices An additional space is available at 2001 Chestnut St., Alhambra, CA 91803, located within the same campus and within walking distance. Combined, the two properties offer up to 11,758 sq. ft. of total space. Previously occupied by a leading provider of advanced inertial navigation systems, the facility supported operations across the aerospace, defense, commercial, and industrial sectors. Strategic Location: Conveniently situated near major transportation hubs, business districts, and industrial zones of Los Angeles and the San Gabriel Valley, the property offers ample surface parking for staff and visitors. Note: Lease rate excludes utilities, property expenses, and building services.

Date on Market:

2025-01-21

San Diego Flex for Lease - Sorrento Mesa

This property features a refreshed lobby, updated lighting, and modern office finishes. It includes robust infrastructure to support a 175KW emergency generator, a new roof, and a 3,500 lb service elevator. The facility offers a shipping and receiving area with a roll-up door, remodeled restrooms and showers, and upgraded 3,000-amp electrical service to meet a variety of operational needs.

Date on Market:

2024-12-19

San Diego Office for Lease - Rancho Bernardo

Property Type:

Flex

Date on Market:

2025-12-01

Santa Clara Office, Flex for Lease - North Santa Clara

- Full-building available - Full Kitchen Ground Floor - First Floor 11’ Ceiling Height (Not Clear Height) - Second Floor 10’ to Ceiling Tile 3.000 Amps - Ground Floor Outdoor Patio - Elevator Cold Room in Warehouse - 4 Standard and 1 Accessible Bathroom - LED: 2/29/26 - 7 Cutouts for Roll Up Doors - 5 Showers on First Floor

Date on Market:

2024-11-21

Los Angeles Flex, Industrial for Lease - Inglewood/South LA

St. Andrews Place is fully built-out for Retail, Distribution, Manufacturing and Cultivation with ±15,201 sf of approved production space and ±7,500+ sf of expansion space that totals ±22,701 SF of building on ±33,794 of land. The current configuration allows for flexibilty for any user either looking to expand their cultivation footprint or manufacturing and distribution. Originally built in 1946 the majority of the existing Improvements were completed in 2021. The Property features HVAC throughout the majority of the building, 20 ft clear height, two ground-level doors, brick and concrete block construction, and generous parking for the area. While all compliant uses will be considered, the Property currently offers licensing for Cultivation (and/or Nursery) and Manufacturing allowing an operator speed to market with an existing foundation of partial improvements and regulatory compliance.

Date on Market:

2025-03-24

La Jolla Flex for Lease - Torrey Pines

Date on Market:

2024-12-11

Redwood City Office/Medical for Lease - Foster City/Redwood Shrs

Property Type:

Office

Date on Market:

2024-10-02

San Dimas Office for Lease - Eastern SGV

Rare opportunity to lease a premiere master planned business campus. Freestanding Corporate Headquarters Facility with freeway frontage identity. Located in the Walnut Creek Business Park, a premiere master-planned business community set on park-like grounds in the City of San Dimas. Prestigious business park with corporate neighbors including BioLab and ADP. Located in the Life Science and Tech Corridor. Walnut Creek Business Park is located adjacent to the Foothill (210) and Orange (57) freeways, with exceptional access to the San Bernardino (10) and Pomona (60) Freeways. Building is located adjacent to the on & off ramps. Former flex medical park, up to 200,000 SF available over Four buildings. 502 W. Covina (51,000 SF), 542 W. Covina (71,000 SF), 650 Cliffside (51,500 SF),550 Cliffside (35,000 SF)

Date on Market:

2024-08-30

San Diego Flex for Lease - Sorrento Valley

Discover unparalleled access and convenience at GENESIS-Roselle, a premier ±40,000 SF, two-building life science campus in the heart of Sorrento Valley. Strategically positioned with seamless freeway access, GENESIS-Roselle is being transformed into a hub for San Diego’s biotech community. Set for completion in April 2025, this newly renovated campus will offer state-of-the-art lab spec suites designed to meet the evolving needs of life science companies. With flexible layouts and advanced infrastructure, GENESIS-Roselle is poised to drive innovation and growth in the region. Explore the opportunities and elevate your business at GENESIS-Roselle.

Date on Market:

2024-08-01

San Diego Flex for Lease - Sorrento Mesa

Date on Market:

2024-07-26

Stockton Industrial for Lease

Date on Market:

2024-06-13

San Diego Flex for Lease - Sorrento Valley

Located in the heart of Sorrento Mesa and situated among many of San Diego’s most prestigious life science, medical device, and technology companies. Enjoy quick freeway access and nearby retail offerings coupled with close proximity to the renowned UCSD campus.

Date on Market:

2024-06-11

San Diego Office, Flex for Lease - Sorrento Mesa

Directors Science Park is orchestrating life sciences innovation with over 335,423 square feet of Class A office and lab space across four buildings available for lease in San Diego, California. 4930 Directors Place is a 165,000-square-foot new development suitable for a full building user or can accommodate down to 37,000 square feet. 4955 Directors Place (78,000 square feet) and 4939 Directors Place (62,000 square feet) are two-story lab and office buildings for single users or divisible by floor plate. 4921 Directors Place is delivering a new 22,000-square-foot lab and office spec suite, available in September 2024. On-site amenities at the campus include a fitness center, conference center, café, and outdoor seating areas. Directors Science Park is owned and managed by Healthpeak, a strong, stabilized REIT serving the life science and healthcare industry with a focus on sustainable growth. In the heart of San Diego's life science cluster, Directors Science Park is where accessibility, visibility, and convenience combine. Adjacent to the Vista Sorrento Parkway, Directors Science Park has unmatched signage visibility to over 180,000 vehicles daily. One block away from the Interstate 805 on-ramp with easy connections to Interstate 5, Highways 52 and 26 in minutes. These frequently traveled freeways connect to the greater San Diego area within a 15-minute drive. The San Diego International Airport is 14 miles away, and the Port of San Diego is reached in 17 miles for international and coast-to-coast business needs. Auto-free access to the life science campus is easy through public transportation via the North County Bus and Train (NCTD) Coaster stop in Sorrento Valley, 2 miles away. San Diego, California, is home to some of the world’s leading research and educational institutions, including the University of California, San Diego, Scripps Research Institute, and Sanford Burnham Prebys. Over 2,000 companies in the life sciences industry call San Diego their home.

Date on Market:

2025-05-09

Davis Office, Flex for Lease - Davis/Woodland

Introducing Davis Commerce Park: An Excellent Commercial Lease Opportunity in Davis, California. Comprising of three, one-story buildings (totaling approximately 62,369 square feet) of office, laboratory and flex, this dynamic commercial property offers an exceptional environment for a diverse range of tenants seeking to thrive in the nexus of science, technology and business. Situated in the vibrant city of Davis, California, Davis Commerce Park stands out as a beacon of innovation and opportunity in the heart of the state's research and technology corridor. Positioned just 1.7 miles away from the University of California Davis, Davis Commerce Park enjoys close proximity to one of the nation's foremost research institutions. With its prestigious R1 classification from the American Council of Education, UC Davis stands as a pinnacle of academic excellence. The strategic location of Davis Commerce Park, near UC Davis offers unparalleled advantages for science-focused companies seeking access to top-tier research talent. With over 50% of UC Davis undergraduate students engaged in research and creative projects beyond the classroom, the university serves as a fertile ground for collaboration and talent recruitment. UC Davis is also one of the most published and cited research universities. Davis Commerce Park boasts a carefully curated tenant mix reflecting Davis's dynamic ecosystem. From fitness and wellness facilities to laboratories and corporate offices, our diverse array of tenants spans the spectrum of research, technology, science and business enterprises. This diverse blend ensures a synergistic environment where collaboration flourishes and ideas thrive. Davis Commerce Park's convenient location approximately 17.7 miles from Sacramento International Airport ensures easy access for business travelers, while its proximity to the University of California Berkeley, just 69.6 miles away, further enhances its appeal as a strategic commercial hub in Northern California. The city of Davis itself offers a host of amenities and attractions that appeal to all types. Known for its progressive culture, abundant green spaces, and bike-friendly infrastructure, Davis provides an ideal setting for companies seeking a dynamic and sustainable work environment. Easily accessible by car, bus, walking, and biking, Davis Commerce Park is situated near many bike and walking paths, including the Davis Bike Loop through The Greenbelt, which features most of the town's bicycle infrastructure. Davis Commerce Park is surrounded by numerous restaurants options, making it easy for employers, employees, and clients to grab a quick bite, enjoy lunch, or host a meeting. Davis Commerce Park represents a prime opportunity for forward-thinking companies seeking to establish a foothold in Davis's thriving research and technology landscape. With its premier location, diverse tenant mix, and access to top-tier talent and resources, Davis Commerce Park offers a gateway to success in one of California's most dynamic and innovative communities. The C Building has a great tenant mix of wellness, wet laboratory and children’s sports lessons. The C Building is also sprinklered. Tenants also enjoy fiber optic internet and central HVAC. For property details, zoning, and parcel info, visit Sacramento County’s GIS Viewer: https://generalmap.gis.saccountynet/JSViewer/county_portal.html Not quite what you’re looking for? Give us a call — we may have something else that fits your needs.  Information herein deemed reliable but not guaranteed. References to any values are approximate. Floor Plans and Site Plans are not to scale. Lessee should conduct independent verification of all matters deemed to be material.

Date on Market:

2024-12-02

San Diego Flex for Lease - Sorrento Valley

Date on Market:

2024-05-30

San Diego Coworking for Lease - Rancho Bernardo

Voit Real Estate Services is pleased to present First Class Life Science Incubator Space at Aquillius in Rancho Bernardo. Aquillius is a state-of-the-art shared workspace for life science and medtech companies to rapidly develop, test, prototype and manufacture new technologies. The Aquillius building consists of approximately 25,137 SF and offers the following resources as part of their fully-equipped shared workspace: wet lab space, office space, ISO 7/8 cleanrooms, private lab suites, shared lab equipment, conference rooms, and a prototyping lab with 3D printers and SolidWorks.

Property Type:

Flex

Date on Market:

2024-05-02