447 Life Science Properties for Lease in California, USA

San Carlos Flex for Lease - Belmont/San Carlos

Biotech, lab, pharma, and GMP manufacturing facility designed for advanced life science operations. Situated on a 28,529-square-foot land parcel (APN: 046-161-070), the building features two process/clean rooms — Class 10,000 and 100,000 (or Grade C and D) — equipped with two large floor scales. The facility includes a microbiology lab and a chemistry lab, both supplied with purified water, along with two fume hoods, a large autoclave, and a COP bath. Office accommodations consist of two private offices, a general office area, a server room, and two ADA-compliant restrooms. The property is supported by 1,600 amps of 277/480V power and an 85 kW, 208V/3-phase emergency standby generator. Additional features include a warehouse with HVAC and Title 24 lighting, a large utility room housing four boilers, a pure steam generator system, and oxygen and nitrogen lines. The site provides 17 on-site parking spaces and offers convenient access to Highway 101 via Holly or Whipple Avenue, just minutes from the Alexandria Center for Life Science San Carlos campus. Facility amenities also include a cold room (2–8°C), cooling towers, water chillers, RODI generators, and a waste equalizer/neutralizer system, making it an exceptional opportunity for biotech, pharmaceutical, or GMP manufacturing users.

Date on Market:

2025-11-13

Los Angeles Medical, Retail for Lease - West Hollywood

Date on Market:

2025-10-29

Arcadia Office, Office/Medical for Lease - Western SGV

Santa Anita Medical Plaza 301 W Huntington Dr, Arcadia, CA 91007 Santa Anita Medical Plaza is a premier 79,860-square-foot medical office building located in the heart of Arcadia’s thriving healthcare district. Strategically positioned directly across from USC Arcadia Hospital, with a convenient pedestrian connector, this facility offers unmatched accessibility for both healthcare providers and their patients. The building serves as a critical hub for care in Arcadia and the surrounding communities of Pasadena, Monrovia, and Temple City, drawing over 180,000 patient visits annually. Its proximity to affluent residential neighborhoods ensures a steady and diverse patient base, making it an ideal location for growing or established practices. Don’t miss the rare leasing opportunity in one of Southern California’s most desirable medical markets. ------------------------ PROPERTY FEATURES: PROMINENT LOCATION & ACCESSIBILITY • Minutes from I-210 and other major thoroughfares • Sky bridge to USC Arcadia Hospital Campus • Strong visibility and easy access from Huntington Dr. IDEAL MARKET & SITE LOCATION • The proximity to major throughfares enables this location to conveniently serve: • ~891,000 patients within a 15-minute drive time • A strong patient demographic with a desirable payor mix BUILDING HIGHLIGHTS • 86,762 SF – 6 story medical outpatient building • Strong tenant mix of employed and independent providers • Convenient surface parking • Ease of access and navigation from main roads • Professional ownership and property management • Vacancies in this building are rare ------------------------ 2 Suite Available: ------------------------ Suite 327 • Space Available: 1,938 SF • Lease Rate: Call for details • Lease Type: Call for details • Suite Description: Waiting Room. Reception/Admin. 5 Exam Rooms. 2 Doctor’s Offices. Lab. 2 In-Suite Restrooms. Nurses’ Station. Breakroom and Storage. Floor Plan: https://medwestrealty.com/wp-content/uploads/2023/03/Suite-327-1938-RSF-Floor-Plan.jpg Virtual Tour: https://my.matterport.com/show/?m=cBqgmmJVqUv ------------------------ Suite 413 • Space Available: 940 SF • Lease Rate: Call for details • Lease Type: Call for details • Suite Description: Current lab suite. Able to be converted to clinical. Floor Plan: https://medwestrealty.com/wp-content/uploads/2023/03/Suite-413-scaled.jpg ------------------------ MORE DETAILS: https://medwestrealty.com/property/santa-anita-medical-plaza/ DOWNLOAD BROCHURE: https://medwestrealty.com/wp-content/uploads/2023/03/MW_Santa-Anita-Medical-Plaza-LB17.0_WL.pdf

Date on Market:

2025-11-07

Brisbane Flex for Lease - Brisbane/Daly City

Strategically positioned along Highway 101 with massive freeway signage, the building provides exceptional identity and accessibility. Tenants benefit from a robust infrastructure, including 4000A normal power, a 1250kW generator, 200kVA UPS, and EV charging stations. Shuttle service to Caltrain and BART ensures seamless connectivity to the broader Bay Area, while on-site amenities such as a fitness center, wellness rooms, and café foster a dynamic work environment. Located just 12 minutes from downtown San Francisco, 7000 Marina Blvd offers proximity to major biotech clusters, top-tier dining, and hospitality options. With panoramic Bay views and direct access to the Bay Trail, this property delivers a rare combination of technical sophistication and lifestyle appeal—ideal for companies seeking a flagship presence in one of the nation’s most vibrant life science markets.

Date on Market:

2025-10-27

Los Angeles Medical for Lease - Century City

Property Type:

Office

Date on Market:

2025-10-20

Sunnyvale Flex for Lease

447 Indio is a newly renovated, high-end office and R&D space offering a flexible layout and premium finishes. The office portion comes fully furnished, and the space is market-ready for immediate occupancy.n

Date on Market:

2025-10-16

Berkeley Office for Lease

Date on Market:

2026-03-06

Huntington Beach Industrial for Lease

Date on Market:

2025-10-06

San Diego Flex for Lease - Mira Mesa/Miramar

Property Size: ± 16,072 SF Building ± 1 Acre Lot • Fenced & Secured Parking Area in the Back • Easy Access to I-805 with Close Proximity to I-5, I-15 and Highways 52 & 163 • Located near Westfield UTC, Scripps Memorial Hospital, and UC San Diego

Date on Market:

2025-09-29

Davis Flex for Lease - Davis/Woodland

Positioned just minutes from UC Davis and Downtown, 1910–1920 5th Street offers a rare blend of office, laboratory, and flex space in one of Northern California’s most desirable innovation corridors. This ±40,758 SF two-story facility sits on ±1.5 acres and features robust utilities, lab infrastructure, and flexible layouts ideal for life sciences, biotech, R&D, and high-tech users.

Date on Market:

2025-09-05

Davis Office for Lease - Davis/Woodland

Great window line Efficient suite Plenty of power High speed fiber Building and monument signage available Close proximity to Downtown Davis, UC Davis, numerous commercial & retail facilities and also Interstate 80 Bicycle and greenbelt access adjacent to Property Build-out includes 6 private offices, room for 9 cubicles in open area, large conference room, kitchen, copy/storage room, and small warehouse/storage space.

Date on Market:

2025-08-25

Davis Office/Medical, Flex for Lease - Davis/Woodland

Davis Commerce Park, a dynamic community designed for innovation, productivity, and growth. Perfectly positioned to meet the diverse needs of modern enterprises, our park is home to a vibrant mix of lab, office, flex, gym, cannabis, science, and research tenants. Easily accessible by car, bus, walking, and biking, Davis Commerce Park is situated near numerous bike and walking paths. In addition to its convenient location, Davis Commerce Park is surrounded by a variety of restaurants, making it easy for employers, employees, and clients to grab a quick bite, enjoy lunch, or host a meeting. This center comprises three commercial buildings and offers flexible space to accommodate both small and large businesses. Discover how Davis Commerce Park can be the catalyst for your business success!

Date on Market:

2025-11-12

Westminster Industrial for Lease

This ±69,498 square foot freestanding industrial facility at 7474 Garden Grove Blvd offers a rare blend of visibility, power, and flexibility in the heart of Westminster. 22atBeach Industrial Center is located between the Beach Blvd and Golden West/Knott Ave exits on the Garden Grove (CA-22) Freeway. The site offers unique freeway frontage allowing you to promote your company/brand via a large, internally illuminated tenant sign readily visible to the freeway. Nearby amenities include a variety of dining, shopping and services options at CA 22 and Beach Blvd, and convenient access to public transit and community services—making this a prime location for both workforce convenience and business exposure. The 69,498 sf building features ±6,000 SF two-story office, a large, fenced yard, seven (7) dock-high loading doors—three (3) with pit levelers—and one (1) oversized 14'W x 16'H grade-level door. It is an ideal location for streamlined logistics, aerospace/defense, research and development, and even retail uses. This Premium building includes 2,000 amps of 277/480V power (expandable to 4,000 amps), extra heavy slab and 32-foot minimum clear height. With freeway frontage, parking for up to 120 vehicles and flexible CM zoning supporting both light industrial, commercial and retail uses, this property checks all the boxes for a variety of uses.

Date on Market:

2025-08-21

Millbrae Office for Lease - San Bruno/Millbrae

Divisible office space. Mixed Use Office Building w/Ground Floor retail.

Date on Market:

2025-10-06

South San Francisco Flex for Lease

Join a premier life science campus with the versatile spec suites available for lease at East Grand Avenue in South San Francisco, California. Coming available in September of 2026, these modern spaces include options for 22,250 and 37,532 square feet, offering an ideal canvas for growing teams and institutional businesses. This incredible business destination offers a range of exceptional on-site amenities that form an idyllic and energizing hub for corporate activity. Tenants enjoy access to an activated wellness center, a restaurant, sports courts, and a 300-person conferencing center. There is also abundant on-site parking available with EV charging stations, as well as generous outdoor space with outdoor walking trails and lush landscaping. Situated in a prominent location close to the Highway 101 interchange, this rare offer places businesses in an easily accessible commercial hub. The campus is just a short walk to the SSF Caltrain station, and less than 10 minutes from SFO airport. The surrounding area presents a wide array of desirable urban amenities, including top-rated shopping, dining, recreation, and hotels.

Date on Market:

2025-08-14

Daly City Retail for Lease - Brisbane/Daly City

Property Type:

Flex

Date on Market:

2025-07-30

Sunnyvale Office for Lease

Property Type:

Flex

Date on Market:

2025-11-12

Montebello Office/Medical for Lease - Southeast Los Angeles

Property Type:

Office

Date on Market:

2026-03-06

Fremont Office for Lease

Date on Market:

2025-07-09

Irvine Flex for Lease - Irvine Spectrum

9233 Research Drive | Irvine, CA Upscale Office Sublease | 100 – 6,515 SF Available Located in the heart of Irvine’s thriving business district, 9233 Research Drive offers a flexible sublease opportunity ideal for a variety of professional uses — from corporate offices to churches, non-profits, and community organizations. This upscale space is available in its entirety (6,515 RSF) or can be leased as individual executive offices.

Date on Market:

2025-07-15

Placentia Industrial for Lease - Placentia/Yorba Linda

- Free-standing R& D Type industrial building - Knott's Business Park - Lot area:32,582 SF - Total building area : 16,534SF (1st floor:14,298SF , 2nd floor2,236SF ) * Total 1st and 2nd floor office space:3,744SF * * +/- 585SF at 1st floor area with Ceiling / Lights/ HAVC . * +/- 620SF at 2nd floor :Open Loft area with Kitchen sink and Cabinets is not included in the total building area. - Ceiling height : 22 Ft - Loading: One 10' x 10 ' Ground Level Drive-in Door & One Interior Truck Well (Dock Height loading) - Power: Upgraded (Verify) - Fully Fire sprinklered - Four HAVC units on the roof - Six 4'x 8' smoke Vent & Sky Lights - 31 Parking stalls (Parking ratio:1.87/1,000SF ) - Built In 1986

Date on Market:

2025-07-06

Berkeley Office for Lease

Date on Market:

2025-06-25

Sunnyvale Flex for Lease

Date on Market:

2025-06-16

San Diego Office, Flex for Lease - Mission Valley

Date on Market:

2025-06-03