447 Life Science Properties for Lease in California, USA

South San Francisco Office for Lease

1487 Huntington Avenue is strategically located in South San Francisco with excellent regional connectivity. The property provides easy access to San Francisco, San Jose, and Oakland via nearby highways and public transportation. The site is minutes from SFO International Airport and close to retail, dining, and daily amenities along El Camino Real.

Date on Market:

2026-01-13

South San Francisco Industrial for Lease

432 N Canal Street is a well-located industrial warehouse condominium situated in the highly desirable South San Francisco / Lindenville industrial submarket, one of the Bay Area’s most supply-constrained logistics and R&D hubs. Constructed in 1991, the property is part of an established multi-tenant industrial complex and is designed to support a wide range of warehouse, distribution, light manufacturing, and flex uses. The building benefits from clear ceiling heights of approximately 20–22 feet, grade-level loading, and a functional rectangular layout that maximizes warehouse efficiency while allowing for office or mezzanine build-out. The reinforced concrete construction and full sprinklering provide durability and operational reliability for owner-users or investors alike.

Date on Market:

2026-01-13

Santa Clara Industrial for Lease - Central Santa Clara

FULL RENOVATION COMPLETE of ±10,200 SF industrial R&D building, Single-tenant opportunity, or divisible to ±6,000 SF and ±4,200 SF

Date on Market:

2025-12-16

San Diego Flex for Lease - Sorrento Mesa

Property Type:

Office

Date on Market:

2025-12-15

Torrance Industrial for Lease

Located in the heart of Torrance, this versatile industrial building offers excellent functionality with immediate access to major commercial amenities. The property is just minutes from Torrance Airport and surrounded by a strong mix of nearby retail, restaurants, and shopping centers, making it ideal for a wide range of industrial or service-oriented users. Its prime location and convenient accessibility provide strong appeal for both operations and customers.

Date on Market:

2025-12-04

San Diego Office/Medical for Lease - Sorrento Mesa

Rare owner-user or investment opportunity — a free-standing building in Sorrento Mesa offering the flexibility to occupy all or a portion of the building Abundance of on-site parking and adjacent street parking Exceptional visibility and signage, expansive window line, and elevator-served Zoning allows for a mix of uses Ease of commute with central location, short distance to freeway, and nearby transit options Synergy with adjacent tenants - situated in San Diego’s technology, life science and pharmaceutical hub

Property Type:

Office

Date on Market:

2025-12-03

San Diego Office for Lease - Sorrento Mesa

Date on Market:

2025-09-11

San Carlos Retail for Lease - Belmont/San Carlos

Here’s a summary of what we’re offering, subject to credit and financial review. Two (2) spaces are available for lease, 1 vacant 3,172 sf retail space that can be converted to restaurant with help from the landlord, OR, 1 turn-key 2,050 sf restaurant space. 633 Laurel Street, San Carlos, CA Lease Opportunity 3,172 sf of Rentable Retail, Restaurant, Fitness, Classes, or Office space $3.25/sf NNN + $1.32/sf estimated CAMs = $4.57/sf Gross Rent x 3,172 sf = $14,496.04 Gross Rent per month with 3% annual increases to the base rent and pass through CAMs. 10 Year Lease with 2 x 5 year options. Free Rent During Permitting and Construction Up to 9 months of free rent for tenant to get building permits and to complete construction. Construction Expense Reimbursement from the Landlord (TI Credit) For Restaurants: $47.28/sf TI credit x 3,172 sf = $150,000 in additional free rent credit after the above 9 months of free rent (with strong creditworthiness). 637 Lease Summary 2,050 sf = $3.75/sf NNN + $1.32/sf CAMs = $10,393.50 Gross per month in a NNN lease structure. Lessee shall pay for all water, gas, heat, light, power, telephone, trash and other utilities. 3% annual increases to the base rent and pass through CAMs. 10 Year Lease with 2 x 5 year options. 200 Amps of power, water and gas in place. Upgrade to 400 amps in process. 633 Laurel: Warm Shell Condition 200 Amps of power in place stubbed to suite. Upgrade to 400 amps in process. Water and Gas stubbed to suite. HVAC in place. 2 bathrooms in place We’ve got a fully drafted lease ready to sign upon review of your concept and financials. Average household Income within San Carlos = $335,000 (Within 1 Mile) Daytime Employment Total = 16,490 employees Annual Expenditures: Food and Alcohol = $85,169,403 Annual Total Visits To 600 Block = 1,900,000 In addition to what you see around 633 Laurel today, this is the very prime block in all of San Carlos with the city planning to further enhance both the front of the building and even the back alley parking area. Tour with exclusive broker, Alex Kent. Call 650-793-0541. Further, the city has approved 3,000,000 square feet of Class A Office and Biotech development, mostly by the REIT Alexandria. This means approximately 3,000,000 sf / 250 sf = 12,000 new employees in San Carlos alone. Plus, Redwood City next door approved another 5,000,000 sf, and so on and so on. We’ve also approved about 2,800 new housing units. With 2.5 people per unit, that’s 7,000 additional residents. https://www.sancarlosdowntownplan.com/ ZONING MU-DC-100: Mixed-Use Downtown Core: Allowable uses: retail, restaurant, commercial, and office (front 2,500 sf) uses, as well as res. dev. of up to 100 units/acre. Family Child Care, Small & Large, Residential Care Facilities, Instructional Services/Classes*, Artist Studios*, Vehicle Sales/Leasing*, Banks*, Theaters*, Bars*, Restaurants*, Convenience Grocery Store*, Food Preparation, Bed & Breakfast, Hotels* (if redeveloped with upper floors), Garden Center*, Business and Professional*, Medical and Dental* (if redeveloped with upper floor), General Personal Services*. *See potential limitations or permit process, if any in City of San Carlos municipal code and from a conversation with a city planner. https://www.codepublishing.com/CA/SanCarlos/#!/SanCarlos18/SanCarlos1805.html#18.05

Date on Market:

2025-04-08

Mountain View Flex for Lease

• Renovated Flex/R&D Building • Secure Parking Lot/Yard • 3.3/1,000 Parking • Unparalleled Freeway Access (HWY 101) • $1M Seismic Retrofit Upgrade - Level 3 Rating - Meets the standards of Silicon Valley’s prominent technology companies • Restroom: Two (2) ADA Cores, One including a M & F shower •Renovations: New main Sewer Line 2023. Exterior Paint, Fresh Seal/Slurry, ADA remodel, R&D Loading Doors, Polished Concrete.

Date on Market:

2025-10-29

San Jose Office for Lease - West San Jose

Welcome to 560 S Winchester Blvd, a premier Class A office building located in the heart of West San Jose, adjacent to the vibrant Santana Row. This six-story, 100,841 SF property offers a sophisticated and modern workspace with exceptional amenities and unbeatable access. Built in 2000 and LEED Gold certified, the building blends high-end finishes with sustainable design, making it ideal for forward-thinking businesses. With flexible leasing options including a 9,410 SF direct lease and a 17,132 SF plug-and-play sublease, tenants can enjoy a move-in-ready environment complete with high-end furnishings, conference rooms, labs, and wellness spaces.

Date on Market:

2025-10-28

Cudahy Industrial for Lease - Mid-Cities

Date on Market:

2025-10-23

Reedley Industrial for Lease - E Outlying Fresno County

Date on Market:

2025-10-20

Sunnyvale Office/Medical for Lease

o One Office/Medical Unit 2,694± SF For Lease o Rent is $2.50 PSF Modified Gross Suite 1: 2,694± SF o Front desk receptionist area o Two bathrooms o 5 privates offices o Common area for office cubicles o Conference room with white board o Storage closet o Break room/kitchen with table Property Highlights: • Easy access to HWY 101, 85, 82, 280, 880 & 237. • Ample Parking On site. • Located near numerous fortune 500 high tech companies

Property Type:

Flex

Date on Market:

2025-10-13

Woodland Office/Medical for Lease - Davis/Woodland

Prime downtown location situation in the heart of Woodland's Historic Downtown Corridor. This property offers excellent visibility, workability and convenient access to the new Courthouse, City Hall and County Admin building. Ample parking (fenced with automatic gate).

Property Type:

Flex

Date on Market:

2026-01-02

Carlsbad Flex for Lease

Surrounded by leading biotech and manufacturing firms such as Thermo Fisher Scientific, Beckman Coulter, and TaylorMade, the property benefits from proximity to McClellan-Palomar Airport, Carlsbad Premium Outlets, and a wide array of hospitality and retail amenities including Costco, LEGOLAND, and La Costa Resort. The sublease runs through November 30, 2028, offering stability and flexibility for growing operations. Existing lab and office furnishings may be available upon request, streamlining move-in for qualified tenants.

Date on Market:

2025-10-02

San Carlos Flex for Lease - Belmont/San Carlos

Extensive glass throughout, Full HVAC throughout, Sprinklers

Date on Market:

2025-10-02

Watsonville Office for Lease

60 Penny Lane is a 4422sqft+/- two story single tenant medical-office building in the heart of Watsonville's commercial business-medical district. The building enjoys lush landscape, HVAC, ample parking, high visibility and traffic, and walkability to dining, shops, gym, bus line and more! The interior is in excellent condition and includes an entry waiting area, reception area, multiple private office/exam treatment rooms, a large open floor plan, two private bathrooms with both laundry and shower access, staff areas, water access throughout, tons of natural light, and an upstairs area with open work space and two additional private office/exam treatment rooms.

Date on Market:

2025-09-24

San Diego Flex for Lease - Mira Mesa/Miramar

Date on Market:

2025-09-23

Lompoc Industrial for Lease - Central SB County

This property consist of two 6,000sqft concrete block buildings. 5 units ranging from 1,559sqft up to 3,159sqft. 4 units have roll up doors 2 of which have 2 roll up doors one for parking lot and one for alley access. Zoning is CM- Industrial, also located in the cannabis zone.

Date on Market:

2025-09-18

Oakland Office, Industrial for Lease - Oakland-South/Airport

Welcome to The Loom, a historic cotton mill reborn as Oakland’s most dynamic creative and industrial campus offering FLEXIBLE LEASE TERMS! This is not your average warehouse -- it’s a bold, community-driven environment designed for makers, artists, innovators, builders, and entrepreneurs who are proud to call Oakland home. We offer versatile office and industrial spaces filled with character: soaring ceilings, exposed brick, and abundant natural light available for minimum 1 year lease & up. Many spaces are recently renovated or ready for a custom tenant buildout -- with generous TI packages and concessions available for long-term leases. Leasing at The Loom is not a transaction, it's a chance to integrate into a close-knit and supportive community that’s fueling Oakland’s creative and economic renaissance. Experienced property and community managers will onboard you and cater to your every need, ensuring that you can take full advantage of the rich amenities and full calendar of cultural programming on site, such as artist open studios, live music performances, and more. Amenities include a gym with group classes and personal training, a yoga & wellness studio, and a unique multi-function art lounge that functions as a coffee shop by day and a vibrant bar & event space in the evening. We're down to our last few available spaces, so please contact us now to schedule a tour!

Date on Market:

2025-12-19

Palm Desert Office for Lease - Coachella Valley

Multi-Tenant office building zoned DE-O built in 1998.

Date on Market:

2025-09-15

Mountain View Flex for Lease

• Multiple office & lab areas • Conference rooms • Kitchen • Wet lab • Two clean rooms • Fume hood • DI water system • 4:1000 Parking • Glass Roll Up Door, Shipping & Receiving Area • Easy Access to 101

Date on Market:

2023-09-25

San Diego Industrial for Lease - Kearny Mesa

ARVCO Industrial Park at 7547 Convoy Ct. in San Diego offers a versatile office/warehouse environment designed for functionality and convenience. The property features a professional setting with a combination of office space and warehouse capabilities, making it ideal for businesses seeking operational efficiency. Located in the heart of the Kearny Mesa area, the site provides excellent access to major freeways, including I-805, I-15, and SR-163, ensuring seamless connectivity throughout San Diego County. The building is well-maintained and offers practical amenities to support a range of business needs. Its strategic location near retail, dining, and service options enhances convenience for employees and clients alike. With a layout that accommodates both administrative and storage functions, this property is an excellent choice for companies requiring a balanced mix of office and industrial space in a prime central location.

Date on Market:

2026-02-24

Hollywood Flex for Lease

Introducing 6735 Selma Avenue, formerly the Hollywood headquarters for Panavision. This two-story modern building built in 1996 features soaring ceilings, screening room, ample outdoor space and secured parking, two loading docks, and office space. Announce your brand with this iconic location. This captivating space is more than a building; it’s a statement. The two-story lobby and high ceilings, along with the open floor plan offers boundless possibilities. We envision a space where innovation and inspiration meet, ideal for a headquarters, Flex/R&D space or showroom.

Property Type:

Office

Date on Market:

2025-08-26